pancreatic adenocarcinoma (Cancer)

Search with Google Search with Bing
Information
Disease name
pancreatic adenocarcinoma
Disease ID
DOID:4074
Description
"A pancreatic carcinoma that derives_from epithelial cells of glandular origin." [url:http\://en.wikipedia.org/wiki/Adenocarcinoma]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03983954 Active, not recruiting Phase 1 Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumors October 10, 2019 October 1, 2026
NCT04837118 Active, not recruiting N/A Resistance Training Intervention to Improve Physical Function in Patients With Pancreatic Cancer Receiving Combination Chemotherapy or Have Undergone Surgery, PancStrength Study February 15, 2021 December 31, 2026
NCT01013649 Active, not recruiting Phase 3 Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery April 5, 2010 February 13, 2025
NCT05973331 Active, not recruiting Prospective Validation of an EHR-based Pancreatic Cancer Risk Model July 17, 2023 September 2026
NCT05451849 Active, not recruiting Phase 1/Phase 2 A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer June 21, 2022 October 30, 2028
NCT03033927 Active, not recruiting Predicting Effective Therapy in Pancreatic Cancer January 24, 2017 January 24, 2025
NCT03816358 Active, not recruiting Phase 1 Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer December 9, 2019 January 31, 2025
NCT02879318 Active, not recruiting Phase 2 Gemcitabine and Nab-Paclitaxel vs Gemcitabine, Nab-Paclitaxel, Durvalumab and Tremelimumab as 1st Line Therapy in Metastatic Pancreatic Adenocarcinoma November 7, 2016 December 31, 2024
NCT03193190 Active, not recruiting Phase 1/Phase 2 A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer) July 5, 2017 October 31, 2026
NCT03138720 Active, not recruiting Phase 2 Pre-operative Treatment for Patients With Untreated Pancreatic Cancer May 23, 2017 December 1, 2024
NCT04137536 Active, not recruiting Phase 1 A Study of Armed, Activated T-Cells in Patients With Advanced Pancreatic Cancer October 17, 2019 April 2025
NCT02206360 Active, not recruiting Pancreatic Cancer Early Detection Program April 2014 June 2024
NCT05239182 Active, not recruiting Phase 2 9-ING-41 Plus Retifanlimab and Gemcitabine/Nab-Paclitaxel in Patients With Advanced Pancreatic Adenocarcinoma January 26, 2022 June 30, 2025
NCT03404960 Active, not recruiting Phase 1/Phase 2 Niraparib + Ipilimumab or Nivolumab in Progression Free Pancreatic Adenocarcinoma After Platinum-Based Chemotherapy January 31, 2018 June 2026
NCT02723331 Active, not recruiting Phase 2 Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates December 30, 2016 May 2024
NCT02336087 Active, not recruiting Phase 1 Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery January 14, 2016 December 31, 2024
NCT03483038 Active, not recruiting Phase 2 A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic Adenocarcinoma December 13, 2018 December 2024
NCT03851614 Active, not recruiting Phase 2 Basket Combination Study of Inhibitors of DNA Damage Response, Angiogenesis and Programmed Death Ligand 1 in Patients With Advanced Solid Tumors April 8, 2019 January 1, 2025
NCT03225989 Active, not recruiting Phase 1/Phase 2 Trial Investigating an Immunostimulatory Oncolytic Adenovirus for Cancer March 1, 2018 August 22, 2024
NCT02775786 Active, not recruiting N/A Prospective Evaluation of MRI Biomarkers in Pancreatic Ductal Adenocarcinoma November 2013 December 2025
NCT04257448 Active, not recruiting Phase 1/Phase 2 Safety and Tolerance of Epigenetic and Immunomodulating Drugs Combined With Chemotherapeutics in Patients Suffering From Advanced Pancreatic Cancer May 25, 2020 March 2024
NCT03245541 Active, not recruiting Phase 1/Phase 2 Radiation Therapy in Combination With Durvalumab for People With Pancreatic Cancer August 14, 2020 September 2024
NCT03678883 Active, not recruiting Phase 2 9-ING-41 in Patients With Advanced Cancers January 4, 2019 November 2025
NCT04143152 Active, not recruiting Pancreatic Cancer Biomarker Study January 1, 2021 October 31, 2024
NCT01753479 Completed N/A Spectroscopy From Duodenum January 2013 June 30, 2016
NCT01764477 Completed Phase 1 Safety and Efficacy Study of PRI-724 Plus Gemcitabine in Subjects With Advanced or Metastatic Pancreatic Adenocarcinoma April 2013 October 2015
NCT01764659 Completed 4D-CT for Pancreatic Adenocarcinoma in Radiotherapy Simulation July 2013 October 2014
NCT01765036 Completed N/A Contrast-harmonic Endoscopic Ultrasound (CH-EUS) for the Diagnosis of Pancreatic Adenocarcinoma July 2009 September 2010
NCT01783171 Completed Phase 1 Dinaciclib and Akt Inhibitor MK2206 in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery January 15, 2013 July 12, 2016
NCT01825603 Completed Phase 1 ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer April 9, 2013 June 1, 2017
NCT01834170 Completed Phase 1 EUS-guided Intratumoral Gemcitabine in Locally Advanced Unresectable Pancreatic Cancer April 2013 December 2014
NCT01839799 Completed Phase 2 A Randomized Phase II/Genomic Trial of Two Chemotherapy Regimens in Patients With Resected Pancreatic Adenocarcinoma April 2013 July 2017
NCT06055647 Completed HER-2 Expression in Pancreatic Duct Adenocarcinoma January 1, 2017 December 31, 2020
NCT01959672 Completed Phase 2 Chemotherapy, Stereotactic Body Radiation Therapy & Nelfinavir Mesylate in Locally Advanced Pancreatic Cancer September 6, 2013 December 1, 2018
NCT01989624 Completed PAncreatic Adenocarcinoma in Hospital October 18, 2013 December 2020
NCT02045589 Completed Phase 1 A Phase I Dose Escalation Study of Intratumoral VCN-01 Injections With Gemcitabine and Abraxane® in Patients With Advanced Pancreatic Cancer January 2014 September 2018
NCT02045602 Completed Phase 1 Phase I Dose Escalation Study of Intravenous VCN-01 With or Without Gemcitabine and Abraxane® in Patients With Advanced Solid Tumors January 2014 January 2020
NCT00288093 Completed Phase 1 3-AP and Radiation Therapy in Treating Patients With Stage III Pancreatic Cancer That Cannot Be Removed By Surgery December 20, 2006 December 28, 2012
NCT05305001 Completed Germline Mutations Associated With Hereditary Pancreatic Cancer in Unselected Patients With Pancreatic Cancer in Mexico September 9, 2020 June 30, 2022
NCT02174887 Completed Phase 1 Biological Effect of Nab-paclitaxel Combined to Gemcitabine in Metastatic Pancreatic Cancer September 2014 October 2016
NCT02333188 Completed Phase 1 Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer December 2014 December 2017
NCT05226572 Completed Repeated EUS-guided Fine Needle Biopsy of Pancreatic Masses After Non-diagnostic or Inconclusive Results July 1, 2017 May 23, 2022
NCT02349867 Completed Phase 1 Neoadjuvant Chemotherapy Followed by Radiation Therapy and Gemcitabine/Sorafenib/Vorinostat in Pancreatic Cancer January 29, 2015 May 13, 2022
NCT04992507 Completed Phase 2 Impact of Total Intravenous Anesthesia Following Cancer Surgery, TIVACS Study June 2, 2023 January 26, 2024
NCT02394535 Completed Phase 1 Nab-Paclitaxel, Capecitabine, and Radiation Therapy Following Induction Chemotherapy in Treating Patients With Locally Advanced Pancreatic Cancer November 12, 2015 August 31, 2022
NCT02427841 Completed Phase 2 Nab-paclitaxel and Gemcitabine Hydrochloride Followed by Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery January 21, 2016 December 12, 2022
NCT02514421 Completed Phase 1 Evaluation of Safety and Efficacy of Electrochemotherapy in the Treatment of Pancreatic Adenocarcinoma July 2015 April 18, 2017
NCT02550327 Completed Early Phase 1 Gemcitabine, Nab-Paclitaxel, Cisplatin and Anakinra Treatment on Patients With Pancreatic Cancer January 2016 June 14, 2021
NCT02562716 Completed Phase 2 S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery January 6, 2016 September 26, 2022
NCT02586987 Completed Phase 1 A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid Tumours December 28, 2015 September 20, 2019
NCT00327327 Completed Phase 1 Safety Study of Imexon Plus Gemcitabine in Untreated Pancreatic Adenocarcinoma February 2004 October 2009
NCT02620423 Completed Phase 1 Study of Pembrolizumab With REOLYSIN® and Chemotherapy in Patients With Advanced Pancreatic Adenocarcinoma December 2015 August 2018
NCT02680990 Completed N/A Resilience and Exercise in Advanced Cancer Treatment December 2015 July 2017
NCT04406571 Completed Reorganization of the Healthcare System During COVID-19 Pandemic: Impact on Management of Patients With Exocrine Pancreatic Cancer April 1, 2020 May 31, 2022
NCT04400383 Completed Phase 1 Clinical Trial to Evaluate AB011 Injection in Patients With CLDN18.2-positive Advanced Solid Tumors June 4, 2020 September 28, 2023
NCT04298242 Completed N/A Magnetic Resonance Guided High Intensity Focused Ultrasound in Advanced Pancreatic Adenocarcinoma Treatment November 22, 2020 June 15, 2021
NCT04289961 Completed N/A PDAC Peripheral and Portal Vein Sampling June 12, 2019 April 6, 2023
NCT02749136 Completed Phase 2 Neoadjuvant Modified FOLFIRINOX in Borderline Resectable Pancreatic Cancer May 2016 November 2019
NCT00574977 Completed Phase 1 Safety Study of Modified Vaccinia Virus to Cancer May 2008 July 2014
NCT02806687 Completed Phase 2 Effect of Intratumoral Injection of Gene Therapy for Locally Advanced Pancreatic Cancer January 30, 2017 June 30, 2022
NCT04236102 Completed N/A KEBI-Cyto Study - Use of the Biocartis Idylla July 7, 2020 March 7, 2022
NCT04483349 Completed Assessment of What Patients and Healthcare Providers Value June 11, 2020 August 11, 2022
NCT03665441 Completed Phase 3 Study of Eryaspase in Combination With Chemotherapy Versus Chemotherapy Alone as 2nd-Line Treatment in PAC September 15, 2018 January 18, 2022
NCT03415854 Completed Phase 2 Paclitaxel Protein Bound Plus Cisplatin Plus Gemcitabine and Paricalcitol for Pancreatic Adenocarcinoma (NABPLAGEMD) January 31, 2018 December 11, 2023
NCT03578445 Completed N/A Utility of EUS-guided Microbiopsies in Pancreatic Cystic Lesions February 1, 2018 August 31, 2019
NCT03567863 Completed N/A Study Comparing Pancreatic EUS-FNB With the 20-gauge Procore® and the 22-gauge Acquire® Needles June 24, 2018 September 29, 2019
NCT03559348 Completed Phase 2 Locally Advanced or Metastatic Pancreatic Adenocarcinoma April 3, 2018 April 20, 2020
NCT00638612 Completed Phase 1 AdV-tk Therapy With Surgery and Chemoradiation for Pancreas Cancer (PaTK01) August 2008 June 2015
NCT00644254 Completed The Prognostic Impact of Extracapsular Lymph Node Involvement in Ductal Pancreatic Adenocarcinoma October 2007 March 2008
NCT00769483 Completed Phase 1/Phase 2 MK-0646 and Gemcitabine +/- Erlotinib for Patients With Advanced Pancreatic Cancer November 13, 2008 September 1, 2020
NCT00854477 Completed Phase 4 Pharmacokinetic Study of Adjuvant Capecitabine After Resection of Pancreatic Adenocarcinoma November 2009 August 2012
NCT00909103 Completed Endoscopic Ultrasound Elastography in Pancreatic Masses June 2008 December 2009
NCT01016483 Completed Phase 1/Phase 2 Trial of Gemcitabine With or Without MSC1936369B in Pancreatic Cancer November 30, 2009 April 30, 2015
NCT01144455 Completed Phase 2 Study of the Safety and Efficacy of TH-302 in Combination With Gemcitabine Compared With Gemcitabine Alone in Previously Untreated Patients With Pancreatic Adenocarcinoma June 2010 December 2014
NCT01274455 Completed Phase 1 Gene Therapy of Pancreatic Ductal Adenocarcinoma December 2010 March 2013
NCT00203892 Completed Phase 1/Phase 2 Study of CAP1-6D in Patients With Locally Advanced or Surgically Resected Pancreatic Adenocarcinoma April 2003 May 2012
NCT01369420 Completed Phase 2 NanoKnife Low Energy Direct Current (LEDC) System in Subjects With Locally Advanced Unresectable Pancreatic Cancer May 2011 September 2012
NCT01389440 Completed Phase 2 Efficacy and Safety of a Neoadjuvant Treatment in Pancreatic Cancer May 2011 January 22, 2017
NCT01474564 Completed Feasibility of Obtaining and Characterizing Circulating Tumorigenic Cells in Patients With Pancreatic Adenocarcinoma November 2011 October 2019
NCT01543412 Completed Phase 2 Second Line Chemotherapy for Advanced Pancreatic Cancer January 2010 December 2011
NCT01558869 Completed Phase 2 Xeloxiri as First-line Treatment in Patients With Advanced Unresectable Pancreatic Adenocarcinoma April 2012 December 2016
NCT01660711 Completed Phase 2 A Pilot Study of Pre- and Post-surgery Chemotherapy With mFOLFIRINOX in Localized, Resectable Pancreatic Adenocarcinoma July 2012 August 22, 2018
NCT01674556 Completed Phase 1 Ultrasound-assisted Treatment of Inoperable Pancreatic Cancer February 2012 January 2015
NCT01699698 Completed N/A Pancreatic Juice Diagnosis From Duodenum October 2012
NCT01726582 Completed Phase 2 Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine") November 2011 April 11, 2022
NCT03105921 Completed N/A Irreversible Electroporation (NanoKnife) for the Treatment of Pancreatic Adenocarcinoma October 24, 2014 April 1, 2021
NCT03126435 Completed Phase 3 EndoTAG-1+GEM vs GEM in Patients With Locally Advanced/Metastatic Pancreatic Adenocarcinoma Failed on FOLFIRINOX October 16, 2018 October 8, 2021
NCT03871790 Completed Peptide-based Immunization for Colon- and and Pancreas-carcinoma April 1, 2019 August 31, 2022
NCT03147768 Completed Phase 1 Laser Tissue Welding - Distal Pancreatectomy Sealing Study January 1, 2018 December 31, 2021
NCT03152487 Completed N/A Trial Comparing EUS-guided Radiofrequency Ablation vs. EUS-guided Celiac Plexus Neurolysis April 24, 2017 August 1, 2018
NCT03745430 Completed Phase 1/Phase 2 RAmucirumab Combined wIth Standard Nab-paclitaxel and Gemcitabine as First-line Chemotherapy in Patients With Advanced Pancreatic Adenocarcinoma January 29, 2019 April 23, 2023
NCT03266757 Completed Borderline Resectable or Resectable or Advanced Pancreatic Adenocarcinoma February 11, 2016 February 11, 2018
NCT03307148 Completed Phase 1 Stromal TARgeting for PAncreatic Cancer (STAR_PAC) January 15, 2016 March 19, 2019
NCT03307564 Completed N/A Radiopaque Hydrogel in Patients Undergoing Radiotherapy for Pancreatic Cancer June 6, 2018 December 31, 2022
NCT03318497 Completed Phase 2 Role of Interim 18F-FLT PET/CT for Outcome Prediction in Pancreatic Adenocarcinoma December 11, 2017 June 15, 2021
NCT03329950 Completed Phase 1 A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies December 1, 2017 September 13, 2022
NCT03373188 Completed Phase 1 VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancer December 15, 2017 October 28, 2021
NCT04119362 Completed PARAGON Platform for Outcome, Quality of Life, and Translational Research on Pancreatic Cancer October 24, 2019 June 30, 2023
NCT02896907 Completed Early Phase 1 Ascorbic Acid and Combination Chemotherapy in Treating Patients With Locally Advanced or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery October 18, 2016 March 2019
NCT02896946 Completed N/A Diffusion MRI for Pancreatic Adenocarcinoma February 2011
NCT03054987 Completed N/A Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography for Malignant Distal Biliary Obstruction September 2016 October 2018
NCT00154791 Completed Phase 1/Phase 2 Phase I/II Trial GOFL in Advanced Pancreatic Adenocarcinoma March 2003 August 2005
NCT06102889 Enrolling by invitation GUIDING MULTI-MODAL THERAPIES AGAINST MINIMAL RESIDUAL DISEASE BY LIQUID BIOPSIES May 2, 2024 December 31, 2026
NCT06157671 Enrolling by invitation The LINFU® U.S. Registry for the Detection of Asymptomatic Pancreatic Ductal Adenocarcinoma January 31, 2024 June 1, 2030
NCT04814251 Not yet recruiting Portal Vein Thrombosis Associated With Unresectable Pancreatic Cancers : a Prospective Multicentric Cohort Study March 2021 December 2024
NCT06387342 Not yet recruiting Phase 2 Namodenoson Treatment of Advanced Pancreatic Cancer July 15, 2024 December 15, 2026
NCT06217666 Not yet recruiting Phase 1 Study Examining the Safety and Toxicity of Stereotactic Body Radiotherapy (SBRT) Followed by PCX12 Immunotherapy Delivered by Intratumoral Injection for the Treatment of Patients With Locally Advanced Pancreatic Adenocarcinoma (LAPC) October 31, 2024 January 1, 2028
NCT04835064 Not yet recruiting Phase 3 Pancreatic Cancer With Elevated Serum CA125 Were Compared With Those Who Did Not Receive Neoadjuvant Chemotherapy. April 1, 2021 December 1, 2024
NCT06399757 Not yet recruiting Phase 1/Phase 2 A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors May 2024 May 2027
NCT04926467 Not yet recruiting Phase 2 Chemotherapy + Anakinra in Patients With Pancreatic Adenocarcinoma (PDAC) June 2021 June 2026
NCT06026943 Not yet recruiting N/A Alpha Radiation Emitters Device for the Treatment of Pancreatic Cancer Emitters for the Treatment of Locally Advanced Pancreatic Cancer September 2024 January 2028
NCT06412510 Not yet recruiting Phase 1/Phase 2 Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT June 1, 2024 February 10, 2025
NCT06333314 Not yet recruiting Phase 2 Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI May 2024 September 2030
NCT05287347 Not yet recruiting Panc CA Risk Model & Biomarker Testing In High-Risk Cohort October 2024 October 31, 2027
NCT06440005 Recruiting Phase 1 A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors May 2024 May 2027
NCT01365169 Recruiting N/A Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients" May 25, 2011 June 30, 2027
NCT02070705 Recruiting N/A DCE MRI in Patients With Pancreatic Cancer January 31, 2014 December 31, 2024
NCT02611024 Recruiting Phase 1/Phase 2 Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors May 6, 2016 March 2026
NCT02757859 Recruiting N/A High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery April 27, 2016 January 2025
NCT03073785 Recruiting Phase 2 Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer September 16, 2016 December 2027
NCT03080974 Recruiting Phase 2 Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma August 14, 2017 April 1, 2026
NCT03384238 Recruiting Phase 1/Phase 2 Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery February 7, 2018 September 2027
NCT03715933 Recruiting Phase 1 Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas October 10, 2018 July 2026
NCT03740256 Recruiting Phase 1 Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors December 14, 2020 December 30, 2038
NCT03856658 Recruiting Phase 2 Hepatic Artery Infusional Floxuridine to Treat Pancreatic Cancer Liver Metastases February 5, 2019 April 2026
NCT04002479 Recruiting N/A Alpha Radiation Emitters Device for the Treatment of Advanced Pancreatic Cancer October 20, 2020 October 2026
NCT04098237 Recruiting Phase 2 Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency December 17, 2020 December 2025
NCT04157127 Recruiting Phase 1 Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma August 3, 2020 November 2027
NCT04167007 Recruiting Phase 3 FOLFOX vs Gemcitabine in Patients With Metastatic Pancreatic Cancer Non-fit to FOLFIRINOX July 20, 2020 July 2025
NCT04303403 Recruiting Phase 1 Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma July 31, 2018 March 31, 2024
NCT04361708 Recruiting Phase 1 Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies May 8, 2020 May 2027
NCT04436679 Recruiting INTER-Regional COHORTE of Long Term Pancreatic Cancer Survivors February 2, 2021 February 2025
NCT04452461 Recruiting Phase 2 Pancreatic Adenocarcinoma Neoadjuvant Chemotherapy Before Surgery March 1, 2021 May 1, 2026
NCT04539808 Recruiting Phase 2 NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer May 27, 2021 October 5, 2025
NCT04548752 Recruiting Phase 2 Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations February 22, 2021 March 31, 2025
NCT04605913 Recruiting Phase 1/Phase 2 Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC April 1, 2022 March 2026
NCT04627246 Recruiting Phase 1 Personalized Vaccine With SOC Chemo Followed by Nivo in Pancreatic Cancer September 11, 2020 September 2028
NCT04802876 Recruiting Phase 2 Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors April 12, 2021 March 31, 2027
NCT04895709 Recruiting Phase 1/Phase 2 A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors May 27, 2021 September 15, 2026
NCT04902352 Recruiting N/A The DISSECT Study: Effect of Peri-aDventItial SMA diSsECtion on Margin sTatus During Pancreaticoduodenectomy for Resectable Pancreatic Cancer April 6, 2021 October 6, 2024
NCT04986930 Recruiting Phase 2 mFOLFIRINOX With or Without Stereotactic Body Radiotherapy in Locally Advanced Pancreatic Adenocarcinoma August 14, 2021 August 14, 2025
NCT05000294 Recruiting Phase 1/Phase 2 Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types December 7, 2021 December 2025
NCT05059444 Recruiting ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation September 7, 2021 February 2028
NCT05077800 Recruiting Phase 2 FOLFIRINOX + 9-Ing-41 + Losartan In Pancreatic Cancer March 21, 2022 July 31, 2026
NCT05083247 Recruiting Phase 2 Preoperative mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma March 24, 2023 December 31, 2030
NCT05181605 Recruiting Phase 2/Phase 3 Survival Analysis After Neoadjuvant Therapy in Patients With Resectable Pancreatic Cancer and Risk Factors April 15, 2022 December 1, 2024
NCT05245500 Recruiting Phase 1/Phase 2 Phase 1/2 Study of MRTX1719 in Solid Tumors With MTAP Deletion June 2, 2022 April 30, 2026
NCT05247164 Recruiting N/A EUS-guided PORtal Vein Sampling for Circulating Tumor Cells in Pancreatic Cancer Patients May 17, 2022 March 2027
NCT05268692 Recruiting Phase 2/Phase 3 Neoadjuvant Chemotherapy for Pancreatic Cancer Followed by GS and GnP January 1, 2019 December 31, 2030
NCT05351983 Recruiting N/A Patient-derived Organoids Drug Screen in Pancreatic Cancer September 22, 2022 June 2023
NCT05365581 Recruiting Phase 1 A Study of ASP2138 in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, Pancreatic Cancer June 7, 2022 June 30, 2026
NCT05400681 Recruiting Liquid Biopsy for ctDNA in Peritoneal Lavage and Blood in Pancreatic Cancer August 1, 2020 December 31, 2024
NCT05482516 Recruiting Phase 3 Evaluating Novel Therapies in ctDNA Positive GI Cancers March 29, 2023 December 2028
NCT05494866 Recruiting Phase 1 A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients With Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma December 7, 2022 February 28, 2025
NCT05585320 Recruiting Phase 1/Phase 2 A Phase 1/2a Study of IMM-1-104 in Participants With Previously Treated, RAS-Mutant, Advanced or Metastatic Solid Tumors October 31, 2022 June 2027
NCT05620134 Recruiting Phase 1/Phase 2 Study of JK08 in Patients With Unresectable Locally Advanced or Metastatic Cancer October 17, 2022 February 20, 2026
NCT05624918 Recruiting Phase 2 A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma June 2024 August 2028
NCT05657743 Recruiting N/A A Feasibility and Safety Study of Intratumoral Diffusing Alpha Radiation Emitters for the Treatment of Advanced Pancreatic Cancer August 16, 2023 November 2025
NCT05673811 Recruiting Phase 2 Study of Nab-Paclitaxel and Gemcitabine and Plus/Minus VCN-01 in Patients With Metastatic Pancreatic Cancer January 10, 2023 April 28, 2025
NCT05737706 Recruiting Phase 1/Phase 2 Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation March 20, 2023 August 30, 2026
NCT05752812 Recruiting The HELPP Score: A Pretreatment Score to Predict Survival in Pancreatic Cancer March 1, 2023 November 2026
NCT05776342 Recruiting Prognostic and Predictive Markers of Treatment Response in Patients With PAC. January 1, 2003 December 31, 2031
NCT05795595 Recruiting Phase 1/Phase 2 A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors March 13, 2023 May 2030
NCT05877599 Recruiting Phase 1 A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation July 27, 2023 August 2039
NCT05988918 Recruiting Phase 2 Multicenter Trial of ESK981 in Patients With Select Solid Tumors April 19, 2024 April 2029
NCT06024824 Recruiting Phase 1/Phase 2 Dose-Painted Intensity Modulated Radiotherapy Pancreas (DP-IMRT Pancreas) January 30, 2024 July 2031
NCT06055010 Recruiting Improving Pancreatic Cancer Care by the Use of Computational Science and Technology January 1, 2014 December 31, 2029
NCT06095141 Recruiting Phase 2/Phase 3 Cisplatin to Patients With Pancreatic Cancer and Homologous Recombination Deficiency December 1, 2023 October 31, 2026
NCT06115499 Recruiting Phase 2/Phase 3 The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer December 6, 2023 December 9, 2029
NCT06135649 Recruiting Dissecting the Pattern of Nodal Spread in Post-neoadjuvant Pancreatoduodenectomy January 2013 December 2024
NCT06149689 Recruiting Phase 2 mFOLFIRINOX Plus Radiotherapy to Patients With CA19-9-normal Advanced Pancreatic Cancer January 10, 2024 October 31, 2026
NCT06199895 Recruiting Phase 2 Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer November 28, 2023 November 2025
NCT06219941 Recruiting Phase 2 AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2 December 13, 2023 January 19, 2027
NCT06250972 Recruiting Phase 3 Radiotherapy to Patients With CA19-9-elevated Advanced Pancreatic Cancer May 15, 2024 May 1, 2028
NCT06349044 Recruiting N/A A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies. March 20, 2024 December 31, 2025
NCT06388967 Recruiting Pancreatic Cancer Detection Consortium March 15, 2023 November 21, 2025
NCT06405490 Recruiting Phase 2 NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC April 17, 2024 December 30, 2026
NCT00637364 Suspended Phase 1/Phase 2 High Intensity Focused Ultrasound Tumor Treatment for Pancreatic Cancer Pain March 2008
NCT03784417 Terminated N/A EUS-guided Laser Ablation in Pancreatic Adenocarcinoma October 15, 2019 December 15, 2021
NCT02124369 Terminated Phase 2 Pancreatic Resectability in Cancers With Known Limited Extension (PRICKLE) July 2014 December 2017
NCT00593008 Terminated Phase 1 Temsirolimus in Combination With Gemcitabine in Previously Untreated Metastatic Pancreatic Cancer October 2007 October 2009
NCT02495896 Terminated Phase 1 Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors September 3, 2015 May 29, 2019
NCT02202785 Terminated Phase 2 A Study of MLN0264 in Patients With Pancreatic Cancer July 2, 2014 January 15, 2016
NCT03451773 Terminated Phase 1/Phase 2 M7824 (MSB0011359C) in Combination With Gemcitabine in Adults With Previously Treated Advanced Adenocarcinoma of the Pancreas May 17, 2018 May 5, 2020
NCT04983407 Terminated Phase 1/Phase 2 Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced Pancreatic Adenocarcinoma July 28, 2021 August 14, 2023
NCT02345460 Terminated Phase 2 Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study September 2015 March 2016
NCT04060342 Terminated Phase 1 GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma August 13, 2019 April 11, 2022
NCT04077372 Terminated N/A Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers September 16, 2019 October 11, 2020
NCT05546411 Terminated Phase 2 A Trial of NIS793 With FOLFIRINOX in Pancreatic Cancer January 6, 2023 October 13, 2023
NCT02707328 Terminated Phase 1 Study To Establish Maximum Tolerated Dose (MTD) of Cyberknife in Patients With Un-Resectable Pancreas Cancer (TL002) January 2015 November 10, 2017
NCT05769959 Terminated Phase 1/Phase 2 Study of RO7515629 in Participants With HLA-G Positive Solid Tumors June 15, 2023 March 19, 2024
NCT03592264 Terminated Phase 1/Phase 2 A Phase I/II Study of OBI-3424 in Subjects With Advanced Solid Tumors June 7, 2018 March 21, 2024
NCT02838966 Terminated N/A Preoperative Nutrition With Immune Enhancing Nutritional Supplement (Immunomodulation) August 2014 November 11, 2019
NCT02207985 Terminated Phase 1/Phase 2 Allogeneic Hematopoietic Stem Cell Transplantation in Pancreatic Adenocarcinoma January 2007 June 1, 2017
NCT02638909 Terminated Phase 2 Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies December 2015 March 29, 2018
NCT02376699 Terminated Phase 1 Safety Study of SEA-CD40 in Cancer Patients February 28, 2015 April 14, 2023
NCT01419002 Terminated Phase 3 Study to Evaluate if Neoadjuvant Radiotherapy Improves Recurrence Free Survival in Pancreatic Head Cancer October 2011 October 2014
NCT01206296 Terminated Phase 2 Adjuvant Intraperitoneal Gemcitabine for Resectable Pancreatic Adenocarcinoma August 2010 February 2014
NCT02743975 Terminated Phase 1/Phase 2 Near-infrared Image Guided Surgery in Pancreatic Adenocarcinoma December 1, 2016 May 1, 2018
NCT02736578 Terminated Phase 2 Cetuximab-IRDye 800CW and Intraoperative Imaging in Finding Pancreatic Cancer in Patients Undergoing Surgery July 2016 May 22, 2017
NCT03376659 Terminated Phase 1/Phase 2 Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinoma August 8, 2018 August 1, 2023
NCT06341725 Terminated EUS Role in Non-metastatic Pancreatic Adenocarcinoma Lymph Nodes Staging February 15, 2018 September 11, 2018
NCT01897454 Terminated Phase 2 Gemcitabine Hydrochloride, and Radiation Therapy in Patients With Borderline Resectable Pancreatic Cancer January 27, 2012 November 1, 2021
NCT00598091 Terminated Phase 1 A Phase I/Expansion Study of Dasatinib April 2007 May 2012
NCT03723915 Terminated Phase 2 Pembrolizumab and Pelareorep in Treating Patients With Advanced Pancreatic Cancer November 14, 2018 April 24, 2021
NCT05380557 Terminated ARTEMIS: Study of Patients With Early Stage Pancreatic Cancer Who Have Undergone Genetic Testing August 23, 2021 September 6, 2022
NCT01921751 Terminated Phase 2 High or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and Nab-paclitaxel in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery August 2013 June 2016
NCT04773769 Unknown status N/A Study of Guanábana Leaves for The Treatment of Patients With Gastric, Gastroesophageal Junction, Pancreatic and Colorectal Adenocarcinomas; Hepatocellular Carcinoma, and Low Grade Lymphomas November 7, 2018 November 2023
NCT02072616 Unknown status Phase 3 Detection of Circulating Tumor Cells for the Diagnostic of Pancreatic Adenocarcinoma. September 2014 September 2021
NCT01971281 Unknown status Phase 1/Phase 2 Safety Feasibility and Effect of TTFields (150 kHz) Concomitant With Gemcitabine or Concomitant With Gemcitabine Plus Nab-paclitaxel for Front-line Therapy of Advanced Pancreatic Adenocarcinoma (PANOVA) November 2013 December 2017
NCT03507998 Unknown status Phase 1 Phase 1 Dose Escalation Study of CGX1321 in Subjects With Advanced Gastrointestinal Tumors June 17, 2017 April 1, 2021
NCT03517332 Unknown status Circulating Tumor DNA Exposure in Peripheral Blood January 1, 2015 December 31, 2019
NCT03528785 Unknown status Phase 2 A Study of Nal-IRI With 5-FU, Levofolinic Acid and Oxaliplatin in Patients With Resectable Pancreatic Cancer March 2, 2018 November 1, 2022
NCT03468244 Unknown status N/A Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Digestive System Neoplasms May 1, 2018 December 31, 2021
NCT03570502 Unknown status Incidence of POPF in the Resection of the Left Pancreas With RFAT November 2016 April 2021
NCT03435770 Unknown status N/A Evaluation of Safety and Feasibility of EUS-guided RFA for Solid Pancreatic Neoplasms March 1, 2018 September 1, 2019
NCT03401827 Unknown status Phase 4 The Effect of Gemcitabine Plus Nab-paclitaxel as Secondary Chemotherapy in Advanced Pancreatic Cancer March 1, 2018 January 1, 2019
NCT03673423 Unknown status Evaluation of the Interobserver Agreement on the Resectability Status of Patients With a Pancreatic Cancer September 5, 2018 May 5, 2019
NCT03703063 Unknown status Phase 1 Alternative Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer September 17, 2018 September 17, 2022
NCT03703089 Unknown status Phase 1 Gemcitabine & Nab-Paclitaxel in Pancreatic Adenocarcinoma With Positive Peritoneal Cytology May 1, 2018 May 1, 2023
NCT03221400 Unknown status Phase 1/Phase 2 PEN-866 in Patients With Advanced Solid Malignancies August 29, 2017 June 2023
NCT03202199 Unknown status N/A Neoadjuvant Chemotherapy Response Assessment by Combined PET-MRI in Borderline and Locally Advanced Pancreatic Adenocarcinoma. June 19, 2017 July 1, 2021
NCT03840460 Unknown status A Prospective Translational Tissue Collection Study in Early and Advanced Pancreatic Ductal Adenocarcinoma and Pancreatic Neuroendocrine Tumours to Enable Further Disease Characterisation and the Development of Potential Predictive and Prognostic Biomarkers January 10, 2019 January 10, 2023
NCT03159819 Unknown status N/A Clinical Study of CAR-CLD18 T Cells in Patients With Advanced Gastric Adenocarcinoma and Pancreatic Adenocarcinoma April 1, 2017 December 31, 2021
NCT03140592 Unknown status Pancreatic Cancer Models Developed From EUS Guided Biopsy Tissue January 14, 2015 January 2023
NCT03063554 Unknown status N/A EUS BD vs ERCP TP for Pancreatic Cancer October 18, 2016 October 1, 2018
NCT05228808 Unknown status Immunohistochemical Expression of PD-L1 in Pancreatic Ductal Adenocarcinoma February 1, 2022 December 1, 2022
NCT02839343 Unknown status Phase 2 Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer December 2016
NCT01919151 Unknown status Micrometastasis in Gastrointestinal Cancer June 2008 December 2015
NCT02818829 Unknown status Biological and Clinical Database for Pancreatic Adenocarcinoma March 2014 July 2021
NCT02781012 Unknown status Project Survival-Prospective Biomarker Discovery March 2016 February 2022
NCT04400357 Unknown status N/A Robotic Versus Open Pancreaticoduodenectomy for Pancreatic and Periampullary Tumors June 15, 2020 November 30, 2022
NCT02707315 Unknown status Early Phase 1 A Study of Pre-Operative Cyberknife in Patients With Potentially Resectable Pancreas Cancer January 2013
NCT02133079 Unknown status Phase 1/Phase 2 Immunotherapy of Tumor With Autologous Tumor Derived Heat Shock Protein gp96 March 2012 November 2019
NCT04765410 Unknown status The Impact Of Tissue Micro-RNA Profile From EUS-FNA In Pancreatic Adenocarcinoma March 21, 2019 June 1, 2021
NCT02575508 Withdrawn Phase 1/Phase 2 Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer
NCT03865563 Withdrawn Phase 1 Selective Transvenous Chemoembolization of Primary Pancreatic Tumors July 2019 December 2021
NCT02592395 Withdrawn Phase 1 Study of FOLFIRINOX Electrochemotherapy in the Treatment of Pancreatic Adenocarcinoma October 2015 October 2017
NCT03649035 Withdrawn Phase 3 Eus-guided Cryothermal Ablation in Stage III Pancreatic Adenocarcinoma July 12, 2018 December 31, 2020
NCT05056805 Withdrawn N/A An Exercise and Nutrition Monitoring Intervention (Pt Pal) for the Improvement of Strength in Patients With Pancreatic or Stomach Cancer Receiving Chemoradiation Therapy Before Surgery, SurgeryStrong Study March 4, 2021 September 8, 2022
NCT00728000 Withdrawn Phase 2 Phase II Study Of Neoadjuvant Chemotherapy In Borderline Resectable Pancreatic Adenocarcinoma August 2008 August 2010
NCT04270929 Withdrawn Phase 1 Pressure Enabled Drug Delivery By Pancreatic Retrograde Venous Infusion For Advanced Pancreatic Carcinoma December 23, 2019 May 4, 2021
NCT04130399 Withdrawn Phase 2 Study of Neoadjuvent Chemotherapy Followed by SBRT in Patients With Resectable and Borderline Resectable Pancreatic Cancer July 1, 2019 January 1, 2023
NCT02496832 Withdrawn N/A A Study of Hypoxia Imaging in Advanced Pancreatic Cancer Patients Being Treated With Gemcitabine and TH-302 or TH-302 Placebo November 2014 November 2014
NCT02850874 Withdrawn Phase 2 HIPEC as Neoadjuvant Treatment for Resectable Pancreatic Adenocarcinoma February 2016 December 2016
Disase is a (Disease Ontology)
DOID:4905
Cross Reference ID (Disease Ontology)
NCI:C8294
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:700423003
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0281361
Exact Synonym (Disease Ontology)
pancreas adenocarcinoma
Disase Synonym (Disease Ontology)
adenocarcinoma of the pancreas
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0006725