dental caries

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Information
Disease name
dental caries
Disease ID
DOID:216
Description
"A teeth hard tissue disease that is characterized by damage to a tooth that can happen when decay-causing bacteria in your mouth make acids that attack the tooth’s surface, or enamel." [url:https\://www.nidcr.nih.gov/health-info/tooth-decay]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04898465 Active, not recruiting N/A Improving Family's Adherence to Dental Care After DGA (HECC-CAN-study) February 26, 2021 March 1, 2025
NCT04933331 Active, not recruiting Early Caries Lesion Management Observational Study December 7, 2020 March 31, 2024
NCT04052685 Active, not recruiting N/A Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions November 28, 2018 May 28, 2024
NCT03916926 Active, not recruiting N/A Older Adult Effectiveness of 2 Treatments September 18, 2019 June 30, 2025
NCT05733923 Active, not recruiting N/A Evaluation of Chemo-mechanical Caries Removal Materials in Caries Removal February 25, 2023 May 15, 2024
NCT03329170 Active, not recruiting N/A Improved Oral Health and Dental Care in Children With Congenital Heart Disease July 1, 2017 December 31, 2030
NCT04672070 Active, not recruiting N/A Selective Caries Removal (SCR) Versus Pulpotomy in Preventing Pulp Necrosis and Apical Periodontitis May 31, 2019 June 30, 2025
NCT05418400 Active, not recruiting N/A Clinical Evaluation of Different Resin Composite Restorations August 15, 2022 November 1, 2023
NCT06155773 Active, not recruiting N/A Clinical Performance of Onlay Restorations After Cervical Margin Relocation (CMR) August 24, 2021 January 2025
NCT04475679 Active, not recruiting N/A Clinical Evaluation of Adhese Universal DC in the Indirect Restorative Therapy September 4, 2020 December 31, 2026
NCT03547128 Active, not recruiting Iowa Fluoride Study/Iowa Bone Development Study March 1, 1992 January 15, 2025
NCT04320576 Active, not recruiting N/A Clinical Comparison of Bulk-fill Restorative and Nano-fill Resin Composite May 1, 2013 May 1, 2025
NCT02999230 Active, not recruiting N/A Probiotics That Moderate pH and Antagonize Pathogens to Promote Oral Health February 22, 2017 December 2025
NCT05008718 Active, not recruiting N/A Silver Diamine Fluoride: A Randomized Controlled Trial on Its Effectiveness As A Caries Arresting Agent June 21, 2022 February 2024
NCT04271150 Active, not recruiting N/A Efficiency of Different Modes of Universal Adhesive May 1, 2018 May 1, 2025
NCT06222918 Active, not recruiting N/A Investigation of the Effect of Deep Margin Elevation Technique on the Clinical Performance of Endocrown Restorations Produced by Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) System December 25, 2022 April 25, 2024
NCT00526422 Completed DPBRN Assessment of Caries Diagnosis & Caries Treatment February 2006 January 2007
NCT00541060 Completed N/A Study of Factors of Genetic Susceptibility Associated to Severe Caries Phenotype October 2007 November 2009
NCT00612469 Completed N/A The Use of Antimicrobial Agents in the Inhibition of Mutans Streptococci in Children With Dental Caries October 2005 October 2006
NCT00638677 Completed Phase 4 Bifidobacterium Lactis BB12 and Xylitol Delivered With a Novel Slow-release Pacifier June 2004 August 2012
NCT00642252 Completed Phase 1 Development and Validation of a Multi-Mineral Fluoride Mouthrinse January 2012 December 2013
NCT00643461 Completed Clinical Evaluation of Three Dental Adhesive Systems in Class V Restorations April 2008 June 2012
NCT00658138 Completed N/A Clinical Evaluation of 3M™ ESPE™ Adper™ Scotchbond™ SE Self-Etch Adhesive in Class I and Class II Restorations in Adults December 2008 December 2011
NCT00703001 Completed N/A Waukesha Smiles: Dental Outreach to Low-income Waukesha Children April 2008 April 2010
NCT00708305 Completed Phase 3 Evaluation of Plaque Fluid Fluoride Retention From Fluoride Toothpastes June 2008 October 2008
NCT00719238 Completed N/A A Pilot Study to Promote Maternal and Infant Oral Health January 2007 July 2008
NCT00723515 Completed Phase 4 Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study February 2007 October 2007
NCT00739778 Completed Phase 2 Effect of a Novel Sweetener on the pH of Dental Plaque. August 2008 December 2008
NCT00847470 Completed DPBRN Reasons for Placing the First Restoration on Permanent Tooth Surfaces June 2006 December 2008
NCT00875212 Completed Phase 1 Effect of Calcium Glycerophosphate (CaGP) - Fluoride Dentifrice on Dental Biofilm pH January 2006 July 2008
NCT00881790 Completed The Behaviour of Dental Nurses Applying Fluoride Varnish to Young Children April 2009 December 2011
NCT00894816 Completed N/A Probiotics in Prevention of Allergies, Obesity and Caries August 2000 November 2020
NCT00902395 Completed Phase 4 Efficacy of Moderate Sedation for Dental Treatment of Young Children June 2008 May 2012
NCT01049503 Completed Phase 3 Effect of pH and Fluoride Concentration of Dentifrices on Caries Control November 2009 February 2012
NCT01123330 Completed Phase 2 Evaluation of a Brief Tailored Motivational Intervention to Prevent Early Childhood Caries October 2001 October 2007
NCT01128946 Completed Phase 4 Enamel Remineralization Potential of Dentifrices in Situ November 2009 March 2010
NCT01129440 Completed Phase 2 Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries June 2011 March 2016
NCT01176396 Completed N/A CAMBRA - PBRN Caries Management By Risk Assessment In A Practice-Based Research Network April 2012 May 2017
NCT01201395 Completed DPBRN Longitudinal Study of Repaired or Replaced Dental Restorations September 2009 September 2011
NCT01201408 Completed DPBRN Longitudinal Study of Dental Restorations Placed on Previously Un-restored Surfaces November 2007 September 2011
NCT01201447 Completed DPBRN Prevalence of Questionable Occlusal Caries Lesions August 2008 March 2010
NCT01201876 Completed DPBRN Reasons for Replacement or Repair of Dental Restorations November 2008 March 2010
NCT01244997 Completed Phase 3 Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites November 2003 May 2009
NCT01268605 Completed Phase 3 Postoperative Hypersensitivity Randomized Comparative Effectiveness Research Trial September 2010 April 2012
NCT01296945 Completed N/A Nutrition Knowledge for Spanish-speaking Parents February 2011 September 2011
NCT01309958 Completed DPBRN Development of a Patient Based Provider Intervention for Early Caries Management June 2008 October 2010
NCT01309971 Completed DPBRN Longitudinal Study of Questionable Occlusal Caries Lesions August 2008 December 2011
NCT01310283 Completed N/A Caries Management by Risk Assessment in Children April 2010 May 2012
NCT01369108 Completed N/A Clinical Study on a New Flowable Composite as a Restorative in Adult Teeth January 2011 December 2013
NCT01369134 Completed Clinical Evaluation of a Self-etch Adhesive Using a Selective Etch Technique January 2011 February 2013
NCT01417832 Completed Phase 2/Phase 3 Radiographic Progression of Sealed and Infiltrated Caries Lesions in Vivo January 2008 March 2011
NCT01438866 Completed Phase 4 Use of Fissure Sealants on Primary Molars October 2011 April 2013
NCT01446107 Completed N/A Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries December 2007 December 2010
NCT01449136 Completed N/A Use of Antibacterial Cement in Infected Dentin January 2008 February 2010
NCT01463826 Completed Respiratory Problems and Caries in Children With Bruxism May 2010 August 2011
NCT01468727 Completed N/A Study on Use of Xylitol-wipes to Prevent Dental Caries January 2007 January 2008
NCT01473537 Completed Phase 1 Optimised Fluoride Prevention by Double Rinse With Fluoride and Calcium October 2011 September 2012
NCT01484132 Completed N/A Composites and Urinary Bisphenol-A Study February 2012 June 2014
NCT01496456 Completed N/A Radiographic Progression of Infiltrated Caries Lesions In-vivo May 2010 July 2014
NCT01502566 Completed Phase 3 Educational Intervention in Preventing Early Childhood Caries June 2010 December 2012
NCT02101255 Completed N/A Effect of Curodont™ Repair in Patients With Early Approximal Carious Lesions July 2014 June 26, 2017
NCT00065988 Completed Phase 3 The Children's Amalgam Trial September 1997 March 2005
NCT00066950 Completed Phase 3 Prevention Management Model for Early Childhood Caries (MAYA Project) March 2003 August 2005
NCT00066963 Completed Phase 3 Fluoride Varnish Randomized Clinical Trial October 2002 December 2006
NCT00067353 Completed Phase 3 Yakima Head Start Fluoride Varnish Study November 2003 August 2005
NCT00100204 Completed Salivary Proteins in Disease and Health December 21, 2004 April 19, 2011
NCT00103493 Completed Phase 3 Oral Health Education Program October 2004 August 2005
NCT00175318 Completed N/A Testing a Tooth Decay Prevention Program With Cree Mothers and Infants April 2005 February 2011
NCT00187837 Completed N/A The CAP-1 Trial: Stepwise Excavation Versus One Completed Excavation in Deep Caries February 2005 June 2013
NCT00226148 Completed Early Phase 1 Immediate Implant Placement in the Molar Regions September 2005 September 2009
NCT00328224 Completed Oral Status and Prevalence of Dental Trauma in Children Treated With Ritalin Due to Attention-Deficit Hyperactivity Disorder (ADHD) May 2006 October 2007
NCT00393055 Completed Phase 3 Xylitol Adult Caries Trial (X-ACT) January 2007 June 2011
NCT00482573 Completed Phase 1 Dental Anesthesia in Pregnant Women With Rheumatic Heart Disease April 2004 January 2006
NCT00490165 Completed Periodontal and Periapical Inflammation and Pregnancy March 2007 December 2011
NCT00495495 Completed Phase 2/Phase 3 Healozone Study to Evaluate the Safety and Efficacy of the Use of Ozone for Management of Dental Caries February 2007 December 2009
NCT00497029 Completed N/A Early Childhood Caries Prevention at a Pediatric Clinic June 2004 August 2006
NCT02659917 Completed Phase 1 Performance of Glass-ionomer Cements: 2-year Follow-up August 2008 August 2010
NCT02668809 Completed N/A Oral Hygiene Intervention Pilot Study June 2014 June 2018
NCT02669979 Completed N/A Domiciliary Professional Oral Care for Dependent Elderly January 2016 April 2017
NCT02705456 Completed N/A Enamel Caries in Orthodontic Patients October 2014 December 2016
NCT02705729 Completed N/A Clinical Performance of Posterior Glass Ionomer Restorations in Adolescents (KETAC) August 3, 2016 May 2021
NCT02724592 Completed Phase 1/Phase 2 Self Assembling Peptide P11-4 in Patients With Early Occlusal Carious Lesions February 2013 October 2014
NCT02730000 Completed N/A Cost-efficacy of Atraumatic Restorations (ART) Using Different Encapsulated Glass Ionomer Cement July 2016 November 2018
NCT02742038 Completed N/A Effectiveness of Fluoride Varnish in the Prevention of Early Childhood Caries: A Randomized Controlled Trial March 2012 December 2014
NCT02742142 Completed Phase 2/Phase 3 Fluoride Application on Preventing and Arresting Root Caries in Fluoridated and Non-fluoridated Areas October 2012 December 2015
NCT02751320 Completed N/A Efficacy of Three Toothpastes Using an in Situ Caries Model February 1, 2016 August 11, 2016
NCT02752594 Completed Phase 2/Phase 3 Consumption of Probiotics on Salivary Bacteria Causing Dental Caries April 2015 April 2015
NCT02767050 Completed Incidence of Caries in Smoking and Smokeless Tobacco December 2015 February 2016
NCT02771522 Completed N/A Caries Lesion Activity in Orthodontic Patients - Calcivis System February 15, 2017 June 5, 2018
NCT02778503 Completed N/A Effectiveness of Atraumatic Restorative Treatment Using Glass Ionomer Cement of Different Costs April 2016 November 2017
NCT02780856 Completed N/A Safety and Performance Evaluation of the Calcivis System January 14, 2017 June 21, 2017
NCT02782390 Completed N/A Efficacy of Hall Technique in Atypical Lesions on Primary Teeth June 2016 December 2017
NCT02795728 Completed Phase 4 Fuji Type VII Sealant Versus Resin Based Sealant. A Clinical Trial February 2010 March 2011
NCT02809014 Completed N/A In Vivo Evaluation of an Experimental Fluoride-containing Dentifrice With Hydrocolloid February 2016 February 2017
NCT02849925 Completed N/A Sealing Microcavitated Carious Lesions March 2015 October 2017
NCT02858947 Completed N/A Three-Year Clinical Evaluation of Class II Posterior Composite Restorations March 2011 January 2015
NCT02873585 Completed N/A Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study April 19, 2018 September 30, 2019
NCT02877888 Completed Phase 1/Phase 2 Effectiveness of Fluoride Varnish in Prevention of Dental Caries in School Children August 2016 November 1, 2018
NCT02885064 Completed Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors August 2016 June 22, 2021
NCT02888873 Completed N/A Comparison of Two Universal Composites in Posterior Teeth May 2014 May 2016
NCT02888912 Completed N/A Clinical Performance of a Glass-ionomer Restorative System: A 6-year Evaluation May 2009 August 2015
NCT02889835 Completed N/A Clinical Performance of Incremental and Bulk Fill Composites in Class II Restorations March 22, 2016 July 3, 2021
NCT02899273 Completed Perception of Children With Visible Untreated and Treated Caries April 1, 2016 February 21, 2017
NCT02908789 Completed N/A Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct Treatment of Deep Carious Lesions in Children March 2016 December 2019
NCT02912000 Completed N/A TEACH: Technology Evaluation to Address Child Health September 2016 March 2017
NCT02921165 Completed Phase 4 Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing May 2016 June 2016
NCT02935322 Completed Phase 4 Interaction Between Chlorhexidine and Fluoride September 2009 February 2012
NCT02937194 Completed N/A Family-centered Oral Health Promotion for New Parents June 2014 December 2019
NCT02962713 Completed N/A Giomer vs Glass Ionomer Cement for ART Occlusoproximal Restorations: a Randomized Clinical Trial November 6, 2017 November 20, 2019
NCT02988349 Completed N/A Ecological Effect of Arginine Dentifrice on Oral Microbiota October 2013 August 2015
NCT02991573 Completed N/A Clinical Study Class II on Ceram.x Universal and Prime&Bond November 2015 March 31, 2022
NCT03004365 Completed Phase 2 A Study to Evaluate the Safety and Microbiology of C16G2 Varnish Administered in Multiple Doses to Dental Subjects January 27, 2017 March 29, 2017
NCT03032705 Completed N/A Clinical Evaluation of Kerr SonicFill™ 2 vs 3M ESPE Filtek™ Supreme Ultra Universal Restorative June 19, 2017 February 5, 2020
NCT03052842 Completed Phase 2 A Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Dental Strip Application February 9, 2017 April 5, 2017
NCT03080649 Completed N/A Laser in Caries Treatment - Patients´View, Pulpal Reactions and Survival of Fillings August 31, 2011 March 28, 2018
NCT03082196 Completed Phase 2 Efficacy Of A PVP-I Fluoride Varnish March 30, 2017 May 7, 2019
NCT03100773 Completed N/A Impact of Atraumatic Restorative Treatment and Oral Health Promotion on Psychological and Salivary Aspects of Children January 2015 November 2015
NCT03101943 Completed N/A Preventing Early Childhood Obesity, Part 1: Family Spirit Nurture, 3-9 Months March 29, 2017 October 18, 2019
NCT03140787 Completed N/A Efficacy and Safety of Primary Teeth Anesthesia Using Nasal Spray in Children May 15, 2016 June 15, 2017
NCT03143387 Completed N/A Discomfort Evaluation During Atraumatic Restorative Treatment in Children June 1, 2017 October 30, 2017
NCT03175627 Completed N/A Clinical Performance of Posterior Composite Tooth Fillings in Adults May 10, 2017 May 31, 2021
NCT03184012 Completed N/A Clinical Evaluation of Zirconia Crowns and Anterior Strip Crowns November 1, 2015 January 30, 2017
NCT03186261 Completed Phase 3 Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique April 1, 2018 December 28, 2018
NCT03186950 Completed N/A Stainless Steel Crowns Versus Bulkfill Composite Resin for Restoring Primary Molars After Endodontic Treatment July 2016 July 10, 2019
NCT03189797 Completed N/A Effect of Tailored Preventive Program on Caires Incidence Using International Caries Classification and Management System (ICCMS) A Randomized Clinical Trial June 30, 2017 July 31, 2018
NCT03196219 Completed Phase 2 A Phase 2 Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Varnish and Strip in Adolescent and Adult Subjects July 7, 2017 January 10, 2018
NCT03214445 Completed N/A Sealing Defective Margins of Composite Restorations With Fluid Composite Resin Nanofiller Reinforced March 1, 2015 May 1, 2017
NCT03221660 Completed N/A Clinical Investigation of the F-Composite 2 System in Direct Filling Therapy January 11, 2018 July 7, 2023
NCT03254069 Completed N/A Occlusal Bite Force Changes After Placement of Stainless Steel Crowns in Children November 2011 December 2012
NCT03267914 Completed N/A Impact of Compliance With Fluoride Use on Caries Incidence After Cancer Therapy August 29, 2017 November 22, 2021
NCT03273725 Completed Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children June 2016 August 2017
NCT03306433 Completed N/A Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant January 8, 2018 December 7, 2018
NCT03312452 Completed N/A The Incidence of IV Fluid Over-administration in Pediatric Dental Surgeries When Infusion Pumps Are Employed September 1, 2018 October 19, 2018
NCT03342066 Completed Reproducibility of Interactive Cariogram Software Versus Manual Caries Risk Assessment Form March 1, 2018 February 10, 2019
NCT03345680 Completed N/A Examining the Impact of School-based Dental Screening October 10, 2017 January 1, 2020
NCT03385629 Completed N/A Providers Against Cavities in Children's Teeth November 15, 2017 December 31, 2022
NCT03395496 Completed Early Phase 1 Comparison of Biodentine and MTA Pulpotomies in the Primary Molar Teeth 3 Year Follow up May 1, 2013 May 30, 2016
NCT03429829 Completed N/A Fluoride Varnish Community Trial February 12, 2018 February 19, 2020
NCT03438045 Completed N/A Implementing a Participatory, Multi-level Intervention to Improve Asian American Health Study May 9, 2018 September 11, 2020
NCT03442309 Completed N/A Comparative Effectiveness of School-based Caries Prevention February 1, 2019 June 30, 2023
NCT03448107 Completed N/A Comparative Effectiveness of Treatments to Prevent Dental Caries September 20, 2017 June 30, 2023
NCT03455621 Completed Phase 4 Effect of the Amount of Fluoride Toothpaste on Fluoride Availability in the Oral Fluids in Children March 1, 2010 June 30, 2011
NCT03457974 Completed N/A Saliva Profiles in Children With Congenital Heart Disease January 1, 2011 January 1, 2012
NCT03520309 Completed N/A Clinical Criteria for the Evaluation of Caries Lesions Around Restorations in Primary Teeth (CARDEC-03) November 16, 2017 September 15, 2021
NCT03527953 Completed N/A A 24-month Clinical Evaluation of Different Bulk-fill Restorative Resins in Class II Restorations November 2013 January 2016
NCT03542019 Completed N/A Survival of Endocrowns Made From Different Ceramics July 1, 2018 December 31, 2020
NCT03576326 Completed N/A BEhavioral EConomics for Oral Health iNnovation Trial May 9, 2018 June 30, 2021
NCT03594968 Completed Oxidative Stress in Polycystic Ovary Syndrome With Periodontal Disease and Dental Caries Lesions April 15, 2018 May 15, 2019
NCT03668093 Completed N/A Evaluation of CAMBRA Versus ICCMS Caries Risk Assessment Models Acquisition On Treatment Plan November 1, 2018 December 1, 2019
NCT03678012 Completed Early Phase 1 Evaluation of Anti-biofilm Effects of Ferumoxytol (Feraheme) Using an in Situ Biofilm Demineralization Model June 7, 2018 August 16, 2018
NCT03686475 Completed N/A Is Biodentine, as Successful as, Mineral Trioxide Aggregate March 2015 September 2017
NCT03724864 Completed N/A Edulcorants Effect in Caries Risk Schoolchildren February 1, 2017 May 8, 2018
NCT03763578 Completed N/A Dental Caries Prevention by a Natural Product September 1, 2020 December 30, 2021
NCT03770871 Completed Phase 4 Indirect Pulp Treatment in Primary Molars August 2016 July 2018
NCT03779698 Completed Phase 4 BiodentineTM Versus Formocresol Pulpotomy Technique in Primary Molars May 2014 September 2016
NCT03788616 Completed Phase 3 Fluoride Release,Compressive Strength and Clinical Performance of a Bioactive Restorative Material in ART November 17, 2018 November 17, 2019
NCT03802669 Completed Molecular Assessment of Oral Mutans Streptococcus Isolated From Different Patients January 12, 2019 May 20, 2019
NCT03822403 Completed N/A Clinical Performance Evaluation of a Glass-ionomer Restorative System Evaluation May 1, 2009 January 1, 2019
NCT03855527 Completed Phase 2 Effectiveness of Silver Diamine Fluoride as Cavity Disinfectant After Atraumatic Restorative Treatment in Primary Teeth January 12, 2018 March 20, 2019
NCT03862014 Completed N/A Management of Molar Incisor Hypomineralization With Silver Diamine Fluoride or SMART July 1, 2019 June 1, 2022
NCT03862443 Completed N/A BEhavioral EConomics for Oral Health iNnovation Pilot Trial May 10, 2017 March 19, 2018
NCT03881020 Completed Phase 4 Comparison of Silver Modified and Conventional Atraumatic Restorative Treatment Modalities August 3, 2020 December 30, 2021
NCT03921307 Completed Clinical Performance of Ceramic CAD/CAM Crowns May 15, 2017 December 21, 2018
NCT03928587 Completed N/A Effect of 12 Months Supplementation With a Symbiotic Lozenge on Caries Increment in Healthy Children May 1, 2019 October 8, 2021
NCT03956992 Completed N/A Effects of a Hydroxyapatite-based Mouth Gel on Calcium Content of Plaque August 8, 2019 August 10, 2019
NCT03971981 Completed N/A Xylitol Chewing-gums: Concentration in Saliva and Antibacterial Effect February 1, 2018 May 28, 2019
NCT04059250 Completed N/A Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite May 28, 2019 March 10, 2020
NCT04081025 Completed Oral Health and Risk Factors for Oral Disease January 1, 2018 January 31, 2023
NCT04101617 Completed N/A Improving Dental Health Among Toddlers in the Dominican Republic February 13, 2019 August 1, 2021
NCT04127929 Completed N/A Investigation of Glass Carbomer Performance September 9, 2017 September 10, 2018
NCT04136639 Completed N/A The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract June 1, 2019 October 1, 2019
NCT04183231 Completed Phase 2 Pharmacokinetics of Advantage Anti-Caries Varnish November 1, 2016 April 25, 2018
NCT04184271 Completed Phase 2 Pharmacokinetics of Advantage Arrest August 1, 2017 March 31, 2019
NCT04186065 Completed The Prevalence of White Spot Lesions During Orthodontic Treatment With Fixed Appliances March 1, 2019 October 31, 2019
NCT04186663 Completed Phase 2 Pharmacokinetics of Advantage Arrest in Children August 1, 2019 March 31, 2020
NCT04199897 Completed N/A Effect of a 2-week Sugar Stress on Bacterial Profiles in Whole Saliva May 5, 2020 June 30, 2020
NCT04250142 Completed N/A Pulp Protection in Selective Carious Tissue Removal March 13, 2019 March 18, 2022
NCT04274920 Completed N/A Dentin Bridge Formation After Indirect Pulp Capping With Bioactive Glass Incorporated in Resin Composite and Its Adhesive in Comparison With Light Cured Calcium Hydroxide March 1, 2017 July 1, 2018
NCT04281433 Completed N/A Clinical Performance of Bulk Fill Composite With Activa Bioactive Liner October 1, 2019 February 1, 2020
NCT04288791 Completed N/A Evaluation of the Clinical Performance of Reinforced Glass Ionomer Restorations June 1, 2018 February 1, 2019
NCT04291872 Completed N/A Heated Glass Ionomer Cement in Primary Molars December 2015 September 2017
NCT04292548 Completed Salivary TAS, TOS, LL-37 and Dental Status in Passive Smoking Children November 16, 2016 August 15, 2018
NCT04298996 Completed Effect of Passive Smoking on Oxidative Stress and Dental Caries in Children November 16, 2016 August 15, 2018
NCT04317768 Completed N/A Effect of Oral Health Education on Oral Health Status, Treatment Needs and Barriers to Care February 1, 2019 June 30, 2020
NCT04390256 Completed N/A Remineralization of Early Carious Lesion Using Natural Agents Versus Bioadhesive Polymers June 1, 2017 May 10, 2020
NCT04399369 Completed Phase 2 Preventing Caries With Silver Diamine Fluoride September 16, 2020 April 30, 2022
NCT04436913 Completed N/A Evaluation of Preventive Regimens With Different Toothpastes vs Fluoride Varnish & Toothpaste in High Caries Patients January 16, 2021 January 31, 2022
NCT04488380 Completed N/A Clinical Performance of Glass Ionomer Versus Resin Composite Restorations October 12, 2015 April 20, 2016
NCT04512482 Completed Phase 2 Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse June 14, 2018 March 4, 2019
NCT04550546 Completed Phase 1 Effects of Nystatin Suspension Oral Application on Oral Microbial Community May 15, 2021 February 28, 2022
NCT04563351 Completed N/A Effectiveness of the Intraligamentary Anesthesia and Inferior Alveolar Nerve Block on Pain During Dental Treatment December 1, 2018 June 15, 2019
NCT04619264 Completed Phase 2 Impact of Minimally Invasive Restorative Techniques on Pregnant Women Oral Health Related Quality of Life January 10, 2019 October 20, 2019
NCT04620252 Completed Early Phase 1 Effect of Chewing a Calcium Supplement Before Fluoride Rinse on Salivary Fluoride February 1, 2021 March 31, 2022
NCT04654624 Completed Phase 2/Phase 3 Child Discomfort and Parental Acceptability of Silver Diamine Fluoride and Alternative Restorative Treatment October 12, 2018 October 30, 2019
NCT04710927 Completed N/A Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric Patients December 1, 2019 November 30, 2021
NCT04750902 Completed Phase 2 A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children January 21, 2021 February 29, 2024
NCT04756557 Completed N/A Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults January 1, 2021 January 9, 2023
NCT04758221 Completed N/A Clinical Performance of Composite Coronal Build -Up in Mutilated Primary Incisors: 3 Years Results June 2016 July 2020
NCT04769882 Completed N/A Er:YAG Laser Effects on Microbial Population in Conservative Dentistry September 7, 2020 December 18, 2020
NCT04777968 Completed Phase 4 Evaluation Of Fluoride Uptake By Dentine Following Silver Diamine Fluoride Under Resin Modified Glass Ionomer Restoration In Carious Primary Molars August 1, 2020 February 1, 2021
NCT04795258 Completed Oral Health Assessment of Children in CP Class January 1, 2021 March 1, 2021
NCT04808557 Completed N/A SEM Evaluation of the Quantity of microRepair® on Resin Composite Surfaces: an in Vivo Randomized Clinical Trial. March 24, 2021 May 10, 2021
NCT04818658 Completed The Preformed Metal Crowns Placed Using the Hall Technique Versus the Conventional Restoration March 8, 2021 December 10, 2021
NCT04867863 Completed SCREENING OF CELIAC DISEASE IN SCHOLAR CHILDREN IN ITALY May 2015 June 2018
NCT04883086 Completed Are Diabetics Type 2 More Prone to Dental Caries? December 15, 2020 November 2, 2021
NCT04971317 Completed N/A The Influence of Simple, Low-Cost Chemistry Intervention Videos: A Randomized Trial of Children's Preferences for Sugar-Sweetened Beverages September 5, 2018 December 30, 2018
NCT05013853 Completed N/A Resin Bulkfill Dual-Cured of Proximal Restoration. Clinical Trial May 15, 2019 December 30, 2021
NCT05052775 Completed N/A EFFICACY OF MORUS ALBA FRUIT EXTRACTS AND CHLORHEXIDINE ON SALIVARY STREPTOCOCCUS MUTANS AND pH LEVELS October 20, 2020 April 3, 2021
NCT05073393 Completed N/A Effect of Probiotics on Oral Homeostasis During Sugar Stress November 3, 2021 June 1, 2022
NCT05123651 Completed N/A Research on the Characteristics and Application of Lactobacillus Rhamnosus X253 as Oral Probiotics November 1, 2020 March 2, 2021
NCT05125731 Completed N/A Effect of Parental Absence on Child's Dental Anxiety and Behaviors During Dental Treatment October 1, 2021 April 1, 2022
NCT05133557 Completed N/A Delivery of Polyphenols in Gum as an Anti-Caries Agent October 1, 2012 November 30, 2015
NCT05143086 Completed Phase 3 Evaluation in Vivo of Mouthwash With Nanoencapsulated Fluoride November 1, 2016 December 20, 2017
NCT05146479 Completed Effectiveness of Sealants and Fluoride Varnish in Caries Prevention in Children With Autism Spectrum Disorders January 1, 2006 June 30, 2021
NCT05146557 Completed Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-study July 1, 2015 October 25, 2015
NCT05191836 Completed N/A Pain and Anxiety Reducing During Dental Treatment in Children Using Video Game on Tablet Device With Joystick. August 15, 2021 November 20, 2021
NCT05201924 Completed N/A Bedtime Routines and Children's Health January 31, 2021 January 31, 2023
NCT05234060 Completed Study of People's Profile Living in France Who Could be Interested in the Use of a Nanohydroxyapatite Toothpaste May 1, 2020 February 1, 2021
NCT05299489 Completed N/A Evaluation Direct and Indirect Composite Restoration in Hypomineralization Molars. October 15, 2020 February 15, 2022
NCT05361278 Completed N/A Evaluation of Gel and Solution of Chlorhexidine in Disinfection Root Canals of Primary Anterior Teeth. January 15, 2021 February 19, 2022
NCT05423392 Completed N/A Efficacy of 4% Articaine Terminal Anesthesia in the Lateral Jaw Region in Children December 2, 2021 February 1, 2023
NCT05427591 Completed N/A Evaluation of the Chemo-mechanical Caries Removal Agent (BRIX3000®) in Primary Molars October 1, 2019 January 1, 2021
NCT05438381 Completed N/A Comparison of Clinical and Radiographic Outcomes of SMART Technique vs ART in Primary Molars September 30, 2019 September 30, 2021
NCT05470959 Completed N/A Bioactive Composite Versus Resin-Modified Glass Ionomer Liners: 2-Year Clinical Trial October 10, 2019 December 20, 2021
NCT05540171 Completed N/A An Educational Intervention Program to Improve the Oral Health of HIV-Positive Children in Kano, Nigeria. December 22, 2022 September 15, 2023
NCT05560945 Completed Phase 3 2-year Caries Clinical Study: Arginine Fluoride-Free Toothpastes vs. NaF Toothpaste April 15, 2019 March 12, 2022
NCT05576142 Completed Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma September 1, 2019 January 25, 2022
NCT05589025 Completed N/A Pulpotomy Versus Pulpectomy in Vital Primary Incisors August 1, 2015 December 15, 2016
NCT05631197 Completed N/A Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis March 2, 2022 September 30, 2023
NCT05655286 Completed N/A Effectiveness of SDF With Different Post-treatment Protocols in Arresting Dental Caries January 1, 2023 May 20, 2024
NCT05667545 Completed Phase 1 Evaluation of the Effect of Self-Assembling Peptide P11-4 July 1, 2021 October 30, 2021
NCT05676671 Completed N/A Microbiological Evaluation and Clinical 24-month Follow-up of Adhesive Systems on Carious Dentin February 2010 February 2020
NCT05779332 Completed Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization February 1, 2020 June 15, 2020
NCT05841589 Completed N/A Evaluation of Antimicrobial Efficacy of Green Tea, Garlic With Lime, Pomegranate Extract and Chlorhexidine Mouth Rinses in a Group of Egyptian Children (In-Vivo Study) February 21, 2018 December 1, 2021
NCT05913258 Completed Phase 3 Caries Removal in Primary Teeth Using Er:YAG Laser January 1, 2020 March 1, 2022
NCT05959382 Completed N/A Evaluation of Clinical Success of Restorations Using Different Magnification Aids October 1, 2021 December 30, 2022
NCT05979636 Completed N/A Novamin on Streptococcus Mutans Count in Dental Plaque of High Caries Risk Children December 6, 2022 January 1, 2023
NCT06100848 Completed N/A Hydrogen Peroxide Fumigation in Dental Office Environment January 3, 2023 September 25, 2023
NCT06132763 Completed N/A Healthy Hydration Pilot in Elementary Schools November 9, 2023 May 1, 2024
NCT06314100 Completed The Effect of Aerosol Formed From Tobacco Heating Systems on the Microbiome of Supragingival Dental Biofilm October 1, 2021 October 25, 2023
NCT06343337 Completed N/A The Effects of Pregnancy on Oral Health May 20, 2022 April 1, 2023
NCT06346756 Completed N/A Clinical Evaluation of Class II Restorations January 1, 2023 July 15, 2023
NCT06348979 Completed N/A Clinical Performance of Fiber Reinforced FRC Base and Bonded CAD/CAM Resin Composite Endocrowns January 1, 2022 January 30, 2024
NCT06393270 Completed 5-year Clinical Follow-up of Restorative Materials November 1, 2017 December 15, 2022
NCT06428474 Completed N/A Implementation of Oral Health Educational Program on Orphan Children September 1, 2023 March 30, 2024
NCT01523509 Completed Phase 1 Use of Radiographic Contrast to Detect Dental Caries August 2012 May 2013
NCT01523613 Completed N/A High-strength Glass-ionomer Dental Restorations November 2011 October 2014
NCT01563172 Completed Phase 4 Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride January 1, 2009 June 1, 2009
NCT01567514 Completed Phase 4 Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining March 2008 March 2011
NCT01569165 Completed N/A Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH February 2011 November 2011
NCT01584024 Completed N/A Resin Infiltration to Arrest Early Tooth Decay March 2013 December 31, 2017
NCT01589458 Completed Phase 1 Fluoride Availability in Saliva After Use of Sodium Fluoride or Monofluorophosphate Toothpastes August 2011 March 2012
NCT01589991 Completed Phase 1 Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes January 2011 July 2013
NCT01604109 Completed Phase 2 Effect of CPP-ACP Paste on Dental Caries in Primary Teeth July 2010 September 2011
NCT01607411 Completed Phase 3 A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model February 2012 May 2012
NCT01623362 Completed Phase 3 Evaluation of a Low Fluoride Dentifrice for Caries Control September 2010 February 2012
NCT01629290 Completed N/A In Vivo Comparison of Salivary Fluoride Levels Following the Application of Different 5% NaF Varnishes June 2012 December 2015
NCT01641861 Completed N/A A Comparative Study of Papacarie® and the Conventional Method for Dental Caries Treatment August 2012 September 2015
NCT01657539 Completed Phase 2/Phase 3 Effect of Probiotics Containing Yogurts on the Composition of Biofilms in Patients Under Orthodontic Treatment August 2011 March 2013
NCT01674933 Completed Phase 4 Fluoride Varnish For Childsmile Nursery School Attenders October 2012 August 31, 2017
NCT01680848 Completed Assessment of Caries Diagnosis and Caries Treatment in Dental PBRN Japan May 2010 February 2015
NCT01683851 Completed Isolite and Dental Treatment Under Conscious Sedation August 2012 June 2013
NCT01707797 Completed Predicting Caries Risk in Underserved Toddlers in Primary Healthcare Settings November 15, 2012 March 30, 2017
NCT01720771 Completed N/A Preventive Effect of a Probiotic Tablet on Oral Health in Preschool Children February 2013 May 2015
NCT01724827 Completed Phase 3 Ceramic Versus Composite in the Treatment of Posterior Teeth by Inlays or Onlays September 13, 2012 March 2017
NCT01757990 Completed Phase 2 The Effect of Stevia Rebaudiana Extracts on Different Variables Related to Caries: an in Vitro and in Vivo Evaluation. March 2012 June 2012
NCT01763138 Completed N/A Effect of Educational Intervention in Mothers for Prevention of Caries in Their Children June 2012 November 2012
NCT01768390 Completed Phase 4 Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients January 2008 October 2012
NCT01797458 Completed N/A European Study on Three Different Approaches to Managing Class 2 Cavities in Primary Teeth May 2011 December 2014
NCT01811420 Completed N/A Chemomechanical Caries Removal Using Papain Gel March 2009 March 2011
NCT01829334 Completed Phase 2 Cost-effectiveness of Four Methods in Preventing Fissure Caries in Permanent Teeth June 2006 May 2009
NCT01854502 Completed N/A Family-based Counseling Models for Young Children January 2008 December 2011
NCT01858298 Completed N/A Conservative Versus Non-conservative Treatment for Severe Dental Caries December 2013 March 2015
NCT01901250 Completed N/A Xylitol for Caries Prevention in Inner-City Children August 2007 December 2011
NCT01924611 Completed N/A Two Years Survival Rate of Class II ART Restorations in Primary Molars Using Two Ways to Avoid Saliva Contamination September 2004 March 2007
NCT01943123 Completed N/A Effect of Probiotic Drink on Number of Salivary Mutans Streptococci in School Going Children February 2011 July 2011
NCT01950546 Completed Phase 1 Nanosilver Fluoride to Prevent Dental Biofilms Growth September 2014 January 2015
NCT01978041 Completed Phase 1 Fluoride Bioavailability After Ingestion of Water or Foods Prepared With Fluoridated Water January 2013 December 2013
NCT02003820 Completed N/A Using Video Modeled Social Stories to Improve Oral Hygiene in Children With Autism Spectrum Disorder July 2014 July 2015
NCT02017886 Completed N/A Salivary IgA and Cytokines Response to Dietary Supplementation of Lactobacillus Reuteri November 2013 April 2016
NCT02018822 Completed N/A Evaluate the Effectiveness of an Experimental Urethane Dimethacrylate Resin Based Dental Composite Material June 2013 September 2017
NCT02019563 Completed Phase 2 MTA/FS Pulpotomy for Vital Primary Incisors: A Randomized Controlled Trial September 2010 September 2014
NCT02020681 Completed N/A Effect of Curodont Repair or Placebo on the Remineralisation in Patients With Class 5 Carious Lesions September 2013 January 2016
NCT02044081 Completed Phase 2 Phase 2, Safety & Microbiology Study of C16G2 in Multiple Oral Gel &/or Mouth Rinse Doses to Healthy Adults February 2014 August 2014
NCT02071953 Completed N/A Comparative Study of Experimental Dental Adhesive With and Without Phosphoric Acid Pretreatment April 2012 September 2014
NCT02078453 Completed N/A Impact of the Radiographic Examination on Diagnosis and Treatment Decision of Caries Lesions in Primary Teeth March 2014 February 2018
NCT02093091 Completed N/A Clinical Evaluation of Nanoionomer Filling in Primary Teeth June 2011 October 2013
NCT02098304 Completed N/A Post-Approval Clinical Study to Evaluate the Calcivis Caries Activity Imaging System May 2014 February 2015
NCT00001726 Completed Study of the Composition of Dental Plaque June 19, 1998 August 3, 2009
NCT02119507 Completed N/A Effect of Curodont Repair in Patients With Early Approximal Carious Lesions April 2013 December 2014
NCT02130206 Completed Phase 2 The Microbiology of Caries Resistance May 2014 November 2014
NCT02168374 Completed Phase 2 Properties of Glass Ionomer Cements Associated With Chlorhexidine or Doxycycline March 2008 October 2011
NCT02234609 Completed N/A Effectiveness of Modified Class IV Atraumatic Restorative Treatment September 2012 October 2013
NCT02254993 Completed Phase 2 Phase 2, Open-Label Study for Safety, Microbiology and PK of Single or Multiple Oral C16G2 Gel Doses October 2014 July 2015
NCT02257203 Completed N/A Primary Care Beverage Study October 2014 December 2015
NCT02263768 Completed N/A Impact of Two Recall Intervals on Dental Caries Incidence, Anxiety and Quality of Life of Preschool Children March 2015 March 2018
NCT02274142 Completed N/A Primary Molars Restorations With Encapsulated or Hand-Mixed Glass Ionomer: Clinical Trial October 2014 October 2016
NCT02338180 Completed Phase 4 Preventive and Therapeutic Proximal Sealants March 2009 November 2012
NCT02340767 Completed N/A Decision Aids for the Management of Suspicious Occlusal Caries Lesions December 2014 December 2016
NCT02357979 Completed N/A Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser February 8, 2018 March 31, 2020
NCT02359279 Completed N/A Radiographic Contrast To Differentiate Cavitated From Non-cavitated Tooth Decay August 2015 June 2016
NCT02360124 Completed Phase 2/Phase 3 Preventing and Arresting Dental Root Surface Caries in Community-dwelling Older Adults January 2012 April 2015
NCT02368028 Completed Oral Alkali Production and Caries Prevention in Children (Cross-sectional Component) March 2015 September 2015
NCT02375763 Completed N/A Dietary Analysis for Caries Prevention in Children Using a Computer Software February 2015 March 2017
NCT02377297 Completed N/A Occlusal ART Restorations in Primary Molars Using 3 Different GIC November 2014 March 6, 2018
NCT02389569 Completed N/A Clinical Study of Biosilicate Under Resin Composite Restorations in Caries Affected Teeth
NCT02395120 Completed N/A Family Access to Dentist Study August 2015 May 2017
NCT02398695 Completed Oral Alkali Production and Caries Prevention in Children (Longitudinal) October 2012 August 27, 2015
NCT02399163 Completed N/A Evaluation of Oral Hygiene Products in an In Situ Caries Model April 2015 August 2015
NCT02405546 Completed N/A ETT Rotation During Nasal Fiberoptic Intubation August 2013 August 2015
NCT02408601 Completed Phase 2/Phase 3 A Clinical Trial to Assess the Retention and Caries Preventive Effect of Resin Based Sealants Versus ART Sealants March 2015 April 2017
NCT02424097 Completed Phase 4 MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study May 2013 October 2016
NCT02426619 Completed Phase 2/Phase 3 Arresting Active Dental Caries in Preschool Children by Topical Fluorides September 2012 April 2015
NCT02437565 Completed N/A Checking Occlusion During Stainless Steel Crown Placement August 2013 April 2015
NCT02443207 Completed Impact of Dental Pain on the Quality of Life January 2013 May 2014
NCT02443896 Completed N/A The Use of Pit and Fissure Sealants in Children Requiring Caries Related Dental Extractions April 2014 August 2018
NCT02447289 Completed Phase 4 Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment May 21, 2015 October 18, 2016
NCT02459730 Completed N/A Glass-ionomer Cement Containing Chlorhexidine for ART February 2013 February 2014
NCT02460562 Completed N/A Caries Prevention Effect of S-PRG Filler Incorporated in Denture Base Resins on Edentulous Elderly People June 2015 January 20, 2017
NCT02473107 Completed N/A Impact of Detecting Initial and Active Caries Lesions in Primary Teeth September 2015 September 2018
NCT02479958 Completed Phase 1 An in Vitro Evaluation of Antimicrobial Photodynamic Therapy on Deciduous Carious Dentin May 2011 January 2014
NCT02486458 Completed Early Phase 1 Long-term Release of Fluoride Formed on Enamel by Fluoride Gel or Varnish to Biofilm Fluid April 2015 December 2016
NCT02490592 Completed Phase 4 Comparison of the Effect of Fluoride Remineralizer Gel and Foam March 2014 August 2014
NCT02509845 Completed Phase 2 Study to Evaluate the Safety and Microbiology of C16G2 in Adolescent and Adult Dental Subjects July 2015 March 2016
NCT02536040 Completed Phase 3 Stopping Cavities Study: Diammine Silver Fluoride January 2016 July 2016
NCT02569047 Completed N/A ART and Hall Technique for Management of Occlusal-proximal Caries in Primary Molars October 2015 November 2018
NCT02573090 Completed N/A Sealing Manifest Occlusal Caries Lesions in the Permanent Dentition November 2006 December 2020
NCT02589743 Completed Phase 2 Randomized Clinical Trial of Occlusal Sealant April 2003 June 2005
NCT02591147 Completed N/A Silver Diamine Fluoride Pilot Study (SDF) January 7, 2016 June 30, 2022
NCT02592278 Completed Phase 4 Prevention of Dental Caries Lesions With Fluoride Varnish in Erupting First Permanent Molars March 2015 March 2016
NCT02594020 Completed N/A Comparison of Different Methods of Enamel Preparation Before Pit and Fissure Sealants June 2008 December 2015
NCT02594254 Completed Phase 2 Phase 2 Study to Evaluate the Microbiology and Safety of C16G2 Administered to Adult and Adolescent Dental Subjects November 2015 September 2016
NCT02604134 Completed Early Phase 1 Medical Management of Caries in the Primary Dentition Using Silver Nitrate July 2014 August 21, 2018
NCT02616198 Completed N/A 6-year Clinical Evaluation of Glass Ionomer Cements (GIS) With Resin Coating on Posterior Teeth January 2009 September 2015
NCT02623283 Completed The Tayside Brushing Study - Adult Follow up December 1, 2015 April 19, 2019
NCT02637830 Completed N/A In Situ Remineralisation Response of Different Artificial Caries-like Enamel Lesions to Home-care and Professional Fluoride Treatments January 2012 December 2012
NCT02639455 Completed N/A Survey of the Collective 16s rRNA Genes From Bacterial Populations From Exercising and Non-exercising Participants February 2016 May 2016
NCT02645617 Completed Phase 1 Safety Evaluation of Advantage Anti-Caries Varnish March 30, 2016 October 20, 2016
NCT02649816 Completed Effectiveness of Resin Sealants: Retrospective Cohort Study March 2011 December 2013
NCT02657538 Completed N/A Validation of Near-infrared Light Transillumination for Interproximal Enamel Caries Detection July 2014 March 2016
NCT05601154 Enrolling by invitation Early Phase 1 Fluoride in Saliva After Use of Fluoride Toothpastes Followed by Fluoride Mouthrinses March 23, 2023 June 30, 2025
NCT05772039 Enrolling by invitation Phase 4 Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life January 18, 2022 August 15, 2023
NCT03433157 Enrolling by invitation N/A Assessment of Stainless Stain Crowns Placed Using the Hall Technique and Traditional Technique August 1, 2019 December 2024
NCT05406011 Enrolling by invitation N/A Effect of Sour Cherry Anthocyanins on Healthy Human Saliva March 16, 2020 December 31, 2024
NCT04630587 Enrolling by invitation N/A Longevity of Dental Fillings Utilizing 3D Printing September 15, 2020 December 31, 2026
NCT05979805 Not yet recruiting N/A Effectiveness of Educational Interventions in the Prevention of Caries in Patients With Orthodontics March 15, 2024 April 20, 2025
NCT06428344 Not yet recruiting Accuracy of an Artificial Intelligence-assisted Diagnostic System for Caries Diagnosis: a Prospective Multicenter Clinical Study June 1, 2024 June 1, 2027
NCT06354647 Not yet recruiting N/A Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves June 15, 2024 June 1, 2027
NCT05965297 Not yet recruiting N/A Comparison of Two GIC's in the Restoration of Posterior Class II Lesions in the Primary Dentition August 2023 August 2030
NCT06003452 Not yet recruiting N/A Retention Rate And Caries Prevention Of Giomer Based Sealant With And Without Pre-Treatment With Bioactive Glass Air Abrasion In Young Adults September 1, 2023 May 1, 2024
NCT04033263 Not yet recruiting N/A Maintaining Oral Health With Bio-products September 2024 December 2026
NCT06081868 Not yet recruiting N/A RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda September 1, 2024 September 1, 2026
NCT06346795 Not yet recruiting N/A Class II Restorations With High-Filled Flowable Composites June 1, 2024 June 1, 2025
NCT05766696 Not yet recruiting N/A Survival Rate and Cost-effectiveness of Conventional vs ART Restorations in a School Setting May 2023 May 2025
NCT06169306 Not yet recruiting N/A Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat? January 1, 2024 April 30, 2024
NCT05466461 Not yet recruiting N/A Clinical Assessment of Giomer Based Technology Versus Smart Bioactive Restoration in Carious Class V Cavities November 1, 2022 January 1, 2024
NCT03037814 Not yet recruiting N/A Clinical Performance of Restorative Materials in Primary Teeth September 28, 2021 March 25, 2027
NCT05980273 Not yet recruiting Effectiveness of Oral Health Education Programs Among School Children, Their Mothers and Teachers in Fayyum: Cohort Study October 9, 2023 October 10, 2024
NCT04602572 Not yet recruiting Obesity and Oral Diseases in Adult Patients August 1, 2024 September 3, 2025
NCT06372366 Not yet recruiting Relationship Between Vitamins Deficiency and Caries Experience Among a Group of Egyptian Children July 15, 2024 December 15, 2025
NCT06354634 Not yet recruiting N/A Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar Teeth July 2024 July 2027
NCT06365281 Not yet recruiting Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Cairo University May 2024 August 2025
NCT06348953 Not yet recruiting N/A Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars April 2024 November 2025
NCT05946473 Not yet recruiting N/A Development of a Novel Anti-caries Chewing Gum July 2023 April 2024
NCT06021028 Recruiting N/A Performance of GIOMER Based Resin Composite August 1, 2023 October 1, 2025
NCT04528134 Recruiting N/A Orthodontic Varnish Microbiology Study February 7, 2022 July 1, 2025
NCT04533113 Recruiting N/A Carious Tissue Selective Removal on Permanent Posterior Teeth. February 20, 2019 July 2026
NCT06006429 Recruiting N/A Intraoral Scanners as Periodontal and Dental Pathologies Diagnosis Tools May 11, 2022 December 11, 2026
NCT03753256 Recruiting N/A Evaluation of Optical Coherence Tomography in Dentistry December 4, 2017 December 2027
NCT03770286 Recruiting Phase 3 Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride January 22, 2019 December 2022
NCT04946292 Recruiting N/A Empowering Older Adults for Healthy Living and Better Dental Health March 29, 2022 June 2024
NCT05816512 Recruiting N/A Antimicrobial Efficacy of Biogenic Gold Nano Particle From Pelargonium Graveolens Leaves Extract Mouthwash for Children April 1, 2023 March 20, 2024
NCT04195607 Recruiting Epidemiological Profile of Children With Early Caries. November 19, 2019 May 2023
NCT06172764 Recruiting Phase 4 A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbiome December 12, 2023 June 2025
NCT06441500 Recruiting N/A Oral Health and Dental Caries Prevention Intervention for Children in Romania January 7, 2024 December 21, 2025
NCT05538559 Recruiting N/A Carie Care, Chemomechanical Caries Removal Technique in Primary Teeth June 1, 2022 October 30, 2022
NCT05902611 Recruiting The Relationship Between Body Mass Index, Dental Eruption and Dental Caries Prevalence in School Children April 21, 2021 September 21, 2023
NCT05910645 Recruiting Knowledge, Attitude and Practice Regarding Caries Risk Assessment for Children and Adults Among Dental Residents October 2023 June 2024
NCT06135792 Recruiting N/A The Effect of Arginine on Biofilm Composition, Architecture and Metabolism October 19, 2023 December 2024
NCT05792631 Recruiting N/A A Study to Compare Caries Detection in the Pediatric Population Between the iTero Element 5D System and Bitewing Radiographs December 8, 2022 June 1, 2024
NCT05606562 Recruiting N/A Drug-free Without Toothache. A Study of Free Dental Treatment as a Part of Substance Abuse Treatment April 6, 2022 December 31, 2026
NCT06350578 Recruiting N/A A Randomized Clinical Trial Comparing Hall vs. Conventional Technique in Primary Molars. December 6, 2023 June 2025
NCT04075474 Recruiting Phase 2 Preventing Early Childhood Caries With Silver Diamine Fluoride October 27, 2020 June 30, 2023
NCT06258798 Recruiting The Use of Artificial Intelligence in the Dental X-rays Analysis January 1, 2024 March 1, 2024
NCT02929914 Recruiting N/A Effect of aPDT on Deep Caries in Permanent Tooth June 2016 December 2025
NCT06276959 Recruiting The Effectiveness of iTero Element 5D NIRI System in Early Proximal Caries Detection in Permanent Teeth January 1, 2023 March 1, 2025
NCT04822233 Recruiting N/A A Comparative Study of Hall Technique, Modified Hall Technique and Conventional Stainless-Steel Crown Restorations in the Treatment of Primary Molars With Proximal Caries Lesions. June 1, 2023 December 1, 2025
NCT05983900 Recruiting N/A Clinical Evaluation and Antimicrobial Effect of Papain Based Chemo-mechanical Caries Removal Agents April 1, 2023 June 2024
NCT03827889 Suspended N/A Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth January 1, 2024 December 30, 2027
NCT03785730 Suspended N/A Non-restorative Cavity Control in Anterior Cavitated Caries Lesion of Primary Teeth April 30, 2019 December 30, 2027
NCT02568917 Suspended N/A Effectiveness of ART and Conventional Treatment - Practice-based Clinical Trial August 2020 August 2022
NCT02598778 Terminated Phase 2 Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction November 1, 2015 April 1, 2016
NCT00067340 Terminated Phase 3 Caries Transmission Prevention in Alaska Native Infants April 2003 July 2006
NCT01147835 Terminated N/A Herbal Lollipops on Oral Bacterial Levels and DMFT/Dmft Scores of Children With Asthma Using Inhalers September 23, 2009 September 27, 2011
NCT02754466 Terminated N/A Oral Health and Its Relation to Development and Well-being of Schoolchildren Before and After Restorative Treatments May 2, 2017 September 28, 2021
NCT04556175 Terminated N/A Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project March 29, 2021 March 1, 2022
NCT02572570 Terminated N/A Clinical Investigation of a New Bulk Fill Composite Resin in the Restoration of Posterior Teeth December 2015 December 5, 2019
NCT00334087 Unknown status The Relation Between Pregnancy,Birth Outcome, Feeding , Oral Hygiene Habits and Early Childhood Caries Development. June 2007 September 2007
NCT03819868 Unknown status N/A Efficacy of Sealing Molars: Split-mouth Randomized Clinical Trial August 15, 2017 December 2019
NCT02494427 Unknown status N/A Comparison of Conventional and CAD/CAM Dental Restorations February 2014 February 2018
NCT02537184 Unknown status N/A Impact of Two Recall Intervals on Dental Caries Incidence and Other Outcomes of Preschool Children September 2014 August 2016
NCT02561689 Unknown status N/A SEALANT-DK: Longevity and Efficacy of 6 Resin Sealants Used for Sealing Permanent Teeth in Children and Adolescents January 2014 December 2022
NCT02562456 Unknown status N/A Cost-efficacy Between ART and Composite Resin Restorations in Primary Molars November 1, 2015 December 10, 2019
NCT02578966 Unknown status N/A Cohort Zero Caries January 2014 December 2021
NCT02584218 Unknown status N/A Effectiveness of Sealing Dental Caries January 2015 February 2017
NCT05096897 Unknown status Oral Health-related Quality of Life (OHRQoL) in Patients With Inflammatory Bowel Disease (IBD) November 2022 November 2023
NCT05117268 Unknown status N/A ASSESSMENT OF SDF vs. GIC AND HALL TECHNIQUE October 1, 2021 February 2022
NCT03963791 Unknown status N/A Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP October 5, 2019 June 1, 2020
NCT03966378 Unknown status N/A Reminerlization Potential of GSE Gel versusCPP-ACP in Carious White Spot Lesions in Post Orthodontic Patients October 3, 2019 May 10, 2020
NCT04050306 Unknown status DIMOH: New Digital Methods for Monitoring Oral Health. An in Vivo Assessment March 27, 2019 December 18, 2020
NCT01142440 Unknown status Phase 4 Dental Caries Management by Risk Assessment: Identification and Treatment of Risk Factors Among (IDF) Personnel June 2010 March 2012
NCT02692625 Unknown status Phase 4 Consumption Effect of Probiotic Products on Salivary Cariogenic Bacterial Counts in Preschool Children. January 2015 April 2016
NCT04096599 Unknown status N/A Is Xylitol Toothpaste Effective in Preventing Tooth Decay? November 18, 2018 June 6, 2021
NCT05149209 Unknown status N/A Evaluation of a New Bioactive Material Versus a Fluoride-Releasing Hybrid Restorative Material in Cervical Lesions December 15, 2021 December 30, 2022
NCT05185206 Unknown status N/A Comparative Evaluation of the Post Operative Sensitivity of Cention-N(Commercially Available Restorative Material) Using Conventional and Polymer Bur- In-vivo Study May 2, 2020 June 30, 2022
NCT05188846 Unknown status Phase 3 Caries Arresting in Primary Molar Teeth Using SDF VS ART January 25, 2022 March 2023
NCT02734420 Unknown status Phase 1 Effect of Photodynamic Therapy With Low-level Laser on Infected Dentin in Primary Teeth: A Controlled Clinical Trial September 2013 October 2016
NCT02735304 Unknown status N/A Clinical Study 3MESPE Crowns October 2016 July 2021
NCT04183777 Unknown status Assessment of the Age, Reasons, Oral Health Status and Dental Treatment Needs of Children in Their First Dental Visit March 1, 2020 March 1, 2021
NCT02751970 Unknown status Phase 2 Clinical Trial of the Effect of Different Categories of Adhesive System April 2014 April 2018
NCT05202665 Unknown status N/A Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion September 26, 2017 September 2022
NCT01477385 Unknown status N/A Treatment of Initial Caries Lesions on Proximal Surfaces of Primary and Permanent Posterior Teeth January 2012 October 2018
NCT01508611 Unknown status N/A Cost-efficacy of Silver Diammine Fluoride in Erupting Molars February 2015 August 2019
NCT04438252 Unknown status N/A Evaluation of Reliability of CarieScan PRO Compared With Digital Radiograph and ICDAS-II in Detection of Carious Lesions September 2020 September 1, 2021
NCT03005405 Unknown status N/A Cost-efficacy of Sealing Moderate Caries Lesions in Occlusal Surfaces of Primary Molars February 2015 December 2018
NCT03008759 Unknown status Phase 1/Phase 2 Evaluation in Vivo of Dentifrice With Nanoencapsulated Fluoride February 2016 February 2017
NCT04446364 Unknown status N/A Ethanolic Extract of Aloe Vera Versus Chlorohexidine as Cavity Disinfectant. September 1, 2020 September 1, 2021
NCT03051594 Unknown status N/A Reliability of Fluorescent Camera and Caries Detection Dye Versus the Visual Tactile Method February 3, 2017 March 30, 2018
NCT04446390 Unknown status N/A Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initial Lesions January 1, 2021 March 1, 2022
NCT03061422 Unknown status N/A Effect of Xylitol-Containing Chewing Gum With/Without Bicarbonate Versus Paraffin Pellet on Salivary pH March 3, 2017 November 30, 2018
NCT03061916 Unknown status Phase 3 Cinnamon and Ginger in Comparison to Chlorhexidine Gluconate 0.2% on Oral Streptococcus Mutans March 2017 November 1, 2017
NCT04475172 Unknown status N/A Evaluation Of Clinical Performance of Self-adhering Flowable Composite vs Conventional Flowable Composite in Cervical Carious Lesions October 2020 October 2021
NCT00972556 Unknown status N/A Comparison of Mineral Trioxide Aggregate (MTA) and 20% Formocresol (FC) in Pulpotomized Human Primary Molars September 2009 July 2014
NCT04491981 Unknown status N/A Restoration Repairs Using Composite Resin Versus Glass Ionomer in Primary Molars: a Randomized Clinical Trial July 1, 2021 August 1, 2023
NCT01680289 Unknown status N/A Influence of the Number of Layers of a One Bottle Adhesive on the Longevity of Composite Restorations in Primary Molars August 2012 August 2015
NCT03143023 Unknown status N/A Efficacy of Dentifrices Containing Arginine Versus Fluoride on Microbial Acid June 2017 February 2018
NCT03184025 Unknown status N/A Effect of Surface Sealant Application on Clinical Performance Occlusal Restorations July 1, 2014 December 29, 2020
NCT03185104 Unknown status N/A Silver Diamine Fluoride for Caries Prevention in Removable Partial Dentures Wearers November 1, 2013 December 31, 2017
NCT00067392 Unknown status Phase 3 Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites November 2003 May 2009
NCT01778699 Unknown status Phase 4 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). February 2013 April 2015
NCT04571931 Unknown status Parental Knowledge, Attitude and Practice Towards Oral Health of Their Children February 1, 2021 July 1, 2021
NCT04593017 Unknown status N/A On Probiotic, Dental Caries, and Orthodontic Patients November 1, 2020 December 21, 2020
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NCT00248391 Unknown status N/A The Influence of Feeding Position on Pulmonary Morbidity in Young Children January 2008
NCT03478150 Unknown status N/A Evaluation of the Antibacterial Effect of Laser Diode and Zinc Oxide Nano Particles in Cavity Disinfection April 1, 2018 February 28, 2019
NCT02151916 Unknown status Phase 3 Preventing Early Childhood Caries in Indigenous Children: the Baby Teeth Talk Study June 2011 July 2016
NCT03488056 Unknown status N/A Effectiveness of ICCMS in Reducing the Incidence of Dental Caries in Children November 16, 2017 December 2021
NCT02232828 Unknown status N/A Selective or Stepwise Removal of Deep Caries October 2014 June 2018
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NCT04854655 Unknown status N/A Evaluation of Ion Releasing Hybrid Restorative Material October 10, 2021 October 30, 2022
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NCT03556865 Unknown status Knowledge, Attitude, And Practice In A Group Of Egyptian Dentists Towards Preventive Measures In Pediatric Dentistry: A Cross-Sectional Study July 2018 October 2018
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NCT02312921 Unknown status Population-centered Risk- and Evidence-based Dental Inter-professional Care Team January 2016 June 2019
NCT02327507 Unknown status Everybody Brush: A Community-wide Toothpaste Distribution Campaign June 2014 July 2016
NCT03566953 Unknown status Dietary Influences On Caries Index Among Sudanese And Egyptian Adult Population November 1, 2018 June 30, 2019
NCT02341352 Unknown status Phase 3 Three Measures for the Prevention of Carious Lesions in Preschool Children April 2013 June 2015
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NCT03598972 Unknown status the Effect of Prenatal Vitamins on the Tooth Structure June 15, 2021 July 15, 2021
NCT03609034 Unknown status Knowledge, Attitude and Practice of a Group of Egyptian Dental Interns Toward Caries Risk Assessment September 2018 November 2019
NCT00867542 Unknown status Dental and Oral Finding in Israeli Children With Past Intrauterine Growth Retardation (IUGR) June 2009 February 2010
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NCT03685058 Unknown status N/A Effect of Light Curable Resin Modified Glass Ionomer Varnish on Non-Cavitated Proximal Carious Lesions' Progression January 11, 2018 November 2019
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NCT03700840 Unknown status N/A Interdental Microbiota Among Adolescents November 2018 December 31, 2018
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NCT03732040 Unknown status N/A Miswak Versus Standard Measures to Prevent the Incidence of Caries Young Egyptian Adults: A Randomized Controlled Clinical Trial January 1, 2019 March 1, 2022
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NCT00435500 Unknown status Phase 3 Fluoride Varnish in the Prevention of Dental Caries in Aboriginal and Non-aboriginal Children June 2003 January 2006
NCT04992754 Unknown status Oral Health and Pregnancy July 20, 2021 June 1, 2022
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NCT04329858 Unknown status N/A the Antibacterial Effect of Zinc ,Silver and Fluoride July 15, 2021 July 15, 2021
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NCT04330794 Unknown status N/A the NMFACT Caries Index January 15, 2021 January 15, 2022
NCT04341636 Unknown status Phase 4 A Comparison of the Accurate Diagnosis of the Horizontal & Vertical Bitewing Images April 2020 February 2021
NCT04355000 Unknown status N/A Comparative Evaluation of Effectiveness of Hall Technique and Resin Modified Glass Ionomer Cement in Controlling Occlusoproximal Caries in Primary Molars in Children November 1, 2019 November 2020
NCT04357093 Unknown status N/A Remineralizing Efficacy of Grape Seed Extract in Management of White Spot Lesion in Post Orthodontic Treated Patients. February 2021 September 2021
NCT02969538 Unknown status N/A Effect of Shortening the Etching Time on the Clinical Performance of Resin Composite Restorations in Primary Teeth November 2016 November 2017
NCT05437432 Unknown status N/A Esthetic Evaluation of Onlay Restorations Constructed From Vita Ambria Glass Ceramics March 1, 2022 June 1, 2023
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NCT01062633 Unknown status Phase 2/Phase 3 Effect of Erythritol and Xylitol on Dental Caries Prevention in Children January 2008 November 2011
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NCT02798809 Unknown status GENOA ORAL GROWTH LONGITUDINAL STUDY (GeOrGS) April 1, 2012 January 1, 2020
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NCT05403008 Unknown status N/A Clinical Performance and Wear Resistance of Highly Translucent Nano Zirconia Reinforced Glass Ionomer Filling Versus Conventional Resin Composite Restorations in Patients With Proximal Carious Teeth. (A One-year Randomized Clinical Trial). June 2022 February 2023
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NCT05409625 Unknown status N/A 3D Scanning and Transillumination vs Conventional Examination to Assess Caries Progression, Stability or Regression October 15, 2021 December 2022
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NCT00268138 Unknown status Phase 4 Elmex Gel Efficacy in Preventing White Spot Lesions April 2006 December 2010
NCT02708160 Withdrawn Phase 2 Assessment of Prevident Sodium Fluoride 1.1% Toothpaste Using an Intra-oral Remineralization-demineralization Model March 2016 June 2016
NCT04001153 Withdrawn Occlusal Compensation After the Hall Technique July 10, 2019 July 31, 2020
NCT03785769 Withdrawn N/A Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement January 1, 2022 December 1, 2024
NCT02436473 Withdrawn N/A Clinical Efficacy of Fluoride Toothpastes Using an In Situ Caries Model December 2015 November 2016
NCT03089567 Withdrawn Early Phase 1 Comparison of the Salivary Levels of Streptococcus Mutans in Pediatric Patients With Early Childhood Caries After the Application of Silver Diamine Fluoride or 5% Sodium Fluoride Varnish September 15, 2017 January 15, 2018
NCT03389373 Withdrawn N/A Microbial Testing for Caries Risk Assessment February 1, 2018 July 1, 2018
NCT01224002 Withdrawn A Comparative Feasibility Study to Assess the Prevalence and Severity of Dental Caries in Incarcerated People Who Abuse Methamphetamine September 2010 November 2012
NCT02388178 Withdrawn Phase 2 To Determine the Ability of a New Product Formulation to Remineralize an Early Caries Lesion by an In-situ Study April 2015 July 2015
NCT03575494 Withdrawn Relationship Between Oral Health Status and Unexplained Female Infertility in Turkish Population April 15, 2018 February 15, 2020
NCT01424852 Withdrawn N/A Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child January 2012 December 2012
Disase is a (Disease Ontology)
DOID:214
Cross Reference ID (Disease Ontology)
EFO:0003819
Cross Reference ID (Disease Ontology)
ICD10CM:K02
Cross Reference ID (Disease Ontology)
ICD10CM:K02.6
Cross Reference ID (Disease Ontology)
ICD9CM:521.0
Cross Reference ID (Disease Ontology)
ICD9CM:521.07
Cross Reference ID (Disease Ontology)
MESH:D003731
Cross Reference ID (Disease Ontology)
NCI:C52593
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:155632007
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0011334
Cross Reference ID (Disease Ontology)
UMLS_CUI:C1456145
Exact Synonym (Disease Ontology)
Dental caries extending into pulp
Exact Synonym (Disease Ontology)
Dental caries of smooth surface
Exact Synonym (Disease Ontology)
Dental caries pit and fissure
ICD10 preferred id (Insert disease from ICD10)
D0008511
ICD10 class code (Insert disease from ICD10)
K02
MeSH unique ID (MeSH (Medical Subject Headings))
D003731