substance dependence

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Information
Disease name
substance dependence
Disease ID
DOID:9973
Description
"A substance-related disorder that involves the continued use of alcohol or other drugs despite problems related to use of the substance." [url:http\://en.wikipedia.org/wiki/Drug_dependence]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT01621711 Active, not recruiting N/A Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care March 2011 December 31, 2025
NCT04768920 Active, not recruiting N/A Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD) November 11, 2022 February 28, 2026
NCT00208195 Completed Phase 4 Depakote ER Therapy for Mania Comorbid With Substance Abuse March 2004 November 2007
NCT00227838 Completed N/A Modifying Group Therapy for Bipolar Substance Abusers - 1 July 2003 August 2005
NCT00288886 Completed Phase 2 Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment March 2007 June 2011
NCT00295139 Completed N/A Behavioral Treatment of Drug Abuse in Severe and Persistent Mental Illness (SPMI) Patients January 2005 March 2010
NCT00430482 Completed N/A Stress, Distress Intolerance, and Drug Dependence June 2005 July 2011
NCT00437632 Completed Phase 1 Study To Investigate If Repeat Doses Of GSK598809 Are Safe And Well Tolerated And To Evaluate Blood Levels Of GSK598809 March 1, 2007 August 22, 2008
NCT00437840 Completed Phase 1 A Study To Investigate The Safety, Tolerability And Blood Levels Of GSK598809 March 20, 2007 June 20, 2007
NCT00484692 Completed Phase 4 Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation July 2005 January 2007
NCT00513279 Completed Phase 1 To Investigate If Single Doses Of GSK618334 Are Safe And To Investigate Blood Levels Of GSK618334 June 28, 2007 October 4, 2007
NCT00604188 Completed Phase 4 A Randomized Acceptability and Safety Study of Suboxone Induction in Heroin Users (P05042)(COMPLETED) February 22, 2008 December 10, 2009
NCT00057187 Completed N/A Improving Substance Abuse Treatment Aftercare Adherence and Outcome January 2005
NCT00606996 Completed Phase 2 Group Therapy for Women Prisoners With Comorbid Substance Use and Depression July 2006 December 2009
NCT00657397 Completed Phase 3 Initialization of Methadone in Primary Care, Randomized Intervention Research for Preventing HCV Transmission Practices January 2009 December 2011
NCT00728052 Completed Phase 1 A Human Volunteer Study Investigating Single Oral Doses of GSK598809 in Otherwise Healthy Smokers June 9, 2008 August 19, 2008
NCT00728897 Completed Phase 1 A Healthy Volunteer Study to Investigate the Relative Bioavailability of Two Forms of GSK598809 Capsules. July 2, 2008 July 29, 2008
NCT00605241 Completed Phase 1 A Study To Assess The Effects Of A Single Dose Of GSK598809 In Modulating Nicotine Reward February 25, 2008 March 20, 2009
NCT00208143 Completed Phase 4 Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia November 2003 December 2005
NCT01011907 Completed N/A A Pilot Clinical Trial of Varenicline as a Treatment for Alcohol Dependence January 2010 June 2012
NCT01036061 Completed Phase 1 GSK618334 Repeat Dose Study September 28, 2009 February 17, 2010
NCT01039454 Completed Phase 1 Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement December 18, 2008 April 26, 2010
NCT01128140 Completed Phase 2 Efficacy Trial of Warrior Check-Up October 2010 September 2014
NCT01189799 Completed N/A Motivational Therapy for Substance Users With Depression September 2007 January 2013
NCT01305629 Completed N/A Intervention Targeting Substance Using Older Adults With HIV June 2011 June 2016
NCT01320748 Completed N/A fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults February 2011 January 2013
NCT01381133 Completed Phase 3 Adolescent Outpatient and Continuing Care Study September 2002 December 2008
NCT01410110 Completed Phase 2 Cognitive Remediation and Work Therapy in the Initial Phase of Substance Abuse Treatment December 2010 December 2014
NCT01550887 Completed N/A Evaluation of Impulsivity on Cocaine and Crack Addicts April 2012 May 2015
NCT01634347 Completed Phase 2 Memory Reconsolidation Blockade for Treating Drug Addiction January 2012 May 2014
NCT02461732 Completed N/A Trial of a Novel Cognitive-Behavioral Treatment for Posttraumatic Stress and Substance Dependence August 2014 November 2016
NCT03000699 Completed N/A Efficacy of Cognitive Bias Modification in Residential Treatment for Addiction March 1, 2017 December 31, 2018
NCT03048552 Completed N/A Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3 November 17, 2016 December 1, 2018
NCT03767907 Completed N/A Online Cognitive Behavioural Therapy for Addiction: Efficacy and Cost-Effectiveness in a Pragmatic Clinical Trial October 1, 2018 December 31, 2021
NCT00814957 Completed Phase 1 An Open Label Positron Emission Tomography (PET) Study of GSK618334 in Healthy Male Subjects Using 11C-PHNO as PET Ligand December 8, 2008 June 11, 2009
NCT00887367 Completed Phase 1 EtOH Interaction Study September 29, 2008 December 3, 2008
NCT05312359 Not yet recruiting N/A Brain Mechanism and Intervention of Executive-control Dysfunction Among Substance Dependents June 1, 2022 December 31, 2025
NCT04430257 Recruiting N/A Pre-exposure Prophylaxis (PrEP) for Health September 2, 2021 July 1, 2025
NCT05348317 Recruiting N/A Developing a Telehealth Model to Improve Treatment Access for Rural Veterans With Substance Use Disorders May 19, 2022 September 30, 2026
NCT05410561 Recruiting N/A Harnessing Telemedicine to Improve Alcohol Use Disorder Outcomes in Primary Care Patients November 1, 2022 February 28, 2026
NCT05679284 Recruiting A Cross-Sectional Observational Study on Retained Drug Needle Fragments in People Who Use Intravenous Drugs May 25, 2023 November 15, 2028
NCT05833399 Recruiting Correlation of Genetic Variations With Clinical Response in Substance Use Disorder November 28, 2022 December 2024
NCT00609089 Unknown status Phase 1/Phase 2 Community Reinforcement and Family Training for Drug Abuse Treatment Retention/HIV Risk Reduction March 2008 June 2013
NCT01314378 Unknown status N/A Effects of Intensive Behavioral Training Program on Impulsivity and Inhibitory Control in Smokers January 2011 October 2012
NCT00630097 Unknown status Phase 2 A Dose Ranging Study of Modafinil for Methamphetamine Dependence December 2009 June 2011
NCT01741415 Unknown status Phase 2 Distress Tolerance Treatment for Substance Users May 13, 2013 September 1, 2019
NCT00908206 Withdrawn Phase 1 Effects of GSK598809 on Brain Activation in Abstinent Alcoholics May 2009 July 2009
NCT01515917 Withdrawn N/A Citicoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI) November 2013 July 2017
NCT01155544 Withdrawn Phase 4 Improving Outcomes in Psychosis Associated With Substance Use Using Aripiprazole June 2011 June 2014
NCT03762798 Withdrawn N/A Can The Bridge Transition Opiate Use Disorder Patients in Stable Recovery From Buprenorphine to Naltrexone November 19, 2018 December 1, 2020
NCT00793468 Withdrawn Phase 2 Relapse Prevention Study in Newly Abstinent Smokers December 2008 December 2008
Disase is a (Disease Ontology)
DOID:303
Cross Reference ID (Disease Ontology)
NCI:C35458
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:255338002
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0439857