epidermolysis bullosa dystrophica
Information
- Disease name
- epidermolysis bullosa dystrophica
- Disease ID
- DOID:4959
- Description
- "An epidermolysis bullosa that is characterized by formation of recurrent blisters secondary to minor trauma in the skin and mucosa, especially in the hands, feet, knees, and elbows, and has_material_basis_in mutation in COL7A1 gene, which encodes a protein that assists assembly of type VII collagen." [url:https\://ghr.nlm.nih.gov/condition/dystrophic-epidermolysis-bullosa#genes]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05843994 | Active, not recruiting | Artificial Intelligence Patient App for RDEB SCCs | February 13, 2023 | June 30, 2024 | |
| NCT04171661 | Active, not recruiting | Early Phase 1 | Self-Assembled Skin Substitute for the Treatment of Epidermolysis Bullosa | December 10, 2019 | December 10, 2024 |
| NCT00951964 | Completed | Phase 2 | Treatment of Epidermolysis Bullosa Dystrophica by Polyphenon E (Epigallocatechin 3 Gallate) | October 2010 | July 2013 |
| NCT01263379 | Completed | Phase 1/Phase 2 | Gene Transfer for Recessive Dystrophic Epidermolysis Bullosa | October 5, 2010 | March 9, 2022 |
| NCT01716169 | Completed | N/A | Treatment of Chronic and Non-Chronic Wounds in Patients With Recessive Dystrophic Epidermolysis Bullosa Using Helicoll Collagen Dressings Versus Standard of Care | October 2012 | November 2013 |
| NCT03241628 | Completed | Proof of Concept Study for a Dressing Glove | May 3, 2017 | January 31, 2018 | |
| NCT00904163 | Completed | Characteristics of Adult Patients With Recessive Dystrophic Epidermolysis Bullosa | April 2009 | May 2014 | |
| NCT04908215 | Completed | Phase 2 | INM-755 (Cannabinol) Cream for Treatment of Epidermolysis Bullosa | December 28, 2021 | April 19, 2023 |
| NCT06177353 | Not yet recruiting | Study of the Blood and Skin Immunological Profile of Patients With Recessive Dystrophic Epidermolysis Bullosa: in Vivo Analysis and the Impact of Placental Stem Cells in Vitro | March 1, 2024 | March 1, 2025 | |
| NCT03786237 | Recruiting | Phase 1/Phase 2 | Rigosertib for RDEB-SCC | April 12, 2021 | June 2026 |
| NCT01019148 | Recruiting | Characteristics of Patients With Recessive Dystrophic Epidermolysis Bullosa | November 10, 2009 | December 31, 2025 | |
| NCT03269474 | Recruiting | Computational Drug Repurposing for All EBS Cases | November 28, 2017 | December 31, 2024 | |
| NCT06007235 | Recruiting | N/A | CACIPLIQ20 in Wound Healing in Subjects With Epidermolysis Bullosa | January 29, 2024 | September 2024 |
| NCT00533572 | Terminated | Recessive Dystrophic Epidermolysis Bullosa Screening for Possible Gene Transfer | August 2007 | August 2008 | |
| NCT00587223 | Terminated | Phase 3 | Safety and Efficacy of Apligraf in Nonhealing Wounds of Subjects With Junctional or Dystrophic Epidermolysis Bullosa (EB) | December 2007 | December 2008 |
| NCT05033574 | Unknown status | The State of Sexual Development in Children With Inherited Epidermolysis Bullosa | December 8, 2020 | June 1, 2023 | |
| NCT05390073 | Unknown status | Growth Hormone in EB | May 25, 2022 | June 15, 2022 | |
| NCT04213703 | Unknown status | A Pilot Study to Explore the Role of Gut Flora in Epidermolysis Bullosa | March 2, 2020 | July 2023 |
- Disase is a (Disease Ontology)
- DOID:2730
- Cross Reference ID (Disease Ontology)
- GARD:2150
- Cross Reference ID (Disease Ontology)
- ICD10CM:Q81.2
- Cross Reference ID (Disease Ontology)
- MESH:D016108
- Cross Reference ID (Disease Ontology)
- NCI:C84691
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:254185007
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0079294
- Exact Synonym (Disease Ontology)
- Dystrophic epidermolysis bullosa
- ICD10 preferred id (Insert disease from ICD10)
- D0014101
- ICD10 class code (Insert disease from ICD10)
- Q81.2
- MeSH unique ID (MeSH (Medical Subject Headings))
- D016108