silicosis

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Information
Disease name
silicosis
Disease ID
DOID:10325
Description
"A pneumoconiosis that is an inflammation and scarring of the upper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles." [url:http\://en.wikipedia.org/wiki/Silicosis] {comment="ls:IEDB"}
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00005280 Completed Specialized Center of Research in Occupational and Immunologic Lung Disease June 1972 November 1991
NCT01725971 Completed Oscillation Mechanics of the Respiratory System in Never-smoking Patients With Silicosis July 2010 June 2013
NCT01977131 Completed Phase 1/Phase 2 Safety Study of Autologous Bone Marrow Stromal Cells With Modification by Hepatocyte Growth Factor to Treat Silicosis June 2010 September 2013
NCT02430259 Completed Phase 3 Efficacy of Weekly Rifapentine and Isoniazid for Tuberculosis Prevention March 2015 June 2018
NCT02794701 Completed Comprehensive Risk Assessment of People With Silicosis: A Population-based Study June 2016 April 2017
NCT04205708 Completed Screening Strategy for Early Diagnosis of Silicosis in At-Risk Populations in Oklahoma January 14, 2019 June 10, 2022
NCT06011785 Not yet recruiting Early Phase 1 Using Silica 12CH to Mitigate the Effects and Symptoms of Silicosis in Brazil March 1, 2024 March 1, 2026
NCT05402176 Not yet recruiting The SHIELD Whole Lung Lavage Study June 2022 December 2024
NCT06403800 Recruiting Silicosis and Silicotuberculosis Among Small Scale Gemstone Miners in Northern Tanzania March 11, 2024 December 1, 2025
NCT06090370 Recruiting N/A Reducing Silica Exposure Among Brick Kiln Workers in Nepal January 24, 2024 December 31, 2024
NCT04161014 Recruiting Phase 2 The Nintedanib in Progressive Pneumoconiosis Study (NiPPS): a Collaborative NSW Treatment Trial October 9, 2020 February 2025
NCT05538299 Recruiting Silicosis Treatment, Action, Screening and Surveillance in Rwanda Trials July 31, 2022 July 31, 2023
NCT05546944 Recruiting The SHIELD Study-silicosis August 16, 2022 December 2024
NCT05118256 Unknown status Phase 2 Pirfenidone for the Reduction of Metabolic, Inflammatory and Fibrogenic Activity in Complicated Silicosis November 15, 2021 November 15, 2023
NCT01329003 Unknown status DNA-damage Pathways in Workers Exposed to Silica (Caesar Stone) September 2011 September 2013
NCT01338064 Unknown status Oxidative Stress Biomarkers to Monitor and Early Detect Health Impairment in Workers Exposed to Silica (Caesar Stone) September 2011 September 2013
Disase is a (Disease Ontology)
DOID:10316
Cross Reference ID (Disease Ontology)
GARD:7647
Cross Reference ID (Disease Ontology)
ICD10CM:J62.8
Cross Reference ID (Disease Ontology)
ICD9CM:502
Cross Reference ID (Disease Ontology)
MESH:D012829
Cross Reference ID (Disease Ontology)
NCI:C3369
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:155590008
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0037116
Exact Synonym (Disease Ontology)
Pneumoconiosis due to silicates
Exact Synonym (Disease Ontology)
Silica pneumoconiosis
Exact Synonym (Disease Ontology)
Silicotic fibrosis of lung
Exact Synonym (Disease Ontology)
silicotuberculosis
MeSH unique ID (MeSH (Medical Subject Headings))
D012829