Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF UNDEREXPRESSION
- Source Database
- MMMP
- Description
- In an in vitro model of human melanoma, silencing of MITF synergically increases the cytotoxic effect of BRAF V600E silencing
- MMMP State
- downregulated by
- MMMP Molecule
- BRAF (V600E)
- MMMP Molecule Alias
- B-Raf (V600E)
- MMMP Modifier
- BRAF V600E siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- MITF siRNA
- MMMP Model
- 3
- MMMP Reference
- Kido K, Cancer Sci 2009, 100:1863-9
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| MITF siRNA | Sensitivity | true |