Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF UNDEREXPRESSION
- Source Database
- MMMP
- Description
- BMS-345541 is an IKKB inhibitor and thus a NFkB inhibitor (IKKB inhibits IKB, which in turn inhibits NFkB)
- MMMP State
- inhibited by
- MMMP Molecule
- BRAF
- MMMP Molecule Alias
- B-Raf
- MMMP Modifier
- BAY 54-9085
- MMMP Modifier Alias
- BRAF inhibitor
- MMMP Relationship
- no relationship with
- MMMP Drug
- BMS-345541
- MMMP Drug Alias
- NFkB inhibitor
- MMMP Model
- 4
- MMMP Reference
- Yang J, Mol Cancer Ther 2009, 8:636-47
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| BMS-345541 | Resitance or Non-Reponse | true |