Annotation Detail

Information
Associated Genes
MITF
Associated Variants
MITF UNDEREXPRESSION
Source Database
MMMP
Description
In an in vitro model of human melanoma, silencing of MITF synergically increases the cytotoxic effect of BRAF V600E silencing
MMMP State
downregulated by
MMMP Molecule
MITF
MMMP Molecule Alias
Microphthalmia-associated transcription factor
MMMP Modifier
MITF siRNA
MMMP Relationship
sensitivity to
MMMP Drug
BRAF V600E siRNA
MMMP Model
3
MMMP Reference
Kido K, Cancer Sci 2009, 100:1863-9
MMMP DNA/mRNA/Protein
mRNA
Drugs
Drug NameSensitivitySupported
BRAF V600E siRNASensitivitytrue