Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Interleukin-24 overcomes temozolomide resistance and enhances cell death by downregulation of O6-methylguanine-DNA methyltransferase in human melanoma cells
- MMMP State
- downregulated by
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Modifier
- IL-24
- MMMP Modifier Alias
- Interleukin-24
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 3
- MMMP Reference
- Zheng M, Mol Cancer Ther 2008, 7:3842-51
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | Sensitivity | true |