tuberculosis

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Information
Disease name
tuberculosis
Disease ID
DOID:399
Description
"A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes." [url:https\://www.merckmanuals.com/home/infections/tuberculosis-and-related-infections/tuberculosis-tb]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03934931 Active, not recruiting N/A Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial) July 13, 2020 November 8, 2024
NCT04568954 Active, not recruiting N/A TB-CAPT CORE Truenat Trial August 28, 2022 April 30, 2024
NCT03915366 Active, not recruiting Phase 2/Phase 3 Empirical Treatment Against Cytomegalovirus and Tuberculosis in HIV-infected Infants With Severe Pneumonia March 1, 2020 July 31, 2025
NCT04947475 Active, not recruiting N/A Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community January 1, 2017 July 31, 2024
NCT04166474 Active, not recruiting Phase 4 Drug Interactions Between Dolutegravir and Escalating Doses of Rifampicin November 18, 2021 April 2024
NCT03912207 Active, not recruiting Phase 1 Investigating Immune Responses to Aerosol BCG Challenge in Healthy UK Adults April 19, 2019 June 2024
NCT03896685 Active, not recruiting Phase 3 Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) April 6, 2020 November 2024
NCT03598842 Active, not recruiting N/A Tuberculosis - Learning the Impact of Nutrition July 12, 2019 December 2025
NCT06021041 Active, not recruiting A Retrospective Study on the Treatment Pattern and Clinical Prognosis of Severe Tuberculosis Patients January 13, 2018 February 1, 2024
NCT03100786 Active, not recruiting Phase 3 Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis February 8, 2018 June 30, 2024
NCT04567368 Active, not recruiting TB-CAPT MTB/XDR Study May 14, 2021 June 30, 2024
NCT06438978 Active, not recruiting Phase 1 Tuberculosis Vaccine in Healthy Indian Adults January 19, 2024 August 2024
NCT06153069 Active, not recruiting Phase 4 Subclinical TB With Innovative Modified Short-course Regimens November 1, 2023 November 2027
NCT03089983 Active, not recruiting N/A Addiction, HIV and Tuberculosis in Malaysian Criminal Justice Settings August 21, 2017 May 2024
NCT04557176 Active, not recruiting N/A TB Screening Improves Preventive Therapy Uptake November 16, 2020 March 15, 2025
NCT04520113 Active, not recruiting N/A Kharituwe TB Contact Tracing Study September 1, 2020 June 2024
NCT04466488 Active, not recruiting N/A Prevent TB: Choice Architecture for TPT Delivery September 15, 2021 December 31, 2024
NCT03042754 Active, not recruiting N/A Improve Treatment Outcomes for Tuberculosis Infection in Tertiary Care Hospitals June 6, 2011 December 1, 2030
NCT04152161 Active, not recruiting Phase 2 Bacille Calmette Guerin (BCG) Revaccination of Healthy Adolescents for the Prevention of Mycobacterium Tuberculosis Sustained Infection October 16, 2019 September 1, 2025
NCT05329415 Active, not recruiting Tuberculosis Drug Levels and Continuous Glucose Monitoring in Diabetic Patients February 1, 2022 May 2024
NCT02906007 Active, not recruiting Phase 1/Phase 2 Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV September 21, 2017 August 15, 2025
NCT04311502 Active, not recruiting Phase 2 Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST Study June 16, 2021 June 23, 2024
NCT02715271 Active, not recruiting Study of TB Lesions Obtained in Therapeutical Surgery September 2016 July 2025
NCT04926922 Active, not recruiting PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia July 27, 2021 June 7, 2024
NCT04909385 Active, not recruiting TB PCR in BAL and EBUS-TBNA January 15, 2021 February 29, 2024
NCT04260477 Active, not recruiting Phase 3 Novel Triple-dose Tuberculosis Retreatment Regimen March 1, 2021 September 2025
NCT04121195 Active, not recruiting Phase 2/Phase 3 Dose Escalation Study to Determine the Pharmacokinetics of Atazanavir Administered With RIfampicin to HIV Positive Adults on sEcond-line ART Regimen With Suppressed HIV-1 Viral Load October 30, 2020 August 20, 2023
NCT04221789 Active, not recruiting N/A TB Treatment Support Tool Interactive Mobile App and Direct Adherence Monitoring on TB Treatment Outcomes November 17, 2020 June 1, 2024
NCT04825327 Active, not recruiting Predicting the Future: Incipient Tuberculosis April 21, 2021 September 30, 2025
NCT04062201 Active, not recruiting Phase 3 Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Care August 22, 2019 June 2023
NCT04781257 Active, not recruiting Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries March 1, 2021 April 30, 2024
NCT04703075 Active, not recruiting Phase 4 Ultra Curto (Ultra Short) TB Prevention Therapy March 24, 2022 December 31, 2024
NCT05724212 Active, not recruiting Evaluation of a CD4/CD8+ Interferon Gamma Release Assay for Monitoring Anti-Tuberculosis Treatment January 27, 2017 February 1, 2024
NCT05044910 Active, not recruiting The Impact of Malnutrition on Immune Responses to Tuberculosis August 1, 2020 December 1, 2024
NCT04179500 Active, not recruiting Phase 2 A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis Volunteers September 16, 2021 August 30, 2024
NCT01464762 Approved for marketing Early Access of TMC207 in Patients With Extensively Drug Resistant or Pre-XDR Pulmonary Tuberculosis
NCT00107887 Completed Phase 4 TB (Tuberculosis) Preventive Therapy for HIV Patients With Access to HAART (Highly Active Antiretroviral Therapy) June 2005 December 2010
NCT00108862 Completed Phase 4 Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis August 2006 July 2010
NCT00115609 Completed Phase 3 Efficacy of Tenofovir-Emtricitabine and Efavirenz in HIV Infected Patients With Tuberculosis (ANRS129) January 2006 November 2009
NCT00120510 Completed N/A Early Versus Standard Start of Anti-HIV Therapy for Treatment-Naive Adults in Haiti July 2007 September 2009
NCT00128206 Completed Phase 3 Treatment of Latent TB Infection for Jailed Persons November 2004 September 2009
NCT00129649 Completed N/A Service Development: Assessing Non-attendance Rates in Outpatient Clinics October 2005 November 2006
NCT00130247 Completed Phase 3 Tuberculosis Treatment Shortening Trial April 8, 2002 November 28, 2008
NCT00130325 Completed N/A A Trial of Isoniazid for the Reversion of Interferon Gamma ELISPOT in Tuberculosis (TB) Case Contacts October 2004 June 2009
NCT00134342 Completed Tuberculosis (TB) Screening for the Diagnosis of Latent TB in Immunocompromised Populations January 2005 April 2005
NCT00144417 Completed Phase 2 TBTC Study 28: Moxifloxacin Versus Isoniazid for TB Treatment February 2006 December 2007
NCT00146302 Completed Phase 4 Should Low Birth Weight Infants Be Vaccinated With BCG Vaccine at Birth in Developing Countries? November 2002 March 2008
NCT00149448 Completed Effectiveness of the TB Contact Priority Model May 2004 March 2009
NCT00157066 Completed N/A Effects of Vitamin D Supplementation on Antimycobacterial Immunity December 2002 September 2006
NCT00164281 Completed Phase 4 Study of Limited Versus Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-infected Persons in Botswana November 2004 May 2011
NCT00164450 Completed N/A TBTC Study 26 PK: Rifapentine Pharmacokinetics in Children During Treatment of Latent TB Infection September 2005 August 2008
NCT00164463 Completed Phase 2 TBTC Study 27/28 PK: Moxifloxacin Pharmacokinetics During TB Treatment July 2004 August 2007
NCT00170638 Completed Tuberculosis Immunity in Children April 2005 April 2010
NCT00173433 Completed Exogenous Reinfection of Tuberculosis in Taiwan August 2005 July 2006
NCT00192556 Completed N/A Food Incentives for TB Treatment Compliance in East Timor (FITTCET) March 2005 August 2006
NCT00197704 Completed Phase 3 Nutrition, Immunology and Epidemiology of Tuberculosis March 2000 May 2004
NCT00201123 Completed Phase 2 Effects of Interferon-Gamma on Cavitary Pulmonary Tuberculosis in the Lungs April 2005 August 2007
NCT00201253 Completed Expression of Tuberculosis in the Lung September 2000 June 2008
NCT00226434 Completed Phase 3 Early vs Late Introduction of Antiretroviral Therapy in HIV-infected Patients With Tuberculosis (ANRS 1295 CAMELIA) January 2006 May 2010
NCT00233168 Completed N/A Effectiveness of Public Health Model of Latent Tuberculosis Infection Control for High-Risk Adolescents September 2003 August 2008
NCT00265226 Completed Phase 3 Efficacy and Safety Study of Immunomodulator as an Adjunct Therapy in Pulmonary Tuberculosis (TB) Retreatment Patients March 2005 March 2011
NCT00266383 Completed The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population January 2005 December 2005
NCT00293228 Completed Phase 4 Treatment of Latent Tuberculosis Infection With Isoniazid February 2007 June 2009
NCT00306319 Completed Phase 2 Pharmacokinetic Interaction Study in Indonesian Tuberculosis Patients Indonesia January 2006 May 2006
NCT00311298 Completed Phase 3 Nutrition, Diabetes and Pulmonary TB/HIV April 2006 March 2009
NCT00317330 Completed Phase 3 A Randomized Trial of DOTS Versus Enhanced DOTS for Community Control of Tuberculosis December 2004 June 2005
NCT00330304 Completed Phase 3 Isoniazid Prophylaxis With Concomitant Cotrimoxazole in HIV-infected Children January 2003 November 15, 2011
NCT00341328 Completed Phase 3 Efficacy and Safety of Immunomodulator as an Adjunct Therapy in New Pulmonary Tuberculosis(Category I) Patients. March 2007 March 2012
NCT00341601 Completed Multi-Drug Resistant Tuberculosis in Korea January 3, 2005 January 29, 2018
NCT00346476 Completed Characteristics and Prevalence of Tuberculosis and HIV in Masiphumelele Township, Cape Town, South Africa April 2006 December 2010
NCT00351702 Completed Phase 3 Preventive Therapy for Tuberculosis in HIV Infected Persons February 2001 June 2011
NCT00395720 Completed Phase 1 The Safety and Immunogenicity of a TB Vaccine; MVA85A, in Healthy Volunteers Who Are Infected With HIV November 2006 July 2010
NCT00396084 Completed Phase 1/Phase 2 Early Bactericidal Activity of Linezolid, Gatifloxacin, Levofloxacin, Isoniazid (INH) and Moxifloxacin in HIV Negative Adults With Initial Episodes of Sputum Smear-Positive Pulmonary Tuberculosis February 10, 2004 December 28, 2007
NCT00396370 Completed Phase 1 BCG Vaccination Delivered Intradermally, Orally and by Combined Routes December 2, 2008 July 23, 2012
NCT00397943 Completed Phase 2 Safety and Immunogenicity of 2 Formulations of Tuberculosis Vaccine GSK692342 Given at 0,1 Months to Healthy Adults November 15, 2006 December 1, 2009
NCT00398996 Completed Phase 3 A Study to Compare Three Existing Starting Points of Anti-Retroviral Therapy (ART) Initiation in HIV/Tuberculosis (TB) Co-infected Patients June 2005 July 2010
NCT00402402 Completed Phase 4 Comparison of Quantiferon-TB Gold Assay With Tuberculin Skin Testing in Patients With Chronic Liver Disease October 2006 July 2007
NCT00402610 Completed Phase 4 A Randomized Trial of Three Regimens to Prevent Tuberculosis in HIV-Infected Patients With Anergy January 1994 December 1998
NCT00405301 Completed Phase 4 Study of Safety and Efficacy of Different Regimes of Reintroduction of Anti-TB Drugs in Anti-TB Drugs Induced Liver Damage December 2006 December 2008
NCT00411996 Completed Phase 1/Phase 2 The Pharmacokinetics and Safety of IDV/r With NRTIs in HIV/TB Co-infected Patients Receiving Rifampicin December 2006 December 2009
NCT00412009 Completed Phase 4 Investigation of a Novel Approach to Improve Treatment Success Rates for Tuberculosis Patients in Senegal May 2003 January 2005
NCT00423566 Completed Phase 1 A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers. September 2002 July 2003
NCT00423839 Completed Phase 1 A Phase I Study of the Safety and Immunogenicity of MVA85A in Healthy Gambian Volunteers March 2003 July 2005
NCT00425113 Completed Phase 2 Metronidazole for Pulmonary Tuberculosis (South Korea) December 2006 February 2013
NCT00427453 Completed Phase 1 A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Received BCG Immunisation 1 Month Previously June 2003 March 2005
NCT00427830 Completed Phase 1 A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Previously Received BCG May 2003 January 2005
NCT00449644 Completed Phase 2 TMC207-TiDP13-C208: Anti-bacterial Activity, Safety, and Tolerability of TMC207 in Participants With Multi-drug Resistant Mycobacterium Tuberculosis (MDR-TB). June 2007 October 2012
NCT00456183 Completed Phase 1 Safety and Immunogenicity of MVA85A in Volunteers Latently Infected With TB. August 2005 April 2007
NCT00460590 Completed Phase 1 Safety and Immunogenicity of MVA85A, in Healthy Volunteers in Cape Town October 2005 June 2008
NCT00463086 Completed N/A Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons November 2007 November 2011
NCT00465465 Completed Phase 1 A Study of 2 Doses of a New TB Vaccine, MVA85A, in Healthy Volunteers Previously Vaccinated With BCG October 2005 September 2007
NCT00472316 Completed Innovative Approaches to Tuberculosis Control May 2007 May 2011
NCT00476853 Completed Phase 2 Efficacy Safety Study Comparing 2 Doses of NVP After Initiating Rifampin-containing TB Therapy October 2005 December 2009
NCT00483054 Completed Phase 3 Efavirenz-based Versus Nevirapine-based Antiretroviral Therapy Among HIV-infected Patients Receiving Rifampin January 2007 December 2010
NCT00495326 Completed Phase 2/Phase 3 Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146 CARINEMO) December 2007 April 2011
NCT00495651 Completed Phase 3 Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO) March 2008 January 2015
NCT00523926 Completed Phase 2 TMC207-C202: Study to Evaluate Bactericidal Activity of Multiple Oral Doses of TMC207 in Subjects With Sputum-Smear Positive Tuberculosis May 2005 October 2005
NCT00541294 Completed Diagnosis of Tuberculosis Infection in HIV Co-infected Children January 15, 2008 February 22, 2011
NCT00546273 Completed Phase 1 Clinical Trial to Study 4 Different Doses of the Vaccine RUTI in Healthy Volunteers April 2007 June 2008
NCT00548444 Completed Phase 1 T-Cell Turnover Following Vaccination With MVA85A October 2007 January 2010
NCT00557765 Completed Use of a Gamma-IFN Assay in Contact Tracing for Tuberculosis in a Low-Incidence, High Immigration Area October 2004 January 2006
NCT00560521 Completed N/A Continuous Positive Airway Pressure on Tuberculosis Pleural Effusion March 2005 March 2007
NCT00564642 Completed N/A Investigation of the Effect of N Acetylcysteine Against Anti-Tuberculosis Drugs Induced Liver Toxicity November 2007 April 2009
NCT00595907 Completed Results of an Interferon-Gamma Release Assay After Treatment for Tuberculosis October 2004 July 2006
NCT00604617 Completed Interferon-Gamma Release Assays in Tuberculosis (TB) - HIV Co-infected Children January 26, 2009 August 21, 2012
NCT00617643 Completed Phase 4 Nevirapine Drug Levels in HIV Positive Patients Also Receiving Rifampicin for Tuberculosis May 2008 December 2010
NCT00621322 Completed Phase 2 Safety and Immunogenicity Study of GSK Biologicals Tuberculosis Vaccines (692342) to Healthy Adults April 3, 2008 April 3, 2009
NCT00640887 Completed Phase 2 Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa February 2009 October 2010
NCT00645697 Completed Intravitreal Bevacizumab in Recalcitrant Inflammatory Ocular Neovascularization January 2007 March 2008
NCT00647205 Completed Phase 4 Evaluation of 2 Interferon γ Assays in the Diagnosis of Latent Tuberculosis in HIV-infected Patients.ANRS EP 40 QUANTI SPOT January 2008 November 2010
NCT00651066 Completed Phase 2 Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in Vietnam June 2010 September 2012
NCT00653627 Completed Phase 1 A Study to Quantify Bacille Calmette Guerin (BCG) and Characterise the Immune Response After BCG Vaccination August 2007 April 2010
NCT00653770 Completed Phase 1 A Phase I Study to Assess the Safety and Immunogenicity of Tuberculosis (TB) Vaccine Candidates FP85A and MVA85A September 2007 January 2010
NCT00675961 Completed N/A Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, Russia January 2007 June 2011
NCT00679159 Completed Phase 2 A Study of MVA85A in Healthy Children and Infants February 2008 December 2009
NCT00698334 Completed Phase 3 Efficacy of Thrice Weekly Directly Observed Treatment, Short-course (DOTS) in HIV-associated Tuberculosis April 2006 April 2011
NCT00707317 Completed T Cell Interferon-gamma Release Assay (TIGRA) in Immunocompromised Individuals June 2008 May 2011
NCT00707967 Completed Phase 2 Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in HIV-positive Adults. June 30, 2008 May 27, 2009
NCT04134689 Completed N/A DOT Selfie: A Mobile Technology Intervention to Evaluate Treatment Adherence Among Tuberculosis Patients July 13, 2020 April 30, 2023
NCT00000638 Completed N/A Preventive Treatment Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection September 1999
NCT00000778 Completed Phase 1 A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and Levofloxacin
NCT00000785 Completed A Registry of Tuberculosis Cases in the CPCRA August 1992 June 1994
NCT00000796 Completed N/A A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients. October 1998
NCT00000950 Completed N/A Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis
NCT00000955 Completed N/A Two-Stage Tuberculin (PPD) Skin Testing in Individuals With Human Immunodeficiency Virus (HIV) Infection December 1992
NCT00000959 Completed N/A Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Suspected Latent Tuberculous Infection June 1996
NCT00001033 Completed Phase 3 The Treatment of Tuberculosis in HIV-Infected Patients July 1997
NCT00004276 Completed Phase 2 Phase II Placebo Controlled Study of Thalidomide in Patients With Mycobacterial and HIV Infections September 1990 June 1999
NCT00004736 Completed Phase 1 Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients With Tuberculosis
NCT00005379 Completed Tuberculosis in a Multiethnic Inner City Population August 1994 July 1999
NCT00005737 Completed Tuberculosis Prophylaxis in the Homeless--A Controlled Trial September 1995 August 1999
NCT00005738 Completed Promoting Adherence to TB Regimens in Latino Adolescents September 1995 August 2001
NCT00005739 Completed Behavioral Interventions for Control of TB September 1995 December 2015
NCT00005740 Completed TB Contact Investigation: Behavioral Intervention September 1995 August 2000
NCT00005741 Completed Indigenous Outreach Among Injection Drug Users to Treat and Control TB September 1995 August 2001
NCT00005742 Completed Behavioral Interventions for Control of Tuberculosis September 1995 August 2001
NCT00023348 Completed Phase 2/Phase 3 TBTC Study 23A: Pharmacokinetics of Intermittent Isoniazid and Rifabutin in HIV-TB July 1999 November 2002
NCT00023361 Completed N/A TBTC Study 23: Treatment of HIV-Related Tuberculosis Using a Rifabutin-Based Regimen February 1999 February 2003
NCT00023374 Completed N/A TBTC Study 24: Intermittent Treatment of TB With Isoniazid Resistance or Intolerance August 2000 December 2010
NCT00023387 Completed N/A TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine March 2000 May 2001
NCT00023400 Completed Phase 4 TBTC Study 23B:Intensive PK of the Nelfinavir Rifabutin Interaction in Patients With HIV-TB February 2000 February 2002
NCT00023413 Completed Phase 2 TBTC Study 23C: Pharmacokinetics of Intermittent Rifabutin and Isoniazid With Daily Efavirenz November 1999 February 2004
NCT00023426 Completed Phase 2 TBTC Study 25: Study of the Tolerability of Higher Doses of Rifapentine in the Treatment of Tuberculosis July 1999 February 2003
NCT00023439 Completed TBTC NAA Study: Pilot Study of Surrogate Markers for Outcome of TB Treatment May 2000
NCT00023452 Completed Phase 3 Three Months of Weekly Rifapentine and Isoniazid for M. Tuberculosis Infection June 2001 September 2013
NCT00052195 Completed Phase 2/Phase 3 Investigational Vaccine for the Prevention of Disseminated Tuberculosis in HIV Infected People September 2001 May 2009
NCT00054769 Completed Diagnosing Tuberculosis in HIV Infected Children in Peru March 2002 February 2007
NCT00057122 Completed Phase 3 Tuberculosis Prevention for HIV Infected Adults September 2002 June 2009
NCT00057421 Completed Phase 2 Tuberculosis in HIV Infected Patients in Uganda November 1998 September 2002
NCT00078247 Completed Phase 3 Anti-HIV Drugs for Ugandan Patients With HIV and Tuberculosis October 2004
NCT00082173 Completed Phase 2 Moxifloxacin As Part of a Multi-Drug Regimen For Tuberculosis October 2004 September 2008
NCT00091936 Completed N/A Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited Settings August 2009
NCT00096681 Completed Prevalence of HIV and Tuberculosis in Masiphumelele Township, Cape Town, South Africa February 2005 February 2006
NCT00096850 Completed N/A Safety, Tolerability, and Blood Levels of Ritonavir-Boosted Atazanavir and Rifampin When Taken Together in HIV Uninfected Adults December 2007
NCT01722396 Completed Phase 3 Pharmacogenetics of Vitamin D Supplementation in Tuberculosis March 2011 November 2012
NCT01742364 Completed N/A Comparative Study of Bacille Calmette Guerin (BCG) Delivery Via Disposable Syringe Jet Injector and Needle & Syringe December 2012 December 2013
NCT01748357 Completed Siemens VOC TB Pilot Study December 2012 December 2013
NCT01751568 Completed Phase 1/Phase 2 Safety, Tolerance and Pharmacokinetics of Raltegravir-Containing Antiretroviral Therapy in Infants, Children Infected With HIV and TB November 12, 2014 November 27, 2019
NCT01755598 Completed Phase 2 Study to Evaluate the Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine in Adults August 19, 2014 November 16, 2018
NCT01766830 Completed N/A Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever) January 2013 July 2016
NCT01768273 Completed Phase 1 Evaluation of the Pharmacokinetic Interaction Between PA-824 and Midazolam December 2009 April 2010
NCT01770730 Completed N/A A Trial of the Urine LAM Strip Test for TB Diagnosis Amongst Hospitalized HIV-infected Patients January 2013 January 2015
NCT01779102 Completed Phase 2/Phase 3 Safety Study Investigating if Concomitant Injections of C-Tb and 2 T.U Tuberculin Affect Induration Responses October 2013 September 2014
NCT01800487 Completed N/A The Efficacy of Silymarin on the Prevention of Hepatotoxicity From Antituberculosis Drugs January 2012 July 2013
NCT01811823 Completed Phase 4 Effect of HIV and/or Active Tuberculosis on the Immune Responses to Trivalent Influenza Vaccine (TIV) in Adults March 31, 2014 November 20, 2014
NCT01828827 Completed Phase 1 Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects March 2007 March 2007
NCT01829490 Completed Phase 1 Safety Study of ChAdOx1 85A Vaccination With and Without MVA85A Boost in Healthy Adults July 2013 April 2016
NCT01830439 Completed Phase 1 Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009) September 2009 January 2010
NCT01832987 Completed Phase 2 Pharmacokinetic Parameters of Co-trimoxazole October 2013 August 2014
NCT01841541 Completed N/A The Impact of Involving Informal Health Providers for Tuberculosis Control in Sudan January 2009 April 2012
NCT01850043 Completed The Epidemiology of TST Change in Korea May 2005 May 2012
NCT01861730 Completed Phase 1/Phase 2 Phase 1/II, Safety and Immunogenicity Study of AERAS-404 in BCG-Primed Infants July 1, 2013 December 22, 2017
NCT01864603 Completed N/A Sustainable East Africa Research in Community Health April 2013 April 2021
NCT01868464 Completed Phase 1 Challenge Model for Assessment of Human TB Immunity May 28, 2014 December 18, 2017
NCT01872390 Completed N/A Start TB Patients on ART and Retain on Treatment (START Study) April 2013 May 7, 2021
NCT01924286 Completed Phase 3 Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisone August 30, 2013 April 2017
NCT01926379 Completed N/A ENhance Initiation and Retention in Isoniazid Preventive Therapy (IPT) Care for HIV Study (ENRICH Study) July 2013 May 7, 2021
NCT01932268 Completed Phase 2 A Pilot Study for Pharmacokinetic Parameter of Colchicine in Patient Taking Rifampin January 2011 December 2011
NCT01934309 Completed N/A Clinical Decision-support Reminders to Improve IPT Initiation Among HIV Positive Adults in Western Kenya September 2013 August 2014
NCT01936831 Completed Phase 2 High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB) August 13, 2014 October 6, 2021
NCT01954563 Completed Phase 1 Study Evaluating Aerosol and Intradermal Administration of a Candidate Tuberculosis (TB) Vaccine, MVA85A, as a Way to Increase Immune Response and Avoid Anti-vector Immunity October 2013 January 2016
NCT01955824 Completed Phase 2/Phase 3 A Trial on Clinical Efficacy of 1% Versus 2% Lignocaine in Cough Suppression and Pain Relief in Patients Undergoing Flexible Bronchoscopy May 2014 November 2014
NCT01960257 Completed Phase 4 Wirelessly Observed Therapy in Comparison to Directly Observed Therapy for the Treatment of Tuberculosis October 25, 2013 January 31, 2017
NCT01977768 Completed Phase 3 TB Immunotherapy Trial With Heat-killed M. Vaccae March 2014 December 2018
NCT01979900 Completed Phase 3 Phase III Clinical Study of Efficacy and Safety of Vaccae™ to Prevent Tuberculosis October 2013 November 26, 2017
NCT01990274 Completed N/A The Utility of Intensified Case Finding Combined With a Package of Novel TB Diagnostics Using a Mobile Clinic in Africa October 2013 April 2015
NCT02013245 Completed Phase 1 Dose-Escalation Study to Evaluate the Safety and Immunogenicity of MTBVAC Vaccine in Comparison With BCG Vaccine. January 2013 November 2014
NCT02027480 Completed Antiretroviral Therapy and Inflammatory and Coagulation Biomarkers: iMACS Study March 2014 October 2015
NCT02043067 Completed Enhanced TB Screening to Determine the Prevalence and Incidence of TB in Patients With HIV October 2011 May 2013
NCT02043314 Completed Phase 1 A Bioequivalence Study of Two Different Dosages of Isoniazid Tablet Formulations in Human Healthy Volunteers October 2008 March 2009
NCT02045394 Completed Epidemiology and Diagnosis of Haemoptysis: a Multicenter Study June 2013
NCT02063555 Completed Phase 1 Phase I Trial of DAR-901 February 2014 June 2016
NCT02066428 Completed Phase 1 A Phase I Randomized Placebo-Controlled, Double-Blind Study to Evaluate Safety and Immunogenicity of AERAS-404 Administered as Different Amounts of Antigen and Adjuvant Combinations in HIV-Negative BCG-Vaccinated Adults Without Evidence of Tuberculosis Infection November 2007 May 2009
NCT02073240 Completed Evaluation of an Enhanced Tuberculosis Infection Control Intervention in Healthcare Facilities in Vietnam and Thailand February 17, 2014 November 18, 2016
NCT02074956 Completed Phase 1 A Phase I Study to Evaluate Safety and Immunogenicity of AERAS 404 Administered in Adults May 2008 October 2009
NCT02075203 Completed Phase 2 Evaluation of Safety, Immunogenicity, and Prevention of TB With AERAS-404 and BCG Revaccination in Healthy Adolescents February 2014 October 6, 2017
NCT02076139 Completed N/A Safety and Immunogenicity of Nyaditum Resae® Probiotic to Protect From Tuberculosis March 2014 July 2015
NCT02082340 Completed N/A Innovative Approach in Tuberculosis Care in Armenia March 2014 May 2015
NCT02088892 Completed N/A A Clinical Challenge Study of BCG in Healthy Volunteers March 2014 January 2015
NCT02097095 Completed Substudy of Protocol TB-018 (NCT01755598): Collection and Storage of Biological Samples for Evaluation of Correlates of TB (C-041-972) August 2014 November 30, 2016
NCT02109874 Completed Phase 1 A Phase I Study to Evaluate Safety and Immunogenicity of AERAS 404 (C-011-404) December 2008 September 2012
NCT02115854 Completed Labial Biopsy in Patients With Tuberculosis Disease December 2010
NCT02121314 Completed Phase 2 HRZE Fasted/Fed in Newly Diagnosed TB July 2013 June 2014
NCT02127983 Completed N/A Engaging Informal Health Care Providers on Case Detection and Treatment Initiation Rates for TB and HIV in Rural Malawi (Triage Plus) January 2009 December 2012
NCT02135289 Completed The Role of IGRA in Screening and Monitoring for TB During Anti TNF Therapy in Patients With IMID March 2012 July 31, 2019
NCT02142894 Completed Evaluation of the QuantiFERON-TB Test. May 27, 2014 March 28, 2016
NCT02156882 Completed Establishment of a Clinical Trial Unit in Mavalane, Maputo, in Mozambique June 2014 September 2016
NCT02169141 Completed Pharmacokinetics of Levofloxacin and Capreomycin in Multidrug-Resistant Tuberculosis Patients November 2012 November 2013
NCT02170441 Completed Global Consortium for Drug-resistant Tuberculosis Diagnostics April 2012 June 2014
NCT02176772 Completed Iron Absorption and Utilization During Tuberculosis and After Treatment April 2015 January 2017
NCT02178748 Completed Phase 2 Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescents June 2014 January 2015
NCT02193776 Completed Phase 2 A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis. October 23, 2014 February 7, 2018
NCT02216331 Completed Phase 1 PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002) March 2010 May 2010
NCT02231229 Completed Phase 4 Rapid Detection of Rifampin and Isoniazid Resistance by PCR Before Tuberculosis (TB) Treatment Initiation July 23, 2014 February 18, 2020
NCT02234908 Completed N/A Rewards for Tuberculosis Contact Screening October 2014 December 2016
NCT02236078 Completed Phase 1 Brief Bactericidal Activity of Anti-Tuberculosis Drugs November 2015 September 30, 2020
NCT02238405 Completed N/A A Controlled Smoking Cessation Trial and Prospective Cohort Study of Tuberculosis (TB) Treatment Outcomes May 25, 2015 January 2018
NCT02251327 Completed Feasibility and Accuracy of a Novel Xpert Cartridge June 4, 2014 December 2015
NCT02252198 Completed Evaluation of Non-Inferiority of Two Fast Follower Nucleic Acid Amplification Tests February 2014 January 2015
NCT02253537 Completed Evaluation of the QuantiFERON-TB Test. February 2, 2015 April 26, 2016
NCT02256839 Completed Evaluation of the QuantiFERON-TB Test. October 2014 October 2015
NCT02273765 Completed Phase 3 Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis September 11, 2015 November 28, 2018
NCT02281643 Completed Phase 2 Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghana October 2014 March 15, 2017
NCT02288481 Completed Phase 1 A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult Subjects January 2015 June 2015
NCT02298309 Completed N/A Test and Treat TB: A Proof of Concept Trial in South Africa April 2015 November 2017
NCT02329730 Completed Phase 2 Phase IIa Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 February 2014 August 2014
NCT02336542 Completed Phase 2 Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 November 2014 July 2015
NCT02337270 Completed Phase 1 Phase 1 Clinical Trial of the Safety and Immunogenicity of an Adenovirus-based TB Vaccine Administered by Aerosol September 5, 2017 September 7, 2021
NCT02348177 Completed Phase 4 Pharmacokinetics of Lopinavir/Ritonavir Superboosting in Infants and Young Children Co-infected With HIV and TB January 2013 December 2016
NCT02375256 Completed Phase 1 A Leukapheresis Study for Immune Responses in Healthy US Adults Who Receive BCG Vaccination Followed by Boosting With AERAS-402 October 2009 December 2013
NCT02375698 Completed Phase 1 A Phase I Study of Safety & Immunogenicity of AERAS-456 in HIV-Neg. Adults Treated for Drug-susceptible Pulmonary TB November 21, 2014 October 24, 2016
NCT02378207 Completed Phase 1 Safety and Immunogenicity Study of BCG, H4:IC31, and H56:IC31 Revaccination in Healthy Adolescents May 2015 December 9, 2016
NCT02380508 Completed N/A Heterologous Effects of BCG in Healthy UK Adults February 2015 November 2016
NCT02382107 Completed A Blinded, Cross-sectional, Diagnostic Evaluation Study Performed in Pulmonary TB Suspects at the TB Dispensary for Sector 4 of the Marius-Nasta-Institute in Bucharest, Romania March 2015 August 2017
NCT02383849 Completed IMPAACT P1106: Pharmacokinetic Characteristics of Antiretrovirals and Tuberculosis Medicines in Low Birth Weight Infants August 4, 2015 February 14, 2020
NCT02389322 Completed Phase 2 Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65 March 2015 September 2015
NCT02391415 Completed Phase 2 Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa June 2015 November 2017
NCT02393586 Completed Phase 1 Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Faropenem Plus Amoxicillin/Clavulanic Acid in Healthy Volunteers February 2015 October 2015
NCT02410772 Completed Phase 3 TBTC Study 31: Rifapentine-containing Tuberculosis Treatment Shortening Regimens January 25, 2016 May 2021
NCT02412436 Completed Phase 2 PK Study of Rifampicin Interactions With DMPA and Efavirenz in TB November 3, 2015 June 15, 2017
NCT02413502 Completed Early Phase 1 Leukapheresis Sampling for Immune Responses After BCG Vaccination in BCG-naïve Healthy Adults in the US May 2015 October 2015
NCT02414828 Completed Phase 2 A Study to Evaluate the Safety of AERAS-402 in Adults Recently Treated for Pulmonary TB October 2008 November 2010
NCT02415985 Completed Phase 2 Pharmacokinetics and Safety of Rifabutin 150 mg Once Daily Versus Rifabutin 300 mg Thrice Weekly June 2015 December 2019
NCT02420444 Completed Phase 1 A Study for Safety and Immunogenicity of BCG and AERAS-404 in HIV-Negative, TB-Negative, BCG-Naive Adults January 2011 November 2013
NCT02430259 Completed Phase 3 Efficacy of Weekly Rifapentine and Isoniazid for Tuberculosis Prevention March 2015 June 2018
NCT02430506 Completed Phase 1 A Study to Evaluate Safety and Immunogenicity of AERAS-402 Administered in HIV-negative, BCG-vaccinated, QFT (+) and (-) Adults Without Evidence of TB September 2008 July 2010
NCT02454205 Completed Phase 2/Phase 3 An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant Tuberculosis November 12, 2015 August 30, 2021
NCT02457208 Completed Phase 1 PK Study of Anti-TB Drugs July 7, 2015 January 14, 2018
NCT02500277 Completed N/A Yield of Cryoprobe vs Flexible Forceps Pleural Biopsy January 2015 July 2018
NCT02501421 Completed Phase 1 Reactogenicity, Safety and Immunogenicity of a TB/FLU-04L Tuberculosis Vaccine October 2013 February 2015
NCT02503839 Completed Phase 1 Therapeutic Vaccination and Immune Modulation - New Treatment Strategies for the MDR Tuberculosis Pandemic November 2015 March 23, 2020
NCT02508376 Completed Phase 1 Safety, Tolerability, and Immunogenicity of the Vaccine Candidates ID93 + AP10-602 and ID93 + GLA-SE Administered Intramuscularly in Healthy Adult Subjects October 22, 2015 August 31, 2017
NCT02512939 Completed N/A Predictive Values of Next Generation Interferon Gamma Release Assays for Latent Tuberculosis Infection July 2015 November 30, 2016
NCT02520973 Completed N/A Screening for TB in Pregnancy. on HIV-Infected Pregnant Women May 2015 June 30, 2017
NCT02533089 Completed N/A Training Lay Healthcare Workers to Optimize TB Care and Improve Outcomes in Malawi May 2016 February 2018
NCT02534727 Completed Sputum Pharmacokinetics of TB Drugs and Bacterial Drug Resistance January 27, 2016 December 31, 2020
NCT02536768 Completed N/A Evaluation of South Africa's National Adherence Strategy September 2015 April 30, 2018
NCT02538952 Completed Phase 4 Evaluating Accuracy, Impact, and Operational Challenges of GeneXpert Use for TB Case Finding Among HIV-infected Persons August 1, 2012 July 1, 2017
NCT02581579 Completed N/A Study to Evaluate the Tolerability and Immunogenicity of Nyaditum Resae ® Probiotic Administered to Pediatric Population in Contact With Tuberculosis With or Without Latent Tuberculosis Infection December 9, 2015 March 6, 2019
NCT02583048 Completed Phase 2 Evaluating the Safety, Tolerability, and Pharmacokinetics of Bedaquiline and Delamanid, Alone and in Combination, For Drug-Resistant Pulmonary Tuberculosis August 15, 2016 February 4, 2021
NCT02596087 Completed N/A Improving Quality by Maintaining Accurate Problems in the EHR April 2016
NCT02602509 Completed Phase 1 Evaluating Celecoxib Activity in Mycobacterium Tuberculosis: A Whole Blood Bactericidal Activity Study in Healthy Volunteers November 2015 February 2016
NCT02613169 Completed Phase 2 Infant TB Infection Prevention Study August 2016 December 2020
NCT02619240 Completed Application of GeneXpert on Bronchoscopic Samples in the Clinical Management of Patients Suspicious of TB October 2015 August 30, 2017
NCT02623556 Completed Phase 3 Clinical Study of Recombinant Mycobacterium Tuberculosis ESAT6-CFP10 Allergen December 2015 March 2018
NCT02641106 Completed N/A VDOT for Monitoring Adherence to LTBI Treatment March 8, 2016 June 30, 2020
NCT02651259 Completed Phase 1/Phase 2 Evaluating PK, Tolerability, and Safety of Rifapentine and Isoniazid in Pregnant and Postpartum Women March 13, 2017 April 10, 2019
NCT02654613 Completed N/A Scaling up TB and HIV Treatment Integration June 1, 2015 December 30, 2020
NCT02662829 Completed N/A Preventing Childhood Tuberculosis in Lesotho (PREVENT Study) December 2015 January 2019
NCT02680470 Completed N/A Virtual Observed Therapy for Patients With Tuberculosis August 2015 May 2017
NCT02681445 Completed Non-invasive TB Triage and Patient Mapping Platform Using Breath Via Low-Cost Titanium Dioxide Nanotube Sensor February 2016 November 2017
NCT02684240 Completed Phase 2 A 14 Day Early Bactericidal Activity Study of Nitazoxanide for the Treatment of Tuberculosis February 2016 April 11, 2018
NCT02687529 Completed Evaluation of the 4th Generation QuantiFERON-TB Test (QFT-Plus) for the Detection of Tuberculosis Infection October 27, 2015 May 26, 2016
NCT02689089 Completed Phase 4 Taima TB: 3HP Study November 28, 2016 August 15, 2019
NCT02700347 Completed Phase 1 Whole Blood Bactericidal Activity Against Mycobacterium Tuberculosis of Pyrazinamide Plus Allopurinol in Healthy Volunteers February 2016 April 2016
NCT02701439 Completed SMF to Improve Performance of Microscopy for the Diagnosis of PTB in a High HIV Prevalence Setting September 2012 June 2014
NCT02709278 Completed Phase 1 Aerosol BCG Challenge Trial in Healthy UK Adults March 7, 2016 May 9, 2019
NCT02712424 Completed Phase 2 DAR-901 TB Booster Vaccine to Prevent TB in Adolescents March 2016 February 1, 2020
NCT02729532 Completed Effect of Xpert MTB/RIF on Patient Outcomes June 22, 2016 February 9, 2018
NCT02729571 Completed Phase 1/Phase 2 Dose-escalation Safety and Immunogenicity Study to Compare MTBVAC to BCG in Newborns With a Safety Arm in Adults September 2015 March 2018
NCT02744469 Completed Benin Population Diversity of Tuberculosis and Implications April 12, 2016 December 12, 2019
NCT02774993 Completed Phase 2 Doxycycline in Human Pulmonary Tuberculosis September 2015 June 2017
NCT02778828 Completed N/A Pharmacokinetic and Therapeutic Adaptation of Linezolid in the Treatment of Multi-Resistant Tuberculosis November 4, 2015 December 31, 2018
NCT02781909 Completed Phase 2 Potential Efficacy and Safety of Using Adjunctive Ibuprofen for XDR-TB Tuberculosis September 2016 January 2019
NCT02795260 Completed Phase 3 Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65(III-healthy) May 2016 October 2016
NCT02808507 Completed N/A Comparative Effectiveness/Implementation of TB Case Finding in Rural South Africa July 18, 2016 January 30, 2020
NCT02840877 Completed N/A The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes May 16, 2017 October 12, 2023
NCT02861768 Completed N/A Improving the Diagnostic of Tuberculosis March 22, 2013 February 8, 2019
NCT02874716 Completed N/A Quality of Tuberculosis Care in Urban Patna, India January 2015 December 2016
NCT02874755 Completed N/A Quality of Tuberculosis Care in Mumbai, India January 2015 March 10, 2017
NCT02875574 Completed Improving the Management of Drug Resistant Tuberculosis in the UK November 2016 December 2017
NCT02933281 Completed Phase 1/Phase 2 MTBVAC Study in Adults With and Without Latent Tuberculosis Infection in South Africa May 14, 2018 September 5, 2021
NCT02946762 Completed N/A TasP in Correctional Facilities February 1, 2016 March 31, 2018
NCT02953847 Completed Phase 1 The Bioavailability of Rifampicin in (FDCs) Widely Used in South Africa to Treat Drug-susceptible (TB) November 2016 February 2017
NCT02978131 Completed Histopathological Techniques and PCR on Tissues Included in Paraffin for the Diagnosis of Tuberculosis May 2015 June 2017
NCT02980016 Completed Phase 3 Evaluation of the Effect of 3HP vs Periodic 3HP vs 6H in HIV-Positive Individuals November 2016 October 18, 2019
NCT03017378 Completed Phase 1 Reactogenicity, Safety and Immunogenicity of a TB/FLU-01L Tuberculosis Vaccine October 2013 February 2015
NCT03026972 Completed Phase 1 A Phase ⅠStudy of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried April 16, 2018 October 30, 2019
NCT03032367 Completed Early Phase 1 TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study) November 10, 2016 January 11, 2017
NCT03036163 Completed Phase 1 Phase 1 Study of PBTZ169 January 2016 November 2016
NCT03074799 Completed N/A Nurse-Led, Symptom-Based Screening of Household Child Contacts of Tuberculosis Index Cases October 1, 2015 September 15, 2018
NCT03075410 Completed Phase 1 First Time in Human (FTIH) Safety and Pharmacokinetics (PK) Study of GSK3036656 in Healthy Subjects April 2, 2017 August 4, 2017
NCT03080012 Completed Salivary Therapeutic Drug Monitoring of Anti-Tuberculosis Drugs March 7, 2017 May 2, 2018
NCT03086486 Completed Phase 3 Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis November 21, 2017 February 8, 2022
NCT03092817 Completed Phase 3 Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial) May 25, 2017 April 26, 2023
NCT03106727 Completed N/A Evaluating the Impact of a Community Health Worker Program in Neno, Malawi March 1, 2017 July 31, 2019
NCT03135366 Completed N/A Self-verification and Support Via Mobile Phones Drastically Improves Tuberculosis Treatment Success in LMIC Settings January 4, 2016 April 14, 2017
NCT03137875 Completed Evaluation of PCR Using DNA Extract From Slides and Filter Paper for the Detection of Tuberculosis and MDR-tuberculosis March 2011 December 2012
NCT03154320 Completed N/A A Trial of Same-Day Testing and Treatment to Improve Outcomes Among Symptomatic Patients Newly Diagnosed With HIV November 6, 2017 April 16, 2021
NCT03168945 Completed N/A Xpert Active Case-finding Trial 2: Community-based Active Case-finding for Tuberculosis in South Africa November 2016 August 2020
NCT03175380 Completed Early Phase 1 Biological Samples Obtained by Leukapheresis Induced by Two BCG Vaccinations in BCG-naïve Healthy Adults in the US August 8, 2017 January 10, 2019
NCT03199313 Completed Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid September 26, 2017 December 16, 2017
NCT03199339 Completed Phase 1 A Phase 1 Study to Evaluate Safety, Tolerability, PK, and PK Interactions of TBA-7371 August 29, 2017 July 8, 2018
NCT03202693 Completed Phase 1 A Study of the Safety, Tolerability, and Absorption, Metabolism, and Excretion of PA-824 in Healthy Adult Male Subjects. March 2006 May 2006
NCT03211208 Completed Assessing Antibiotic Induced Liver Injury for Stratification of Tuberculosis Patients May 22, 2017 March 22, 2020
NCT03230409 Completed N/A Impact of Nursing Interventions on Adherence to Treatment With Anti-tuberculosis Drugs in Children and Adolescents January 1, 2014 January 15, 2017
NCT03255278 Completed Phase 1 Evaluation of the Safety and Immunogenicity of the Recombinant Subunit Vaccine "GamTBvac" Against the Tuberculosis. January 15, 2017 December 13, 2017
NCT03266003 Completed N/A An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment July 19, 2017 December 31, 2020
NCT03302299 Completed Phase 4 Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT) April 7, 2017 April 1, 2021
NCT03305991 Completed Tuberculosis Infection in Women of Reproductive Age and Their Infants December 1, 2015 March 12, 2024
NCT03315962 Completed N/A Simplified Isoniazid Preventive Therapy Strategy to Reduce TB Burden November 15, 2017 November 30, 2023
NCT03338621 Completed Phase 2/Phase 3 Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients July 30, 2018 June 10, 2022
NCT03356925 Completed N/A Improving TB Diagnosis and Treatment Through Basic, Applied and Health Systems Research February 6, 2018 June 30, 2022
NCT03423030 Completed Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulation December 5, 2017 March 28, 2018
NCT03456102 Completed Phase 2 Statin Adjunctive Therapy for TB March 9, 2020 August 31, 2022
NCT03458338 Completed Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa December 8, 2010 May 30, 2011
NCT03492216 Completed N/A Drinkers' Intervention to Prevent Tuberculosis (DIPT Study) April 16, 2018 August 2, 2022
NCT03497195 Completed N/A Achieving Tuberculosis (TB) Control In Zambia July 1, 2017 December 31, 2018
NCT03536117 Completed Phase 2 Dose-Defining Safety and Immunogenicity Study of MTBVAC in South African Neonates February 12, 2019 May 19, 2022
NCT03537170 Completed Dietary Assessment and Prevalence of Refeeding Syndrome in High-risk TB Patients in Chhattisgarh, India November 23, 2017 February 14, 2018
NCT03544476 Completed N/A Mobile Health Intervention for Active Tuberculosis April 9, 2019 July 31, 2020
NCT03545373 Completed Phase 3 Accuracy and Consequences of Using Trial-of-antibiotics for TB Diagnosis (ACT-TB Study) February 25, 2019 April 14, 2020
NCT03557281 Completed Phase 2 An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis March 22, 2019 December 14, 2021
NCT03559582 Completed Diagnostics and Pharmacotherapy for Severe Forms of TB (DMID 15-0100) April 28, 2016 January 31, 2021
NCT03590600 Completed Phase 1 A Single Ascending Dose Study of BTZ043 June 7, 2018 March 5, 2019
NCT03665402 Completed N/A A Pharamcogenomic Study for Isoniazid According to NAT2 Polymorphism Status May 13, 2018 March 31, 2019
NCT03667742 Completed Diagnosing of Acute Tuberculosis November 17, 2017 November 4, 2020
NCT03734172 Completed Rapid and Accurate Diagnosis of Paediatric TB (RaPaed-AIDA-TB) January 21, 2019 December 31, 2022
NCT03736278 Completed Characteristics of Tuberculosis Infection in Rheumatic Disease November 10, 2018 September 24, 2019
NCT03758612 Completed Phase 1 A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults January 16, 2019 March 14, 2020
NCT03767946 Completed Epidemiological Study In Tuberculosis-Endemic Urban Area in Senegal July 27, 2018 July 27, 2022
NCT03787914 Completed N/A Effect of Community Mobile Outreach Approach Compared to Facility Based Directly Observed Treatment Short Course on Treatment Outcome Among Tuberculosis Patients in Jeddah: A Randomized Controlled Trial November 1, 2017 November 1, 2018
NCT03794284 Completed Multiplex PCR -Microarray-based Assay in the Detection of Mycobacterium February 28, 2019 July 31, 2022
NCT03802812 Completed N/A Thin Bronchoscope and Virtual Bronchoscopic Navigation System for Tuberculosis February 1, 2019 April 19, 2022
NCT03808597 Completed N/A Digital Health Promotion in Iringa, Tanzania April 1, 2019 June 1, 2020
NCT03819114 Completed Phase 2 Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy May 6, 2019 November 30, 2020
NCT03819374 Completed Improving HIV/Tuberculosis Outcomes in Irkutsk April 15, 2018 April 30, 2021
NCT03822156 Completed Clinical Analysis of the Patients With Cavitary Pulmonary TB and Endobronchial TB in the PPM-UUH Cohort January 1, 2010 June 30, 2018
NCT03831906 Completed N/A Impact of Systematic Early Tuberculosis Detection Using Xpert MTB/RIF Ultra in Children With Severe Pneumonia in High Tuberculosis Burden Countries (TB-Speed Pneumonia) March 20, 2019 June 30, 2021
NCT03832023 Completed N/A Community-based Tuberculosis Tracing and Preventive Therapy October 14, 2019 August 1, 2022
NCT03851588 Completed Phase 2 Standard Versus Double Dose Dolutegravir in Patients With HIV-associated Tuberculosis December 19, 2019 June 28, 2022
NCT03862261 Completed N/A Integrating Pediatric TB Services Into Child Healthcare Services in Africa May 10, 2019 December 31, 2021
NCT03870061 Completed N/A Evaluation of an Infant Immunization Encouragement Program in Nigeria July 1, 2018 February 20, 2020
NCT03881228 Completed N/A Patient Centered Intervention to Prevent Tuberculosis Among Children Under Five Years Old December 1, 2019 August 15, 2023
NCT03882177 Completed Phase 2 StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosis February 21, 2020 December 31, 2022
NCT03891901 Completed Phase 2 A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin October 27, 2020 August 30, 2022
NCT03919812 Completed N/A Immunomodulatory Vitamin D in Thalassemia April 1, 2018 August 15, 2018
NCT03923231 Completed Pharmacokinetics of Atazanavir in Special Populations September 2, 2019 November 30, 2022
NCT03927664 Completed Clinico-radiological Classification of Peritoneal Tuberculosis May 1, 2019 July 30, 2020
NCT03947138 Completed Phase 3 A Study of GC3107(BCG Vaccine) in Healthy Infants August 6, 2019 September 6, 2022
NCT03948698 Completed TB Innovation Project: A Pre- and Post- Implementation Assessment (TIPPI) December 1, 2018 September 30, 2021
NCT03973970 Completed Assessing the Ability of the T-SPOT®.TB Test (IQ) September 23, 2019 June 30, 2020
NCT03982277 Completed Phase 2 Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy April 30, 2019 July 23, 2021
NCT03993093 Completed Prevalence of HIV +ve Cases With AIDS Defining Opportunistic Infections Among ART Naive Patients Attending ART Centre June 1, 2019 March 15, 2020
NCT04043390 Completed N/A A One-stop Shop for the Same Day Diagnosis and Management of TB and HIV January 21, 2019 December 31, 2020
NCT04064554 Completed N/A Clinical Study to Evaluate Safety and Immunogenicity of Bacillus Calmette-Guerin (BCG) Delivery Via Novel Micronjet600 Device Compared to Those Via Conventional Needle December 1, 2017 September 11, 2019
NCT04094350 Completed N/A Effect of Community Active Case Finding Strategies for Detection of Tuberculosis in Cambodia December 16, 2019 January 31, 2022
NCT04119375 Completed N/A Behavior Change and Digital Health Interventions for Improved TB Treatment Outcomes April 13, 2018 July 30, 2021
NCT04121494 Completed Early Phase 1 ChAdOx1 85A Aerosol Versus Intramuscular Vaccination in Healthy Adults (TB039) January 22, 2019 August 24, 2020
NCT00000636 Completed N/A Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection October 1997
NCT04141982 Completed Clinical Concordance Evaluation of T-SPOT®.TB Assay Performance (T-Cell SelectTM Study) November 4, 2019 March 18, 2020
NCT04147676 Completed Evaluation of Centralised TB Assay Solutions May 20, 2019 September 1, 2023
NCT04179344 Completed Usability Study of IeHS in Indonesia August 5, 2019 October 31, 2019
NCT04187313 Completed N/A Increasing Notifications of Tuberculosis From Private Practitioners July 1, 2020 August 31, 2022
NCT04203628 Completed N/A Evaluation of Four Stool Processing Methods Combined With Xpert MTB/RIF Ultra for Diagnosis of Intrathoracic Paediatric TB (TB-Speed - Stool Processing) January 13, 2020 February 7, 2022
NCT04216420 Completed N/A Electronic Pillbox-enabled SAT Versus DOT for TB Medication Adherence and Treatment Outcomes June 1, 2020 August 31, 2021
NCT04239313 Completed Phase 1 A Phase Ib Study of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02) May 27, 2020 June 20, 2022
NCT04325438 Completed N/A The Impact of Pharmacists' Interventions on the Quality of Life of HIV-TB Co-infection Outpatients in Indonesia April 1, 2017 March 30, 2019
NCT04369326 Completed N/A Community Initiated Preventive Therapy for TB September 7, 2021 June 30, 2023
NCT04424264 Completed Phase 1 The Effect of Rifampicin on the Pharmacokinetics of Intracellular Tenofovir-diphosphate and Tenofovir When Coadministered With Tenofovir Alafenamide Fumarate During the Maintenance Phase of Tuberculosis Treatment in TB/HIV-1 Coinfected Participants December 5, 2019 October 30, 2020
NCT04463680 Completed Phase 4 Rifampin and the Contraceptive Implant September 23, 2020 February 22, 2022
NCT04466293 Completed N/A Choice Architecture Based TB Preventive Therapy Prescribing March 29, 2021 October 31, 2022
NCT04493671 Completed Phase 1 Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults June 8, 2020 November 15, 2022
NCT04525235 Completed Phase 1 Phenotyping of High Dose Rifampicin January 7, 2021 August 12, 2021
NCT04563273 Completed Phase 1 Clinical Study of BCG Vaccine for Intradermal Injection October 21, 2020 October 30, 2022
NCT04593524 Completed N/A The Role of Vitamin D, A, and Beta Carotene in Tuberculosis Patients With Vitamin D Receptor Gene Polymorphism May 14, 2019 September 22, 2019
NCT04593771 Completed Phase 1 Phase I Clinical Protocol of BCG-PPD in Healthy People October 21, 2020 May 24, 2021
NCT04613258 Completed N/A Soy, Catfish, Anchovy, and Rice Supplementation Increases 25(OH)D Serum Levels in Tuberculosis Patients With Complications May 11, 2019 September 17, 2019
NCT04629378 Completed Phase 2 Evaluating the EBA of Meropenem With Amoxicillin/Clavulanate and Pyrazinamide or Bedaquiline in Adults With PTB August 17, 2020 June 4, 2021
NCT04721795 Completed Phase 2/Phase 3 Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis) January 19, 2021 June 30, 2022
NCT04743583 Completed Prevalence and Malignant Involvement of Calcified Intrathoracic Lymph Nodes in Patients Undergoing Endosonography March 20, 2021 December 31, 2022
NCT04745897 Completed N/A Accessibility of the World Health Organization's eTB Catalogue of Recommendations February 26, 2021 August 29, 2021
NCT04826809 Completed N/A New Reusable Mask Design With Superior Filtration and Fit April 9, 2021 October 27, 2022
NCT04865536 Completed Phase 1 Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects February 16, 2021 March 25, 2022
NCT04871230 Completed Dried Blood Spot Test to Assess TB in Pregnancy October 27, 2021 September 30, 2022
NCT04874948 Completed Phase 1 Absorption, Elimination and Safety of 14C-labeled Radioactive BTZ-043, a New Compound in TB Treatment September 21, 2021 October 15, 2021
NCT04890535 Completed Phase 1 Evaluation of the Safety, Tolerability, PK of TBAJ-587 in Healthy Adults December 1, 2020 February 27, 2023
NCT04899076 Completed Stool Processing Kit (SPK) Evaluation for Pediatric Tuberculosis (TB) June 19, 2019 October 31, 2021
NCT04916899 Completed Safety of doTBal® in Patients With Tuberculosis: Conduction of an Intensive Pharmacovigilance Program November 2014 September 2016
NCT04938596 Completed N/A Airborne Preventive Measures to Reduce New TB Infections in Household Contacts October 4, 2021 March 30, 2024
NCT05100758 Completed N/A Active Hexose Correlated Compound in Tuberculosis-HIV (Human Immunodeficiency Virus) Infection October 1, 2018 December 1, 2020
NCT05124665 Completed N/A Interrupting HIV and TB Stigma in the Household in Uganda October 25, 2021 August 30, 2022
NCT05202431 Completed N/A The Effect of Telephone Follow-up and Training on Treatment Adherence in Tuberculosis Patients and Contacts July 1, 2018 July 30, 2019
NCT05203068 Completed N/A Specificity Trial of the Recombinant Tuberculosis Allergen in BCG Vaccinated Healthy Volunteers November 24, 2021 January 26, 2022
NCT05282173 Completed N/A Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa June 8, 2022 August 1, 2023
NCT05283967 Completed Urine Colorimetry for Tuberculosis Pharmacokinetics Evaluation in Children and Adults January 1, 2019 December 1, 2023
NCT05337163 Completed A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China February 25, 2022 August 29, 2023
NCT05364593 Completed Evaluation of Point-of-care Ultrasound in Children From 6 Months to 15 Years With Presumptive Tuberculosis June 26, 2019 December 15, 2023
NCT05398562 Completed Phase 1 Tolerability and Reactogenicity Trial of the Recombinant Tuberculosis Allergen in Healthy Volunteers February 13, 2020 June 26, 2020
NCT05472051 Completed Health and Migration Trajectories of Housekeepers in Bamako February 28, 2022 June 22, 2023
NCT05526911 Completed Phase 1 A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults July 20, 2022 August 28, 2022
NCT05592223 Completed Phase 1 Phase I Open Label BCG Clinical Trial Assessing TB Drugs and Vaccines December 6, 2022 December 1, 2023
NCT05640648 Completed N/A Human-centered Design and Communities of Practice to Improve Delivery of Home-based Tuberculosis Contact Investigation in Uganda March 7, 2022 October 26, 2023
NCT05643781 Completed Tuberculosis as a Risk Factor for a Worse Outcome Post-Sars-CoV-2 Infection March 23, 2021 November 30, 2022
NCT05865626 Completed N/A Evaluation of the VOT Among Tuberculosis Patients From Lambaréné October 10, 2018 June 30, 2022
NCT06224608 Completed Phase 1 Phase I Clinical Trial to Evaluate the Safety of Recombinant Mycobacterium Tuberculosis Fusion Protein (EEC) in Healthy Adults Aged 18-65 and Patients With Pulmonary Tuberculosis January 17, 2023 May 9, 2023
NCT06239337 Completed Evaluation of Xpert MTB/RIF Ultra in Stools and Urine to Improve Tuberculosis Diagnosis in Children June 26, 2019 December 15, 2023
NCT06284187 Completed Diagnosis Test of Real-time Polymerase Chain Reaction (RT-PCR) for Pulmonary Tuberculosis January 1, 2023 December 31, 2023
NCT06396910 Completed TB and Sarcoidosis Granuloma September 1, 2021 July 1, 2023
NCT06457269 Completed N/A Evaluating the Potential of Large Language Models for Respiratory Disease Consultations October 1, 2023 April 4, 2024
NCT00731471 Completed Phase 1 A Phase I Study of a New Tuberculosis (TB) Vaccine, MVA85A, in Healthy Volunteers With HIV August 2008 January 2011
NCT00741169 Completed Phase 1 TMC435350-TiDP16-C105: Phase I, 3-way Crossover, Drug-drug Interaction Between TMC435350 and Rifampin After Multiple Dosing. June 2008 December 2008
NCT00749034 Completed Phase 1 Dose-Escalation Study on Safety and Immunogenicity of VPM1002 in Comparison With BCG in Healthy Male Volunteers September 2008 December 2009
NCT00756808 Completed Is Tuberculin Skin Testing Effective in Screening for Latent Tuberculosis (TB) in Elderly Residents of Nursing Homes? October 2007 July 2010
NCT00760149 Completed Phase 2 Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosis July 2010 September 2013
NCT00767975 Completed Phase 3 Active Screening of Latent TB Infection, Treatment and Long Term Follow-up in Prison January 2008 November 2010
NCT00771498 Completed Phase 4 An Evaluation of the Pharmacological Interaction of Lopinavir/r and Rifampin November 2008 December 2012
NCT00793702 Completed Phase 1 Safety and Risk of Sensitisation of the rdESAT-6 + rCFP-10 Skin Test Following Repeated Intradermal Administration November 2008 July 2009
NCT00797836 Completed Phase 4 Quantiferon for Detection of Latent Tuberculosis in Healthcare Workers November 2008 November 2010
NCT00801606 Completed Phase 3 Micronutrient Supplementation in in Paediatric Pulmonary Tuberculosis December 2008 June 2012
NCT00802802 Completed Phase 1 Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Children February 10, 2010 February 16, 2018
NCT00805272 Completed N/A Medical and Economical Impact of IGRAs Diagnosis of Latent Tuberculosis in HIV-infected Patients February 2009 February 2012
NCT00810407 Completed Safety And Efficacy Of Rifabutin In Patients For Non-HIV Patients November 2008 July 2016
NCT00810446 Completed Safety And Efficacy Of Rifabutin In HIV Patients June 2009 March 2018
NCT00811343 Completed N/A Impact of New Immunological Diagnosis Tests of Latent Tuberculosis Before Anti TNF Therapy December 2008 June 2012
NCT00814671 Completed Phase 2 Study of Daily Rifapentine for Pulmonary Tuberculosis April 2010 September 2014
NCT00816426 Completed Phase 1 Measurement of Anti-TB Drugs in Lung Tissue From Patients Having Surgery to Treat Tuberculosis December 29, 2008 December 29, 2017
NCT00822315 Completed Phase 2 Efficacy and Safety of 2 Raltegravir Doses in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis July 2009 May 2012
NCT00828529 Completed Phase 1 TMC207-TiDP13-C110: Interaction Study With Lopinavir/Ritonavir in Healthy Volunteer February 2009 May 2009
NCT00850915 Completed Phase 4 Feasibility and Effectiveness of Community Based Isoniazid Preventive Therapy in Kenya April 2009 November 2012
NCT00851630 Completed Phase 4 Tuberculosis and Human Immunodeficiency Virus (HIV) Immune Reconstitution Syndrome Trial (THIRST) June 2004 September 2007
NCT00857116 Completed N/A Deworming Against Tuberculosis March 2009 August 2013
NCT00857402 Completed N/A Arginine as an Adjuvant Treatment Against Tuberculosis February 2004 December 2006
NCT00865826 Completed Observational Study of Specificity of Mycobacterium Tuberculosis Screening and Diagnostics in HIV-Infected Individuals December 2009 March 2011
NCT00871949 Completed Phase 1 Safety, Tolerability And Pharmacokinetics Study Of Single Doses Of PNU-100480 In Healthy Adults April 2009 August 2009
NCT00889759 Completed The Role of High Resolution-Computed Tomography (CT) in Tuberculosis (TB) Outbreak Investigation December 2007 April 2009
NCT00910871 Completed Phase 2 To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB. September 2009 January 2013
NCT00915330 Completed N/A Rapid On-site Cytopathologic Evaluation in the Diagnosis of Hilar/Mediastinal Adenopathy May 2009 February 2010
NCT00918086 Completed Phase 2 Impact of Vitamin D Supplementation on Host Immunity to Mycobacterium Tuberculosis and Response to Treatment July 2009 July 2014
NCT00922363 Completed Phase 1 Trial on the Safety of a New Liposomal Adjuvant System, CAF01, When Given With the Tuberculosis Subunit Vaccine Ag85B-ESAT-6 as Two Injections With Two Months Interval to Healthy Adult Volunteers October 2009 October 2011
NCT00929396 Completed Phase 1 A Safety and Immunogenicity Trial With an Adjuvanted Tuberculosis (TB) Subunit Vaccine in Purified Protein Derivative (PPD) Positive Volunteers September 2007 June 2009
NCT00929786 Completed Anti-tuberculosis (TB) Drug Levels and Hepatotoxicity November 2007 June 2009
NCT00950612 Completed Phase 2 Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Healthy HIV Negative Adolescents December 8, 2009 September 30, 2010
NCT00953927 Completed Phase 2 A Study of MVA85A in Healthy Infants July 2009
NCT00962676 Completed Diagnostic Usefulness of Interferon Gamma Release Assay for Active Tuberculosis in Immunocompromised Patients July 2009 December 2010
NCT00962793 Completed Diagnosis of Latent Tuberculosis(TB) Infection in Health Care Workers Using TST and Whole Blood Interferon-γ Assay
NCT00972699 Completed Phase 2 Mentor Mothers: A Sustainable Family Intervention in South African Townships July 2008 December 2011
NCT00978510 Completed Study of Health Personnel and the Assistance to Patients With Tuberculosis in Hospital Environment January 2004 December 2006
NCT00979290 Completed Adverse Reactions and Efficacy of Fixed-dose Combination Anti-tuberculosis (TB) Drugs October 2008 November 2011
NCT00981071 Completed The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure May 2009 April 2010
NCT00982969 Completed The Clinical Utility of QuantiFERON in the Diagnosis of Active Tuberculosis June 2008 April 2010
NCT00990990 Completed Phase 1 Safety, Tolerability, Pharmacokinetics And Measurement Of Whole Blood Activity (WBA) Of PNU-100480 After Multiple Oral Doses In Healthy Adult Volunteers October 2009 May 2010
NCT00992069 Completed Phase 1 Safety, Tolerability, and Effect of TMC207 and Efavirenz in Healthy Volunteers December 2009 December 2010
NCT01003093 Completed Phase 1 A Safety and Immunogenicity Trial With an Adjuvanted Tuberculosis(TB) Subunit Vaccine November 2005 June 2008
NCT01017536 Completed Phase 2 Safety and Immunogenicity of AERAS-402 in HIV-infected, Bacillus Calmette-Guerin (BCG)-Vaccinated Adults December 2009 May 2012
NCT01021124 Completed Latent Tuberculosis Infection in Bone Marrow Transplant Recipients January 2010 June 2013
NCT01033929 Completed Phase 1 A Safety and Dose Finding Trial of C-Tb, When Given to Adult Patients Recently Diagnosed With Active Tuberculosis January 2010 November 2010
NCT01038830 Completed QuantiFERON Change During Anti-tuberculosis Medication May 2008 May 2010
NCT01048697 Completed Phase 4 Effect of Weight and/or Obesity on Ethambutol Drug Concentrations January 2010 December 2010
NCT01049282 Completed Phase 1 A Safety and Immunogenicity Trial With an Adjuvanted TB Subunit Vaccine (Ag85B-ESAT-6 + IC31) December 2008 April 2010
NCT01053598 Completed Evaluation Of The Performance Of The Nitrate Reductase And Resazurin Titre Assay For The Detection of Mycobacterium Tuberculosis Complex From Sputum In A High Tb and Hiv Setting September 2011 December 2012
NCT01061593 Completed Phase 3 Adjunct Immunotherapy With Immunoxel in Patients With TB and TB/HIV January 2010 April 2015
NCT01071603 Completed Tuberculosis in China February 2, 2010 January 29, 2018
NCT01098474 Completed Phase 2 Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Healthy Infants July 7, 2010 March 16, 2012
NCT01099098 Completed Prevalence of Latent Tuberculosis (TB) Infection Diagnosed by Interferon-gamma Release Assay and Tuberculin Skin Tests in Patients With Old Healed TB January 2010 March 2011
NCT01113281 Completed Phase 1 Dose-Escalation Study on Safety and Immunogenicity of VPM1002 in Comparison to BCG in Healthy Volunteers in South Africa April 2010 March 2011
NCT01119521 Completed Phase 1 Study of Pre-clearance of Latent Tuberculosis Infection And BCG Revaccination October 2010 July 2013
NCT01121068 Completed Monthly Follow up of Interferon Gamma Releasing Assay (IGRA) Among Health-care Workers Treating Tuberculosis (TB) Patients May 2010 December 2011
NCT01124929 Completed Phase 3 Treatment Duration for Abdominal Tuberculosis July 2008 April 2014
NCT01136161 Completed Phase 2 Clinical Trial to Investigate the Safety, Tolerability, and Immunogenicity of the Novel Antituberculous Vaccine RUTI® Following One Month of Isoniazid Treatment in Subjects With Latent Tuberculosis Infection June 2010 May 2011
NCT01137370 Completed The Impact of Vitamin D on Tuberculosis Among Koreans January 2010 April 2011
NCT01138202 Completed Phase 2 Pharmacokinetics (PK) and Safety of 2 Different Doses of Lopinavir/Ritonavir in in HIV/Tuberculosis (TB) Co-infected Patients Receiving Rifampicin Containing Anti-tuberculosis Therapy November 2010 December 2015
NCT01151189 Completed Phase 2 Efficacy Against TB Disease, Safety, and Immunogenicity of MVA85A/AERAS-485 in HIV-Infected Adults (C-030-485) July 2011 September 2014
NCT01162265 Completed Prognostic Value of Interferon Gamma Release Assays in Predicting Active Tuberculosis Among Individuals With, or at Risk of, Latent Tuberculosis Infection August 2010 June 30, 2016
NCT01162486 Completed Phase 1 Pharmacokinetics, Safety and Tolerability of Escalating Rifapentine Doses in Healthy Volunteers April 2010 March 2011
NCT01165840 Completed Phase 4 Effect of Weight and/or Obesity on Dapsone Drug Concentrations July 2010 May 2012
NCT01167452 Completed Phase 4 Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrations July 2010 May 2012
NCT01167647 Completed The Role of Routine Bacterial Culture Including Tuberculosis During Bronchoscopy: A Prospective Study July 2010 October 2012
NCT01181856 Completed Phase 1 Safety of Tuberculosis Vaccine, MVA85A, Administered by the Intramuscular Route and the Intradermal Route January 2010 January 2011
NCT01194180 Completed Phase 1 A BCG Challenge Model Study to Assess Anti-mycobacterial Immunity Induced by BCG and a Candidate TB Vaccine, MVA85A May 2010 January 2012
NCT01198366 Completed Phase 1/Phase 2 Study of AERAS-402 in Healthy Infants September 2010 April 2014
NCT01222338 Completed Phase 2 Safety and Efficacy of Oral Immunomodulator in Tuberculosis (TB) and TB/HIV Patients January 2010 January 2011
NCT01225640 Completed Phase 2 PNU-100480 In Newly Diagnosed, Drug Sensitive Patients With Pulmonary TB; Early Bactericidal Activity; Whole Blood Assay August 2011 December 2011
NCT01241188 Completed Phase 2 A Trial of the C-Tb Skin Test, When Given Intradermally to Adult Patients Recently Diagnosed With Active Tuberculosis (TB) April 2011 December 2011
NCT01242475 Completed Phase 2 A Trial of the C-Tb Skin Test, When Given Intradermally to Healthy Volunteers Previously Vaccinated With BCG April 2011 November 2011
NCT01244204 Completed N/A Role of Vitamin D in Innate Immunity to Tuberculosis November 2009 March 2011
NCT01245036 Completed N/A Efficacy of Antituberculous Therapy in Management of Sarcoidosis January 2009 March 2013
NCT01252537 Completed Immunosuppression in HIV-infected Patients With Tuberculosis in Ethiopia September 2010 January 2014
NCT01262976 Completed Phase 2 Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Human Immunodeficiency Virus (HIV)-Positive Adults January 17, 2011 June 4, 2015
NCT01288950 Completed N/A Vitamin D Supplementation Enhances Immune Response to Bacille-Calmette-Guerin (BCG) Vaccination in Infants February 2011 July 2012
NCT01290081 Completed N/A Enhanced Tuberculosis Case Detection Among Substitution Treatment Patients October 2007 January 2008
NCT01301144 Completed Oral Urea Breath Testing for Diagnosis and Treatment Response in Pulmonary Tuberculosis February 13, 2011 March 30, 2016
NCT01311505 Completed Phase 1 Bioequivalence Study Comparing Rifampicin In A Fixed-Dose Combination (Rifampicin+Isoniazid, Myrin© 2) And The Reference Drug (Rifampicin, Rimactane®) April 2011 May 2011
NCT01322841 Completed N/A Universal Screening for Tuberculosis and Anemia With the CHICA System October 2007 September 2010
NCT01331811 Completed N/A Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam)and Africa (Burkina Faso, Cameroon) April 2011 May 2014
NCT01340820 Completed Phase 1 Study of AERAS 422 in Healthy Adults December 2010 May 2012
NCT01341184 Completed Phase 1 TMC207 +/- Rifabutin/Rifampin October 21, 2011 May 23, 2012
NCT01356095 Completed N/A A Knowledge Translation Intervention for TB/HIV Treatment Adherence, in Zomba District, Malawi March 2011 May 2012
NCT01358162 Completed Phase 1 Phase IC Study of Safety and PK of SQ109 300mg Daily November 2010 April 2011
NCT01363765 Completed Phase 4 Xpert MTB/Rif, a New Tool for the Diagnosis of Pulmonary Tuberculosis in Two Municipalities in Brazil February 2012 October 2012
NCT01364324 Completed Pharmacokinetics of Anti-tuberculosis Drugs in Gastrectomized Patients September 2010 June 2020
NCT01376843 Completed Conversion Rate of (TST) Tuberculin Skin Test and Quantiferon-TB Gold In Tube Assay in Health Care Workers June 2011 May 2012
NCT01378312 Completed Phase 1 A Study to Evaluate Safety and Immunogenicity of AERAS-402 February 2011 March 2012
NCT01380119 Completed Phase 2 Tuberculosis (TB) Immunotherapy Phase 2 Study August 2011 August 2012
NCT01390987 Completed Access to Care and Adherence Tuberculosis (TB) Survey June 2011 December 2012
NCT01404312 Completed Phase 3 Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB) May 23, 2012 November 14, 2017
NCT01408914 Completed Phase 2 Trial of High-Dose Rifampin in Patients With TB September 2013 April 2016
NCT01422798 Completed An Open Cohort of Childhood Tuberculosis in Mbarara National Referral Hospital, Uganda April 2012 December 2014
NCT01424826 Completed Phase 1 The Effect of Intermittent Rifampicin on Raltegravir January 2012 July 2013
NCT01433796 Completed Screening for Tuberculosis in HIV-infected Patients Eligible for Antiretroviral Treatment October 2011 December 2015
NCT01450085 Completed N/A Chepetsa TB - Reducing TB Among HIV-Infected Malawians September 2012 December 30, 2016
NCT01456845 Completed Anti-tuberculosis (TB) Drug Levels and Correlation With Drug Induced Hepatotoxicity August 2010 June 2012
NCT01459120 Completed N/A Comparison of Door-to-door Versus Community Gathering to Provide HIV Counseling and Testing Services in Rural Lesotho October 2011 February 2012
NCT01471977 Completed N/A Treatment Adherence of Tuberculosis Medicines January 2004 February 2010
NCT01479972 Completed Phase 2 Study to Evaluate Safety and Immunogenicity of VPM1002 in Comparison With BCG in Newborn Infants in South Africa November 2011 November 2012
NCT01492595 Completed Screening of Children in Household Contact With Adult TB Patients in Mbarara Hospital, Uganda April 2012 April 2014
NCT01494038 Completed Phase 4 Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Women August 19, 2014 September 6, 2017
NCT01497769 Completed Phase 1 Safety of Tuberculosis Vaccine, MVA85A, Administered by the Aerosol Route and the Intradermal Route September 2011 April 2013
NCT01516203 Completed Phase 2 Phase 2a EBA Trial of AZD5847 December 5, 2012 December 24, 2013
NCT01517022 Completed Phase 3 Intensive Smoking-cessation Intervention Versus Smoking-cessation Advice in Smear-positive Patients With Pulmonary Tuberculosis November 2010 September 2016
NCT01530568 Completed N/A Gene Xpert Diagnosis of TB Using Tracheal Aspirates From Intensive Care Unit (ICU) Patients August 2010 July 2013
NCT01539005 Completed Tuberculosis Recurrence Upon Treatment With Highly Active Antiretroviral Therapy November 2009 April 23, 2014
NCT01545661 Completed N/A Utility of Sputum Induction and Novel Technologies to Improve TB Diagnosis in a High HIV Prevalence Primary Care Setting August 2009 May 2012
NCT01547884 Completed Effect of Filarial Infection on Immune Responses in Latent Tuberculosis January 1, 2013 August 7, 2020
NCT01554384 Completed N/A Trial of Point-of-treatment Xpert MTB/RIF Assay October 2010 July 2012
NCT01560078 Completed Efficacy Study of Thrice Weekly Directly Observed Treatment Short-Course Regimen in Tubercular Pleural Effusion September 2006 December 2012
NCT01571414 Completed Phase 1 Evaluating the Safety and Drug Interaction of PA-824, an Investigational Tuberculosis Medication, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampin May 2012 May 2013
NCT01574638 Completed Phase 1 Evaluating the Pharmacokinetics of High-Dose Rifapentine When Given as a Single Dose or in Divided Doses to Healthy Adults June 2012 June 2013
NCT01579214 Completed N/A Cell Phone Messaging to Improve Communication of Critical Laboratory Results to Patients in Rural Uganda July 2012 April 2015
NCT01585532 Completed Alere Mycobacterium Tuberculosis Urine Study January 2012 December 2013
NCT01585636 Completed Phase 1 Escalating Single-dose Safety, Tolerability, and Pharmacokinetics of SQ109 in Healthy Volunteers September 2006 February 2007
NCT01587469 Completed Evaluation of Xpert MTB/RIF Assay for the Rapid Identification of TB and TB Rifampin Resistance in Pulmonary Tuberculosis Suspects May 2012 February 21, 2014
NCT01587677 Completed Evaluation of a LAM FLISA for the Diagnosis of Tuberculosis February 2012 February 2013
NCT01589497 Completed Phase 2 Essentiality of INH in TB Therapy June 30, 2015 February 10, 2016
NCT01601275 Completed Database of All Patients With Microbiologically Proven Mycobacteria Tuberculosis Infection May 2012 May 2018
NCT01611402 Completed Gene Expression in HIV and Tuberculosis Co-infection May 29, 2012 April 6, 2016
NCT01616264 Completed Reproducibility of Computed Tomography January 2006 December 2009
NCT01622140 Completed Prospective Comparison of the Tuberculin Skin Test and Interferon-Gamma Release Assays in Diagnosing Infection With Mycobacterium Tuberculosis and in Predicting Progression to Tuberculosis October 2012 December 31, 2020
NCT01631266 Completed Phase 3 Comparison of Diagnostic Performance of C-Tb to QuantiFERON®-TB, in Combination With a Safety Assessment of C-Tb vs Tuberculin PPD RT23 SSI July 2012 October 2014
NCT01635153 Completed N/A Effects of a Protein Calorie Supplement in HIV-infected Women With Tuberculosis May 2012 July 2014
NCT01637558 Completed Phase 4 Optimal Dosing of 1st Line Antituberculosis and Antiretroviral Drugs in Children (a Pharmacokinetic Study) November 2012 July 31, 2017
NCT01642888 Completed Phase 3 A Trial in Subjects Suspected to Have Tuberculosis, Comparing the Diagnostic Performance of C-Tb to QuantiFERON®, in Combination With a Safety Assessment of C-Tb Versus Tuberculin PPD RT23 SSI September 2012 September 2014
NCT01650389 Completed Phase 2 Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination October 2012 May 2015
NCT01657656 Completed N/A Vitamin D Supplementations as Adjunct to Anti-Tuberculosis Drugs in Mongolia October 2012 July 2014
NCT01660646 Completed N/A Determining the Impact of Enhanced Case Finding on Tuberculosis Notification in The Gambia June 2012 October 2015
NCT01663701 Completed N/A Simplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia October 2012 January 2014
NCT01669096 Completed Phase 2 Study in Healthy Adults to Evaluate Gene Activation After Vaccination With GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine GSK 692342 August 21, 2012 May 24, 2013
NCT01674218 Completed Phase 1 Effect of PA-824 and of PA-824 Plus Moxifloxacin on the QTc Interval in Healthy Volunteers September 2012 December 2012
NCT01683773 Completed Phase 1 Safety Study of Tuberculosis Vaccines AERAS-402 and MVA85A September 2012 August 2014
NCT01690403 Completed Phase 1 Interaction Study to Assess the Pharmacokinetic Interaction of Oral Administration of Rifapentine on ATRIPLA™ in HIV Patients December 2012 March 2014
NCT01690754 Completed N/A Evaluating the Effectiveness of Interactive SMS Reminders on TB Treatment Outcomes March 2011 November 2014
NCT01705041 Completed N/A Preliminary Evaluation of a Point-Of-Care Liver Function Test June 2012 December 2012
NCT05571735 Enrolling by invitation Immunogenicity of COVID-19 Vaccines in Tuberculosis Patients April 15, 2023 December 14, 2024
NCT04151602 Enrolling by invitation Transmission of Tuberculosis Among Illicit Drug Use Linkages April 22, 2021 December 2024
NCT03228095 Enrolling by invitation Volatiles in Breath and Headspace Analysis - Diagnostic Markers July 24, 2017 December 31, 2025
NCT06338215 Not yet recruiting N/A Advice of Moderate Drinking Pattern Versus Advice on Abstention on Major Disease and Mortality May 1, 2024 June 30, 2029
NCT06253715 Not yet recruiting Phase 3 Shortened Regimen for Drug-susceptible TB in Children September 30, 2024 September 30, 2027
NCT06409572 Not yet recruiting Study of GeneXpert Mycobacterium Tuberculosis/ Rifampicin (MTB/RIF) Versus the Routine Methods for Detection of Mycobacterium Tuberculosis June 2024 July 2026
NCT04620772 Not yet recruiting Phase 2/Phase 3 Cyclophosphamide in the Treatment of Refractory Proliferative Arachnoiditis in CNS Tuberculosis January 1, 2021 December 31, 2024
NCT06019052 Not yet recruiting Evaluating Next Generation LAM Assays and Molecular Diagnostics (POC and Near POC) for the Diagnosis of TB Among People With Presumptive TB: a Prospective Multicentre Diagnostic Accuracy Study February 2024 November 2025
NCT06338462 Not yet recruiting N/A Cali Sin Tos Aim 2 May 2024 May 2025
NCT05917210 Not yet recruiting N/A Peer-led Implementation of TB-HIV Education and Adherence Counseling in Uganda September 2024 September 2026
NCT05845112 Not yet recruiting Start Taking Action For TB Diagnosis September 2023 October 2026
NCT05994144 Not yet recruiting N/A "Conducting A Study On Video Observed Therapy In The Management Of Tuberculosis" December 1, 2023 June 30, 2024
NCT06178666 Not yet recruiting N/A A Controlled Human Infection Model (CHIM) With Intradermal BCG in Malawi March 1, 2024 March 1, 2026
NCT06314386 Not yet recruiting N/A Systems Analysis and Improvement Approach to Prevent TB January 6, 2025 February 28, 2029
NCT05174741 Not yet recruiting N/A Pulmonary Rehabilitation in Non-chronic Obstructive Pulmonary Disease Patients. April 2023 February 2024
NCT05818059 Not yet recruiting N/A Active Close Contact Investigation of Tuberculosis Through Computer-aided Detection and Stool Xpert MTB/RIF Among People Living in Ethiopia May 2023 December 31, 2024
NCT06437184 Not yet recruiting N/A Increased Tuberculosis Case Detection - a Cluster-randomized Trial Combining Available Resources and Novel Strategies for High Endemic Areas June 3, 2024 March 31, 2026
NCT06017843 Not yet recruiting N/A Impact Evaluation of Use of MATCH AI Predictive Modelling for Identification of Hotspots for TB Active Case Finding September 2023 December 2024
NCT05805878 Not yet recruiting KAP Regarding Tuberculosis Among Physicians in Assiut City October 2023 October 2026
NCT05581212 Not yet recruiting N/A TB Case-Finding, Treatment and Prevention Intervention in Thailand May 1, 2024 July 31, 2026
NCT06401434 Not yet recruiting N/A Evaluation of CAD-based Triage for CXR Interpretation During TB Screening June 2024 December 2024
NCT05539989 Not yet recruiting Phase 1/Phase 2 Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa December 31, 2024 July 31, 2027
NCT06318416 Not yet recruiting Phase 1/Phase 2 Precision Rifampin Trial for Personalized Dosing July 1, 2024 January 30, 2028
NCT06221735 Not yet recruiting N/A Evaluating the Accuracy of New Tests for TB Infection Diagnosis April 2024 December 2025
NCT06058065 Not yet recruiting Sensitivity and Specificity of Xpert MTB/RIF Ultra December 11, 2023 December 25, 2024
NCT06113861 Not yet recruiting Diagnostic Innovations for Pediatric Tuberculosis in Bolivia May 2024 October 2028
NCT03896750 Not yet recruiting Phase 1 Single-Dose Study to Evaluate the PKs of Pretomanid in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function December 7, 2023 July 14, 2025
NCT06306430 Not yet recruiting Detection of Lipoarabinomannan in Urine Evaluation of the STANDARDTMF TBLAMFIA and Its Impact on the Initial TB Diagnosis May 2024 October 2025
NCT05110950 Not yet recruiting N/A Endobronchial Ultrasound Needle Aspiration With and Without Suction June 1, 2022 June 26, 2024
NCT05534750 Recruiting Phase 2 Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB) April 20, 2023 May 2025
NCT06199921 Recruiting Phase 2 ATORvastatin in Pulmonary TUBerculosis January 3, 2024 May 30, 2025
NCT05537038 Recruiting Phase 1 Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in Healthy Volunteers April 18, 2023 September 2025
NCT05542511 Recruiting Host Blood RNA Signatures for Diagnosis of TB June 23, 2022 September 2024
NCT05547464 Recruiting Phase 1/Phase 2 Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in BCG Vaccinated Volunteers July 31, 2023 February 2027
NCT05575518 Recruiting Phase 3 A Pragmatic Trial With Optimized Dose of Rifampicin and Moxifloxacin for the Treatment of Drug Susceptible Pulmonary Tuberculosis August 11, 2023 March 31, 2026
NCT03851159 Recruiting N/A Nyaditum Resae® as a Co-adjuvant During Treatment for Active Pulmonary Tuberculosis and Its Impact on the Gut Microbiota May 10, 2019 December 31, 2024
NCT04600167 Recruiting Phase 3 Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitus June 17, 2022 December 2025
NCT05220163 Recruiting N/A Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19 February 23, 2022 March 2025
NCT05236452 Recruiting N/A Effect of Integrating Traditional Tuberculosis Care With Modern Health Care on Case Detection July 1, 2022 December 30, 2023
NCT04738812 Recruiting Phase 3 Determination of Adequate Tuberculosis Regimen in Patients Hospitalized With HIV-associated Severe Immune Suppression April 21, 2022 March 2025
NCT06062238 Recruiting Phase 3 Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and Adults March 5, 2024 April 2028
NCT05259254 Recruiting N/A Effectiveness Of Mobile Application To Improve Adherence To Tuberculosis Treatment June 1, 2022 May 28, 2023
NCT05964842 Recruiting N/A Using SMS Reminders, Phone Calls and Money Incentives to Enhance Linkage to Care of Presumptive TB Patients in Uganda August 14, 2023 April 30, 2024
NCT05280886 Recruiting Multi-site Cohort Study for the Development of Personalized Pharmacotherapy in Patients With Tuberculosis (TB) July 24, 2018 February 28, 2025
NCT06305104 Recruiting Phase 2 Clinical Trial to Explore the Skin Test Dosage of EEC in People Aged 18 to 65 Years Old and the Safety and Preliminary Efficacy in People Aged 3 to 75 Years Old. July 18, 2023 June 30, 2024
NCT04746547 Recruiting Phase 4 Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB August 19, 2021 July 31, 2025
NCT05317247 Recruiting Cough Audio Classification as a TB Triage Test April 19, 2022 September 30, 2024
NCT05989802 Recruiting N/A Rapid Research in Diagnostics Development for TB Network (R2D2 Kids) and Assessing Diagnostics At POC for TB in Children (ADAPT for Kids) January 26, 2024 September 1, 2026
NCT05342064 Recruiting N/A Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered Service July 11, 2023 September 2025
NCT06141148 Recruiting Clinical Presentation, and Treatment Outcomes in Tuberculous Patients in Sohag Governorate November 1, 2023 December 30, 2024
NCT04472897 Recruiting Phase 1 A Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2556286 in Healthy Adult Participants October 30, 2020 July 4, 2024
NCT03625739 Recruiting Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis July 1, 2018 December 31, 2026
NCT05847491 Recruiting Latent Tuberculosis in Healthcare Workers - the Reality of a Portuguese Tertiary Hospital September 1, 2022 December 31, 2023
NCT05382312 Recruiting Phase 2 Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosis July 26, 2022 November 1, 2024
NCT03691883 Recruiting Design of an Integrative Algorithm for Staging Tuberculosis April 19, 2018 December 2024
NCT05406453 Recruiting N/A Whole Genome Sequencing of Tuberculosis for Disease Control in Madagascar May 16, 2022 September 1, 2025
NCT05423847 Recruiting Triage UltraSound in Tb Endemic Regions October 14, 2021 October 14, 2025
NCT01212003 Recruiting Training Protocol on the Natural History of Tuberculosis June 30, 2011
NCT05473520 Recruiting Phase 3 Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis May 24, 2023 January 27, 2027
NCT05526885 Recruiting N/A Tuberculosis Diagnostic Trial of CAD4TB Screening Alone Compared to CAD4TB Screening Combined With a CRP Triage Test, Both Followed by Confirmatory Xpert MTB/RIF Ultra in Communities of Lesotho and South Africa September 7, 2022 December 31, 2024
NCT06347939 Recruiting Mediastinal EBUS Cryobiopsy Study In Sweden April 1, 2024 December 31, 2028
NCT03800381 Recruiting Adequacy of the New Pediatric Isoniazid/Rifampin/Pyrazinamide (HRZ) Tablet January 28, 2019 August 31, 2024
NCT03800394 Recruiting Pharmacokinetics of Intracellular TFV-DP and FTC-TP in HIV-infected Adolescents January 28, 2019 August 31, 2024
NCT03800407 Recruiting Contributing Factors for Poor HIV Treatment Response in Children With TB/HIV Coinfection January 28, 2019 November 30, 2024
NCT04303104 Recruiting N/A Xpert Active Case-finding Trial 3 (XACT-3) March 26, 2021 December 1, 2024
NCT05756582 Recruiting Prevalence of Latent Tuberculosis Infection in Health-care Workers and Students November 17, 2021 December 15, 2026
NCT04052022 Recruiting Paradoxical Tuberculosis Reactions in Patients Without HIV Infection December 20, 2019 April 30, 2029
NCT06022146 Recruiting Phase 3 TB YOUTH - TB sYstemic Management Using One-month, Ultra-short TPT Regimen for scHool Contacts September 1, 2023 September 1, 2026
NCT06033807 Recruiting Active Screening of Latent Tuberculosis Infection in School Contacts of Active Tuberculosis Patients September 1, 2023 December 31, 2025
NCT05820594 Recruiting N/A Using BCG Vaccine to Understand Tuberculosis Infection June 30, 2023 March 1, 2024
NCT05824091 Recruiting Phase 1 Safety, Tolerability, Pharmacokinetics (PK), and Food Effect of MK-7762 in Healthy Adults February 23, 2023 October 16, 2024
NCT05840809 Recruiting Pharmacokinetics of Drugs Used to Treat Drug Sensitive Tuberculosis in Breastfeeding Mother-infant Pairs January 20, 2022 January 29, 2024
NCT05842161 Recruiting N/A South Africa Smoking Cessation and Engagement in HIV/TB Care Care March 12, 2024 March 31, 2026
NCT04930744 Recruiting Phase 2 Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) August 26, 2021 November 1, 2025
NCT06403943 Recruiting Phase 4 Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis May 29, 2023 December 31, 2026
NCT05175794 Recruiting Triage Test for All Oral DR-TB Regimen (TRiAD Study) May 26, 2022 June 1, 2025
NCT04975178 Recruiting Phase 3 Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa September 23, 2022 September 2029
NCT04975737 Recruiting Phase 3 Study of the Safety and Efficacy of the Subunit Recombinant Tuberculosis Vaccine GamTBvac January 20, 2022 November 2025
NCT06047795 Recruiting N/A Endurance Training in Patients With Post-TB Lung Disease September 11, 2023 July 2024
NCT04985994 Recruiting Potential Role of Microbiome in Tuberculosis August 22, 2021 August 31, 2024
NCT05007821 Recruiting Phase 2 Linezolid Dosing Strategies in Drug-Resistant TB August 11, 2022 November 14, 2025
NCT05042063 Recruiting Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease September 15, 2021 September 15, 2026
NCT04518228 Recruiting Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum September 1, 2021 March 11, 2026
NCT04618198 Recruiting Phase 3 Early Empiric Anti-Mycobacterium Tuberculosis Therapy for Sepsis in Sub-Saharan Africa December 10, 2021 June 25, 2025
NCT05047315 Recruiting Evaluating a New Stool Based qPCR for Diagnosis of Tuberculosis in Children and People Living With HIV December 1, 2021 September 30, 2025
NCT05868005 Recruiting N/A Delivering a Multi-disease Screening Tool to Migrant Populations October 23, 2023 September 2024
NCT06054334 Recruiting Relevance of Isoniazid Dosage in Adults Treated for Tuberculosis January 4, 2023 October 2024
NCT05091580 Recruiting N/A Effectiveness and Cost-Effectiveness of Depression Treatment for Individuals With TB in South Africa March 23, 2023 September 30, 2026
NCT03141060 Recruiting Phase 1/Phase 2 Evaluating the Pharmacokinetics, Safety, and Tolerability of Delamanid in Combination With Optimized Multidrug Background Regimen (OBR) for Multidrug-Resistant Tuberculosis (MDR-TB) in HIV-Infected and HIV-Uninfected Children With MDR-TB January 30, 2018 July 20, 2026
NCT04538911 Recruiting Phase 1 Phase I Clinical Protocol for Pre-evaluation of the Safety of BCG-PPD in Tuberculosis Patients July 2, 2021 August 2023
NCT05118490 Recruiting Phase 4 Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients July 19, 2023 December 31, 2024
NCT05122767 Recruiting Phase 1/Phase 2 Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS) May 24, 2023 December 2025
NCT05941052 Recruiting N/A Assessing Diagnostics At Point-of-care for Tuberculosis August 28, 2023 September 30, 2028
NCT06246851 Recruiting N/A BCG Revaccination Study in Diabetic and Non-Diabetic Adults February 2024 November 2027
NCT06403800 Recruiting Silicosis and Silicotuberculosis Among Small Scale Gemstone Miners in Northern Tanzania March 11, 2024 December 1, 2025
NCT05947890 Recruiting Phase 2 Evaluating the Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living With and Without HIV in South Africa January 30, 2024 November 30, 2024
NCT05586230 Recruiting Phase 1 Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis October 3, 2023 January 31, 2026
NCT06354257 Recruiting Phase 1 A Study to Investigate the Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With GSK3036656 in Female Participants of Non-childbearing Potential Aged 18 to 65 Years of Age April 5, 2024 October 30, 2024
NCT06214910 Recruiting Phase 4 ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa February 20, 2024 December 31, 2026
NCT05609552 Recruiting Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PET May 22, 2023 February 1, 2026
NCT06221488 Recruiting Testing Health Workers At Risk to Advance Our Understanding of TB Infection January 15, 2024 December 31, 2029
NCT05610098 Recruiting Gene Expression Profiles in Spinal Tuberculosis. October 25, 2022 December 2025
NCT05628454 Recruiting N/A Comparison of Three Different Puncture Techniques in EBUS-TBNA November 1, 2022 November 1, 2024
NCT04568967 Recruiting N/A TB-CAPT EXULTANT - HIV September 5, 2022 December 30, 2024
NCT05916638 Recruiting MoMa Signature During Granulomatosis January 15, 2024 October 2025
NCT02454569 Recruiting Vicente Ferrer HIV Cohort Study September 2009 January 2040
NCT05655702 Recruiting N/A DRug Use & Infections in ViEtnam: TuBerculosis Control October 2, 2023 June 2025
NCT04923958 Recruiting N/A Rapid Research in Diagnostics Development for TB Network April 14, 2021 May 31, 2025
NCT05656287 Recruiting N/A My Mobile Wallet: An Intervention for Tuberculosis Medication Adherence in Rural Uganda April 14, 2022 May 2026
NCT05686356 Recruiting Phase 2/Phase 3 A Pan-TB Regimen Targeting Host and Microbe July 28, 2023 September 30, 2025
NCT05738681 Recruiting Phase 2/Phase 3 Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trial September 9, 2022 May 31, 2023
NCT05739695 Recruiting N/A A Trial of Radial EBUS Versus VBN for the Peripheral Pulmonary Lesions February 1, 2022 March 1, 2025
NCT04230395 Recruiting N/A Alcohol Reduction Among People With TB and HIV in India September 22, 2022 August 31, 2026
NCT04033718 Recruiting N/A Inpatient Package to Reduce HIV and AIDS-related Death in Zambia October 1, 2021 June 30, 2024
NCT02387242 Suspended Phase 1 Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Rifampicin in Healthy Volunteers February 2015 December 2017
NCT05284812 Suspended Phase 2 A Phase Ⅱ Clinical Trial of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02) February 10, 2022 December 31, 2024
NCT01350674 Suspended N/A Role of EBUS-TBNA in Diagnosing TB in Mediastinal/Hilar Lymph Nodes December 2010 March 2018
NCT05330884 Suspended Phase 3 BCG Revaccination in Children and Adolescents July 15, 2024 December 2027
NCT00440544 Terminated Phase 1 A Phase I Trial of a LTK63 Adjuvated Tuberculosis Nasal Subunit Vaccine (Ag85B-ESAT6) January 2007 February 2008
NCT01417988 Terminated Phase 4 Prevention of Early Mortality by Presumptive Tuberculosis (TB) Treatment August 2011 June 2013
NCT03302949 Terminated N/A Treating Tuberculosis Wasting With a High-protein Supplement August 1, 2017 January 30, 2023
NCT00397709 Terminated Phase 4 Short-Course Isoniazid and Rifampin Compared With Isoniazid for Latent Tuberculosis Infection March 1996 February 2006
NCT01424501 Terminated Phase 2 Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Adults With TB Disease November 14, 2011 April 10, 2014
NCT00341042 Terminated Collection of Tissue Specimens in Mali, West Africa, for HIV and Tuberculosis Research January 4, 2005 May 1, 2013
NCT00523458 Terminated Phase 4 A Study to Determine the Best Dose of Antivirals in Patients With Both TB and HIV July 2007 March 2008
NCT01014481 Terminated Phase 4 Appropriate Timing of HAART in Co-infected HIV/TB Patients October 2009 May 2011
NCT02422524 Terminated Phase 1 Pretomanid in Adults With Hepatic Impairment December 11, 2017 November 17, 2023
NCT01131351 Terminated Phase 2 Safety and Pharmacokinetics (PK) in Multidrug-Resistant (MDR) Refractive Tuberculosis February 19, 2010 May 12, 2011
NCT04285905 Terminated Phase 2/Phase 3 Male Partner-assisted Contact Tracing for HIV and Tuberculosis in Malawi April 10, 2019 March 28, 2020
NCT00737724 Terminated N/A Simultaneous Versus Sequential Antiretroviral Therapy (ARV) Therapy and Mycobacterium Tuberculosis (MTB) Treatment March 2008 February 2011
NCT00145184 Terminated Phase 3 Effect of Multivitamin Supplements on Clinical and Immunological Response in Childhood Tuberculosis May 2005 August 2007
NCT03334734 Terminated Phase 2 Phase 2a Study of PBTZ169 December 16, 2016 February 22, 2018
NCT00533390 Terminated Phase 4 Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mg January 2007 October 2012
NCT00728507 Terminated Phase 2 Rifapentine Plus Moxifloxacin for Treatment of Pulmonary Tuberculosis November 2009 April 2013
NCT02606214 Terminated Phase 1 A Multiple Ascending Dose Study With a Dose Formulation Comparison Cohort to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult Subjects November 2015 December 2016
NCT00568854 Terminated N/A Immunobiology of Diabetes and Tuberculosis April 2007 March 2008
NCT00800670 Terminated Phase 1 Study of the Safety and Immunogenicity of an Adenovirus-based Tuberculosis Vaccine June 2009 July 2013
NCT01601626 Terminated Phase 2 Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV July 13, 2013 June 28, 2017
NCT00743470 Terminated Phase 1 A Bioavailability Study of Rifabutin and Lopinavir/Ritonavir in Healthy Adult Subjects August 2008
NCT01700790 Terminated Phase 4 Pharmacokinetic Study of Super-boosted Lopinavir/Ritonavir Given With Rifampin February 2016 December 31, 2018
NCT01895582 Terminated Performance of IGRAs for TB Infection Diagnosis in Elderly July 17, 2013 March 17, 2019
NCT00080119 Terminated Phase 2/Phase 3 Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIV February 2004 May 2009
NCT02532036 Terminated Phase 1 MVA85A Aerosol vs Intramuscular Vaccination in Adults With Latent Mycobacterium Tuberculosis (M. tb) Infection September 2015 October 4, 2018
NCT03084614 Terminated CD8 Reactivity to Microorganisms in Blood and Breast Milk March 28, 2017 November 8, 2019
NCT01329250 Terminated Phase 4 Pharmacokinetics and Safety of Moxifloxacin May 2011 August 2016
NCT04242472 Unknown status N/A SMS-based Mobile Health Intervention for Nutritional Status and Treatment Outcome Among TB Patients July 2020 March 2021
NCT00728546 Unknown status Phase 4 NAT2 in Re-challenge of INH in Patients With Hepatitis June 2008 November 2015
NCT04242511 Unknown status Tuberculosis Drug Levels in Diabetics May 2021 May 2022
NCT04249531 Unknown status Phase 1 Pharmacokinetic Evaluation and Local Tolerability of Dry Powder Amikacin Via the Cyclops™ June 1, 2020 June 1, 2022
NCT00332306 Unknown status Phase 3 Safety and Efficacy of Two Once Daily Anti Retroviral Treatment Regimens Along With Anti-tuberculosis Treatment June 2006 December 2011
NCT04271397 Unknown status N/A Immunological Biomarkers in Tuberculosis Management September 30, 2019 April 9, 2023
NCT00780546 Unknown status Spatial Epidemiology of Tuberculosis (TB) Infection October 2008 July 2009
NCT00313066 Unknown status Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion November 2005 November 2006
NCT04443283 Unknown status The Effect of Latent Tuberculosis Infection on the Pregnancy Outcome of IVF-ET January 1, 2019 December 30, 2022
NCT00311220 Unknown status Phase 4 Use TST and QFT-RD1 Test to Monitor the Tuberculous Infection in Patients, Close Contact People and Health Care Workers January 2004 November 2006
NCT04490746 Unknown status Identifcation of Biomarkers for Active Pulmonary Tuberculosis October 1, 2020 October 1, 2022
NCT04513379 Unknown status Phase 3 Efficacy of 400 mg Efavirenz Versus Standard 600 mg Dose in HIV/TB Co-infected Patients November 1, 2020 January 31, 2023
NCT02497079 Unknown status N/A Diagnostic Accuracy of Polymerase Chain Reaction for Mycobacterium Tuberculosis Using EBUS-TBNA Samples July 2015 December 2018
NCT00311207 Unknown status Development of Tuberculosis Diagnostic Kit December 2005 November 2006
NCT00904956 Unknown status Study of Latent Tuberculosis Infection (LTBI) by High Resolution Scanner November 2009 December 2012
NCT02508610 Unknown status DNA Sequencing of MDR TB in Eastern Siberia November 2013 November 2018
NCT04545788 Unknown status N/A Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant Tuberculosis August 1, 2020 December 31, 2022
NCT04547738 Unknown status Influence of Filarial Infections on Tuberculosis Disease and Tuberculosis Vaccination in Cameroon December 1, 2020 October 1, 2023
NCT00925249 Unknown status Comparison of the Tuberculin Skin Test (TST) and QuantiFERON ®-TB Gold Test (QFT-G) In Patients With Rheumatoid Arthritis Being Considered for Anti-TNF-Alpha Therapy May 2009 June 2011
NCT00309673 Unknown status N/A Local Anesthesia and Tuberculin Skin Test in Infants and Children
NCT00932854 Unknown status N/A A Clinical tRial of Endobronchial Ultrasound for the Diagnosis of MEDiastinal lymphadenopathY (REMEDY) July 2009 October 2011
NCT00285441 Unknown status Identification of Cytokine Profiles and T Cell Subsets Among Immunosuppressed Patients at Risk of Developing Active Tuberculosis November 2005 September 2008
NCT02563327 Unknown status Phase 3 Pharmacokinetic and Pharmacodynamic Study of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosis May 30, 2016 March 2020
NCT02573623 Unknown status Evaluation of an Innovative Tuberculosis Diagnostic Test July 2013 December 2015
NCT04567498 Unknown status N/A eNose-TB: Electronic Nose for Tuberculosis Screening December 2, 2021 December 31, 2022
NCT00242047 Unknown status Phase 4 Randomized Controlled Trial of Percutaneous and Intradermal BCG Vaccination. March 2001 August 2006
NCT04583904 Unknown status Prospective Evaluation of Novel Diagnostics for Tuberculosis in KwaZulu-Natal, South Africa September 18, 2019 September 2021
NCT02627209 Unknown status N/A The Serum Angiotensin Converting Enzyme and Lysozyme Levels in Patients Non-infectious and Infectious Uveitis June 2014 January 2017
NCT04600232 Unknown status N/A TB-LAM in the Diagnosis of TB October 2020 February 2021
NCT01040611 Unknown status N/A Effectiveness of Music Therapy October 2009 September 2010
NCT01059422 Unknown status Phase 4 Raltegravir + Lamivudine/Abacavir in HIV/Tuberculosis Co-Infected Patients October 2010
NCT04677478 Unknown status Impact of the Respiratory Isolation on the Quality of Life in Patients Hospitalized for Tuberculosis or COVID-19 December 2020 January 2022
NCT00216385 Unknown status Phase 3 A Controlled Trial of a 4-Month Quinolone-Containing Regimen for the Treatment of Pulmonary Tuberculosis January 2005 December 2008
NCT04709159 Unknown status N/A Impact of Mobile Health Interactive Software on Tuberculosis Outcomes; The Call for Life (CFLU-TB) Project October 19, 2020 July 2022
NCT04721080 Unknown status Pulmonary Tuberculosis Sequelae in Patients With COPD May 1, 2020 May 1, 2021
NCT04734236 Unknown status N/A Development of Molecular Diagnostic Platform for Tuberculosis January 28, 2021 December 31, 2021
NCT00620438 Unknown status Phase 4 Drug Interaction Between Coartem® and Nevirapine, Efavirenz or Rifampicin in HIV Positive Ugandan Patients February 2008 July 2011
NCT02735590 Unknown status Phase 2/Phase 3 The Correlate of Risk Targeted Intervention Study September 20, 2016 December 31, 2019
NCT04768231 Unknown status Phase 2 Rifampicin at High Dose for Difficult-to-Treat Tuberculosis April 1, 2021 December 31, 2023
NCT02744521 Unknown status N/A Training Inmate Peer Educators in Detecting Tuberculosis in a Developing Country Prison: A Cluster Randomized Trial March 2016
NCT04777721 Unknown status Phase 1 Aerosol BCG Challenge Study in Historically BCG-vaccinated Volunteers May 17, 2022 September 2023
NCT00216333 Unknown status Phase 4 Multicenter Trial for the Evaluation of a Fixed Dose Combined Tablet for the Treatment of Pulmonary Tuberculosis December 2003 June 2007
NCT00214708 Unknown status Can Screening People Registering With Primary Care Improve the Detection of Tuberculosis? January 2002 September 2004
NCT01182259 Unknown status The Incidence and Risk Factors of Side Effects During the Initial Phase of Rifater Therapy - a Prospective Study October 2009
NCT02807025 Unknown status Nasal, Tracheal and Bronchial Mucosal Lining Fluid(MLF) Sampling From Patients With Respiratory Diseases September 2015 December 31, 2017
NCT00018083 Unknown status N/A Intensive Pharmacokinetics of the Nelfinavir-Rifabutin Interaction in Patients With HIV-Related Tuberculosis Treated With a Rifabutin-Based Regimen
NCT01223976 Unknown status Phase 4 Sensitivity and Specificity of QuantiFeron -TB Gold Test (QFT-G)in Patients With Psoriasis November 2010 August 2011
NCT02845570 Unknown status Phase 1 Evaluation of Somatostatin Receptor Imaging Using PET/MRI as a Novel Approach to Detecting Pathology in Pulmonary TB July 2016
NCT00608790 Unknown status N/A Rapid Diagnosis of Pulmonary Tuberculosis February 2008 April 2013
NCT02913365 Unknown status Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis October 2012 June 2017
NCT00203762 Unknown status N/A Effect of Public Sector Antiretroviral Treatment Programme on Tuberculosis and Immunization Care May 2003 December 2006
NCT01315301 Unknown status N/A Optimal Time to Initiate Antiretroviral Therapy in HIV & TB Coinfected Adults Being Treated for Tuberculosis August 2008 March 2012
NCT01322685 Unknown status Development and Application of Rapid Nucleic Acid Diagnostic Kits for Clinical Specimens July 2010 June 2011
NCT02959684 Unknown status Strategic Screening for Infectious Diseases (Tuberculosis, HIV, HBV, HCV) Amongst Migrants in France April 14, 2017 July 2019
NCT02968927 Unknown status Phase 2 TB Host Directed Therapy November 2016 December 2020
NCT00174083 Unknown status Diagnosis of Active Tuberculosis by ELISPOT August 2005 December 2006
NCT04972903 Unknown status Impact of Malnutrition on Pharmacokinetic or Rifampicin, Isoniazid, Pyrazinamide and Ethambutol in TB-HIV Co-infected Children August 2021 December 2022
NCT01365702 Unknown status Tiotropium in Patients With Tuberculosis (TB) Destroyed Lung June 2011 December 2012
NCT03044509 Unknown status Diagnosis of Tuberculosis in Swiss Children May 12, 2017 December 2022
NCT00173264 Unknown status Immunologic and Genetic Characteristics of Monoclonal Immunoglobulins in Patient With Tuberculosis June 2005 June 2005
NCT00551226 Unknown status Follow up of Autoantibodies in Active Tuberculosis November 2007 November 2008
NCT01436929 Unknown status N/A Effect of Prophylactic Use of Silymarin on Hepatotoxicity Induced by Anti-tuberculosis Drugs September 2011 December 2013
NCT05077813 Unknown status Phase 2 Utilizing the Crosstalk Among Chicoric Acid, 13-Cis Retinoic Acid(Aerosolized), Minocycline and Vitamin D as a Potent Quadrate Therapy for Treating Patients With Multidrug-resistant TB and Patient With Both Multidrug-resistant TB and COVID-19 December 2021 February 2022
NCT00692809 Unknown status Impact of HIV Infection on Latent Tuberculosis (TB) Among Patients With HIV-TB Co-infection July 2008 March 2010
NCT03159364 Unknown status Phase 1/Phase 2 Antigen-specific Cytotoxic T Cells in the Treatment of Opportunistic Infections July 15, 2017 December 31, 2021
NCT05116098 Unknown status Phase 1 Randomized Clinical Trial: IS Zinc and Zinc Ionophere EGCG as Supplement Improve Outcome of Active Pulmonary Tuberculosis November 30, 2021 November 30, 2022
NCT01525134 Unknown status N/A Feasibility of a Lateral Flow Urine Lipoarabinomannan (LAM) Test for Diagnosis of Tuberculosis January 2011 April 2012
NCT03199690 Unknown status Phase 1 A Clinical Study Investigating Rifampicin and Dolutegravir in Combination in Healthy Volunteers October 2017 March 2018
NCT05124678 Unknown status Phase 2 Pharmacogenetics-guided Isoniazid Dosing in TB-HIV December 7, 2021 June 30, 2022
NCT05139940 Unknown status Validation of Artificial Intelligence Enabled TB Screening and Diagnosis in Zambia November 22, 2021 November 30, 2022
NCT03341195 Unknown status N/A Mobile Phone SMS Messages and Automated Calls in Improving Vaccine Coverage Among Children in Pakistan January 2018 September 2018
NCT05249699 Unknown status N/A The Prophylaxis of Tuberculosis According to TSPOT Results After Kidney Transplantation April 1, 2022 August 1, 2023
NCT03363178 Unknown status Phase 1 Study to Investigate the Safety and Efficacy of GC3107 (BCG Vaccine) in Healthy Adults December 14, 2017 March 31, 2018
NCT03423550 Unknown status Development of a Rapid and Accurate Diagnostic Assay for Tuberculosis January 16, 2018 December 30, 2021
NCT03459768 Unknown status Cohort Study on People Who Inject Drugs in Senegal August 24, 2016 June 30, 2021
NCT03507816 Unknown status A Multidrug-resistant (MDR) and Extensively Drug- Resistant (XDR) Tuberculosis Study in Alsace February 23, 2018 February 2020
NCT01663168 Unknown status Phase 2 EARNEST Rifabutin Pharmacokinetics (PK) Substudy December 2011 January 2014
NCT03519425 Unknown status N/A A Pragmatic Randomised Study to Optimise Screening, Prevention and Care for Tuberculosis in Malawi November 15, 2018 June 2020
NCT00172783 Unknown status PPD Size and Mycobacteria Tuberculosis ELISPOT in Children Who Have Received BCG in Neonate Period June 2005 December 2005
NCT01685905 Unknown status The Usefulness of Interferon-γ Release Assays and Tuberculin Skin Test for Detection of Latent Tuberculosis Infection April 2012 September 2013
NCT01687504 Unknown status Pharmacokinetics of Anti-TB Drugs in HIV/TB Co-infected Children in Ghana October 2012 May 2017
NCT01693224 Unknown status N/A Feasibility of a Lateral Flow Urine LAM Test for Diagnosis of Tuberculosis in South Africa April 2011 February 2013
NCT01699633 Unknown status Rifampin and Nevirapine Interactions in Young Children October 2012 May 2017
NCT01704144 Unknown status Rifampin and Efavirenz Interactions in Older Children October 2012 May 2017
NCT05376189 Unknown status Phase 2/Phase 3 Oral Vitamin D and Toll Like Receptor in Spondylitis Tuberculosis July 1, 2022 February 1, 2023
NCT01724723 Unknown status Phase 4 Using Entecavir to Reduce Hepatitis in Highly Viremic HBV Patients During Anti-tuberculous Treatment December 2012 June 2014
NCT03739736 Unknown status TB Reduction Through ART and TB Screening Project June 12, 2018 April 30, 2021
NCT01836822 Unknown status N/A Bronchoscopic Sampling Techniques in Sarcoidosis March 2013 May 2014
NCT03800888 Unknown status N/A Real-time Tuberculosis Medication Adherence Intervention in Rural Southwestern Uganda January 10, 2019 July 2021
NCT03806686 Unknown status Phase 2 Phase 2a Clinical Trial of ID93+GLA-SE Vaccine in BCG-vaccinated Healthy Healthcare Workers May 31, 2018 June 2020
NCT03806699 Unknown status Phase 1 Phase 1 Clinical Trial of ID93+GLA-SE Vaccine in BCG-vaccinated Healthy Adolescent April 2, 2019 December 2020
NCT01986543 Unknown status Phase 2 Interaction Between High Dose Rifampicine and Efavirenz in Pulmonary Tuberculosis and HIV Co-infection December 2013 December 2017
NCT01992263 Unknown status N/A Vitamin D Supplementation and TB June 2021 February 2023
NCT00512330 Unknown status Lipoarabinomannan (LAM) Enzyme-Linked Immunosorbent Assay (ELISA) in Diagnostics of Childhood Tuberculosis (TB) August 2007 August 2008
NCT00507000 Unknown status Phase 3 Pulmonary Tuberculosis and Vitamin D May 2008 September 2012
NCT02060006 Unknown status Phase 3 TB-IRIS NSAID Cox-2 Inhibitor Prevention Trial April 2014 April 2015
NCT00491933 Unknown status N/A Quantiferon-TB Gold in the Assessment of Latent TB in Patients Candidate to Treatment or Treated With TNFα Antagonists June 2007 October 2007
NCT00004740 Unknown status N/A Randomized Study of Interventions to Enhance Adherence to Isoniazid Prevention Therapy for Tuberculosis in Injection Drug Users February 1995
NCT00474435 Unknown status Phase 2 Pharmacokinetics of Emtricitabine/Tenofovir/Efavirenz in HIV-infected Patients With Tuberculosis November 2008 December 2009
NCT04002869 Unknown status Innovation in Tuberculosis January 1, 2019 December 31, 2022
NCT04015713 Unknown status Lowering InterLeukin-1 Receptor Antagonist Concentrations After TB Treatment Onset January 21, 2020 March 2021
NCT00456469 Unknown status Diagnosis of Active and Latent TB Infection With IFN-y Assays in African Children May 2007 October 2009
NCT02174380 Unknown status N/A Effectiveness of Active Case Finding of Household Contacts in a Routine Tuberculosis (TB) Control Program October 2012 June 2015
NCT04121026 Unknown status N/A Validation of a Tuberculosis Treatment Decision Algorithm in HIV-infected Children October 2, 2019 June 30, 2022
NCT02245347 Unknown status Genome Sequencing of Multidrug Resistant Tuberculosis (MDR TB) in Sputum April 2013
NCT00376012 Unknown status Phase 3 Short Course Intermittent Regimens for the Treatment of HIV-Associated Tuberculosis February 2001 September 2008
NCT02331732 Unknown status N/A Virtually Observed Treatment (VOT) for Tuberculosis Patients in Moldova October 2015 March 2017
NCT04232618 Unknown status Point-of-care Triage Test for Active Tuberculosis November 5, 2020 March 2024
NCT04240990 Unknown status N/A Development of a Diagnostic Prediction Score for Tuberculosis in Hospitalized Children With Severe Acute Malnutrition November 4, 2019 November 4, 2020
NCT02355223 Unknown status N/A Finding and Treating Unsuspected and Resistant TB to Reduce Hospital Transmission August 2016 February 2020
NCT05136833 Withdrawn Phase 2 Evaluation of Efficacy and Safety of the Concomitant of RUTI® Immunotherapy With the Standard Treatment in TB Patients December 1, 2021 December 31, 2022
NCT01442428 Withdrawn Phase 2/Phase 3 Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) Treatment Trial January 2014 June 2016
NCT02911740 Withdrawn N/A Additive Benefit of the Urine LAM Test to Current TB Diagnostics in HIV Positive Adults in Panama City, Panama November 2017 August 2018
NCT00212498 Withdrawn Tuberculosis Research Blood Bank November 2006
NCT02605538 Withdrawn N/A Hepatitis B in Cystic Fibrosis and Latent Tuberculosis Respectively September 1, 2015 December 31, 2025
NCT02021747 Withdrawn Biologic Basis Of Increased Susceptibility Of Smokers To Pulmonary Infection With Mycobacterium Tuberculosis January 2014 October 2016
NCT04551573 Withdrawn Phase 4 A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects May 2021 November 2021
NCT00414414 Withdrawn Phase 3 A RCT of Prednisone as Adjunctive Therapy for Hospitalized Patients With Pulmonary TB and HIV Co-infection February 2007 June 2009
NCT01874314 Withdrawn Phase 1 Effects of SQ109 on QTc Interval in Healthy Subjects December 2015
NCT03639038 Withdrawn Tuberculosis Diagnosis by Flow Cytometry September 30, 2018 July 1, 2019
NCT00788320 Withdrawn N/A Vitamin D in Active Tuberculosis (TB) Study October 2008 February 2010
Disase is a (Disease Ontology)
DOID:0050338
Cross Reference ID (Disease Ontology)
GARD:7827
Cross Reference ID (Disease Ontology)
MESH:D014375
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:15202009
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0041295
OrphaNumber from OrphaNet (Orphanet)
3389
ICD10 preferred id (Insert disease from ICD10)
D0000071
ICD10 class code (Insert disease from ICD10)
MeSH unique ID (MeSH (Medical Subject Headings))
D014376