Annotation Detail
Information
- Associated Genes
- MITF
- Associated Variants
- MITF EXPRESSION
- Source Database
- MMMP
- Description
- dnMITF (dominant negative MITF) seems to act mainly through Bcl-2 downregulation (MITF upregulates Bcl-2 expression)
- MMMP State
- expressed
- MMMP Molecule
- MITF
- MMMP Molecule Alias
- Microphthalmia-associated transcription factor
- MMMP Relationship
- sensitivity to
- MMMP Drug
- dnMITF gene therapy
- MMMP Model
- 3
- MMMP Reference
- McGill GG, Cell 2002, 109:707-18
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| dnMITF gene therapy | Sensitivity | true |