Adrenomyeloneuropathy

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Information
Disease name
Adrenomyeloneuropathy
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02699190 Active, not recruiting LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies January 6, 2017 December 2024
NCT04303416 Completed Phase 2/Phase 3 Plasma Exchange With Albumin in AMN Patients March 9, 2020 September 13, 2021
NCT01495260 Completed Phase 2 A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants September 2011 November 2013
NCT03627416 Completed N/A Repetitive Transcranial Magnetic Stimulation as Therapy in Hereditary Spastic Paraplegia and Adrenomyeloneuropathy January 9, 2017 January 1, 2019
NCT03864523 Completed Phase 2 Effect of Pioglitazone Administered to Patients With Adrenomyeloneuropathy January 2016 July 2019
NCT02961803 Completed Phase 2/Phase 3 MD1003-AMN MD1003 in Adrenomyeloneuropathy October 2014 June 2017
NCT01165060 Completed N/A The Effect of Bezafibrate on the Level of Very Long Chain Fatty Acids (VLCFA) in X-linked Adrenoleukodystrophy (X-ALD) July 2010 August 2011
NCT05146284 Not yet recruiting Phase 2 Study to Assess PXL770 in Subjects With Adrenomyeloneuropathy (AMN) Form of X-linked Adrenoleukodystrophy (X-ALD or ALD) September 2023 September 2024
NCT05443906 Recruiting N/A Home Exercise for Individuals With Neurodegenerative Disease February 13, 2023 July 30, 2027
NCT03047369 Recruiting The Myelin Disorders Biorepository Project December 8, 2016 December 8, 2030
NCT04925349 Recruiting Modeling Macrophages Activation Pattern in X-linked Adrenoleukodystrophy, Metachromatic Leukodystrophy and Adult Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia August 30, 2021 February 2025
NCT00545597 Terminated Phase 3 A Phase III Trial of Lorenzo's Oil in Adrenomyeloneuropathy March 2005 October 2007
NCT01787578 Withdrawn Phase 1 Safety and Pharmacodynamic Study of Sobetirome in X-Linked Adrenoleukodystrophy (X-ALD) April 2013 February 2014
OrphaNumber from OrphaNet (Orphanet)
139399