leiomyoma

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Information
Disease name
leiomyoma
Disease ID
DOID:127
Description
"A cell type benign neoplasm that is a benign tumor of smooth muscle cells." [url:http\://en.wikipedia.org/wiki/Cancer, url:http\://en.wikipedia.org/wiki/Leiomyoma]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
NCT ID Status Phase Summary Start date Completion date
NCT04655144 Active, not recruiting Phase 3 Dexamethasone for Post Uterine Artery Embolization Pain January 25, 2021 December 15, 2024
NCT03323905 Active, not recruiting N/A Single Arm Study Using the Symphony -- MRI Guided Focused Ultrasound System for the Treatment of Leiomyomas November 16, 2017 June 1, 2024
NCT00087841 Completed Phase 2 Self-Hypnotic Relaxation Therapy During Invasive Procedures April 2002 November 2006
NCT00100191 Completed Phase 3 Emmy Trial: Uterine Artery Embolization (UAE) Versus Hysterectomy for Uterine Fibroids February 2002 April 2006
NCT00131365 Completed N/A Magnetic Resonance (MR) Guided Focused Ultrasound Surgery of Uterine Fibroids January 2006 February 2009
NCT00133705 Completed Phase 3 Trial of Mifepristone for Fibroids July 2003 June 2010
NCT00150644 Completed Phase 2 A Study to Evaluate the Effects of Asoprisnil(J867) in Women With Uterine Fibroids Who Are Scheduled for a Hysterectomy July 2003 May 2005
NCT00152256 Completed Phase 3 A Study to Evaluate of the Safety and Effectiveness of Asoprisnil in Treating Women With Uterine Fibroids September 2003 February 2005
NCT00152269 Completed Phase 3 Treatment of Uterine Fibroids With Asoprisnil(J867) July 2002 January 2005
NCT04996498 Completed N/A Hemostatic Effect of Intrauterine Instillation of Oxytocin in Hysteroscopic Myomectomy April 15, 2021 October 1, 2022
NCT00156156 Completed Phase 3 Study of Asoprisnil in the Treatment of Uterine Fibroids. November 2004 February 2007
NCT00156182 Completed Phase 2 A Long-Term Safety Study of Asoprisnil in the Treatment of Uterine Fibroids. April 2001 December 2001
NCT00156195 Completed Phase 3 Study to Evaluate the Safety of Asoprisnil in the Treatment of Uterine Fibroids September 2003 January 2007
NCT00156208 Completed Phase 3 Safety of Treatment of Uterine Fibroids With Asoprisnil April 2004 December 2006
NCT00160381 Completed Phase 3 A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroids September 2002 January 2005
NCT00160459 Completed Phase 2 A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroids May 2000 July 2001
NCT00290251 Completed Phase 2 Treatment of Uterine Fibroids With the Selective Progesterone Receptor Modulator CDB-2914 February 2006 August 2010
NCT04030182 Completed Vitamin D Deficit in Women With Uterine Fibroids December 1, 2019 October 9, 2021
NCT00361036 Completed Phase 1 Comparison Study in the Treatment of Uterine Fibroids Uterine Fibroid Embolization Using BeadBlock™ Embolic Agent August 2006 March 2010
NCT03815344 Completed Phase 4 Combined Vaginal Misoprostol and Perivascular Vasopressin April 26, 2017 June 30, 2019
NCT03427671 Completed N/A OCL 500 Treatment of Women With Symptomatic Uterine Fibroids January 17, 2018 September 3, 2019
NCT00628901 Completed Phase 4 A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE) January 2006 January 2011
NCT03420248 Completed N/A Comparison of Pain of Two Different Methods in Uterine Artery Embolization April 19, 2018 May 8, 2019
NCT00731341 Completed N/A Hysteroscopic Cryomyolysis for the Treatment of Submucosal Leiomyomata July 2008 February 2009
NCT00746031 Completed Phase 4 Novel MRI Strategies as a Non-invasive Biomarker in Women With Uterine Fibroids December 2008 September 2010
NCT02270255 Completed Phase 2 Superior Hypogastric Nerve Block for Pain Control Post-uterine Fibroid Embolization April 2015 November 1, 2017
NCT00044876 Completed Phase 2 Treatment of Uterine Fibroids With CDB-2914, an Experimental Selective Progesterone Receptor Antagonist September 2, 2002 October 1, 2015
NCT02465814 Completed Phase 2 Assess Safety and Efficacy of Vilaprisan in Patients With Uterine Fibroids June 2015 October 2016
NCT03092999 Completed Phase 1 Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1002670 (Vilaprisan) March 28, 2017 July 17, 2017
NCT00891657 Completed N/A Post Market Study for an Adhesion Barrier Following Laparoscopic Myomectomy November 2008 May 2009
NCT01123603 Completed Lower Urinary Tract Infection (UTI) Evaluation in Women With Uterine Leiomyomata May 2010 June 2014
NCT02997787 Completed New Inflammation Markers for Distinguishing Uterine Adenomyosis and Leiomyoma January 2016 November 2016
NCT02889848 Completed Phase 1 Safety and Tolerability of Collagenase Clostridium Histolyticum (EN3835) to Treat Uterine Leiomyoma (Fibroids) October 27, 2016 November 15, 2018
NCT01530802 Completed N/A Temporary Clipping of the Uterine Arteries During Laparoscopic Myomectomy January 2007 December 2009
NCT02777203 Completed N/A Power Morcellation Systems for Laparoscopic Hysterectomy and Myomectomy May 2016 June 30, 2019
NCT02580578 Completed A Multicenter Prospective Non-Interventional Study Assessing the Management of Canadian Women With Uterine Fibroids July 31, 2015 January 31, 2020
NCT02577055 Completed N/A Fertility After Myomectomy Versus Uterine Artery Embolization for Symptomatic Uterine Fibroids April 2016 October 16, 2019
NCT01793584 Completed N/A Surgical Success After Laparoscopic vs Abdominal Hysterectomy February 2013 December 31, 2016
NCT01816815 Completed Phase 1 Study in Healthy Tubal Ligated Women to Evaluate Pharmacodynamics, Safety and Pharmacokinetics of BAY1002670 November 2011 January 2013
NCT02470741 Completed Phase 4 Pilot of Letrozole for Uterine Myomas July 2015 December 2017
NCT02061657 Completed Phase 3 Impact of Misoprostol on Blood Loss In Myomectomy Operations June 2013 July 2014
NCT02123069 Completed Vascular Function and Uterine Fibroids April 2013 March 1, 2018
NCT02131662 Completed Phase 2 Bay1002670, Fibroids, Safety and Efficacy EU,US,Can, Jap May 15, 2014 May 4, 2016
NCT02147158 Completed Phase 3 A Study of the Efficacy and Safety of Ulipristal Acetate Intermittent Treatment for Abnormal Uterine Bleeding Associated With Leiomyomas January 29, 2014 November 24, 2016
NCT02147197 Completed Phase 3 A Study of the Efficacy and Safety of a 3-month Treatment Course of Ulipristal Acetate for the Treatment of Abnormal Uterine Bleeding Associated With Leiomyomas March 31, 2014 March 29, 2016
NCT02189083 Completed Phase 3 Study of Tumor-shrinking Decoction (TSD) to Treat Symptomatic Uterine Fibroids May 2014 February 2016
NCT03369600 Enrolling by invitation N/A Characterisation of Uterine Fibroid Tissue Stiffness August 17, 2018 July 31, 2025
NCT06143631 Recruiting Phase 4 Prescription of Letrozole for Uterine Myoma June 14, 2024 April 30, 2027
NCT03400826 Recruiting Phase 2 Effects of Simvastatin on Uterine Leiomyoma Size August 20, 2018 December 1, 2024
NCT04145518 Recruiting Phase 4 Mechanistic Characterization of Uterine Pain October 25, 2019 September 1, 2024
NCT05474794 Recruiting N/A Detective Flow Imaging Endoscopic Ultrasonography in Subepithelial Lesions July 20, 2022 June 20, 2024
NCT05538689 Recruiting Phase 4 Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL) November 20, 2022 April 2026
NCT06135870 Recruiting Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study) November 1, 2023 December 31, 2027
NCT02940041 Terminated Concordance Between Sonography Amd MRI for Presurgical Diagnosis of Uterine Mesenchymal Malignant Tumors September 2016 September 2021
NCT01226290 Terminated N/A Fibroid Ablation Study January 2011 March 2014
NCT03342859 Terminated Phase 1 Mode of Action Study of Vilaprisan and Ulipristal Acetate in Patients With Uterine Fibroids for Whom Surgery is Planned November 16, 2017 January 13, 2020
NCT00710346 Terminated Establishment of Fibroid Tissue Bank June 30, 2008 September 1, 2016
NCT00001850 Terminated Evaluation of Women With Endocrine and Reproductive-Related Conditions May 10, 1999 May 23, 2023
NCT00219778 Terminated Phase 2 A Study on the Efficacy of 10 mg Oral Mifepristone for the Treatment of Symptomatic Uterine Leiomyomas December 2004 February 2010
NCT01998854 Terminated Observational Prospective Study on Patients With Symptomatic Uterine Fibroids Treated With VizAblate® Intrauterine-ultrasound Guided RF Ablation February 2013 January 2015
NCT01581905 Terminated N/A Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution March 2012 June 2013
NCT01539187 Terminated N/A Fibroid Ablation Study - Large Fibroids June 2012 June 2014
NCT01311869 Terminated Phase 2 Green Tea Extract: a Non-Surgical Alternative for Treatment of Uterine Fibroids December 2010 September 2011
NCT03550703 Unknown status Phase 2 Open Label Immunotherapy of Myoma June 1, 2018 December 31, 2019
NCT00299481 Unknown status Tissue Bank of Biological Specimens From Patients With Gynecologic Disease March 2006 January 2011
NCT00155870 Unknown status Health-Related QoL Among Women Receiving Hysterectomy in NTUH June 2005 June 2005
NCT04172272 Unknown status N/A The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures September 24, 2019 December 31, 2021
NCT00574418 Unknown status Phase 1 Far Infrared Radiation Treatment for Uterine Fibroids January 2006 September 2008
NCT00390494 Unknown status Questionnaire Study to Assess Quality of Life After Treatment of Fibroids December 2005 December 2010
NCT00821275 Unknown status Phase 2/Phase 3 Clinical Trial of Uterine Artery Embolization for Uterine Leiomyoma January 2008 December 2018
NCT04214457 Unknown status Development of a Predictive Model for Early Differential Diagnosis of Uterine Leiomyomas and Leiomyosarcomas September 20, 2019 July 2022
NCT05151393 Unknown status Correlation Between Serum Vitamin D3 and Incidence of Uterine Leiomyoma December 1, 2021 February 15, 2022
NCT01768104 Unknown status N/A ESTD vs. VATS for Upper Gastrointestinal Submucosal Tumors December 2011 December 2013
NCT00827645 Withdrawn Uterine Artery Embolization and Pelvic Floor Symptoms January 1, 2009 January 1, 2013
NCT00768742 Withdrawn N/A Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual Bleeding: the Fibroid Ablation Study September 2008 November 2010
Disase is a (Disease Ontology)
DOID:0060084
Cross Reference ID (Disease Ontology)
ICDO:8890/0
Cross Reference ID (Disease Ontology)
MESH:D007889
Cross Reference ID (Disease Ontology)
NCI:C3157
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:1162890002
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0023267
Exact Synonym (Disease Ontology)
leiomyomatous neoplasm
Exact Synonym (Disease Ontology)
leiomyomatous tumor
MeSH unique ID (MeSH (Medical Subject Headings))
D007889