pre-eclampsia
Information
- Disease name
- pre-eclampsia
- Disease ID
- DOID:10591
- Description
- "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy." [url:http\://en.wikipedia.org/wiki/Pre-eclampsia, url:http\://ghr.nlm.nih.gov/condition/preeclampsia, url:https\://www.ncbi.nlm.nih.gov/pubmed/24400024]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06359015 | Active, not recruiting | Phase 4 | Metformin and Esomeprazole in Preterm Pre-eclampsia | February 11, 2021 | June 2025 |
| NCT04170660 | Active, not recruiting | Interest of sFlt1/PlGF Ratio at Obstetric Emergencies | November 18, 2019 | December 2023 | |
| NCT04484766 | Active, not recruiting | Preeclampsia Associated Vascular Aging | September 1, 2019 | June 30, 2023 | |
| NCT04273854 | Active, not recruiting | N/A | Physician Optimised Post-partum Hypertension Treatment Trial | February 21, 2020 | December 1, 2030 |
| NCT04580927 | Active, not recruiting | N/A | Breastfeeding and Postpartum Cardiovascular Health | March 15, 2021 | November 2025 |
| NCT03949829 | Active, not recruiting | The CoPenHagen PREeClampsia and cardIOvascUlar diSease Study | May 20, 2019 | June 30, 2031 | |
| NCT03018132 | Active, not recruiting | N/A | Preeclampsia Research on Vitamin D, Inflammation, & Depression | April 1, 2017 | July 2025 |
| NCT04514276 | Active, not recruiting | N/A | Inter- and Multidisciplinary, Cross-sectoral Feto-neonatal Pathway | June 1, 2020 | March 31, 2024 |
| NCT00158743 | Completed | Phase 2 | Efficacy Study of Digibind for Treatment of Severe Preeclampsia | February 2004 | December 2007 |
| NCT00175695 | Completed | Disease Modification in Toxaemia of Pregnancy | December 2004 | October 2010 | |
| NCT00197340 | Completed | Phase 3 | Antepartum Chronic Epidural Therapy (ACET) to Improve Blood Flow to the Uterus, Placenta and Baby in Pre-Eclampsia and Intrauterine Growth Restriction | August 2003 | December 2006 |
| NCT06224946 | Completed | IMPACT OF THE BIOLOGICAL RATIO ON MEDICAL DECISION MAKING IN WOMEN SUSPECTED OF PREECLAMPSIA | October 1, 2019 | January 27, 2021 | |
| NCT06214702 | Completed | Serpin C and Soluble Fms-like Tyrosine Kinase-1 Levels in Normotensive Pregnant Women May Predict the Development of Preeclampsia | January 7, 2023 | November 15, 2023 | |
| NCT00275158 | Completed | N/A | Glomerular Injury of Preeclampsia | January 2000 | December 2003 |
| NCT00303173 | Completed | N/A | The Relaxation and Blood Pressure in Pregnancy (REBIP) Study | August 2004 | February 2007 |
| NCT05924061 | Completed | The Role of Pentraxin 3 and Cathepsin B Levels in Preeclamptic Pregnancy | January 1, 2022 | December 31, 2022 | |
| NCT00438542 | Completed | HMW-Adiponectin is Raised in Newborns | July 2003 | July 2006 | |
| NCT00465634 | Completed | Doppler and Biological Second Trimester Placental Insufficiency Screening | May 2003 | June 2007 | |
| NCT05816044 | Completed | Evaluation of HALP Score in Preeclampsia | February 22, 2023 | July 15, 2023 | |
| NCT00485784 | Completed | N/A | Interest of Circulating Endothelial Biomarkers in Vascular Pregnancy Complications | July 2007 | |
| NCT05709834 | Completed | N/A | Autogenic Training Effects on Pre-eclampsia | January 15, 2022 | March 15, 2023 |
| NCT05703802 | Completed | Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia. | February 1, 2022 | November 1, 2022 | |
| NCT05542654 | Completed | N/A | The Effect of Foot Massage on Blood Pressure and Anxiety Levels in Pregnants With Hypertension | November 5, 2020 | February 15, 2022 |
| NCT00930397 | Completed | Observational Study in UTERO - Placental 3D Doppler Examination: Interest for Pre-eclampsia Screening During Pregnancy | July 2009 | November 2011 | |
| NCT05470712 | Completed | Vital Mechanism of NETs Formation vs. Suicidal Mechanism of NETs Formation During Normal Pregnancy and Preeclampsia | July 20, 2022 | December 31, 2022 | |
| NCT01278459 | Completed | Phase 3 | Can Atorvastatin Improve Vascular Function in Women With a History of Preeclampsia? | October 2011 | April 2012 |
| NCT05299229 | Completed | Continuous Non-invasive Hemodynamic Monitoring in Early-onset Severe Preeclampsia: a Comparison of Echocardiography, Bioreactance, and Finger Cuff Measurements | December 29, 2020 | December 31, 2021 | |
| NCT01351428 | Completed | N/A | Goal-Directed Therapy in Pregnant Women at High Risk of Developing Preeclampsia | December 2010 | November 2012 |
| NCT01352234 | Completed | Phase 4 | Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia | September 2011 | March 2015 |
| NCT01395342 | Completed | Phase 1 | Assessment of Physical Exercise Using Stationary Bicycle for Pregnant Women With Risk for Preeclampsia Development | January 2008 | November 2011 |
| NCT01480544 | Completed | N/A | Improving Maternal and Child Health in India: Evaluating Demand and Supply Side Strategies (IMATCHINE) | August 2012 | November 2015 |
| NCT01490489 | Completed | N/A | EG-VEGF : Potential Marker of Pre-eclampsia and / or Intrauterine Growth Restriction | July 11, 2011 | March 13, 2015 |
| NCT05142410 | Completed | Understanding Post-translational Modifications to Circulating Histones Via Mass Spectrometry in Pregnant Women Developing Pre-eclampsia: A Retrospective Study | March 1, 2019 | December 1, 2023 | |
| NCT05098691 | Completed | Early Onset Preeclampsia and Nectin-4 | May 1, 2020 | December 30, 2020 | |
| NCT01606774 | Completed | N/A | A Modernized Approach to Prenatal Care in Low Risk Women | July 2012 | April 2014 |
| NCT04900207 | Completed | Placental Volume, Flow, and Vascularity Study | March 10, 2021 | June 30, 2022 | |
| NCT01669525 | Completed | Placental Growth and Adverse Pregnancy Outcomes | November 2009 | June 2016 | |
| NCT01729468 | Completed | Phase 4 | Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers | June 27, 2012 | October 25, 2016 |
| NCT01736826 | Completed | Free DNA and Nucleosome Concentrations in Pathological Pregnancies | June 2015 | December 17, 2018 | |
| NCT01801410 | Completed | Phase 3 | Induction With Foley OR Misoprostol (INFORM) Study | December 2013 | June 2015 |
| NCT01846156 | Completed | Phase 3 | New Magnesium Sulphate Protocol for Pre-eclampsia | May 2013 | April 2014 |
| NCT04864249 | Completed | N/A | Neonatal Sleep Intervention to Improve Postpartum Hypertension | July 9, 2021 | September 30, 2022 |
| NCT01911494 | Completed | N/A | Community Level Interventions for Pre-eclampsia | September 2013 | June 2018 |
| NCT04795154 | Completed | N/A | Prenatal Yoga as Complementary Therapy of Preeclampsia | September 2, 2020 | December 22, 2020 |
| NCT04683094 | Completed | Comparative Study for the Validity of Various Severity Scoring System | April 1, 2020 | December 30, 2021 | |
| NCT02050529 | Completed | Phase 2 | Randomized Controlled Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients. | October 2012 | March 2015 |
| NCT04633551 | Completed | N/A | Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes | October 1, 2020 | May 30, 2022 |
| NCT02214186 | Completed | N/A | Restrictive Fluid Therapy in Severe Preeclampsia | January 2014 | May 2015 |
| NCT02218931 | Completed | N/A | ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes | September 12, 2014 | April 30, 2017 |
| NCT02296931 | Completed | Phase 1/Phase 2 | Assessment of a Syringe Pump to Pre-eclamptic Women in a Low-resource Hospital | March 2015 | October 3, 2017 |
| NCT02333240 | Completed | N/A | Self-management of Postnatal Anti-hypertensive Treatment: a Trial Development Pilot Study | April 2015 | November 2016 |
| NCT02338687 | Completed | Phase 4 | Low Dose Calcium to Prevent Preeclampsia | October 2014 | October 2018 |
| NCT00000543 | Completed | Phase 2 | Oral Calcium in Pregnant Women With Hypertension | August 1993 | July 1999 |
| NCT02357264 | Completed | Thoracic Ultrasonography for Pulmonary Edema in Patients With Pre-Eclampsia | February 2015 | January 2017 | |
| NCT04615624 | Completed | Phase 3 | Furosemide vs. Placebo for Severe Antepartum Hypertension | January 4, 2021 | April 29, 2022 |
| NCT02443259 | Completed | Neurobehavioural Outcomes in Late Preterm Neonates | January 2014 | October 2015 | |
| NCT02468310 | Completed | N/A | Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana | August 10, 2015 | April 9, 2017 |
| NCT02677233 | Completed | Association Between Vitamin D Deficiency and Preeclampsia: A Case Control Study | June 2015 | January 2016 | |
| NCT04455204 | Completed | Adipokines, Inflammation, Insulin Resistance and Endothelial Dysfunction in Preeclampsia | April 25, 2016 | October 1, 2019 | |
| NCT02721771 | Completed | Acid-Base and Point of Care Ultrasound in Severe Preeclampsia | March 2016 | October 2016 | |
| NCT02801695 | Completed | Phase 2/Phase 3 | Evaluation of the Efficacy of Citrulline Supplementation on the Delay of Delivery for Women Hospitalized for Pre-eclampsia (CITRUPE) | February 20, 2017 | December 1, 2020 |
| NCT04374604 | Completed | Placental Growth Factor as a Predictor of Adverse Pregnancy Outcomes in Preeclamptic Women | October 1, 2018 | July 31, 2019 | |
| NCT02881073 | Completed | N/A | Placental Growth Factor Assessment of Women With Suspected Pre-eclampsia | June 29, 2017 | April 26, 2019 |
| NCT02891174 | Completed | Phase 4 | The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy | December 1, 2016 | June 20, 2018 |
| NCT02911701 | Completed | Phase 4 | Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features | September 2016 | January 10, 2018 |
| NCT04367519 | Completed | Optic Nerve Sheath Diameter for Volume Status Prediction in Severe Preeclampsia | October 1, 2019 | April 15, 2020 | |
| NCT02992145 | Completed | Androgens Level in the Third Trimester of Pregnancy in Patients With Preeclampsia | March 2016 | December 2016 | |
| NCT03028194 | Completed | N/A | Postpartum Uterine Curettage in the Recovery From Preeclampsia/Eclampsia | October 1, 2015 | December 11, 2016 |
| NCT03073317 | Completed | N/A | PREPARE, Prematurity Reduction by Pre-eclampsia Care | December 1, 2016 | June 20, 2020 |
| NCT03101150 | Completed | Phase 1/Phase 2 | Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia | October 1, 2012 | December 31, 2015 |
| NCT04239352 | Completed | Preeclamptic Patients and Pentraxin 3 & Lipoprotein-associated Phospholipase A2 | January 20, 2020 | May 20, 2020 | |
| NCT03127865 | Completed | Evaluation of Electrical Velocimetry for Assessment of Extra-vascular Lung Water in Pre-eclamptic Patients | April 18, 2017 | August 16, 2017 | |
| NCT03151070 | Completed | Scaling Up an Integrated Approach to Improve Delivery Care in North Guatemala With Stepped Wedge Design | December 15, 2013 | March 15, 2017 | |
| NCT04204018 | Completed | N/A | Measuring Practice Pattern Changes and Clinical Utility of a Novel Test for Preeclampsia | November 22, 2019 | December 23, 2019 |
| NCT04037683 | Completed | qMOLI- A Qualitative Assessment of Misoprostol or Oxytocin for Labour Induction | October 18, 2019 | December 31, 2021 | |
| NCT04004897 | Completed | N/A | Optic Nerve Sheath Diameter in Preeclampsia | July 5, 2019 | November 25, 2019 |
| NCT03993145 | Completed | N/A | Lifestyle Intervention for Women With Recent Pre-eclampsia or Gestational Diabetes Mellitus ('Mom's Healthy Heart') | February 7, 2020 | May 4, 2021 |
| NCT03232762 | Completed | N/A | Effects of Diet on Pregnancy Outcome and Child Obesity | October 3, 2017 | August 22, 2019 |
| NCT03981029 | Completed | FACT Biomarker Subgroup Analysis | December 19, 2011 | September 2016 | |
| NCT03252496 | Completed | N/A | Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery | August 19, 2017 | July 15, 2021 |
| NCT00000534 | Completed | Phase 3 | Calcium for Pre-Eclampsia Prevention (CPEP) | March 1991 | June 2000 |
| NCT03978429 | Completed | N/A | An mHealth Strategy to Reduce Pre-Eclampsia and Infant Death in Tanzania | August 31, 2019 | July 1, 2020 |
| NCT03968952 | Completed | N/A | SMARThealth Pregnancy: Feasibility & Acceptability of a Complex Intervention for High-risk Pregnant Women in Rural India. | October 1, 2019 | November 1, 2020 |
| NCT03961360 | Completed | Phase 2/Phase 3 | Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese Gravida | May 6, 2019 | April 10, 2023 |
| NCT03316430 | Completed | Podocyturia as Predictive Factor for Pre-eclampsia | May 15, 2019 | December 7, 2021 | |
| NCT03330301 | Completed | D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life | April 1, 2012 | September 30, 2016 | |
| NCT03334149 | Completed | N/A | Blood Pressure Monitoring in High Risk Pregnancy to Improve the Detection and Monitoring of Hypertension | November 22, 2017 | September 16, 2020 |
| NCT03342014 | Completed | N/A | First Trimester Screening for Preeclampsia and Intrauterine Growth RestrIction Using Three Dimensional Doppler Angiography | April 16, 2018 | November 14, 2022 |
| NCT03941886 | Completed | N/A | Implementation of First-trimester Screening and preventiOn of pREeClAmpSia Trial (FORECAST) | July 31, 2019 | August 15, 2023 |
| NCT03356106 | Completed | N/A | Screening and Treatment of Obstructive Sleep Apnea in High-risk Pregnancy | November 16, 2016 | December 31, 2019 |
| NCT03391609 | Completed | Phase 2/Phase 3 | Peri-operative Dexmedetomidine Infusion in Pre-eclamptic Patients | June 18, 2017 | January 1, 2019 |
| NCT03419364 | Completed | Phase 2 | Study of Nicotinamide in Early Onset Preeclampsia | November 1, 2017 | August 31, 2021 |
| NCT03455387 | Completed | Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascular Pathologies in the 3rd Quarter of the Pregnancy. | January 10, 2017 | December 31, 2019 | |
| NCT03831490 | Completed | Study for Improving Maternal, Pregnancy and Child Outcomes | November 9, 2018 | December 31, 2022 | |
| NCT03509805 | Completed | N/A | Sleep Apnea Syndrome in Obese Women During Pregnancy | September 1, 2010 | March 14, 2017 |
| NCT03515759 | Completed | Fetal Doppler Indices in Predicting Perinatal Outcome Among Severely Hypertensive Pregnant Patients. | November 1, 2017 | January 15, 2019 | |
| NCT03554681 | Completed | Prediction of Preeclampsia (PE) at 11-13 Week | December 2016 | September 2019 | |
| NCT03755843 | Completed | PREDICTION OF FLUID RESPONSIVENESS WITH PASSIVE LEG RISING IN PREGNANT PATIENTS WITH SEVERE PREECLAMPSIA | December 1, 2016 | May 15, 2018 | |
| NCT03750695 | Completed | N/A | Acute Exercise Effects in Obese Pregnancy | November 20, 2018 | March 31, 2020 |
| NCT03749044 | Completed | N/A | ASA Patterns for Prevention of Preeclampsia in SLE Pregnancies | May 28, 2018 | March 11, 2024 |
| NCT03741179 | Completed | Phase 3 | Detection of False Positives From First-trimester Preeclampsia Screening (StopPRE) at the Second-trimester of Pregnancy | August 20, 2019 | January 30, 2022 |
| NCT03665623 | Completed | Prediction of Preeclampsia by Comprehensive Markers. | December 1, 2017 | August 31, 2020 | |
| NCT03650790 | Completed | N/A | C1q/TNF-related Protein 9 (CTRP 9) Level in Preeclamptic Obese and Non-obese Pregnancies | September 3, 2018 | January 1, 2019 |
| NCT03674606 | Completed | Phase 4 | Trial of Early Screening Test for Pre-eclampsia and Growth Restriction | February 1, 2014 | April 13, 2016 |
| NCT00004399 | Completed | N/A | Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia | September 1995 | August 2000 |
| NCT00005207 | Completed | Renin and Prorenin in Pregnancy | September 1987 | July 1992 | |
| NCT00005400 | Completed | Angiotensinogen Variants and Adverse Pregnancy Outcomes | August 1995 | July 2003 | |
| NCT00005456 | Completed | Hypertensive and Normal Pregnancy--Calcium Metabolism and Renin-Angiotensin - SCOR in Hypertension | December 1990 | November 1995 | |
| NCT06329284 | Completed | N/A | Midkine Role With Deregulated Oxidative and Immune Milieu in Induction of Preeclampsia | January 1, 2023 | December 15, 2023 |
| NCT00157521 | Completed | Phase 3 | L-Arginine in Pre-Eclampsia | September 2002 | May 2006 |
| NCT03269110 | Enrolling by invitation | Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child) | July 1, 2017 | July 31, 2024 | |
| NCT02347540 | Enrolling by invitation | Heart Failure and Related Risk-factors After Preeclampsia | December 2014 | July 2025 | |
| NCT04762992 | Enrolling by invitation | Phase 3 | LMWH for Treatment of Early Fetal Growth Restriction (HepaGrowth) | July 6, 2023 | July 30, 2025 |
| NCT05294952 | Not yet recruiting | Phase 4 | co Ihibtory Receptor in Preeclampsia | January 1, 2025 | November 4, 2025 |
| NCT06315985 | Not yet recruiting | N/A | Classical Turkish Music for Pregnant Women With Preeclampsia | March 20, 2024 | March 20, 2025 |
| NCT05188066 | Not yet recruiting | Study of Pregnancy Pathologies Associated With Placental Abnormalities | January 6, 2022 | January 31, 2030 | |
| NCT04979312 | Not yet recruiting | Glucose and Blood Pressure During Pregnancy | July 2024 | January 2025 | |
| NCT06122220 | Not yet recruiting | N/A | Optic Nerve Sheath Measurement and Angiogenic Factors in Patients With Pre-eclampsia. | May 1, 2024 | September 30, 2024 |
| NCT06452498 | Not yet recruiting | Phase 3 | Preeclampsia Intervention Netherlands | August 2024 | July 2028 |
| NCT04424693 | Not yet recruiting | Phase 4 | Comparing the Incidence of Preeclampsia Between Pregnant Women Receiving Tdap Vaccinations at Week 28 or at Week 36 | December 1, 2020 | December 31, 2024 |
| NCT06387784 | Not yet recruiting | N/A | Acute Beetroot Juice Supplementation in Pre-eclampsia Pregnancies | June 2024 | June 2025 |
| NCT06319014 | Not yet recruiting | N/A | Physical Activity to Mitigate PreEclampsia Risk | March 31, 2024 | October 1, 2026 |
| NCT06107335 | Not yet recruiting | Phase 4 | Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia | July 1, 2024 | July 1, 2025 |
| NCT06020378 | Not yet recruiting | Hydroxychloroquine May be Beneficial for Preeclampsia | December 1, 2023 | December 1, 2024 | |
| NCT05625763 | Not yet recruiting | State of Coagulation in Pre-eclampsia: Comparing Sonoclot Signature Analysis With Conventional and Specific Haemostasis Assays | November 15, 2022 | December 29, 2024 | |
| NCT06437535 | Not yet recruiting | Role of Vaspin in Pathophysiology of Pre-eclampsia | June 2024 | August 2025 | |
| NCT05622838 | Not yet recruiting | Maternal alpha1 Antitrypsin as a Marker of Intrauterine Growth Restriction in Pre-eclamptic Women | December 2022 | January 2025 | |
| NCT05533996 | Not yet recruiting | N/A | Body Fat Index for Obstetric Risk Stratification | March 1, 2023 | June 1, 2024 |
| NCT05746793 | Recruiting | At High-risk for Pre-eclampsia After Assisted Reproductive Technology | February 15, 2023 | October 1, 2027 | |
| NCT03626233 | Recruiting | Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection | August 6, 2018 | April 2024 | |
| NCT03806283 | Recruiting | Mechanisms of Pregnancy Vascular Adaptations | November 20, 2018 | April 2027 | |
| NCT03509272 | Recruiting | N/A | LimPrOn: Limburg Pre-eclampsia Investigation | May 2016 | December 2030 |
| NCT03893630 | Recruiting | Phase 2 | Role of ASpirin in Placental and Maternal Endothelial Cell Regulation IN Pre-eclampsia | April 25, 2019 | December 2023 |
| NCT03316391 | Recruiting | Association Between Pococyturia and Pre-eclampsia Severity | May 22, 2019 | September 22, 2026 | |
| NCT03298802 | Recruiting | Phase 3 | Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide | November 21, 2017 | August 30, 2024 |
| NCT04021680 | Recruiting | Clinical Effectiveness of First Trimester Pre-eclampsia Screening Program. | June 10, 2019 | June 20, 2025 | |
| NCT04356326 | Recruiting | Phase 3 | Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy | February 15, 2021 | February 2030 |
| NCT04389099 | Recruiting | MRI Angiography of Physiological and Pathological Pregnancy Placentas Ex-vivo | November 18, 2019 | November 17, 2024 | |
| NCT04463940 | Recruiting | Xanthine Oxidase and Uric Acid Origin in Preeclamptic Women | June 30, 2020 | August 2024 | |
| NCT04520048 | Recruiting | N/A | Vascular Biomarkers Predictive of the Progression From Gestational Hypertension to Preeclampsia in Pregnant Women | August 11, 2023 | December 2026 |
| NCT04551807 | Recruiting | Phase 3 | Natural Versus Programmed Frozen Embryo Transfer (NatPro) | September 16, 2020 | August 31, 2025 |
| NCT04676295 | Recruiting | N/A | Pre-eclampsia and Future Cardiovascular Health: An Underused Opportunity to Improve Family Health | June 1, 2019 | December 2024 |
| NCT04716244 | Recruiting | Development of Intervention for Women After Gestational Diabetes or Pre-eclampsia | January 20, 2021 | July 31, 2025 | |
| NCT04783597 | Recruiting | Early Prediction of Preeclampsia Using arteriaL Stiffness in High-risk prEgnancies | July 12, 2021 | April 2025 | |
| NCT05056467 | Recruiting | N/A | Labor Induction in Preeclampsia High-risk Women | January 1, 2022 | December 31, 2024 |
| NCT05228002 | Recruiting | N/A | sFlt-1/PlGF Ratio: Impact on the Management of Patients With Suspected Pre-eclampsia | May 23, 2023 | July 1, 2025 |
| NCT05500989 | Recruiting | PlacEntal Acute Atherosis RefLecting Subclinical Atherosclerosis | November 2016 | October 2024 | |
| NCT05625724 | Recruiting | Phase 3 | Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology | August 2, 2023 | May 2026 |
| NCT05655936 | Recruiting | N/A | Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial | June 29, 2023 | July 1, 2027 |
| NCT05675969 | Recruiting | N/A | Pilot Study of Microvesicles in Pre-eclamptic and Non-pre-eclamptic Women With Threatened Preterm Delivery | May 31, 2023 | May 15, 2024 |
| NCT05752955 | Recruiting | N/A | SMART Health Pregnancy 2 - Intervention to Reduce Anaemia and Cardiometabolic Risk During Pregnancy and in the First Year Following Birth | June 6, 2022 | December 2024 |
| NCT06002971 | Recruiting | CONNEQT Pulse Validation Study | August 21, 2023 | December 2024 | |
| NCT06067906 | Recruiting | N/A | Weight Loss Following an Episode of Pre-eclampsia Using a Dissociated or Hypocaloric Diet in Overweight or Obese Patients | September 14, 2023 | September 14, 2028 |
| NCT06069102 | Recruiting | Phase 4 | Optimal Blood Pressure Treatment Thresholds Postpartum | November 15, 2023 | December 1, 2025 |
| NCT06108947 | Recruiting | N/A | Screening for Preeclampsia in Norway With Aspirin Discontinuation at 24-28 Weeks | January 1, 2024 | December 2025 |
| NCT06115122 | Recruiting | PEPPI Study: Identification of Women at Risk for Placental Dysfunction | February 15, 2022 | December 31, 2041 | |
| NCT06180811 | Recruiting | N/A | Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women | January 2, 2024 | November 2025 |
| NCT06261203 | Recruiting | N/A | Low Dose Aspirin for Prevention of Early Pregnancy Loss | July 1, 2023 | July 15, 2025 |
| NCT06281665 | Recruiting | Phase 4 | Treatment With Aspirin After Preeclampsia: TAP Trial | May 29, 2024 | June 1, 2026 |
| NCT06317467 | Recruiting | Role of Anti-C1q Autoantibodies in Pregnancy | September 13, 2023 | December 2026 | |
| NCT06330987 | Recruiting | Fetal Autonomic Nervous sysTem Evaluation | August 13, 2019 | December 28, 2025 | |
| NCT06340152 | Recruiting | Multi-Omics for Maternal Health After Preeclampsia | December 20, 2023 | December 2028 | |
| NCT06408181 | Recruiting | Phase 3 | APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia | June 12, 2024 | June 2029 |
| NCT06413576 | Recruiting | Homocysteine in Critically Ill Preeclampsia | January 19, 2024 | June 1, 2024 | |
| NCT06414655 | Recruiting | Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China | March 1, 2024 | November 30, 2026 | |
| NCT06417411 | Recruiting | Phase 1/Phase 2 | LEARNER- Low dosE AspiRiN prEterm tRial (Angola) | March 16, 2024 | March 16, 2026 |
| NCT00333307 | Suspended | Phase 1 | Evaluation of the Safety of Relaxin in Preeclampsia | October 2006 | |
| NCT00141310 | Terminated | Phase 2 | Sildenafil Citrate for the Treatment of Established Pre-Eclampsia | September 2004 | April 2006 |
| NCT04713228 | Terminated | N/A | Prospective Case-Control Study of Cardiovascular Changes in Pregnancy Related Hypertensive Disorders | July 1, 2021 | January 17, 2024 |
| NCT01348711 | Terminated | Early Placental Insufficiency Screening | May 2007 | May 2011 | |
| NCT02174328 | Terminated | Phase 3 | Prevention of Preeclampsia With Aspirin in Recipients of Donated Oocytes. | May 21, 2014 | April 20, 2018 |
| NCT04092829 | Terminated | N/A | Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer | September 16, 2019 | December 31, 2022 |
| NCT02025426 | Terminated | Phase 4 | Phenylephrine Versus Ephedrine in Pre-eclampsia | September 2012 | July 8, 2016 |
| NCT00469846 | Terminated | Phase 2 | L-Arginine and Antioxidant Vitamins During Pregnancy to Reduce Preeclampsia | January 2001 | November 2006 |
| NCT04402385 | Terminated | Phase 2 | Aspirin to Prevent Preeclampsia in Women With Elevated Blood Pressure and Stage 1 Hypertension (ASPPIRE) | August 6, 2020 | June 22, 2022 |
| NCT02613793 | Terminated | Saccadic Reaction Time and Preterm Pre-eclampsia | January 2016 | May 30, 2019 | |
| NCT03222414 | Terminated | N/A | Non-invasive Versus Invasive Blood Pressure Measurement in the Morbidly Obese Parturient With Severe Preeclampsia | May 1, 2015 | January 18, 2016 |
| NCT01193192 | Terminated | A Retrospective Analysis of Neevo® and NeevoDHA® Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy | July 2010 | November 2010 | |
| NCT03863639 | Terminated | Changes in fMRI and Neurocognitive Function in Women With Pre-eclampsia | July 7, 2014 | April 13, 2022 | |
| NCT01566630 | Terminated | Phase 2 | Safety and Efficacy of RLX030 in Pregnant Women With Pre- Eclampsia | May 2013 | August 2014 |
| NCT05152550 | Unknown status | Factors Predicting Transformation of Non Severe Pre-eclampsia Into Pre-eclampsia With Severe Features | May 1, 2021 | March 30, 2022 | |
| NCT03302260 | Unknown status | N/A | Identifying Methods for Postpartum Reduction of Vascular Events: Pilot Randomized Controlled Trial | September 2019 | November 2019 |
| NCT03349671 | Unknown status | Predictors of Intrauterine Growth Restriction | October 2018 | December 2019 | |
| NCT05434195 | Unknown status | N/A | Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies | June 1, 2021 | June 2024 |
| NCT05436119 | Unknown status | Select Nutrient and Gene Variant Analysis in a Targeted Diet and Lifestyle Intervention Reduces Preterm Birth | July 2022 | October 2023 | |
| NCT03767803 | Unknown status | Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women | October 1, 2018 | December 31, 2020 | |
| NCT03928691 | Unknown status | Impact of Body Mass Index on Serum Maternal and Fetal Magnesium Level | June 30, 2019 | November 2021 | |
| NCT00865683 | Unknown status | Phase 1 | DHA Supplements to Improve Insulin Sensitivity in Obese Pregnant Women (The Omega-3 Pregnancy Study) | April 2009 | July 2011 |
| NCT03917342 | Unknown status | N/A | Electroencephalographic Effects of Spinal Anaesthesia During Caesarean Delivery in Preeclampsia | May 1, 2019 | December 31, 2020 |
| NCT03724786 | Unknown status | N/A | Management of Suspected Preeclampsia Based on 6-hour Versus 24-hour Urine Protein Collection | January 1, 2019 | July 2021 |
| NCT03882099 | Unknown status | Vitamin D Level and Its Relation to Pre-eclampsia and Eclampsia | March 17, 2019 | October 2019 | |
| NCT00262093 | Unknown status | Angiogenesis Markers in Primiparas Versus Multiparas: Relevance to Preeclampsia Incidence | November 2005 | ||
| NCT00215969 | Unknown status | Prospective Study in Pregnant Women With Hypercoagulopathy | January 2004 | October 2007 | |
| NCT00567957 | Unknown status | Phase 4 | Remifentanil for General Anesthesia in Preeclamptics | February 2008 | December 2009 |
| NCT03214393 | Unknown status | Certain Maternal Antibodies in Relation to Doppler in Hypertension With Pregnancy | August 1, 2017 | August 30, 2018 | |
| NCT03717740 | Unknown status | Phase 3 | Esomeprazole for the Prevention of Preeclampsia | December 1, 2018 | January 1, 2022 |
| NCT03200743 | Unknown status | Catestatin and Hypertension in Pregnancy | May 14, 2017 | December 2017 | |
| NCT04126122 | Unknown status | Maternal and Neonatal Outcome in Severe Preeclampsia | February 10, 2019 | February 1, 2020 | |
| NCT03193554 | Unknown status | Diagnostic Value of MicroRNA 210 In Preeclampsia | January 1, 2019 | August 30, 2020 | |
| NCT03112551 | Unknown status | N/A | Safety and Efficacy of Twelve Hours Duration of MgSO4 in the Treatment of Eclampsia in Low Resource Setting in Sudan | December 1, 2018 | June 30, 2019 |
| NCT03111576 | Unknown status | Vascular Changes in Pre-Eclamptic Patients and Its Impact on Pregnancy Outcome. | May 31, 2017 | December 2021 | |
| NCT04287998 | Unknown status | Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia | April 1, 2020 | May 1, 2021 | |
| NCT04291313 | Unknown status | N/A | Vitamin D in Pregnancy | June 8, 2020 | May 2023 |
| NCT04310683 | Unknown status | N/A | Natural Cycle or Stimulated Cycle Versus Hormone Replaced Cycle for Pre-eclampsia Rate | November 10, 2020 | March 10, 2022 |
| NCT03717701 | Unknown status | N/A | Metformin and Esomeprazole in Treatment of Early Onset Preeclampsia | December 1, 2018 | January 1, 2021 |
| NCT02990767 | Unknown status | Prediction of Early Pre-eclampsia From Maternal Factors, Biophysical and Biochemical Markers at First Trimester | June 2016 | June 2019 | |
| NCT02807324 | Unknown status | Women Specific Cardiac Recovery After Preeclampsia | June 2016 | June 2022 | |
| NCT04412681 | Unknown status | N/A | Precision Medicine for Prediction & Prevention of Early Pre-eclampsia | March 1, 2021 | June 1, 2022 |
| NCT02706158 | Unknown status | N/A | Dietary Intervention Program for Pre-eclampsia in Women at Risk | April 2016 | April 2018 |
| NCT02704676 | Unknown status | CA-125 and Severity of Pre-Eclampsia | March 2016 | September 2016 | |
| NCT03605511 | Unknown status | TTP and aHUS in Complicated Pregnancies | September 21, 2018 | March 14, 2020 | |
| NCT04699825 | Unknown status | N/A | Cardiovascular Changes in Infants of Preeclampsia Mother | April 1, 2021 | October 1, 2022 |
| NCT03648970 | Unknown status | Phase 2 | Indonesia Pravastatin to Prevent Preeclampsia Study | March 1, 2018 | December 1, 2020 |
| NCT04720690 | Unknown status | Bioimpedence and Arterial Function Monitoring at Birth and in Infants | December 1, 2020 | December 2023 | |
| NCT03233880 | Unknown status | Phase 4 | Impact of Antichlamydial Treatment on the Rate of Preeclampsia | July 1, 2016 | August 1, 2018 |
| NCT04767438 | Unknown status | Preeclampsia Sequential Screening Using Angiogenic Factors During First Trimester of Pregnancy | March 2021 | September 2022 | |
| NCT03838887 | Unknown status | Comparison Between Uterine Artery Doppler and Placental Vascular Indices in Prediction of Preeclampsia | June 1, 2021 | January 1, 2022 | |
| NCT01891240 | Unknown status | IMproved PRegnancy Outcome by Early Detection | November 2013 | April 2018 | |
| NCT04877119 | Unknown status | sFlt-1:PlGF Ratio in Gestational Diabetes: PREDICTION (PREeclampsia in DIabetiC gestaTION) Study | October 14, 2019 | December 31, 2022 | |
| NCT01623791 | Unknown status | Random Urine Protein-creatinin Ratio to Predict Magnitude of Proteinuria | May 2011 | June 2012 | |
| NCT04908982 | Unknown status | Phase 4 | Aspirin for the Prevention of Preeclampsia in Women With Stage 1 Hypertension | May 28, 2021 | May 31, 2023 |
| NCT03299777 | Unknown status | Correlation Between Changes in Liver Stiffness and Preeclampsia as Shown by Fibroscan | September 5, 2017 | September 30, 2019 | |
| NCT03630276 | Unknown status | N/A | Evaluation of Neutrophil/Lymphocyte Ratio ,Platelet/Lymphocyte Ratio and CRP as Markers of Severity of Pre-eclampsia | August 1, 2018 | August 10, 2018 |
| NCT05123677 | Unknown status | Cardiac Output Monitoring to Predict Pre-Eclampsia and Restricted Growth (COMPaRE) | January 1, 2022 | August 1, 2023 | |
| NCT02419898 | Unknown status | Oxfordshire Women and Their Children's Health | April 2013 | December 31, 2018 | |
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| NCT02031393 | Unknown status | Establishing First Trimester Markers for the Identification of High Risk Twin | September 2009 | July 2014 | |
| NCT00133926 | Unknown status | Phase 2 | Prevention of Pre-Term Birth by Treatment of Periodontal Disease | March 2005 | June 2008 |
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| NCT04604535 | Unknown status | N/A | The BEET-BP Trial - Investigating the Effect of Dietary Nitrates on Hypertension in Pregnancy | October 22, 2020 | December 30, 2022 |
| NCT03196141 | Withdrawn | N/A | Utilization of Somatic Tissue Oxygen Saturation Monitoring in Pregnant Women | October 1, 2018 | October 1, 2019 |
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- Disase is a (Disease Ontology)
- DOID:10763
- Cross Reference ID (Disease Ontology)
- ICD10CM:O14
- Cross Reference ID (Disease Ontology)
- MESH:D011225
- Cross Reference ID (Disease Ontology)
- MIM:189800
- Cross Reference ID (Disease Ontology)
- MIM:609402
- Cross Reference ID (Disease Ontology)
- MIM:609403
- Cross Reference ID (Disease Ontology)
- MIM:609404
- Cross Reference ID (Disease Ontology)
- MIM:614592
- Cross Reference ID (Disease Ontology)
- NCI:C85021
- Cross Reference ID (Disease Ontology)
- ORDO:275555
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:6758009
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0032914
- Exact Synonym (Disease Ontology)
- gestational hypertension
- Exact Synonym (Disease Ontology)
- hypertension induced by pregnancy
- Exact Synonym (Disease Ontology)
- pre-eclamptic toxaemia
- Exact Synonym (Disease Ontology)
- preeclampsia
- Exact Synonym (Disease Ontology)
- preeclampsia/eclampsia
- Exact Synonym (Disease Ontology)
- pregnancy associated hypertension
- Exact Synonym (Disease Ontology)
- pregnancy toxemia
- Exact Synonym (Disease Ontology)
- proteinuric hypertension of pregnancy
- Exact Synonym (Disease Ontology)
- toxaemia of pregnancy
- ICD10 preferred id (Insert disease from ICD10)
- D0012119
- ICD10 class code (Insert disease from ICD10)
- O14
- MeSH unique ID (MeSH (Medical Subject Headings))
- D011225