Colorectal Neoplasms

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Information
Disease name
Colorectal Neoplasms
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03833700 Active, not recruiting Phase 1 A Study of E7386 in Participants With Advanced Solid Tumor Including Colorectal Cancer (CRC) March 5, 2019 March 31, 2025
NCT05091346 Active, not recruiting Phase 1/Phase 2 A Study of E7386 in Combination With Pembrolizumab in Previously Treated Participants With Selected Solid Tumors October 27, 2021 September 30, 2025
NCT05451849 Active, not recruiting Phase 1/Phase 2 A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer June 21, 2022 October 30, 2028
NCT00199862 Active, not recruiting N/A Safety Study of Radio-labeled huA33 Antibody in Colorectal Cancer February 2004 June 2027
NCT05754229 Active, not recruiting N/A Accuracy of Real Time Characterization in Artificial Intelligence-assisted Colonoscopy October 1, 2022 September 30, 2025
NCT03519412 Active, not recruiting Phase 2 Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation Status January 23, 2019 December 2024
NCT05143099 Active, not recruiting Phase 2 Phase II Study of Tislelizumab Combined With Cetuximab and Irinotecan in the Treatment of Recurrent, Refractory mCRC February 1, 2021 February 28, 2024
NCT04776148 Active, not recruiting Phase 3 Study of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017) March 29, 2021 September 27, 2024
NCT05328908 Active, not recruiting Phase 3 A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer April 28, 2022 May 31, 2028
NCT05141721 Active, not recruiting Phase 2/Phase 3 A Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer February 12, 2022 March 2027
NCT03153280 Active, not recruiting Phase 1 Dose Escalation Study of Lithium With Oxaliplatin and Capecitabine in Advanced Oesophago-Gastric or Colorectal Cancer January 13, 2022 December 2026
NCT05678257 Active, not recruiting Phase 2 A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer April 18, 2023 March 2025
NCT05189171 Active, not recruiting MicroOrganoSphere (MOS) Drug Screen Pilot Trial in Colorectal Cancer October 25, 2022 December 2025
NCT04683965 Active, not recruiting Phase 2 Pemetrexed and TAS-102 in Combination With Bevacizumab in Refractory Colorectal Cancer January 1, 2021 May 1, 2024
NCT05740137 Active, not recruiting N/A Adenoma Detection Rate in Artificial Intelligence-assisted Colonoscopy October 1, 2022 September 30, 2025
NCT02494791 Active, not recruiting N/A Universal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer July 2015 July 2025
NCT02487992 Active, not recruiting Phase 2 The Study of CIK Plus S-1 and Bevacizumab as Maintenance Treatment for Patients With Advanced Colorectal Cancer July 2015 July 2045
NCT02319928 Active, not recruiting N/A European Polyp Surveillance Trial June 2015 December 2028
NCT04281667 Active, not recruiting Phase 4 Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery March 18, 2020 October 10, 2027
NCT03935282 Active, not recruiting N/A Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors October 1, 2020 March 7, 2025
NCT01516710 Active, not recruiting N/A Oslo Randomized Laparoscopic Versus Open Liver Resection for Colorectal Metastases Study January 2012 December 2025
NCT05728710 Active, not recruiting Outcomes of Perforation After Colorectal Endoscopic Submucosal Dissection September 1, 2019 April 1, 2023
NCT01349881 Active, not recruiting Phase 3 S0820, Adenoma and Second Primary Prevention Trial August 23, 2013 February 1, 2032
NCT00134589 Completed Phase 4 CHOICE: Communicating Health Options Through Information and Cancer Education April 2005 April 2009
NCT00140036 Completed Phase 4 Pharmacogenomics Blood Sampling Protocol For Irinotecan/Fluorouracil/Leucovorin(CPT-11/FU/LV). September 2002 August 2005
NCT00143403 Completed Phase 3 Comparing Irinotecan and 5 FU/FA To 5-FU/FA After Resection Of Liver Metastases For Colorectal Cancer December 2001 September 2009
NCT00168987 Completed Phase 4 Influence of an Oral Nutritional Supplement Rich in Omega-3 Fatty Acids on Functional State and Quality of Life in Malnourished Patients With Gastroenterological Tumors January 2005 June 2007
NCT00188565 Completed Phase 1/Phase 2 Celebrex With Preoperative Chemoradiation - Rectal Cancer March 2004 March 2009
NCT00190515 Completed Phase 3 A Trial Comparing Adjuvant Oral UFT/LV to 5-FU/l-LV in Stage III Colorectal Cancer (JCOG-0205-MF) February 2003 November 2011
NCT00207298 Completed 18F-fluorodeoxyglucose (18F-FDG) Positron Emission Tomography in Oncology June 2005 August 2015
NCT00229554 Completed Survey of ColoRectal Cancer Education and Environment Needs March 2006 March 2008
NCT00236249 Completed Phase 3 Safety and Efficacy Study of Intravenous Lidocaine After Colorectal Surgery: LIDOREHAB May 2005 May 2007
NCT00259844 Completed Phase 2 Effect of TroVax in Patients Having Colorectal Cancer With Liver Metastases Removed June 2004 December 2006
NCT00272051 Completed Phase 3 XENOX - Evaluation of the Efficacy of Xaliproden in Reducing the Neurotoxicity of the Oxaliplatin + 5-FU/LV Chemotherapy July 2002 May 2004
NCT00291486 Completed Phase 1 Capecitabine and 131I-huA33 in Patients With Metastatic Colorectal Cancer October 2003 August 29, 2012
NCT00305188 Completed Phase 3 Evaluation of the Efficacy of Xaliproden (SR57746A) in Preventing the Neurotoxicity of Oxaliplatin / 5FU/LV Chemotherapy. December 2005 October 2009
NCT00311272 Completed Phase 2 Dendritic Cell Vaccination in Patients With Advanced Colorectal Cancer November 2004 September 2007
NCT00313794 Completed Phase 2 Study of Ticilimumab in Patients With Metastatic Colorectal Cancer Whose Disease Had Progressed After Treatment May 2006 June 2008
NCT00361842 Completed Phase 2 Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer July 2006 December 2008
NCT00378482 Completed Phase 2 A Rollover Study for Patients Who Received Tremelimumab in Other Protocols, to Allow the Patients Access to Tremelimumab Until This Agent Becomes Commercially Available or Development is Discontinued. March 5, 2007 October 27, 2023
NCT00385177 Completed Phase 1 Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Advanced Solid Tumors September 2006 May 2009
NCT00001428 Completed Phase 2 A Phase II Study of 5-Fluorouracil Administered as a One Hour Infusion in Combination With Calcium Leucovorin and Interferon Alpha-2A in Advanced Colorectal Cancer February 1995 December 2000
NCT00034034 Completed Phase 1 Acupuncture to Reduce Symptoms of Advanced Colorectal Cancer June 2002 August 2006
NCT00034827 Completed Phase 2 A Multicenter Phase 2 Study of CI-1040 in Patients With Advanced Nonsmall-Cell Lung, Breast, Colon and Pancreatic Cancer January 2002 May 2003
NCT00035087 Completed Phase 2 EPO906 Therapy in Patients With Advanced Colorectal Cancer May 2002 March 2003
NCT00039793 Completed Phase 2 Massage Therapy for Cancer-Related Fatigue March 2001 March 2004
NCT00040599 Completed Phase 1/Phase 2 Safety Study of 90Y-hMN14 to Treat Colorectal Cancer January 2000 January 2004
NCT00041652 Completed Phase 1/Phase 2 Safety Study of hMN14 to Treat Either Colorectal or Breast Cancer February 2000 June 2003
NCT00041808 Completed Phase 1/Phase 2 Magnetic-Targeted Doxorubicin in Treating Patients With Cancer Metastatic to the Liver July 2001 April 2003
NCT00044863 Completed Phase 2 Study of Erbitux (Cetuximab) in Patients With Metastatic Colorectal Carcinoma August 2002 December 2005
NCT00054912 Completed Phase 1 An Open Label Study of a Peptide Vaccine in Patients With Stage III Colon Cancer February 2003
NCT00055419 Completed Phase 2 A Study of Cetuximab in Patients Who Have Stage IV Colorectal Cancer February 2003 August 2004
NCT00056446 Completed Phase 3 Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal Cancer January 2003 January 2007
NCT00056459 Completed Phase 3 Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer. February 2003
NCT00063427 Completed Phase 2 Study Evaluating MAC-321 in Colorectal Cancer February 2004
NCT00068068 Completed Phase 2 Photodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver Metastases October 2003
NCT00072748 Completed Phase 2 Study Evaluating EKB-569 in Advanced Colorectal Cancer October 2004
NCT00077987 Completed Phase 2 Assessment Of Safety And Efficacy Of SU11248 In Patients With Metastatic Colorectal Cancer Who Have Failed Selected Previous Treatments. December 2003 April 2005
NCT00078468 Completed Phase 2 Study of the GARFT Inhibitor AG2037 in Patients With Metastatic Colorectal Cancer Who Failed Treatment December 2003 September 2004
NCT00083720 Completed Phase 2 Erbitux (Cetuximab) Given Alone to Patients With EGFR-Negative Metastatic Colon or Rectal Cancer That is Refractory to Chemotherapy October 2004 April 2008
NCT00083785 Completed Phase 2 Study of the Litx™ System Combined With Chemotherapy in Patients With Colorectal Liver Metastases May 2004
NCT00101686 Completed Phase 3 Trial Of Irinotecan In Combination With Three Methods Of Administration Of Fluoropyrimidine. February 2003 October 2008
NCT00123760 Completed Phase 2/Phase 3 Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Cancer or Suspected Cancer February 2004 December 2008
NCT00132704 Completed An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation August 2004 July 2014
NCT00440310 Completed Phase 3 Phase 3 Trial of Litx™ Plus Chemotherapy vs. Chemotherapy Only Treating Colorectal Cancer Patients With Recurrent Liver Metastases February 2007 October 2011
NCT00460603 Completed Phase 1/Phase 2 Study With AG-013736 Combined With Chemotherapy And Bevacizumab In Patients With Metastatic Colorectal Cancer January 2006 November 2012
NCT00468455 Completed Post-Op Quality of Life After Colorectal Surgery October 2005 May 2008
NCT00474097 Completed Follow-Up Phone Calls After Colorectal Surgery February 2006 December 2007
NCT00491140 Completed Retrospective Study Assessing Molecular Features Predicting Response to Cetuximab December 2006 June 2008
NCT00508690 Completed Phase 3 Trial of Antibiotic Prophylaxis in Elective Laparoscopic Colorectal Surgery: Oral and Systemic Versus Systemic Antibiotics September 2007 December 2011
NCT00531245 Completed Phase 1/Phase 2 A Phase I/II Trial of TS-1 and Oxaliplatin in Patients With Advanced Colorectal Cancer August 2006 March 2009
NCT00532909 Completed Phase 1 Phase I Vandetanib Plus Capecitabine, Oxaliplatin and Bevacizumab for Metastatic Colorectal Cancer July 2006 May 2010
NCT00561470 Completed Phase 3 Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen November 2007 June 2012
NCT00586053 Completed Unprepped CT Colonography August 2000 December 2009
NCT00590434 Completed Yield and Safety of Colonoscopy in Patients Older Than 80 Years August 2006 December 2009
NCT00599924 Completed Phase 1 Study Of Sunitinib Plus FOLFOX In Patients With Solid Tumors September 2005 November 2008
NCT00615056 Completed Phase 2 A Study Combining FOLFOX or FOLFIRI With AG-013736 or Bevacizumab (Avastin) in Patients With Metastatic Colorectal Cancer After Failure Of One First Line Regimen March 2008 April 2012
NCT00623883 Completed N/A Colonoscopic Removal of Aberrant Crypt Foci: a Prospective, Randomized, Blinded Trial January 1999 June 2007
NCT00631410 Completed Phase 1 Study Of Sunitinib In Combination With Folfox In Patients With Colorectal Cancer January 2008 March 2010
NCT00661154 Completed Avastin/[18-F]-5-fluorouracil PET/CT Imaging Feasibility Project February 2008 July 2010
NCT00677781 Completed Impact of Microparticles on Postoperative Complications in Surgical Patients February 2008 January 2010
NCT00692211 Completed N/A Interventions to Improve Colorectal Cancer Screening June 2008 April 2009
NCT00730158 Completed Phase 2 A Phase II Multicenter, Randomized, Placebo Controlled, Double Blinded Clinical Study of KD018 as a Modulator of Irinotecan Chemotherapy in Patients With Metastatic Colorectal Cancer December 2008 June 2018
NCT00764621 Completed Phase 4 Health Economic Evaluation of Primovist-enhanced Liver MRI October 2008 November 2010
NCT00786747 Completed N/A Randomized Controlled Trial of Tailored Interactive Multimedia to Reduce Colorectal Cancer Screening Disparities February 2010 November 2012
NCT00801294 Completed Phase 2 A Phase II Trial of Weekly Alternating Sequential Administration of BIBF 1120 and BIBW 2992 in Patients With Advanced Colorectal Cancer July 1, 2006
NCT00810771 Completed N/A Evaluating a Preference-based Intervention for Increasing Colorectal Cancer Screening February 2009 August 2012
NCT00841191 Completed Phase 1/Phase 2 A Safety, Efficacy and Pharmacokinetic Study of Siltuximab (CNTO 328) in Participants With Solid Tumors March 2009 April 2011
NCT00844064 Completed Phase 1 Safety and Tolerability of AP 12009, Administered I.V. in Patients With Advanced Tumors Known to Overproduce TGF-beta-2 January 2005 November 2011
NCT00851084 Completed Phase 2 Study of Aflibercept And Modified FOLFOX6 As First-Line Treatment In Patients With Metastatic Colorectal Cancer February 2009 January 2012
NCT00860860 Completed Phase 1 Study of Pretargeted Radioimmunotherapy of a Anti-CEA Bispecific Antibody and Lu177-labeled Peptide in Colorectal Cancer July 2009 October 2011
NCT00904839 Completed Phase 2 BIBF 1120 Versus Bevacizumab in Metastatic Colorectal Cancer May 2009 January 2012
NCT00921661 Completed Phase 1 Study of Intravenous Aflibercept in Combination With FOLFIRI in Japanese Patients With Metastatic Colorectal Cancer June 2009 June 2012
NCT00923481 Completed Phase 2 A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H... April 2009 January 2012
NCT00934882 Completed Phase 1 Study to Determine Safety, Pharmacokinetics, Pharmacodynamics of BAY73-4506 in Combination With mFOLFOX6 or FOLFIRI August 2009 April 2012
NCT00947206 Completed N/A Lay Health Workers and Colorectal Cancer Screening Among Chinese Americans September 2009 May 2014
NCT00962494 Completed Phase 2 Cancer: Thriving and Surviving Online Workshop and Study for Cancer Survivors July 2009 December 2011
NCT00965965 Completed N/A Comprehensibility of Colorectal Cancer Screening Educational Materials: Effects on Patient Knowledge and Motivation August 2009 April 2010
NCT00969124 Completed N/A Impact of Experience on Results With the Third Eye Retroscope January 2009 October 2009
NCT00973609 Completed Phase 3 Optimal Maintenance Therapy With Bevacizumab After Induction in Metastatic Colorectal Cancer (CRC) August 2009 August 2015
NCT01044732 Completed N/A Third Eye Retroscope Randomized Clinical Evaluation March 2009 February 2010
NCT01079533 Completed N/A Initiation of Colon Cancer Screening in Veterans or "Start Screening Now" July 2008 July 31, 2014
NCT01082315 Completed A Korean Post-marketing Surveillance Study on Erbitux® in Patients With Metastatic Colorectal Cancer Refractory to Irinotecan-containing Treatment April 2009 July 2014
NCT01082757 Completed Prevalence of the Mutational Status of V-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) in Metastatic Colorectal Cancer (mCRC) in Argentine Patients June 2009 August 2013
NCT01086683 Completed Phase 2/Phase 3 Rehabilitation of Cancer Survivors in Denmark: The Effect of a Psychosocial Rehabilitation Course May 2004 December 2009
NCT01087658 Completed Phase 3 Oral Glutamine in the Prevention of Oxaliplatin-induced Neurotoxicity February 2010 March 2013
NCT01152437 Completed Phase 2 A Study of BIBW 2992 (Afatinib) in Patients With Metastatic Colorectal Cancer June 2010
NCT01198743 Completed Presence of Circulating Tumor DNA in Colorectal Cancer November 2005 May 2017
NCT01220999 Completed Phase 1 A Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer October 12, 2010 June 27, 2012
NCT01260168 Completed Multi-marker Stool Test for Detection of Colorectal Neoplasia: Marker Panel Selection and Technical Development Studies October 2010 November 2013
NCT01276795 Completed N/A Whey Protein-based Enteral Nutrition Support to Improve Protein Economy in Surgical Patients January 2010 August 2010
NCT01289821 Completed Phase 2 First Line Treatment of Metastatic Colorectal Cancer With mFOLFOX6 in Combination With Regorafenib February 2011 June 2014
NCT01290536 Completed Phase 2 Yttrium-90 Radioembolization Using Glass Microspheres (TheraSphere) for Patients With Liver Metastases May 2010 October 2013
NCT01301417 Completed Data Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis February 2011 August 2011
NCT01307878 Completed Phase 3 New Adjuvant Chemotherapy of Asymptomatic Resectable Primary Lesion With Unresectable Liver-limited Metastases June 2012 June 2021
NCT01310699 Completed N/A Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study January 2013 August 2016
NCT01321658 Completed N/A Geriatric Intervention in Frail Elderly Patients With Colorectal Cancer February 2011 October 2015
NCT01333475 Completed Phase 2 MK-2206 and AZD6244 in Patients With Advanced Colorectal Carcinoma March 2011 September 2014
NCT01397747 Completed Multi-Target Colorectal Cancer Screening Test for the Detection of Colorectal Advanced Adenomatous Polyps and Cancer June 2011 May 2013
NCT01413295 Completed Phase 2 Randomized Trial With Dendritic Cells in Patients With Metastatic Colorectal Cancer August 2011 September 2014
NCT01450319 Completed Phase 2 Cetuximab in Refractory Colorectal Cancer With K-RAS Mutated and Favorable FcγRIIa (CD32) Genotype December 2011 December 2014
NCT01453894 Completed N/A Improving Rates of Repeat Colorectal Cancer Screening March 2012 August 2013
NCT01479907 Completed N/A Synbiotics and Gastrointestinal Function Related Quality of Life After Colectomy for Cancer November 2010 September 2015
NCT01492049 Completed N/A R-21 Colorectal Cancer Screening (CRCS) Pilot Trial August 7, 2012 September 12, 2018
NCT01521091 Completed Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions January 2009 December 2010
NCT01521104 Completed The Value of Narrow Band Imaging in Stratifying Patients for Endoscopic Resection or Surgery January 2009 December 2010
NCT01577511 Completed Invasiveness and Chemoresistance of Cancer Stem Cells in Colon Cancer June 12, 2012 October 2017
NCT01584830 Completed Phase 3 Asian Subjects With Metastatic Colorectal Cancer Treated With Regorafenib or Placebo After Failure of Standard Therapy April 2012 January 2016
NCT01588990 Completed Phase 4 A Translational Study of Bevacizumab in Participants With Metastatic Colorectal Cancer June 26, 2012 September 30, 2016
NCT01600209 Completed Exact CRC Screening Test: Stool Sample Collection Study to Support Assay Validation Testing October 2011 September 2012
NCT01604798 Completed Serum Proteomic Profiling for the Early Diagnosis of Colorectal Cancer January 2007 May 2012
NCT01607255 Completed Phase 4 Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT) May 16, 2013 September 30, 2017
NCT01657773 Completed Study of the Association of Nonalcoholic Fatty Liver Disease With Colorectal Malignant Neoplasm April 2012 July 2012
NCT01669109 Completed N/A Hatha Yoga for Patients With Colorectal Cancer September 2012 December 2013
NCT01671592 Completed Phase 1 Safety of Labeled Dendritic Cell (DC) Vaccines and Feasibility of Tracking by Magnetic Resonance Imaging (MRI) January 2013 April 2014
NCT01675128 Completed Phase 1/Phase 2 ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer August 2012 December 2015
NCT01677884 Completed Phase 2 Intra-arterial Hepatic Bevacizumab and Systemic Chemotherapy November 2012 February 2016
NCT01688817 Completed N/A The Magnitude of Effect of PCP Counseling on Participation Rate and Sedation Rate in Colonoscopy-based Screening Program May 2008 May 2010
NCT01700062 Completed Phase 4 Medium Calorie Parenteral Nutrition on Patients With Gastrointestinal Cancer Undergoing Surgery April 2007 December 2008
NCT01719926 Completed Phase 1 Phase I Platinum Based Chemotherapy Plus Indomethacin September 2012 August 2017
NCT01722162 Completed Phase 2 Levocetirizine + Capecitabine + Bevacizumab for Patients With Refractory Colorectal Cancer April 2013 October 2015
NCT01742169 Completed N/A Improving Rates of Colorectal Cancer Screening Among Never Screened Patients January 2013 June 2014
NCT01778595 Completed Colon Cancer Study of Fecal Samples in Shanghai, China January 8, 2013 September 21, 2016
NCT01790139 Completed N/A Oral Iohexol for Fecal/Fluid Tagging for CT Colonography: A Study to Improve Image Quality by Preventing Colonic Bubbles February 2013 January 2014
NCT01793207 Completed Peripheral Blood DNA Methylation Markers for the Early Detection of Colorectal Carcinoma in the Egyptian Population December 2012 March 2015
NCT01819766 Completed Detection of Advanced Colorectal Neoplasia by Stool DNA in Inflammatory Bowel Disease March 2013 January 2017
NCT01843400 Completed Regorafenib Post-marketing Surveillance April 22, 2013 November 14, 2016
NCT01844375 Completed N/A A Trial of Preoperative CHO Drinks on Postoperative Walking Capacity in Colorectal Surgery May 2013 July 2016
NCT01853319 Completed Phase 3 Regorafenib in Subjects With Metastatic Colorectal Cancer (mCRC) Who Have Progressed After Standard Therapy July 24, 2013 June 11, 2018
NCT01875380 Completed Phase 2 Regorafenib in Frail and/or Unfit for Chemotherapy Patients With Metastatic Colorectal Cancer June 2013 April 2016
NCT01877018 Completed N/A Colorectal Cancer Screening in Primary Care September 2010 May 2013
NCT01879904 Completed N/A Evaluation of Endoscopic Submucosal Dissection (ESD) Efficacy February 2010 July 2013
NCT01897584 Completed N/A Effect Inverse Ratio Ventilation on Arterial Oxygenation and Respiratory Mechanics During lapaLAR July 2013 December 2014
NCT01902849 Completed Anesthetic Technique on Immune Response in Colorectal Cancer February 2012 August 2013
NCT01903395 Completed N/A Risk-adapted Screening in First-degree Relatives of Patients With Colorectal Cancer March 2012 December 2015
NCT01909362 Completed Biomarker Analysis for Patients With Metastatic Colorectal Cancer (MCC) July 2013 February 2014
NCT01913223 Completed N/A Endoscopic Sub-mucosal Dissection With the Nestis® Jet Injector System With a Bi-functional Catheter: First Prospective Trial June 2012 July 2014
NCT01972490 Completed Phase 4 Avastin in Combination With Chemotherapy for RAS Mutant Unresectable Colorectal Liver-limited Metastases October 2013 June 2019
NCT01978717 Completed N/A General Anesthesia Combined With Epidural Anesthesia Mitigates the Surgical Stress-related Immunosuppression in Patients With Colorectal Cancer September 2011 September 2012
NCT01996306 Completed Phase 3 A Phase III Study of 2nd-line XELIRI ± Bevacizumab vs. FOLFIRI ± Bevacizumab in mCRC December 2, 2013 June 30, 2018
NCT02038283 Completed Quality of Life of Patients With Colorectal Neoplasm and Cost-Effectiveness Analysis of Colorectal Cancer Screening October 2009 June 2012
NCT02043184 Completed N/A Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR March 2013 July 2016
NCT02047188 Completed Observation of Microvessels and Invasion in Early Colorectal Lesions by NBI January 2010 December 2013
NCT02088333 Completed N/A Effectiveness of an mHealth Colorectal Cancer Screening Intervention June 2014 October 2016
NCT02096354 Completed Phase 2 A Phase 2 Randomized, Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer May 2014 April 13, 2018
NCT02103062 Completed Phase 2 Phase 2 Study With Abraxane (Nab®Paclitaxel) in Metastatic Colorectal Cancer May 5, 2014 January 9, 2015
NCT02106858 Completed Stivarga Regulatory Post-Marketing Surveillance Study in Korea June 25, 2014 May 7, 2019
NCT02124148 Completed Phase 1 A Study of Prexasertib (LY2606368) With Chemotherapy or Targeted Agents in Participants With Advanced Cancer June 18, 2014 February 13, 2020
NCT02141945 Completed Microbiome Test for the Detection of Colorectal Polyps and Cancer March 2014 March 1, 2017
NCT02149108 Completed Phase 3 Nintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1) September 25, 2014 August 25, 2016
NCT02188342 Completed N/A Assessing The Effectiveness of a Preoperative High Intensity Interval Training Programme In Older Colorectal Cancer Patients January 2015 April 2017
NCT02195011 Completed Phase 2 Safety Study of Regorafenib and SIR-Spheres® Microspheres Radioembolization in Patients With Refractory Metastatic Colorectal Cancer With Liver Metastases July 2014 June 4, 2017
NCT02198274 Completed Phase 2 Intravenous BIBH 1 in Patients With Metastatic Colorectal Cancer February 2000
NCT02219893 Completed Phase 1/Phase 2 Immunotoxin in Peritoneal Carcinomatosis- ImmunoPeCa Trial August 2014 December 10, 2016
NCT02228200 Completed N/A Nurse-led Care Program for Cancer Patients in Chemotherapy Day Center June 2012 January 2014
NCT02231086 Completed Phase 3 Adjuvant HIPEC in High Risk Colon Cancer March 2015 June 1, 2019
NCT02246049 Completed Phase 2 A Multicenter, Clinical Study of FOLFOXIRI With Bevacizumab As First-line Therapy in Patients With mCRC May 2014 February 2017
NCT02298946 Completed Phase 1 AMP-224, a PD-1 Inhibitor, With Stereotactic Body Radiation Therapy in Metastatic Colorectal Cancer November 21, 2014 March 7, 2017
NCT02321813 Completed N/A Direct Improvement of Quality of Life Using a Tailored Pathway With Quality of Life Diagnosis and Therapy: Randomised Trial in Colorectal Cancer Patients January 2014 June 2017
NCT02343601 Completed Phase 3 Perioperative Hemodynamic Optimization Using the Photoplethysmography in Colorectal Surgery December 2014 December 2016
NCT02345889 Completed N/A A 4-arm Clinical Trial of Fuse®, EndoCuff™, EndoRings™ and Standard Colonoscopy February 2015 December 2017
NCT02347735 Completed Predictive Factors for Anastomotic Leakage After Colorectal Surgery August 2015 July 1, 2021
NCT02347852 Completed Assessment of Physical Activity During Therapy With Regorafenib for Metastatic Colorectal Cancer January 20, 2015 September 8, 2016
NCT02368236 Completed N/A Facilitating Risk-Appropriate Colorectal Cancer Testing - Testing the Cancer Risk Intake System (CRIS) December 2008 November 2012
NCT02384759 Completed Phase 2 Aflibercept +/- LV5FU2 in First Line of Non-resectalbe Metastatic Colorectal Cancers May 2015 June 2021
NCT02399410 Completed Phase 2 Perioperative Chemotherapy With Bevacizumab for Colorectal Carcinomatosis November 4, 2015 November 9, 2023
NCT02406547 Completed N/A Study of Narrow Band Imaging in the Characterization of Serrated Lesions March 2015 April 2016
NCT02412683 Completed Neurotoxic Symptoms in Adjuvant Chemotherapy in Patients With Colorectal Cancer January 2014 September 2016
NCT02448693 Completed N/A Study of Narrow Band Imaging in the Characterization of Residual Neoplasia After Endoscopic Piecemeal Mucosal Resection May 2015 May 2016
NCT02456285 Completed Colorectal Cancer With Liver-limited Synchronous Metastases: an Inception Cohort Study of Standardised Care Pathways May 20, 2015 April 30, 2017
NCT02465502 Completed Phase 2 Regorafenib in Subjects With Antiangiogenic-naive and Chemotherapy-refractory Advanced Colorectal Cancer July 21, 2015 December 11, 2017
NCT02483832 Completed N/A Message Framing and Colorectal Cancer Screening February 2015 August 24, 2015
NCT02484079 Completed N/A Comparative Effectiveness of Hot Versus Cold Snare Polypectomy of Small Colorectal Polyps May 18, 2015 December 31, 2022
NCT02485561 Completed N/A Evaluating Strategies to Present Colon Cancer Screening Information June 1, 2015 January 31, 2017
NCT02486094 Completed Study of PRoliferation and Apoptosis in Rectal Cancer, Predictive & Prognostic biOmarkers: Histopathology and Imaging June 2015 June 7, 2017
NCT02491593 Completed Quantitative Immunochemical Fecal Occult Blood Test in Symptomatic Patients April 2014 March 1, 2017
NCT02494037 Completed The Canadian/US Integrative Oncology Study January 1, 2015 December 1, 2023
NCT02499939 Completed N/A Ultrasound Therapy and Therapeutic Exercise for Chemotherapy Induced Peripheral Neuropathy (CIPN) February 10, 2016 July 1, 2018
NCT02502760 Completed N/A Using Multimodal Prehabilitation to Improve Outcomes for Frail Patients Undergoing Resection of Colorectal Cancer August 2015 June 19, 2019
NCT02503696 Completed Sample Collection Study to Evaluate DNA Markers in Subjects With Inflammatory Bowel Disease (IBD) September 2014 June 2016
NCT02509143 Completed N/A Acupuncture for Postoperative Nausea and Vomiting in Patients Undergoing Colorectal Surgery July 2015 December 2016
NCT02564835 Completed N/A Effects of Yoga on Cognitive and Immune Function in Colorectal Cancer September 2015 September 2017
NCT02599103 Completed N/A The Effects of Various Cooking Oils on Health Related Biomarkers in Healthy Subjects September 2013 September 2015
NCT02650661 Completed N/A Efficacy of a Smart Management Strategy for Health (SMASH) Program for Overcoming Cancer Crisis and Growing Positively November 23, 2015 January 2018
NCT02656524 Completed Stivarga Real Life Evidence in Hungary July 1, 2016 February 15, 2017
NCT02674815 Completed N/A Preoperative High Intensity Interval Training: The PHIIT Trial February 2016 December 2016
NCT02698462 Completed N/A Adding Family History of Colorectal Cancer to the Dutch FIT-based Screening Program April 2016 May 15, 2018
NCT02748811 Completed N/A Effect of Geriatric Intervention in Frail Elderly Patients Receiving Chemotherapy for Colorectal Cancer May 2015 September 2019
NCT02776683 Completed Phase 3 Open-label, Single Arm Trial of BI 695502 in Patients With Previously Untreated Metastatic Colorectal Cancer June 8, 2016 October 3, 2018
NCT02800330 Completed Phase 4 The Effects of the Proton Pump Inhibitor Esomeprazole on the Bioavailability of Regorafenib May 2016 February 2018
NCT02845973 Completed Study of Fecal Bacteria in Early Diagnosis of Colorectal Cancer January 2012 July 2017
NCT02848079 Completed Phase 1/Phase 2 TAS-OX for Refractory Metastatic Colon Cancer October 31, 2016 June 2, 2020
NCT02859155 Completed N/A Prognostic Factors Affecting Outcomes in Multivisceral en Bloc Resection for Colorectal Cancer January 2009 April 2016
NCT02889679 Completed N/A Underwater Resection of Non-pedunculated Colorectal Lesions September 2016 October 2018
NCT02892721 Completed N/A Performance and Evaluation for CT Colonography Screening April 20, 2017 March 31, 2020
NCT02933307 Completed N/A Continuous Monitoring on the General Ward April 2015 September 2016
NCT02963207 Completed N/A MS Versus NICE for Colorectal Lesions June 2013 June 2015
NCT02969681 Completed Phase 3 Vitamin C Intravenously With Chemotherapy in Advanced Colorectal Cancer January 2017 December 30, 2020
NCT03010813 Completed N/A A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery December 2016 October 2017
NCT03021135 Completed N/A Conventional Endoscopic Mucosal Resection vs Underwater Resection for Colorectal Non-pedunculated Colorectal Lesions June 7, 2018 January 19, 2022
NCT03037385 Completed Phase 1/Phase 2 Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors March 17, 2017 March 21, 2024
NCT03041532 Completed N/A Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme October 1, 2017 November 30, 2018
NCT03072472 Completed N/A BowelScope: Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities February 14, 2017 February 13, 2018
NCT03082911 Completed N/A A Telephone Intervention to Improve Participation in a Screening Program. March 13, 2017 December 20, 2017
NCT03142516 Completed Phase 2 FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status October 31, 2017 January 21, 2021
NCT03155542 Completed Alcohol Intake, Alcohol Metabolizing Enzymes Gene Polymorphisms and the Risk of Colorectal Cancer December 2016 March 29, 2017
NCT03190616 Completed Phase 2 Apatinib in Refractory Colorectal Cancer July 1, 2017 December 30, 2019
NCT03206073 Completed Phase 1/Phase 2 A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer December 7, 2017 June 30, 2022
NCT03246321 Completed Phase 2 PIPAC for Peritoneal Metastases of Colorectal Cancer October 1, 2017 October 1, 2019
NCT03258450 Completed N/A Effectiveness of a Psychosocial Intervention for Colorectal Cancer November 1, 2017 August 31, 2019
NCT03281447 Completed N/A Nurse Navigation Versus Current Care Coordination During Colorectal Cancer Trajectories February 26, 2016 December 31, 2018
NCT03367611 Completed N/A Use of iFOBT in Patients Presenting With Alarm Symptoms of Colorectal Cancer March 15, 2018 December 31, 2019
NCT03386825 Completed Metastatic Colorectal Cancer Patients With Long-term Response to Regorafenib January 31, 2018 May 1, 2018
NCT03428958 Completed Phase 1/Phase 2 A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment October 16, 2018 March 21, 2024
NCT03473327 Completed Immunological and Oxidative Stress Response in Relation to Abdominal Cancer Surgery January 2016 December 2017
NCT03477019 Completed Phase 1/Phase 2 Ultrasound-enhanced Delivery of Chemotherapy to Patients With Liver Metastasis From Breast- and Colorectal Cancer November 12, 2018 December 31, 2022
NCT03579732 Completed EffectiveNess of Low Dose Aspirin in GastrointEstinal Cancer Prevention - Taiwan June 29, 2018 September 30, 2019
NCT03587818 Completed N/A Person-Centred Information and Communication for Patients Undergoing Colo-Rectal Surgery - the PINCORE Project November 1, 2012 April 30, 2016
NCT03595904 Completed N/A Internet-Based Motivational Interviewing for Colonoscopy November 20, 2017 May 8, 2020
NCT03631407 Completed Phase 2 Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046) September 24, 2018 June 8, 2021
NCT03698461 Completed Phase 2 Treatment of Colorectal Liver Metastases With Immunotherapy and Bevacizumab May 15, 2019 October 24, 2023
NCT03763266 Completed N/A Low Residue Diet During 3 Days vs 1 Day Prior Colonoscopy December 6, 2018 January 20, 2020
NCT03817866 Completed Chromogranin A as Blood Marker in Cancer Patients January 29, 2019 December 14, 2021
NCT03840590 Completed N/A Adenoma Detection Rate Using AI System in China July 10, 2019 December 5, 2019
NCT03853278 Completed N/A Self-management Support for Colorectal Cancer Survivors Colorectal Cancer Survivors: A Mixed-methods Study January 15, 2018 August 31, 2021
NCT03892252 Completed Characteristics of Gut Microbiota in Patients With Colon Cancer of Different Traditional Chinese Medicine Syndromes March 10, 2019 February 20, 2020
NCT03902899 Completed N/A Increasing Serrated Polyp Detection With a Brief Awareness Training January 1, 2014 October 26, 2018
NCT03924349 Completed N/A ICG-coated Endoscopic Clip for Tumor Localization July 8, 2019 November 26, 2019
NCT03948763 Completed Phase 1 A Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001) June 26, 2019 August 25, 2022
NCT03958500 Completed N/A The Problem of Colorectal Anastomosis Safety April 1, 2019 January 31, 2022
NCT04017845 Completed Early Phase 1 Screening for Colorectal Cancer in Average and High Risk Population April 1, 2015 October 30, 2017
NCT04080414 Completed N/A Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of CRC Recurrence August 2, 2019 February 12, 2021
NCT04080843 Completed Phase 2 Anlotinib Hydrochloride Capsules Combined With CAPEOX in RAS and BRAF Wild-type mCRC Patients November 15, 2019 July 1, 2022
NCT04129177 Completed Reduction of Surgical Site Infections in Elective Colorectal Surgery After the Implementation of a Bundle of Care. October 1, 2018 June 30, 2020
NCT04166383 Completed Phase 2 VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC) August 9, 2020 December 31, 2022
NCT04180033 Completed N/A Diagnostic Yield of Colonoscopy Surveillance in Testicular Cancer Survivors Treated With Platinum-based Chemotherapy February 18, 2020 November 25, 2022
NCT04192565 Completed N/A A Prospective Investigation of the ColubrisMX ELS System September 9, 2020 March 29, 2021
NCT04291976 Completed N/A Back-to-back Endoscopy Versus Single-pass Endoscopy and Chromoendoscopy in IBD Surveillance March 13, 2020 November 7, 2023
NCT04292366 Completed N/A Optimising Colorectal Cancer Screening Participation October 2, 2020 May 10, 2021
NCT04357158 Completed N/A Breath Analysis as an Additional Test for Colorectal Cancer Screening to Reduce the Number of Unnecessary Colonoscopies May 25, 2020 July 5, 2022
NCT04389957 Completed Improving Colonoscopy Quality for Colorectal Cancer Screening in the National VA Healthcare System June 1, 2020 March 29, 2024
NCT04395352 Completed Effectiveness of Endocuff Vision in Improving ADR November 1, 2018 November 30, 2019
NCT04418843 Completed N/A Cold EMR Vs Standard EMR for the Treatment of Large Nonpedunculated Homogeneous Colorectal Lesions June 8, 2020 March 31, 2023
NCT04490551 Completed N/A Combining Risk Factors and Faecal Immunochemical Testing in Colorectal Cancer Screening: a Randomized Controlled Trial December 5, 2019 June 1, 2021
NCT04493905 Completed Effects of Anesthetic Techniques on Time to Start of Adjuvant Chemotherapy Following Surgery for Colorectal Cancer December 1, 2021 March 31, 2024
NCT04673136 Completed N/A Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program. April 1, 2021 March 31, 2022
NCT04722055 Completed A Multicenter Clinical Trial of Stool-based DNA Testing for Early Detection of Colon Cancer in China January 26, 2021 August 8, 2022
NCT04748744 Completed Value of Butyrylcholinesterase as a Marker of Surgical Site Infection Following Surgery for Colorectal Diseases November 6, 2019 May 1, 2023
NCT04831814 Completed N/A Narrow Band Imaging in Diagnosis of Colorectal Polyps April 4, 2019 January 14, 2021
NCT04875793 Completed N/A Effectiveness of an Integrated Colorectal Cancer Screening in Saudi Arabia: A Pragmatic Randomized Trial June 10, 2021 July 10, 2022
NCT04898842 Completed N/A Feasibility Study of a 4 Stage Bowel Obstruction Cancer Diet March 2, 2021 November 2, 2022
NCT04921488 Completed N/A Interest of Artificial Intelligence in Cancer Screening Colonoscopy October 21, 2021 January 25, 2023
NCT04930016 Completed Quality of Life and Survival of Patients With Colorectal Cancer 5 Years After Surgery - Follow-up of the RCT DIQOL April 14, 2021 October 7, 2021
NCT04980443 Completed N/A Evaluation of a New Blood-based Test to Detect Colorectal Cancer and Its Precursors August 3, 2021 November 1, 2022
NCT05013125 Completed N/A ENDO-AID Assisted Tandem Colonoscopy RCT August 18, 2021 April 30, 2023
NCT05022511 Completed N/A Three Birds With One Stone September 1, 2021 September 1, 2023
NCT05113134 Completed N/A Transvaginal Versus Transabdominal Extraction of Laparoscopically-excised Specimen March 2, 2015 July 24, 2020
NCT05115916 Completed N/A Effect of Patient Portal Messaging Before Mailing Fecal Immunochemical Testing Kit on Colorectal Cancer Screening Rates August 28, 2019 December 20, 2020
NCT05178745 Completed A Prospective Observational Cohort Study Evaluating Resection Rate in Patients With Metastatic Colorectal Cancer Treated With Aflibercept in Combination With FOLFIRI - Observatoire résection September 7, 2016 May 27, 2022
NCT05184751 Completed Incidence and Risk Factors of Early Onset Colorectal Cancer January 1, 2012 December 1, 2021
NCT05275530 Completed N/A The Impact of Choice on Colorectal Cancer Screening February 21, 2022 November 21, 2022
NCT05281159 Completed N/A Increasing Engagement With Messages Regarding CRC Screening Among Adults Aged 45-49 February 21, 2022 November 21, 2022
NCT05374369 Completed Retrospective Analysis of Colorectal Cancer Screening Results March 29, 2022 April 28, 2022
NCT05477836 Completed N/A Feasibility and Safety of MiWEndo-assisted Colonoscopy October 18, 2022 November 25, 2022
NCT05497726 Completed N/A Fluorescent Sentinel Lymph Node Identification in Colon Carcinoma Using Intravenous Bevacizumab-800CW January 27, 2023 October 10, 2023
NCT05498051 Completed N/A Fluorescent Sentinel Lymph Node Identification in Colon Carcinoma Using Submucosal Bevacizumab-800CW. September 1, 2022 June 1, 2023
NCT05502276 Completed N/A Full Thickness Resection or Endoscopic Submucosal Dissection for Difficult Colorectal Lesions. January 1, 2019 September 30, 2022
NCT05601609 Completed Are Sporadic Colorectal Cancers in Young Distinct From Elderly? November 11, 2020 August 2, 2022
NCT05617378 Completed Exploring the Risk Factors for Colorectal Cancer in Our General Population Using Asian Pacific Screening Score: a Survey From Pakistan November 1, 2022 December 31, 2023
NCT05773248 Completed ERAS in Colorectal Surgery: Benefits of Late Adoption March 13, 2023 April 30, 2023
NCT05963724 Completed N/A Real-Time CAD for Colonic Neoplasia: A RCT September 1, 2022 May 27, 2023
NCT06010225 Completed Effects of Implementing an ERAS Protocol May 1, 2020 May 1, 2023
NCT06271980 Completed Early-Onset Colorectal Cancer Recurrence April 15, 2023 February 1, 2024
NCT06427109 Completed Omega-3 Fatty Acid and Colorectal Adenoma November 1, 2021 February 21, 2024
NCT05575765 Enrolling by invitation Clinical Validation of Multimodal Digestive Endoscopy August 14, 2023 December 2024
NCT05888623 Enrolling by invitation Computer Assisted Detection of Neoplasia During Colonoscopy Evaluation October 1, 2022 September 30, 2024
NCT01538680 No longer available Regorafenib in Subjects With Metastatic Colorectal Cancer (CRC) Who Have Progressed After Standard Therapy
NCT05653960 Not yet recruiting Clinical Outcomes After EMR or ESD of Colorectal Neoplasms - A Multicenter Registry December 1, 2023 December 31, 2033
NCT06177288 Not yet recruiting N/A DEBIRI Combined With Chemotherapy and Bevacizumab in the Treatment of Unresectable Colorectal Cancer Liver Metastases January 1, 2024 May 1, 2025
NCT05636085 Not yet recruiting Clinical Performance of the Mainz Biomed Colorectal Cancer Screening Test for Colorectal Cancer and Advanced Adenoma June 1, 2023 April 1, 2025
NCT06380816 Not yet recruiting Phase 1/Phase 2 A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer May 2024 November 2029
NCT03221608 Not yet recruiting Phase 3 Clinical Analysis of HIPEC for T4 Colorectal Cancer After Surgery August 1, 2017 August 1, 2024
NCT05587088 Not yet recruiting Phase 1/Phase 2 Evaluation of the Safety and Efficacy of Esperanza Extract (PA001) December 15, 2022 June 15, 2023
NCT05551247 Not yet recruiting Phase 2 Envafolimab Combined With Endostatin in Recurrent or Metastatic MSS-type Colorectal Cancer September 15, 2022 June 28, 2024
NCT06079242 Not yet recruiting Observational Study for SIR-Spheres Therapy for the Treatment of Unresectable Metastatic Liver Tumors From Primary Colorectal Cancer October 15, 2023 April 1, 2027
NCT06067620 Not yet recruiting N/A Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy August 1, 2024 December 31, 2026
NCT06061432 Not yet recruiting N/A Endoscopic Ultrasound- Guided Hartmann Reversal Procedure December 1, 2023 December 31, 2026
NCT05353582 Not yet recruiting Phase 2 Preoperative Systemic Therapy for Colorectal Cancer Peritoneal Metastases June 1, 2022 July 1, 2025
NCT06024356 Not yet recruiting Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for Locally Advanced Mid-low Rectal Cancer September 20, 2023 March 30, 2024
NCT06411756 Not yet recruiting N/A Physical Activity Centers Empowerment June 1, 2024 September 1, 2025
NCT05193292 Not yet recruiting Phase 2 Camrelizumab Combined With Trastuzumab and Chemotherapy in Patients With HER2-positive Advanced Colorectal Cancer January 2022 January 2025
NCT05414383 Not yet recruiting A Prospective Study to Evaluate the Diagnostic Accuracy of Computer-aided Diagnosis (CADx) System in Real-time Characterization of Colorectal Neoplasia December 2024 December 31, 2025
NCT05832372 Not yet recruiting Esophagogastric Histopathology Potentially Guided Patients Younger Than 50 Years Old to Undergo Colonoscopy Earlier May 1, 2023 May 27, 2023
NCT05810805 Not yet recruiting Measurement and Analysis of Gas Composition in Digestive Tract April 1, 2023 March 2, 2024
NCT05333809 Not yet recruiting Phase 2 Pembrolizumab and Disitamab Vedotin in HER2-expressing Metastatic Colorectal Cancer July 1, 2022 July 1, 2025
NCT05426811 Not yet recruiting Phase 1/Phase 2 Regorafenib Plus Raltitrexed as Third-line Treatment in Advanced Colorectal Cancer Patients July 1, 2022 December 30, 2025
NCT06356714 Not yet recruiting Phase 2 Nocardia Rubra Cell Wall Skeleton in Combination With Prior Second- or Third-line Regimens for the Treatment of Potentially Hazardous Colorectal Cancer SD Status May 1, 2024 August 1, 2025
NCT06370949 Not yet recruiting The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block May 1, 2024 November 30, 2024
NCT03923335 Not yet recruiting The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal Cancer April 30, 2019 December 31, 2026
NCT05730595 Not yet recruiting N/A Fluorescence Laparoscopic Navigation for Rectal Cancer and Sigmoid Colon Cancer September 1, 2023 June 1, 2027
NCT06447662 Not yet recruiting Phase 1 A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation. July 28, 2024 July 12, 2028
NCT05405673 Recruiting Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia June 29, 2022 December 31, 2025
NCT02869503 Recruiting Institut Paoli Calmettes Colorectal Cancer Database January 2001 December 2030
NCT02885753 Recruiting Phase 3 Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the Liver December 2016 September 2027
NCT05414448 Recruiting N/A Combination of Artificial Intelligence and Mucosal Exposure Device to Enhance Colorectal Neoplasia Detection March 7, 2023 December 31, 2025
NCT05448846 Recruiting N/A Exercise Program for Colorectal Older Patients April 8, 2022 December 2024
NCT05457244 Recruiting N/A Safety and Performance of the da Vinci SP® Surgical System in Colorectal Procedures September 1, 2023 December 31, 2025
NCT06342440 Recruiting Early Detection of Advanced Adenomas and Colorectal Cancer March 15, 2020 December 15, 2025
NCT05493683 Recruiting Phase 2 Disitamab Vedotin Combined With Tislelizumab in Advanced HER2 Positive Colorectal Cancer August 1, 2022 July 2025
NCT06354595 Recruiting N/A Feasibility Study of Multidimensional Rehabilitation in the Metaverse March 1, 2024 May 1, 2024
NCT05517343 Recruiting N/A Impact of Real-time Notification of Colonoscopic Optical Diagnosis on Patients' Anxiety and Depression After Polypectomy August 20, 2022 August 31, 2025
NCT05542030 Recruiting N/A CAD EYE Detection of Remaining Lesions After EMR September 12, 2022 September 12, 2024
NCT05571293 Recruiting Phase 2 Combination Immunotherapy in Colorectal Cancer March 17, 2023 December 2025
NCT05571839 Recruiting Phase 1 A Study of SGN-BB228 in Advanced Melanoma and Other Solid Tumors January 3, 2023 September 30, 2028
NCT03303833 Recruiting The GEOLynch Cohort Study July 1, 2006 December 2030
NCT05576506 Recruiting Application of Hyperspectral Imaging Analysis Technology in the Diagnosis of Colorectal Cancer Based on Colonoscopic Biopsy October 8, 2022 December 31, 2023
NCT05592886 Recruiting N/A A Novel Oral Synbiotic Formula in Reducing Adenoma Recurrence and Colorectal Neoplasia-related Bacterial Gene Markers December 15, 2022 December 31, 2025
NCT03485209 Recruiting Phase 2 Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors June 25, 2018 November 30, 2026
NCT06379880 Recruiting N/A Impact on Quality of Life and Health of the CONTINUUM+ CONNECT Remote Monitoring Solution April 25, 2024 February 25, 2025
NCT05612347 Recruiting N/A Colonoscopy vs Stool Testing for Older Adults With Colon Polyps June 14, 2023 December 31, 2033
NCT03597581 Recruiting Phase 1 A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer June 5, 2018 December 31, 2024
NCT03602677 Recruiting N/A Indocyanine Green Fluorescence Imaging in Prevention of Colorectal Anastomotic Leakage September 24, 2018 December 1, 2023
NCT03659448 Recruiting Phase 3 Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer June 17, 2019 December 2024
NCT05638243 Recruiting Evaluation of a Model for the Early Diagnosis of Colorectal Cancer by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA to the Community Colorectal Cancer Screening Program August 20, 2022 September 2025
NCT05647122 Recruiting Phase 1 First in Human Study of AZD9592 in Solid Tumors December 22, 2022 October 29, 2025
NCT05655780 Recruiting The Role of the Tumor Molecular Profile (CMS), UGT1A1 Genotype and Beta-glucuronidase Activity of the Intestinal Microbiota for Treatment Efficiency, Toxicity, Survival and Quality of Life in Patients With Metastatic or Unresectable Colorectal Cancer During Irinotecan-based Systemic Treatment January 9, 2023 December 2028
NCT03868228 Recruiting Phase 1/Phase 2 PIPAC for the Treatment of Colorectal Peritoneal Metastases February 5, 2019 September 30, 2024
NCT03914820 Recruiting N/A Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. CHECK Study. June 19, 2020 June 1, 2025
NCT03919461 Recruiting Phase 2 Colorectal Metastasis Prevention International Trial 2 February 28, 2019 February 28, 2027
NCT05736731 Recruiting Phase 1/Phase 2 A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Subjects With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression April 28, 2023 December 2028
NCT00927680 Recruiting Familial Colorectal Cancer Registry in Hispanics July 2007 January 2026
NCT03998644 Recruiting Colorectal Cancer Associated Host and Microbiome Study December 2015 December 2025
NCT04008797 Recruiting Phase 1 A Study of E7386 in Combination With Other Anticancer Drug in Participants With Solid Tumor July 11, 2019 March 15, 2027
NCT05768178 Recruiting Phase 2/Phase 3 DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. March 1, 2023 October 2029
NCT05770102 Recruiting Phase 2/Phase 3 DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Teenage/Young Adults and Paediatric Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition October 25, 2023 October 2029
NCT06400472 Recruiting Phase 1 A Study of LY4170156 in Participants With Selected Advanced Solid Tumors May 6, 2024 April 2027
NCT04084249 Recruiting N/A ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial January 1, 2020 June 30, 2028
NCT05785975 Recruiting N/A Effectiveness of Modified Integrated Colorectal Cancer Screening System in Saudi Arabia June 15, 2023 December 30, 2023
NCT04130971 Recruiting Predicting Colorectal Cancer - Tissue Samples to Evaluate Tumour Characteristics and Treatment Response February 1, 2019 December 31, 2027
NCT05786716 Recruiting Phase 2/Phase 3 DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations March 7, 2023 October 2029
NCT05825664 Recruiting N/A Underwater Versus Conventional Endoscopic Mucosal Resection in the Treatment of Non-pedunculated Colorectal Polyps April 7, 2023 July 31, 2024
NCT04222413 Recruiting Phase 1 Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors October 27, 2020 December 31, 2027
NCT05938504 Recruiting N/A Usefulness of Balanced High Protein Supplementation on Recovery and Clinical Outcomes After Chemotherapy March 14, 2023 February 28, 2025
NCT04358328 Recruiting N/A Effect of CGA for Frail Elderly Patients Operated for Colorectal Cancer - The CRC Frailty-study October 1, 2020 August 31, 2025
NCT05944237 Recruiting Phase 1/Phase 2 HTL0039732 in Participants With Advanced Solid Tumours July 13, 2023 September 2026
NCT06403540 Recruiting The Impact of Laparotomy and Analgesia Methods on Diaphragm January 30, 2024 July 30, 2024
NCT04406974 Recruiting Locally Advanced Colorectal Cancer and Local Recurrences in Västra Götaland January 1, 2018 December 1, 2024
NCT05983133 Recruiting Phase 1 A Study of SGN-EGFRd2 in Advanced Solid Tumors November 14, 2023 September 30, 2028
NCT04457297 Recruiting Phase 3 Initial Attack on Latent Metastasis Using TAS-102 for ct DNA Identified Colorectal Cancer Patients After Curative Resection July 8, 2020 December 2023
NCT05988645 Recruiting N/A Performance and Safety of MiWEndo-assisted Colonoscopy (MiWEndo II) August 1, 2023 December 29, 2024
NCT01763125 Recruiting Establishment of a Tumor Bank for Blood Samples November 2003 December 2026
NCT01789229 Recruiting Establishment of a Tumor Bank for Tissue Samples September 2003 December 2026
NCT04755920 Recruiting Phase 2 SGM-101 in Colorectal Brain Metastases. January 1, 2024 February 2026
NCT04812912 Recruiting Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer March 18, 2021 March 18, 2025
NCT06076811 Recruiting DANISH.MRD: Danish Assessment of Minimal Residual Disease by Liquid Biopsies August 1, 2023 July 30, 2030
NCT06128798 Recruiting N/A Effect of Preoperative Immunonutrition Versus Standard Oral Nutrition in Patient Undergoing Colorectal Surgery. September 26, 2023 September 25, 2024
NCT04911517 Recruiting Phase 2 Neoadjuvant Chemoradiotherapy Plus Tislelizumab Followed by TME for LARC. June 1, 2021 December 2024
NCT06131840 Recruiting Phase 1 A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors November 20, 2023 March 31, 2030
NCT01915225 Recruiting Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer July 21, 2013
NCT04956640 Recruiting Phase 1/Phase 2 Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C) July 19, 2021 February 2026
NCT04976634 Recruiting Phase 2 Pembrolizumab Plus Lenvatinib in Combination With Belzutifan in Solid Tumors (MK-6482-016) August 18, 2021 March 22, 2027
NCT06203587 Recruiting N/A Clinical Study of GPA33-specific PET/CT for the Diagnosis of Colorectal Cancer December 1, 2023 December 1, 2024
NCT06206096 Recruiting Phase 2 PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRC May 26, 2021 December 2025
NCT02087475 Recruiting Phase 3 Perioperative FOLFIRI VS Adjuvant FOLFIRI in Resectable Advanced CRC Failed to Oxaliplatin January 2011 December 2024
NCT06206603 Recruiting Epigenetic Regulation of Colorectal Polyps and Cancer January 3, 2024 April 2026
NCT05045976 Recruiting N/A Efficacy of Web-based Self-management Support Intervention on Health Outcomes in Patients With Colorectal Cancer September 19, 2021 December 31, 2023
NCT05081687 Recruiting Phase 3 Brazilian Total Neoadjuvant Therapy Trial February 20, 2020 December 30, 2023
NCT05090215 Recruiting N/A Supervised Exercise for Post-surgery Colorectal Cancer Patients May 13, 2022 February 2024
NCT06226857 Recruiting Phase 3 Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer January 17, 2024 December 31, 2027
NCT02222844 Recruiting N/A Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers August 2014 December 2027
NCT05148494 Recruiting Phase 4 TES RCT Fleet Enema vs Oral Mechanical Bowel Prep March 16, 2022 October 1, 2024
NCT02246634 Recruiting N/A Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE) August 2014 December 2029
NCT05153746 Recruiting N/A Adenoma Detection Rate of 3D Colonoscopy February 10, 2022 July 31, 2025
NCT06305364 Recruiting N/A Predicting Adenomatous Polyps in the Colon Using Images of a Human Tongue August 1, 2023 December 1, 2024
NCT06314971 Recruiting Predicting Local and Distant Recurrence in T1 Colorectal Cancer March 15, 2023 March 15, 2025
NCT05185947 Recruiting Phase 2 Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer October 13, 2022 December 30, 2031
NCT05187481 Recruiting Phase 3 Effect of Jianpi Huatan Decoction on Advanced Colorectal Cancer November 15, 2021 July 2024
NCT05227014 Recruiting Enhanced Recovery and Patient Blood Management in Colorectal Surgery July 1, 2022 February 29, 2024
NCT05239741 Recruiting Phase 3 Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66) April 2, 2022 November 10, 2026
NCT05247346 Recruiting N/A Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo Measurements July 1, 2022 December 1, 2024
NCT05253651 Recruiting Phase 3 A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer October 24, 2022 April 30, 2028
NCT06324097 Recruiting Diagnostic Value of Endocytoscopy for Colorectal Lesions April 1, 2024 May 2024
NCT02484404 Recruiting Phase 1/Phase 2 Phase I/II Study of the Anti-Programmed Death Ligand-1 Durvalumab Antibody (MEDI4736) in Combination With Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Can... June 29, 2015 December 30, 2025
NCT06335654 Recruiting Real-time Artificial Intelligence-based Endocytoscopic Diagnosis of Colorectal Neoplasms April 1, 2024 December 31, 2024
NCT05286814 Recruiting Phase 2 M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma October 24, 2022 December 31, 2028
NCT05358249 Recruiting Phase 1/Phase 2 Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation October 24, 2022 June 16, 2027
NCT05372198 Recruiting Phase 2 Surufatinib With or Wothout Immunotherapy for Advanced Colorectal Cancer in Later Line March 30, 2022 December 2024
NCT06342401 Recruiting Early Onset Colorectal Cancer Detection April 15, 2023 October 15, 2025
NCT05381792 Recruiting Serial Gut Microbiome and Bacterial Gene Markers Changes After Endoscopic Resection of Colorectal Advanced Neoplasia September 1, 2022 December 15, 2024
NCT05391477 Recruiting N/A Artificial Intelligence for Diminutive Polyp Characterization February 27, 2023 December 2024
NCT02732860 Recruiting Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host December 2015 January 4, 2025
NCT05396560 Recruiting Fecal Immunochemical Test for Post-polypectomy Surveillance to Reduce Unnecessary eNdoscopy April 15, 2022 April 15, 2027
NCT05396846 Recruiting N/A My Best GI Eating Study June 13, 2023 September 2026
NCT02781337 Recruiting Epidemiological and Molecular Colorectal Cancer Registry May 2012 December 2033
NCT05401318 Recruiting Tailoring Treatment in Colorectal Cancer March 28, 2022 January 1, 2027
NCT04108481 Suspended Phase 1/Phase 2 Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer October 5, 2020 December 31, 2025
NCT03743428 Suspended N/A Biomarkers for Apatinib and Bevacizumab in Second-line Therapy for Colorectal Cancer(BABST-C) October 22, 2020 December 31, 2026
NCT03839277 Suspended N/A Adenoma Detection Rate Using Endocuff Vision in China June 12, 2019 December 1, 2020
NCT04276090 Terminated N/A Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma May 1, 2020 June 14, 2022
NCT03515824 Terminated Phase 1 Study of MK-1697 in Participants With Advanced Solid Tumors (MK-1697-001) August 13, 2018 February 18, 2020
NCT00145665 Terminated Phase 1/Phase 2 The Role of Fluorothymidine Positron Emission Tomography (FLT-PET) in Proliferation of Colorectal Liver Metastases January 2005 December 2012
NCT00403052 Terminated Phase 1 A Study of 1018 Immunostimulatory Sequence (ISS) Administered With Irinotecan and Cetuximab to Treat Patients With Previously Treated Metastatic Colorectal Cancer November 2006 December 2007
NCT00320320 Terminated Phase 2 Irinotecan Discontinuation and Reintroduction for Advanced Colorectal Cancer April 2005 April 2007
NCT04644315 Terminated Phase 2 A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors May 24, 2021 May 16, 2022
NCT04665921 Terminated Phase 1 A Study of SGN-STNV in Advanced Solid Tumors January 18, 2021 March 1, 2024
NCT01939223 Terminated Phase 3 Colorectal Cancer Treated With Adjuvant Regorafenib Versus Placebo After Curative Treatment of Liver Metastases in a Randomized, Double-blind, Placebo-Controlled Phase-III STudy December 2, 2013 August 29, 2016
NCT00051688 Terminated Phase 2 Tezacitabine and Oxaliplatin for the Treatment of Patients With Metastatic Colorectal Cancer June 2003 August 2004
NCT03219918 Terminated N/A Adenoma Detection Rate in Colonoscopy Performed With EndoRings June 19, 2017 June 7, 2018
NCT00385021 Terminated Phase 2 ChronoFOLFOX Plus Avastin for Patients With Metastatic Colorectal Cancer October 2006 September 2007
NCT00506168 Terminated Phase 2 Study of Irinotecan & Capecitabine in Metastatic Colorectal Cancer November 2001 July 2007
NCT03050814 Terminated Phase 2 Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004 April 5, 2017 August 25, 2021
NCT01336985 Terminated Phase 1 Safety and Pharmacokinetics of Treating Liver Cancer With Drug-Eluting Beads March 28, 2011 March 28, 2011
NCT01993472 Terminated Phase 2 Study of Andrographolides With or Without Capecitabine to Treat Colorectal Cancer November 2013 December 2016
NCT01765582 Terminated Phase 2 Sequential and Concurrent FOLFOXIRI/Bevacizumab Regimens Versus FOLFOX/Bevacizumab in First-Line Metastatic Colorectal Cancer January 23, 2013 March 14, 2016
NCT02175654 Terminated Phase 2 Regorafenib as Single Agent in Patients With Metastatic Colorectal Cancer (mCRC) With Any RAS or BRAF Mutation Previously Treated With FOLFOXIRI Plus Bevacizumab June 2014 February 2016
NCT03685591 Terminated Phase 1 PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors October 4, 2018 March 30, 2022
NCT05456165 Terminated Phase 2 Study of an Individualized Vaccine Targeting Neoantigens in Combination With Immune Checkpoint Blockade for Patients With Colon Cancer May 19, 2022 September 1, 2022
NCT00603577 Terminated Phase 3 Role of Xaliproden on Recovery Rate From Severe Neuropathy in Patients Who Have Completed Adjuvant Chemotherapy With Oxaliplatin Based Regimens January 2008 November 2009
NCT00609622 Terminated Phase 2 Randomized Study Of Sunitinib Plus FOLFOX Versus Bevacizumab Plus FOLFOX In Metastatic Colorectal Cancer April 2008 July 2011
NCT05099549 Terminated Phase 1/Phase 2 Safety, Tolerability, and Anti-Tumor Activity of AFM24 in Combination With SNK01 in Subjects With Advanced/Metastatic EGFR-Expressing Cancers November 3, 2021 September 21, 2023
NCT00398333 Terminated Phase 4 Study to Assess the Effectiveness of a Omega-3 Enriched Supplement on Chemotherapy Tolerance in Colon Cancer Patients June 2005 March 2008
NCT02014116 Terminated Phase 1 A Study of LY3009120 in Participants With Advanced Cancer or Cancer That Has Spread to Other Parts of Their Body November 26, 2013 October 5, 2018
NCT02952989 Terminated Phase 1 A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors February 23, 2017 June 24, 2019
NCT00314353 Terminated Phase 2 Study of Bevacizumab Combined With Capecitabine and Either Oxaliplatin or Irinotecan as First Course of Treatment for Patients With Colorectal Cancer That Has Spread Beyond the Colon March 2006 June 2010
NCT04104334 Terminated N/A Impact of an Optimised Monitored Anesthesia on the Patients' Recovery After Cytoreduction Surgery Plus HIPEC May 8, 2019 November 30, 2020
NCT01137162 Terminated Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors August 2008 October 2011
NCT00321100 Terminated Phase 2 Combination of Cetuximab, Capecitabine, and Oxaliplatin With or Without Bevacizumab April 12, 2006 December 18, 2013
NCT01134666 Terminated An Observational Study to Evaluate the Safety and Efficacy of FOLFIRI / FOLFOX Plus Cetuximab as First-line Therapy in Patients With KRAS Wild-type Metastatic Colorectal Cancer November 30, 2009 August 5, 2014
NCT00106054 Terminated Phase 2 Neoadjuvant Colorectal Cancer With Unresectable Liver Metastases January 2006 September 2006
NCT00976508 Terminated Phase 1 Figitumumab Combined With Pegvisomant For Advanced Solid Tumors November 2009 October 2012
NCT02559024 Terminated Phase 1 Anti-OX40 Antibody (MEDI6469) in Patients With Metastatic Colorectal Cancer March 14, 2016 October 2018
NCT02780700 Terminated Phase 2 Nintedanib Alone or in Combination With Capecitabine in Refractory Metastatic Colorectal Cancer [LUME-Colon 2] July 5, 2016 September 9, 2016
NCT00040391 Terminated Phase 2 A Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal Cancer June 2002
NCT04827485 Terminated N/A Gluteal Squeeze for Left Colon Distension January 13, 2022 April 11, 2022
NCT02425683 Terminated Phase 2 Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of Care (No Treatment) After Adjuvant FOLFOX March 26, 2015 September 21, 2017
NCT02866344 Terminated N/A Resection Versus Microwave Ablation for Resectable Colorectal Cancer Liver Metastases August 2016 February 2018
NCT00037180 Terminated Phase 2 For Prevention of Diarrhea in Patients Diagnosed With Metastatic Colorectal Cancer Treated With Chemotherapy April 2002 January 2003
NCT03189030 Terminated Phase 1 Study of Personalized Immunotherapy in Adults With Metastatic Colorectal Cancer May 2, 2017 September 2, 2020
NCT02439008 Terminated N/A Early Biomarkers of Tumor Response in High Dose Hypofractionated Radiotherapy Word Package 3 : Immune Response September 16, 2015 March 18, 2019
NCT04194034 Terminated Phase 1/Phase 2 Study of Intrahepatic Arterial Infusion of TG6002 in Combination With 5-FC in Patients With Metastatic Colorectal Cancer January 17, 2020 February 23, 2023
NCT00889343 Terminated Phase 2 Study to Evaluate the Effects of Sorafenib if Combined With Chemotherapy (FOLFOX6 or FOLFIRI) in the Second-Line Treatment of Colorectal Cancer March 2009 December 2012
NCT01098422 Terminated N/A A Study of Yttrium-90 Radioactive Resin Microspheres to Treat Colorectal Adenocarcinoma Metastatic to the Liver January 2010 February 2015
NCT02581709 Terminated N/A An Intervention Programme to Reduce Cognitive Impairment Due to Cancer May 2016 October 2017
NCT00065117 Terminated Phase 2 Safety, Tolerability and Efficacy of ZD6126 in Combination With Oxaliplatin, 5-Fluorouracil and Leucovorin in Subjects With Metastatic Colorectal Cancer. September 2003 February 2004
NCT01632020 Terminated Phase 2 Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth August 2012 January 2015
NCT02503631 Terminated Stool Sample Collection Protocol for Development of Screening Test for Colorectal Cancer and Other Digestive Tract Cancers October 2014 September 2017
NCT00036517 Terminated Phase 1/Phase 2 Safety Study of the Chemotherapy Modulator PHY906 in Patients With Advanced Colorectal Cancer February 2002 March 2003
NCT00041691 Terminated Phase 1 Safety Study of 90Y-hMN14 to Treat Colorectal Cancer Patients With Limited Residual Disease After Surgery
NCT00950820 Terminated Phase 2 Study to Evaluate the Effects of Panitumumab if Combined With Chemotherapy for 2nd Treatment of Colorectal Cancer September 2009 March 2012
NCT04515394 Terminated Phase 2 Study of Tepotinib Combined With Cetuximab in Participants With Left-Sided RAS/BRAF Wild Type Metastatic Colorectal Cancer (PERSPECTIVE) January 28, 2021 March 31, 2022
NCT02842580 Terminated Phase 2 De-escalation Chemotherapies Versus Escalation in Non Pre-treated Unresectable Patients With Metastatic Colorectal Cancer September 2016 October 2020
NCT03271255 Unknown status Phase 2 Apatinib Versus Bevacizumab in Second-line Therapy for Colorectal Cancer(ABST-C) May 23, 2018 December 31, 2022
NCT03412994 Unknown status Phase 2 Clinical Study of Apatinib Combined With Second - Line Chemotherapy for Metastatic Colorectal Cancer February 28, 2018 February 28, 2021
NCT03418948 Unknown status N/A Comparison of AMR and ADR Between Endocuff Vision-assisted and Conventional Colonoscopy: a Multicenter Randomized Trial December 8, 2017 November 1, 2019
NCT03242369 Unknown status N/A Comparison of the Effectiveness of Bowel Preparations Before Colonoscopy September 1, 2017 March 31, 2019
NCT05045911 Unknown status N/A An Endoscopic Barbed-clips Suturing for Colorectal ESD September 20, 2021 December 20, 2021
NCT03486418 Unknown status European Serrated Adenoma Classification Score April 1, 2018 April 2021
NCT03487939 Unknown status Phase 2 Neoadjuvant FOLFOXIRI Chemotherapy in Resectable Liver Metastasis of Colorectal Cancer May 1, 2018 October 1, 2021
NCT03511170 Unknown status Phase 2 XELOX and XELIRI Alternative Regimen as First-line Treatment for Advanced Colorectal Cancer March 1, 2018 June 1, 2020
NCT03511183 Unknown status Phase 2 XELOX+Bevacizumab and XELIRI + Bevacizumab Alternative Regimen as First-line Treatment for Advanced Colorectal Cancer March 1, 2018 June 1, 2020
NCT00220246 Unknown status Clinical and Molecular Characterization of Familial Microsatellite Stable Colorectal Cancer March 2004 September 2008
NCT00419627 Unknown status Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas February 2007
NCT03561350 Unknown status Detect Microsatellite Instability Status in Blood Sample of Advanced Colorectal Cancer Patients by Next-Generation Sequencing September 28, 2017 September 2018
NCT00454519 Unknown status Phase 2 Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy (IPHC) to Treat Peritoneal Carcinomatosis March 2007
NCT05066048 Unknown status Intestinal Microecological Dysregulation Caused by Appendectomy Increases the Risk of Colorectal Cancer April 30, 2021 January 31, 2024
NCT05069571 Unknown status Endoangel Withdrawal Overspeed Analysis March 1, 2020 February 1, 2022
NCT05349110 Unknown status Real-time Diagnosis of Diminutive Colorectal Polyps Using AI August 20, 2021 December 2022
NCT00507143 Unknown status N/A Study of Genetic Polymorphisms of Drug Transporters and Orphan Nuclear Receptors on Treatment Effects of Irinotecan August 2006 December 2008
NCT03604237 Unknown status N/A Targeted Forceps Biopsy for Colorectal Tumors September 1, 2017 October 1, 2018
NCT03612674 Unknown status N/A Adenoma Detection Rate With Endocuff-Assisted Colonoscopy - an Italian Trial April 4, 2018 August 2019
NCT03218423 Unknown status Longitudinal Performance of Epi proColon August 18, 2017 January 2024
NCT00081536 Unknown status Phase 1/Phase 2 Aroplatin and Capecitabine in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies
NCT03771456 Unknown status Anastomotic Leakage and Enhanced Recovery Pathways After Colorectal Surgery January 7, 2019 December 31, 2019
NCT00643877 Unknown status Phase 3 Trial of Preoperative Hepatic and Regional Arterial Chemotherapy (PHRAC) to Prevent Postoperative Liver Metastasis of Colorectal Cancer December 2008 December 2014
NCT00659022 Unknown status Phase 2 Neo-adjuvant Therapy and the Effect on Synchronous Metastatic Growth July 2008 April 2014
NCT03803891 Unknown status Endoscopic Full-Thickness Resection In Colon May 1, 2018 July 31, 2020
NCT00184782 Unknown status N/A Evaluation of Metabolic Activity of Liver Metastases by FDG-PET Scanning September 2003 December 2008
NCT05412355 Unknown status Effects of Incomplete ERAS on Clinical Outcomes in Patients With Colorectal Cancer June 1, 2022 October 10, 2022
NCT00765869 Unknown status N/A Randomised Controlled Trial of a Literacy Sensitive Decision Aid for Bowel Cancer Screening July 2008 February 2009
NCT03843905 Unknown status Predictive Value of Innovative Prognostic Markers (Gut Microbiota, Sarcopenia, Metabolic Syndrome and Obesity) on Surgical and Oncologic Results in the Management of Sporadic Colorectal Adenocarcinoma. November 15, 2018 November 15, 2021
NCT00813137 Unknown status Phase 2 FOLFOX4 Combined With Endostar in Patients With Advanced Colorectal Cancer October 2008 October 2010
NCT00839111 Unknown status Phase 2 Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment November 2008 November 2010
NCT02208804 Unknown status Phase 2/Phase 3 Surefire Infusion System vs. Standard Microcatheter Use During Holmium-166 Radioembolization November 2014
NCT02928120 Unknown status Diagnostic Potential of Hypermethylated DNA in Colorectal Cancer February 2015 September 2018
NCT00888797 Unknown status Phase 3 β-adrenergic Blocker and a COX2 Inhibitor for Prevention of Colorectal Cancer Recurrence January 2010 January 2017
NCT02528526 Unknown status Phase 1/Phase 2 Effects of OXY111A in Primary and Secondary Hepato-Pancreato-Biliary Neoplasm February 2014 December 2016
NCT00290524 Unknown status Phase 3 Early Alimentation Following Colorectal Surgery January 2006
NCT00057395 Unknown status Phase 1/Phase 2 A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Solid Malignancies
NCT00156975 Unknown status Phase 3 Oxaliplatin and Capecitabine Versus Follow-up After Resection of Colorectal Liver Metastases November 2004
NCT01112046 Unknown status Phase 3 Endoscopic Submucosal Dissection Versus Laparoscopic Resection for Early Colorectal Neoplasms April 2010 April 2015
NCT04148378 Unknown status A Pilot Study to Explore the Role of Gut Flora in Colorectal Cancer March 2, 2020 July 2023
NCT03070613 Unknown status Early Phase 1 Investigating the Use of Fluorescent Lectins to Identify Dysplasia and Cancer During Endoscopy and Surgery April 23, 2017 March 1, 2018
NCT05368051 Unknown status Multi-omics Model Predicts Efficacy of Preoperative Neoadjuvant Chemoradiotherapy Combined PD-1 Antibody Therapy for Locally Advanced Rectal Cancer October 1, 2021 October 31, 2022
NCT02829385 Unknown status Phase 2 Clinical Study of Apatinib and XELOX Combination Regimen to Treat Colorectal Cancer Patients June 2016 September 2018
NCT04230772 Unknown status N/A Clinical Outcomes of NOSES Versus Traditional Robotic-assisted Surgery for Patients With Colorectal Cancer February 1, 2021 December 31, 2022
NCT03042091 Unknown status Early Phase 1 Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery September 2016 October 2021
NCT04293315 Unknown status N/A Screening of Colorectal Cancer in the Public Healthcare Sector in Argentina June 9, 2018 March 15, 2020
NCT01428752 Unknown status Study of Prevalence of Colorectal Adenoma in 30- to 49-year-old Subjects With a Family History of Colorectal Cancer September 2011 September 2014
NCT01434199 Unknown status Phase 3 Does Endoscope Position Detecting Unit Facilitate a Complete Colonoscopy Examination July 2011 July 2012
NCT04302363 Unknown status Analysis of Intestinal Microflora Combined With DNA Methylation in Stool to Detect Colorectal Cancer February 1, 2018 December 1, 2021
NCT04326296 Unknown status Phase 1 The Safety and Tolerability of PD-L1 Monoclonal Antibody Plus Lenalidomide in The Treatment of Colorectal Cancer May 30, 2020 March 2023
NCT02368977 Unknown status N/A Third Eye Panoramic Device Feasibility Evaluation November 12, 2013 October 11, 2017
NCT02882659 Unknown status Phase 1 Dendritic Killer Cell-based Immunotherapy for Solid Tumors August 2014 December 2017
NCT05200611 Unknown status Fecal Immunochemical Test for Advanced Adenoma Detection in Colorectal Cancer Screening January 4, 2022 July 1, 2022
NCT01564810 Unknown status Phase 4 Cetuximab in Combination With Chemotherapy for the Treatment of Metastatic Colorectal Cancer September 2006 September 2015
NCT04397783 Unknown status N/A Longitudinal Incision Versus Cruciate Incision in the Construction of an End Colostomy April 15, 2019 April 15, 2022
NCT05203978 Unknown status Virtual Reality Colonoscopy : a Study From Nancy March 2022 June 2022
NCT04484311 Unknown status Non-curative ESDs: Assessing the Rates and Risk Factors for Residual Neoplasia August 1, 2020 December 2020
NCT02777814 Unknown status Phase 2 Prophylactic or Preemptive Entecavir in Patients With Colorectal Cancer Who Are Inactive Hepatitis B Carriers May 1, 2015 November 2019
NCT04516174 Unknown status N/A Effect of Transversus Abdominis Plane Block Combined With Dexmedetomidine Infusion on the Prognosis in Elderly Patients Undergoing Abdominal Surgery September 1, 2020 September 1, 2023
NCT04552093 Unknown status Phase 2/Phase 3 Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT) September 9, 2020 December 31, 2022
NCT04573088 Unknown status N/A Acceptance-based Intervention at Colorectal Cancer Patients June 22, 2020 January 20, 2022
NCT02999217 Unknown status Phase 4 Intravenous Iron for Correction of Anaemia After Colorectal Surgery October 2016 October 2018
NCT00141466 Unknown status N/A Implementation of a New Strategy to Identify HNPCC Patients September 2005 July 2007
NCT04684355 Unknown status N/A Quality of Life of Colorectal Cancer Screenees in the Period Between Colonoscopy and Next Clinic Visit for Final Report: Does Real-time Endoscopic Optical Diagnosis Improve Their Quality of Life December 22, 2020 December 30, 2021
NCT02450656 Unknown status Phase 1/Phase 2 Afatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer June 2015 December 2019
NCT05440565 Unknown status N/A Evaluation of Different Colorectal Cancer Screening Strategies July 2022 December 2023
NCT02657044 Unknown status N/A EMR Versus ESD for Resection of Large Distal Non-pedunculated Colorectal Adenomas April 2016 December 2020
NCT04749303 Unknown status N/A Impact of Screen Size on Colorectal Adenoma Detection July 1, 2020 August 31, 2021
NCT02672657 Unknown status Determinants of Quality Of Life in AGEd Cancer Patients February 2016 December 2019
NCT04831632 Unknown status Diagnostic Performance Assessment of Qualitative Ifobt and Quantitative Ifobt for Advanced Neoplastic May 1, 2021 December 31, 2022
NCT02781155 Unknown status Phase 1/Phase 2 Limiting Chemotherapy Side Effects by Using Moxa February 2016 September 2017
NCT02934958 Unknown status N/A FIT Mailing Protocol-For Cancer Screening Navigation October 2015 May 2017
NCT01880658 Unknown status Phase 2 Phase II Study of Maintenance Capecitabine to Treat Resectable Colorectal Cancer June 2013 May 2019
NCT01880918 Unknown status A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing October 2012 July 2013
NCT04878692 Unknown status N/A Evaluation of a Cosmetic Product to Preserve Skin Conditions When Using Anti-EGFR Cancer Therapies June 1, 2021 July 1, 2022
NCT02717923 Unknown status Phase 2 A Single Arm, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Maintenance Treatment With Capecitabine Plus Cetuximab in Metastatic Colorectal Cancer January 2014 June 2019
NCT02837679 Unknown status N/A Oncogeriatric Intervention and Follow-up at Home January 2016 January 2023
NCT04915833 Unknown status N/A Computer-aided Detection During Screening Colonoscopy (Experts) April 26, 2021 June 28, 2022
NCT02748772 Unknown status Phase 3 Application of Two Anti-angiogenesis Drugs Combined With Chemotherapy in Advanced Colorectal Cancer Under the Background of Precision Medical January 2016 December 2018
NCT01924897 Unknown status N/A Preop CPET Testing and Exercise Training in Colorectal Patients
NCT01930864 Unknown status Phase 2 Metformin Plus Irinotecan for Refractory Colorectal Cancer September 1, 2015 December 1, 2020
NCT01944540 Unknown status N/A Brief Title : Optimized Endoscopic Submucosal Dissection With Snaring for Colorectal Neoplasm August 2013
NCT05440552 Unknown status N/A Evaluation of Colorectal Cancer Screening Strategies in China July 2022 December 2023
NCT01972503 Unknown status Phase 4 Intraoperative Intraportal Chemotherapy Combined With Adjuvant Chemotherapy for Stage II and III Colorectal Cancer June 2008 September 2015
NCT05292417 Unknown status Phase 2 Radiotherapy in Combination With Sintilimab，GM-CSF and Fruquintinib in Patients With MSS mCRC March 25, 2022 March 2024
NCT01995942 Unknown status Molecular, Pathologic and MRI Investigation of the Prognostic and Redictive Importance of Extramural Venous Invasion in Rectal Cancer (MARVEL) Trial June 7, 2013 February 2, 2022
NCT05322486 Unknown status Palliative Primary Tumor Resection in Minimally Symptomatic Patients With Colorectal Cancer and Synchronous Unresectable Metastases October 29, 2020 December 2022
NCT02005965 Unknown status Low Rectal Cancer Study (MERCURY II) August 13, 2007 March 11, 2021
NCT02027363 Unknown status Phase 2 Maintenance Treatment With Capecitabine in Colorectal Cancer Patients January 2010 June 2014
NCT04996355 Unknown status Organoids-on-a-chip for Colorectal Cancer and in Vitro Screening of Chemotherapeutic Drugs May 31, 2021 May 30, 2024
NCT02495532 Unknown status N/A Clinical Trial Comparing Carnoy's and GEWF Solutions for Lymph Node Clearing Technique in Colorectal Cancer March 2015 March 2018
NCT02066688 Unknown status Phase 2/Phase 3 Study of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer January 2013 December 2017
NCT03303495 Unknown status Phase 3 A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC November 14, 2011 December 31, 2018
NCT00043199 Unknown status Phase 2 A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies
NCT02552017 Unknown status N/A Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities November 2014 June 2016
NCT02556281 Unknown status N/A Prognostic Value of Circulating Tumoral Free DNA Versus Circulating Tumoral Cells in Patients With Colorectal Cancer Stage II-III October 15, 2012 September 2019
NCT01037049 Unknown status Phase 2 Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks October 16, 2009 December 8, 2019
NCT02316535 Unknown status Phase 3 Low-dose Capecitabine Adjuvant Chemotherapy for Elderly Patients With Stage II/III Colorectal Cancer November 2014 May 2018
NCT05158374 Unknown status N/A Molecular Effects of Aspirin & Metformin on Colonic Epithelium August 2022 June 2023
NCT05170360 Unknown status Evaluation of Some Risk Factors Associated With Colorectal Cancer December 2021 December 2023
NCT02504411 Withdrawn N/A Outcomes of Disposable Distal Attachment Device (Endocuff and Transparent Plastic Cap) Assisted Colonoscopy August 2015 February 15, 2017
NCT04192929 Withdrawn N/A Chromoendoscopy or Narrow Band Imaging (NBI) for Improving Adenoma Detection in Colonoscopy September 2023 February 2025
NCT00718055 Withdrawn Magnetic Resonance Imaging (MRI) Using Liverspecific Oral Contrast Agent in Metastatic Colorectal Cancer Patients November 2006
NCT00035919 Withdrawn Phase 1/Phase 2 Safety and Efficacy of Targeted Gene Transfer in Colorectal Cancer Metastatic to Liver November 2002 October 2003
NCT05582031 Withdrawn Phase 2 Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers April 30, 2023 April 30, 2025
NCT03191487 Withdrawn N/A Evaluation of a New Organization for Collecting Pre-chemotherapy Session Information April 2018 November 2019
NCT03843853 Withdrawn Phase 2 Pemetrexed and S-1 in Combination With Bevacizumab in Refractory Colorectal Cancer May 1, 2019 May 1, 2022
NCT00780988 Withdrawn Phase 1 Feasibility of Autologous Tumor Cell-TLR9 Agonist Vaccination for Metastatic Colorectal Cancer
NCT00988897 Withdrawn Phase 2 Colorectal Cancer RECHALLENGE October 2009 May 2012
MeSH unique ID (MeSH (Medical Subject Headings))
D015179