hand, foot and mouth disease
Information
- Disease name
- hand, foot and mouth disease
- Disease ID
- DOID:10881
- Description
- "A viral infectious disease that results_in infection located_in skin, has_material_basis_in Human coxsackievirus A16 or has_material_basis_in Human enterovirus 71, which are transmitted_by contaminated fomites, and transmitted_by contact with nose and throat secretions, saliva, blister fluid and stool of infected persons. The infection has_symptom fever, has_symptom poor appetite, has_symptom malaise, has_symptom sore throat, has_symptom painful sores in the mouth, and has_symptom skin rash on the palms of the hands and soles of the feet." [url:http\://www.cdc.gov/ncidod/dvrd/revb/enterovirus/hfhf.htm]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06209398 | Active, not recruiting | Phase 4 | Immunogenicity of the Inactivated EV71 Vaccine Combined With Hepatitis B and Group A Meningococcal Vaccine | May 24, 2018 | December 31, 2025 |
| NCT04133584 | Completed | Phase 4 | The Immunogenicity and Safety of the Vaccination of Inactivated Enterovirus 71 Vaccine and Seasonal Influenza Vaccine | September 16, 2019 | November 30, 2021 |
| NCT03909074 | Completed | Phase 3 | Clinical Trial of Enterovirus 71（EV71） Inactivated Vaccine in Children Aged 36-71 Months | March 10, 2019 | November 13, 2019 |
| NCT04111432 | Completed | Phase 4 | Safety and Immunogenicity of Concomitant Administration of EV71 Vaccine With Expanded Programme on Immunization Vaccines | July 26, 2019 | March 25, 2020 |
| NCT01182532 | Completed | N/A | A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease | May 2010 | December 2011 |
| NCT01255124 | Completed | Study on Dynamic Changes of the Maternal Anti-EV71 and Anti-CVA16 Antibody Levels in Infants and Young Children | October 2010 | September 2011 | |
| NCT01267903 | Completed | Phase 1 | A Clinical Trial for Inactivated Vaccine(Vero Cell) Against EV71 in Chinese Healthy Young Adults and Children | January 2011 | June 2011 |
| NCT01376479 | Completed | Phase 1 | Safety and Immunogenicity Study of an Inactivated Vaccine Against Hand, Foot and Mouth Disease Caused by Enterovirus 71 | August 2011 | April 2012 |
| NCT01391494 | Completed | Phase 1 | A Safety Study of Inactivated EV71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Adults, Children and Infants | February 2011 | June 2011 |
| NCT01507857 | Completed | Phase 3 | An Efficacy Trial in Inactivated Enterovirus Type 71 (EV71) Vaccine | January 2012 | March 2013 |
| NCT01508247 | Completed | Phase 3 | A Clinical Trial to Assess the Efficacy and Safety of an Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children Aged 6-35 Months | January 2012 | March 2013 |
| NCT01636245 | Completed | Phase 3 | Immunogenicity and Safety of Three Consecutive Lots of a New Inactivated Enterovirus Type 71 (EV71) Vaccine | July 2012 | February 2013 |
| NCT01769794 | Completed | N/A | Chinese Medicinal Treatment on Mild Hand, Foot, and Mouth Disease: Multicenter, Prospective, Randomized Double-blind, Placebo-controlled Study | June 2011 | October 2011 |
| NCT01940250 | Completed | Phase 2 | Magnesium Sulphate for Severe Hand, Foot and Mouth Disease in Vietnam | April 21, 2014 | December 28, 2016 |
| NCT02001233 | Completed | A Follow-up Study for a Phase III, Efficacy Trial in Inactivated Enterovirus Type 71 (EV71) Vaccine | March 2013 | October 2014 | |
| NCT03241030 | Completed | Phase 2 | Sucralfate to Improve Oral Intake in Children With Infectious Oral Ulcers: a Randomized, Double-blind, Placebo-Controlled Trial | September 12, 2017 | June 20, 2019 |
| NCT03274102 | Completed | Phase 4 | Safety and Immunogenicity of Concomitant Administration of EV71 Vaccine With EPI Vaccines | April 22, 2017 | November 1, 2017 |
| NCT03278132 | Completed | Phase 4 | Phase IV Clinical Trial, Immunogenicity and Safety of EV71 Vaccine | July 16, 2017 | September 15, 2017 |
| NCT03281174 | Completed | Five-year Immune Persistence Study of Inactivated Enterovirus Type 71 (EV71) Vaccine | May 20, 2017 | May 21, 2017 | |
| NCT03582761 | Completed | Phase 4 | Efficacy Evaluation for Inactivated Vaccine (Vero Cell) Against EV71 | May 1, 2019 | May 1, 2020 |
| NCT05637229 | Completed | A Serosurvey Study of Hand, Foot, and Mouth Disease in Indonesia | November 28, 2022 | December 19, 2022 | |
| NCT03873740 | Completed | Phase 4 | Immunogenicity and Safety of Two Different Commercial EV71 Vaccines | November 6, 2018 | January 23, 2019 |
| NCT03893747 | Completed | Phase 4 | Immunity and Safety of Inactivated Enterovirus 71 Vaccine Post-marketing Among Children Aged 6-35 Months in China | April 1, 2019 | May 1, 2020 |
| NCT03903926 | Completed | Phase 4 | Efficacy Trial of a Commercial EV71 Vaccine | March 26, 2019 | October 30, 2020 |
| NCT06251219 | Not yet recruiting | Active Case Finding of Clinical Hand Foot Mouth Disease in Children Aged 6 Months Old to 18 Years Old in Indonesia | February 1, 2024 | June 30, 2025 | |
| NCT05397587 | Not yet recruiting | Phase 4 | An Immunity Persistence Study of Enterovirus 71 Inactivated Vaccine (Vero Cell) | July 30, 2022 | October 30, 2025 |
| NCT06263439 | Recruiting | Surveillance of HFMD in Pediatric Outpatients | June 20, 2023 | June 20, 2028 | |
| NCT06063057 | Recruiting | Phase 1/Phase 2 | Inactivated Bivalent Enterovirus Vaccine (Vero Cell) Phase I/II Clinical Trial | September 20, 2023 | April 10, 2025 |
| NCT06146088 | Recruiting | Phase 4 | Lot-to-lot Consistency Study of Three Commercial Batches of Enterovirus 71 Vaccine | November 25, 2023 | July 15, 2026 |
| NCT04182932 | Unknown status | Phase 1 | Safety and Immunogenicity of CJ-40010 in Healthy Subjects | December 2, 2019 | December 2021 |
| NCT03804749 | Unknown status | Phase 1 | Study to Evaluate the Tolerance and Pharmacokinetics of Suramin Sodium | December 19, 2018 | December 19, 2020 |
| NCT01175915 | Unknown status | N/A | A Clinical Trial To Evaluate Reduning Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease | May 2010 | August 2010 |
| NCT01145664 | Unknown status | N/A | A Multi-Center Clinical Trial To Evaluate Chinese Herbal Medicines in the Treatment of Severe Hand-foot-mouth Disease | May 2010 | |
| NCT01182025 | Unknown status | N/A | A Clinical Trial to Evaluate the Effectiveness and Safety of Xiyanping Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease | June 2010 | December 2011 |
| NCT04637919 | Unknown status | Phase 1 | Safety and Immunogenicity of High-dose IN-B001 in Healthy Subjects | December 2020 | December 2021 |
| NCT05166044 | Unknown status | Safety Observation of Enterovirus 71 Inactivated Vaccine (Vero Cell) Combined Immunization in Shanghai | January 4, 2022 | August 10, 2022 |
- Disase is a (Disease Ontology)
- DOID:934
- Cross Reference ID (Disease Ontology)
- ICD10CM:B08.4
- Cross Reference ID (Disease Ontology)
- ICD9CM:074.3
- Cross Reference ID (Disease Ontology)
- MESH:D006232
- Cross Reference ID (Disease Ontology)
- NCI:C128439
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:175497008
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0018572
- Exact Synonym (Disease Ontology)
- Vesicular stomatitis and exanthem
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006232