Annotation Detail

Information
Associated Genes
MET
Associated Variants
MET UNDEREXPRESSION
Source Database
MMMP
Description
MFG-E8: Milk fat globule EGF-8. MFG-E8 augments melanoma cell resistance to apoptosis, triggers an epithelial-to-mesenchymal transition (EMT) and stimulates immune suppression
MMMP State
inhibited by
MMMP Molecule
MET
MMMP Molecule Alias
c-Met
MMMP Modifier
SU11274
MMMP Relationship
sensitivity to
MMMP Drug
MFG-E8 siRNA
MMMP Model
3
MMMP Reference
Jinushi M, Cancer Res 2008, 68:8889-98
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
MFG-E8 siRNASensitivitytrue