corneal neovascularization

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Information
Disease name
corneal neovascularization
Disease ID
DOID:11382
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00004430 Completed N/A Randomized Study of Photodynamic Therapy Using Dihematoporphyrin in Patients With Corneal Neovascularization September 1994 September 1998
NCT00471406 Completed N/A Photodynamic Therapy With Verteporfin for Corneal Neovascularization
NCT00512876 Completed N/A Effectiveness and Safety of Topical Bevacizumab (Avastin) for Treatment of Corneal Neovascularization August 2007 January 2011
NCT00555594 Completed Phase 2/Phase 3 Prospective Study to Determine the Effect of Subconjunctival Bevacizumab (AVASTIN) in Corneal Neovascularization September 2006 October 2007
NCT00559936 Completed Phase 1 Topical Avastin for Treatment of Corneal Neovascularization February 2007 October 2010
NCT00681889 Completed Phase 1 Effectiveness and Safety of Topical Ranibizumab for Treatment of Corneal Neovascularization (NV) April 2008 September 2010
NCT00769145 Completed Phase 1 Ranibizumab for the Inhibition of Neovascularization in the Cornea Following Corneal Transplant Surgery October 2008 March 2012
NCT00797303 Completed Phase 4 The Effect of Bevacizumab on Corneal Neovascularization January 2006 November 2008
NCT01072357 Completed Phase 1/Phase 2 Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival December 2009 January 2015
NCT01257750 Completed Phase 1/Phase 2 Treatment of Corneal Neovascularization With Topical Pazopanib November 2010 January 2012
NCT01996826 Completed Phase 1/Phase 2 A Multi-Center Study of the Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival April 2014 April 2019
NCT06412718 Not yet recruiting Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies May 2024 April 2026
NCT05659940 Recruiting Correlation Between a Novel Subset of Neutrophil and Corneal Neovascularization. January 1, 2023 November 30, 2023
NCT04787471 Recruiting Phase 2/Phase 3 Corneal Crosslinking for Treatment of Corneal Neovascularization May 3, 2021 July 15, 2025
NCT02797704 Terminated Phase 1/Phase 2 Subconjunctival Aflibercept (EYLEA®) for the Treatment of Corneal Neovascularization March 2, 2017 September 10, 2019
NCT01868360 Terminated Phase 1 Using Aflibercept Injection to Treat Blood Vessel Growth Over the Cornea June 2013 October 2015
NCT00915590 Terminated Phase 1/Phase 2 Topical IL-1-Ra for Treatment of Corneal Neovascularization April 2009 March 2011
NCT00992849 Unknown status Phase 2 Bevacizumab for the Treatment of Corneal Neovascularization May 2009 April 2012
NCT04215393 Unknown status Phase 1 An Exploratory Clinical Trial Evaluating the Tolerability and Efficacy of KH906 in Patients With Corneal Neovascularization July 18, 2019 December 2020
NCT04620109 Unknown status Phase 1 Clinical Evaluation of Safety and Tolerability of KDR2-2 Eye Drops in Healthy Volunteers With Pharmacokinetic Assessment August 26, 2020 June 30, 2021
NCT05011916 Unknown status Phase 1/Phase 2 The Safety and Efficacy of KDR2-2 Suspension Eye Drops in the Treatment of Corneal Neovascularization August 10, 2021 August 9, 2022
NCT00515684 Withdrawn N/A Corneal Thinning During Topical Bevacizumab Therapy May 2007 December 2008
NCT02042027 Withdrawn Phase 1 Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory Conditions July 2014 July 2016
Disase is a (Disease Ontology)
DOID:4677
Cross Reference ID (Disease Ontology)
ICD10CM:H16.4
Cross Reference ID (Disease Ontology)
ICD9CM:370.6
Cross Reference ID (Disease Ontology)
MESH:D016510
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:19161004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0085109
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0011496
MedGen concept unique identifier (MedGen Concept name)
C0085109
MedGen unique identifier (MedGen Concept name)
43103
ICD10 preferred id (Insert disease from ICD10)
D0006064
ICD10 class code (Insert disease from ICD10)
H16.4
MeSH unique ID (MeSH (Medical Subject Headings))
D016510