Annotation Detail
Information
- Associated Genes
- GSTP1
- Associated Variants
- GSTP1 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Combined inhibition of both GSTP1 and MRP1 (ABCC1) with siRNA and sulphinpyrazone, respectively, sensitizes melanoma cells to etoposide
- MMMP State
- downregulated by
- MMMP Molecule
- GSTP1, MRP1
- MMMP Modifier
- GSTP1 siRNA + Sulphinpyrazone
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Etoposide
- MMMP Drug Alias
- VP-16
- MMMP Model
- 3
- MMMP Reference
- Depeille P, Br J Cancer 2005, 93:216-23
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Etoposide | Sensitivity | true |