Renal Insufficiency

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Information
Disease name
Renal Insufficiency
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05418816 Active, not recruiting N/A SelfWrap-Assisted Arteriovenous Fistulas June 14, 2021 August 2024
NCT04876963 Active, not recruiting HOLT-ED: Holter-monitoring in End-stage Renal Disease September 1, 2021 September 5, 2024
NCT03672110 Active, not recruiting Phase 3 Slow and Low Start of a Tacrolimus Once Daily Immunosuppressive Regimen September 2014 December 2025
NCT00186329 Completed Phase 4 BNP for Cardio-Renal Decompensation Syndrome (BNP-CARDS) March 2004 October 2006
NCT00187330 Completed Phase 2 A Study of The Effectiveness of N-Acetylcysteine in Kidney Protection Following Cardiopulmonary Bypass March 2004 August 2005
NCT00264693 Completed Pharmacokinetics of Dalteparin in Patients With Impaired Renal Function January 2006 May 2008
NCT00119691 Completed Phase 2 Nesiritide Infusion for the Treatment of Decompensated Heart Failure and Renal Dysfunction April 2003 November 2005
NCT00138099 Completed Dalteparin's Influence on Renally Compromised: Anti-Ten-A Study (DIRECT) July 2004 June 2006
NCT00159614 Completed Phase 2 Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With CHF and Renal Impairment September 2005
NCT02191228 Completed Phase 1 Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Single and Multiple Doses of Linagliptin Tablets in Patients With Different Degrees of Renal Impairment in Comparison to Subjects With Normal Renal Function April 2008
NCT02263820 Completed Novel Biomarkers for Risk Prediction of Contrast-Induced Acute Kidney Injury Post Coronary Angiography January 2015 December 2016
NCT02314403 Completed Phase 1 Renal Allograft Tolerance Through Mixed Chimerism (Belatacept) February 2015 July 2021
NCT02320045 Completed Phase 1 Study to Evaluate Pharmacokinetics of ITCA 650 in Subjects With Renal Impairment Compared to Normal Subjects November 2014 July 2015
NCT02332070 Completed Timing of Coronary Angiography, Cardiac Surgery, and Adverse Renal and Cardiac Events (MARCE) January 2015 February 2018
NCT02347046 Completed Phase 1 Clinical Pharmacology of FYU-981 (Subjects With Renal Insufficiency) January 2015 March 2015
NCT02355704 Completed Phase 3 Anti-inflammatory Effect of Atorvastatin on Graft Donor Kidney January 2012 July 2014
NCT02458248 Completed Phase 2 Sodium Intake in Chronic Kidney Disease (STICK) March 2016 August 2020
NCT02463604 Completed N/A Renal PRotection Against Contrast mEdium-induced nephroPathy in High Risk Patients undErgoing Coronary Angiography June 2015 March 24, 2017
NCT02468440 Completed N/A Evaluation of ESPAIR, an Educational Therapy's Program of Patients With Renal Insufficiency Before Kidney Transplant June 2, 2015 January 14, 2019
NCT02477488 Completed Phase 4 Optimal Administration of Allopurinol in Dialysis Patients June 2015 August 2015
NCT02479165 Completed Phase 4 Pain Management After Cardiac Surgery - Opioids or NSAID May 2009 September 2013
NCT02492620 Completed Phase 3 Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D March 2015 November 2017
NCT02522117 Completed Phase 3 Atorvastatin in the Recipient's Kidney Graft From a Living Donor August 2015 January 2018
NCT02603614 Completed Phase 1/Phase 2 Safety Study of Cenderitide in Chronic Stable Heart Failure With Moderate Renal Impairment December 2015 March 31, 2016
NCT02653014 Completed Phase 1 Safety, Tolerability and Pharmacokinetics of KBP-5074 in Healthy Subjects and Subjects With Renal Impairment July 29, 2015 March 28, 2017
NCT02668250 Completed N/A Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality February 3, 2017 March 16, 2021
NCT02780414 Completed Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers January 2016 October 23, 2020
NCT02815774 Completed Phase 1 SP2086 Pharmacokinetic Study in Renal Insufficiency Patients June 2014 January 2015
NCT02849964 Completed Factors Related to Geographical Variation in the Incidence of End-stage Renal Failure: An Analysis in 5 French Regions September 2015 June 2016
NCT02872155 Completed Phase 3 Comparative Study of the Efficacy of Oral Versus Intravenous Hydration as a Preventive Measure of Contrast-induced Nephropathy (CIN) in Patients With Renal Insufficiency (RI) Grade III Under Study Conducting Computed Tomography (CT) July 4, 2017 July 15, 2019
NCT02894385 Completed Phase 1 Effect of Hepatic and Renal Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1841788 (ODM-201) September 13, 2016 December 15, 2017
NCT02894905 Completed Phase 1 A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335 September 13, 2016 August 16, 2017
NCT02961660 Completed Phase 1 A Study to Evaluate the Effect of Severe Renal Impairment on the Single-dose Pharmacokinetics of Odalasvir November 9, 2016 April 9, 2018
NCT03087942 Completed Phase 1 Pharmacokinetics and Safety of Fevipiprant in Patients With Renal Impairment Compared to Matched Healthy Subjects July 5, 2017 August 7, 2018
NCT03095391 Completed The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of FAST PV and mGFR Technology™ June 13, 2017 September 20, 2017
NCT03097016 Completed Phase 1 A Study to Assess the Pharmacokinetics of CC-122 in Subjects With Mild, Moderate, and Severe Renal Impairment March 30, 2017 December 23, 2017
NCT03102996 Completed Phase 4 Preserve-Transplant Study June 12, 2017 July 26, 2021
NCT03108924 Completed Phase 1 The Pharmacokinetics of Gefapixant (MK-7264) in Participants With Renal Insufficiency (MK-7264-026) April 14, 2017 September 13, 2017
NCT03112499 Completed N/A The Effect of Three Endourological Procedures for the Management of Renal Calculi Regarding Acute Kidney Injury June 5, 2018 June 15, 2021
NCT03157414 Completed Phase 4 Empagliflozin in Renal Transplant Recipients November 7, 2016 June 28, 2018
NCT03189498 Completed Phase 1 A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of JNJ-64041575 in Adult Participants With Various Degrees of Renal Function July 11, 2017 December 6, 2017
NCT03235375 Completed Phase 1 A Study to Evaluate Pharmacokinetics, Safety and Tolerability of MEDI0382 in Renal Impairment Subjects October 27, 2017 April 24, 2018
NCT03302091 Completed Phase 1 A Study in People With Normal Kidney Function and People With Reduced Kidney Function to Test How BI 1467335 is Processed in the Body October 17, 2017 August 16, 2018
NCT03311841 Completed Phase 1 Pharmacokinetics of Midazolam, Dabigatran, Pitavastatin, Atorvastatin, and Rosuvastatin in Participants With Renal Insufficiency in the Presence and Absence of Rifampin (MK-0000-386) March 1, 2018 August 2, 2018
NCT03347032 Completed N/A Remote Ischemic Preconditioning for Renal Protection in TAVI February 13, 2018 December 30, 2018
NCT03355742 Completed N/A XIENCE 28 Global Study February 9, 2018 April 30, 2020
NCT03482024 Completed Phase 1 A Study of Tirzepatide (LY3298176) in Participants With Impaired Kidney Function March 30, 2018 August 19, 2019
NCT03532919 Completed Heart and Renal Failure in Hip Fracture Surgery February 1, 2018 December 1, 2018
NCT03550378 Completed Phase 2 A Study to Look at the Effect MEDI0382 Has on Blood Sugar in People With Type 2 Diabetes and Kidney Problems and Also to Check That MEDI0382 is Well Tolerated June 29, 2018 February 4, 2019
NCT03632915 Completed Pharmacokinetics of Antiepileptics in Patients on CRRT November 20, 2017 December 31, 2019
NCT03657784 Completed Phase 1 Pharmacokinetics, Dialysability and Safety of P03277 in Healthy Volunteers and in Patients With Impaired Renal Function October 13, 2017 August 23, 2019
NCT03667300 Completed Phase 2 Effect of Evogliptin on Albuminuria in Patients With Type 2 Diabetes and Renal Insufficiency March 16, 2017 May 14, 2019
NCT03814005 Completed Phase 1 A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems July 10, 2019 April 19, 2022
NCT03815175 Completed N/A XIENCE 28 USA Study February 25, 2019 February 4, 2021
NCT03844555 Completed Phase 1 Elafibranor Pharmacokinetic Parameters in Renal Impaired Patients February 28, 2019 March 21, 2020
NCT03916861 Completed N/A BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy October 1, 2017 February 28, 2018
NCT03974646 Completed N/A Effectiveness of Chronic Kidney Disease Nurse-led Self-management Program (CKD-NLSM) June 1, 2020 August 31, 2022
NCT04024332 Completed Phase 1 Study of the Way the Body Takes up, Distributes, and Gets Rid of ACT-541468 in Subjects With Abnormal Kidney Function Compared to Healthy Subjects September 24, 2019 August 14, 2020
NCT04043871 Completed Concordance Between the Foot-to-Apex Systolic Interval and the Auscultatory Method for Measurement of Brachial Systolic Pressure in Patients With Severe Renal Failure June 5, 2019 August 14, 2019
NCT04154670 Completed Phase 1 Study Assessing PK and Safety of MGTA-145 in Subjects With Normal Estimated GFR and Varying Degrees of Renal Impairment November 7, 2019 March 24, 2020
NCT04170309 Completed Collection of Data of Ceftobiprole Treated Patients: Comparison of Patients With and Without Certain Diseases March 30, 2020 June 9, 2023
NCT04193865 Completed Hemofilter Life Span, ECLS and/or CRRT January 9, 2020 March 25, 2024
NCT04348175 Completed Phase 1 A Phase 1 Study to Evaluate the Pharmacokinetics of Setmelanotide in Subjects With Varying Degrees of Renal Impairment July 9, 2020 April 17, 2021
NCT04445558 Completed N/A Study of 2 Modalities of Dialysis and Nutrition on the Nutritional Status of Malnourished Chronic Renal Disease Patients July 21, 2020 June 4, 2021
NCT04486625 Completed Phase 1 Pharmacokinetic Study of Aztreonam-Avibactam in Severe Renal Impairment August 10, 2020 October 18, 2021
NCT04736329 Completed N/A Telmisartan Versus Enalapril in Heart Failure With Reduced Ejection Fraction Patients With Moderately Impaired Kidney Functions February 1, 2021 October 31, 2022
NCT04788394 Completed Renal Involvement in Hospitalized Children With COVID-19 March 1, 2021 December 31, 2021
NCT04922645 Completed Phase 4 Auryxia (Ferric Citrate) Therapy for In-Center and Home Dialysis Participants June 29, 2021 September 15, 2022
NCT04933747 Completed Phase 1 Study to Evaluate Safety and Tolerability of Iberdomide (CC-220) in Participants With Kidney Impairment Compared to Participants With Normal Kidney Function August 12, 2021 January 23, 2023
NCT05283746 Completed Phase 1 A Study of Epetraborole Tablets in Subjects With Degrees of Renal Function February 21, 2022 June 27, 2022
NCT05455528 Completed Preoperative Renal Insufficiency Predicts Postoperative Adverse Outcomes January 1, 2022 July 1, 2022
NCT05469100 Completed Phase 1 A Study of Effect of Selpercatinib (LY3527723) in Participants With Normal and Impaired Renal Function December 19, 2018 August 7, 2019
NCT05488899 Completed N/A Ultra Low Iodine Loaded Spectral CT Angiography (CTA) January 28, 2019 October 16, 2020
NCT05611957 Completed Phase 1 A Study of LY3437943 in Healthy Participants and Participants With Impaired Renal Function November 16, 2022 September 5, 2023
NCT05624710 Completed Phase 1 A Study to Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment December 8, 2022 June 30, 2023
NCT05624723 Completed Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis January 12, 2023 February 7, 2024
NCT05630326 Completed Association Between COVID-19 and UTIs Caused by ESBL Organism in Infants March 1, 2023 July 20, 2023
NCT05718648 Completed Phase 1 A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Kidney Problems February 9, 2023 August 15, 2023
NCT05718843 Completed Phase 1 A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Kidney Problems February 1, 2023 October 24, 2023
NCT05841277 Completed Phase 1 A Study of LY3819469 in Participants With Impaired and Normal Renal Function April 25, 2023 January 9, 2024
NCT05936138 Completed Phase 1 A Study of LY3502970 in Participants With Normal and Impaired Renal Function July 13, 2023 April 11, 2024
NCT05970094 Completed N/A Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5 March 6, 2023 November 20, 2023
NCT05990660 Completed N/A Renal Assist Device (RAD) for Patients With Renal Insufficiency Undergoing Cardiac Surgery September 28, 2023 January 18, 2024
NCT06070337 Completed N/A H-Guard Pilot Safety Evaluation in Haemodialysis Patients October 19, 2023 February 29, 2024
NCT06190678 Completed Phase 1 Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Kidney Function and Healthy Participants February 1, 2021 June 4, 2021
NCT00413088 Completed Phase 1 Study to Assess Bemiparin Pharmacokinetics in Renal Insufficiency and in the Elderly March 2006 March 2011
NCT00418366 Completed Phase 1 A Study on the Effect of Kidney Disease on a Diabetes Medication (0431-008) January 2003 March 2003
NCT00465140 Completed N/A Effects of Creatine Supplementation on Renal Function January 2004 January 2007
NCT00501462 Completed Phase 1 A Comparison Of Study Drug Blood Levels After One Dose Of GSK189075 In Subjects With Normal And Reduced Kidney Function July 2007 March 2008
NCT00566033 Completed Phase 4 Multiple Intervention and AUdit in Renal Diseases to Optimize Care January 2006 August 2011
NCT00580047 Completed N/A Effects of Zoledronic Acid Versus Alendronate on Bone Loss After Kidney and Kidney/Pancreas Transplants December 1, 2003 July 29, 2014
NCT00600834 Completed Evaluation of the Risk of NSF Following ProHance Injection in Patients With Chronic Kidney Disease February 2008 May 2013
NCT00600951 Completed Evaluation of the Risk of NSF Following MultiHance Injection in Patients With Chronic Kidney Disease January 2008 August 2013
NCT00621712 Completed N/A Clinical Assessment of a New Catheter Surface Coating With Antimicrobial Properties October 2007 December 2010
NCT00650845 Completed Phase 4 Renal Safety Evaluation After Dotarem®-Enhanced MRI January 2008 August 2011
NCT00709865 Completed Phase 3 Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency July 31, 2008 December 31, 2009
NCT00721734 Completed Phase 2 Study of the Safety and Pharmacokinetics of Carfilzomib in Patients With Relapsed and Refractory Multiple Myeloma and Varying Degrees of Renal Function November 2008 November 2012
NCT00731523 Completed Phase 1 Pharmacokinetics (PK) and Metabolism of FTY720 in Patients With Severe Renal Impairment and Healthy Matched Subjects. July 2008
NCT00744939 Completed Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Moderate Renal Insufficiency After the Administration of Magnevist November 2008 November 2013
NCT00765830 Completed Phase 3 Safety and Tolerability of Vildagliptin Versus Placebo in Patients With Type 2 Diabetes and Moderate or Severe Renal Insufficiency (28 Week Extension) September 2008 April 2011
NCT00770081 Completed Phase 3 Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency (28-week Extension Study) September 2008 April 2011
NCT00773409 Completed Evaluation of the Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Without Exposure to Gadolinium Based Contrast Agents (GBCA) October 2008 July 2012
NCT00774137 Completed Examining New Diagnostic Tests for Acute Kidney Injury After Heart Surgery April 2007 February 2014
NCT00892749 Completed Phase 3 Long-term Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis May 2009 September 2010
NCT00908310 Completed Phase 4 Post-marketing Safety Study in Patients With Moderate Renal Insufficiency Who Receive Omniscan for Contrast-enhanced Magnetic Resonance Imaging (MRI) May 2009 September 2013
NCT00911625 Completed Phase 4 Glargine Dosing in Hospitalized Patients With Type 2 Diabetes and Renal Insufficiency January 21, 2009 June 30, 2011
NCT01017276 Completed Phase 3 A Phase 3 Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Peritoneal Dialysis November 2009 September 2010
NCT01028170 Completed Phase 3 Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart Failure November 2009 January 2012
NCT01057407 Completed Phase 3 A Comparative Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia on Hemodialysis January 2010 September 2010
NCT01064414 Completed Phase 3 An Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus Who Have Moderate Renal Impairment June 2010 August 2012
NCT01101087 Completed N/A Taurolock for Preventing Bacterial Peritonitis During Renal Insufficiency July 2010 December 2015
NCT01119781 Completed Phase 1 A Single-Dose, Pharmacokinetic/Pharmacodynamic (PK/PD), & Safety Study of BIIB017 in Participants With Renal Impairment & Healthy Volunteers May 2010 August 2011
NCT01121770 Completed Phase 1 "Pharmacokinetic Study of Fondaparinux in Inpatients With Renal Dysfunction" May 2010 February 2013
NCT01164501 Completed Phase 3 Efficacy and Safety of Empagliflozin (BI 10773) in Patients With Type 2 Diabetes and Renal Impairment July 2010 July 2012
NCT01172431 Completed Phase 4 Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal Insufficiency September 2010 December 2013
NCT01207297 Completed Phase 1 Tacrolimus Versus Cyclophosphamide as Treatment for Lupus Nephritis March 2003 June 2010
NCT01231997 Completed Phase 1 Clinical Study to Investigate the Safety and Pharmacokinetics of Udenafil Tablet in Renal Impaired Male Patients November 2009
NCT01232010 Completed Phase 1 Clinical Study to Investigate the Safety and Pharmacokinetics of SK3530 Tablet in Renal Impaired Male Patients November 2009
NCT01289548 Completed N/A Effect of Remote Ischaemic Preconditioning on Renal Function in Patients Undergoing Living Donor Kidney Transplantation May 2010 January 2012
NCT01309438 Completed Phase 1 A Study of Erythromycin and Rivaroxaban in Study Participants With Normal and Reduced Kidney Function February 2011 March 2012
NCT01316055 Completed Phase 1 Pharmacokinetics (PK) of Dalfampridine-ER 7.5 mg BID in Healthy Volunteers and Subjects With Mild or Moderate Renal Impairment January 2011 September 2011
NCT01323075 Completed Pharmacodynamic Comparison of Truncal Blocks in Patients With or Without Metabolic Disease (Kidney Failure, Diabetes) May 2011 December 2013
NCT01337752 Completed Phase 2 Study in Patients With Untreated Multiple Myeloma and Renal Insufficiency January 2012 May 2013
NCT01373775 Completed Risk Factors of the Revisit of the Adult Heart Failure Patients in Emergency Department Siriraj Hospital April 2009 February 2010
NCT01403766 Completed Comparison of Markers of Kidney Function August 2011 December 2012
NCT01407874 Completed Phase 2 A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency September 2011 July 2012
NCT01424176 Completed Phase 1 Dexpramipexole Renal PK Study July 2011 January 2012
NCT01432535 Completed Phase 1 Pharmacokinetics of Peginterferon Alfa-2b in Participants With Moderate and Severe Renal Impairment (P05655) November 2011 August 2012
NCT01453218 Completed Phase 3 Safety Use of ATeGe in Liver Transplant Recipients With Pre-transplant Renal Dysfunction October 2011 February 2020
NCT01462136 Completed Phase 1 PK Study of ACHN-490 Injection in Renally Impaired Subjects September 2011
NCT01467271 Completed Observational Study on the Incidence of NSF in Renal Impaired Patients Following Dotarem Administration May 2011 June 2017
NCT01512667 Completed Phase 1 Pharmacokinetic Assessment of Single-Dose Odanacatib (MK-0822) in Subjects With Severe Renal Insufficiency (MK-0822-067) January 17, 2012 August 22, 2012
NCT01522313 Completed Influence of Perioperative Kidney Function on Postoperative Outcome January 2006 June 2012
NCT01545531 Completed Two-Point Measurement of Glomerular Filtration Rate by Iohexol Plasma Disappearance September 2008 January 2016
NCT01560572 Completed Phase 4 Steroid Free Immunosuppression or Calcineurin Inhibitor Minimization After Basiliximab Induction Therapy in Kidney Transplantation: Comparison With a Standard Quadruple Immunosuppressive Regimen April 2011 April 2016
NCT01658514 Completed Phase 2 Assessing the Behavior of Met DR in Subjects With Kidney Dysfunction January 2014 June 2014
NCT01660295 Completed Phase 1/Phase 2 Pharmacokinetics of Certoparin in Subjects With Renal Insufficiency and Healthy Subjects December 2011
NCT01715259 Completed Phase 1 A Pharmacokinetic Study of Abiraterone Acetate in Male Participants With Impaired Renal Function Compared to Individuals With Normal Renal Function August 2009 January 2010
NCT01742585 Completed Phase 3 A Phase 3 Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia Not on Dialysis October 2012 May 2014
NCT01742611 Completed Phase 3 Long-term Study in Chronic Kidney Disease Patients With Hyperphosphatemia Not on Dialysis March 2013 April 2015
NCT01759576 Completed Phase 1 A Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Canagliflozin (JNJ-28431754) in Volunteers With Varying Degrees of Kidney Function March 2008 November 2008
NCT01766154 Completed Phase 1 Pharmacokinetic Evaluation of Tirofiban Using a Single High-Dose Bolus In Subjects With Varying Degrees of Renal Function January 2013 March 2013
NCT01791855 Completed Phase 1 PF-04634817 Renal Impairment Study May 10, 2013 September 3, 2013
NCT01858675 Completed N/A Biomarkers Correlation With Volemia March 2012 December 2014
NCT01944852 Completed Phase 4 Efficacy and Safety of a Double Icodextrin Dose in Elderly Incident CAPD Patients on Incremental PD. March 2013 February 28, 2020
NCT02011490 Completed Phase 1 Pharmacokinetics of Sugammadex (MK-8616) in Participants With Moderate and Severe Renal Insufficiency (MK-8616-105) December 11, 2013 June 6, 2014
NCT02039817 Completed Phase 1 PK and PD Study of IDN-6556 in Subjects With Severe Renal Impairment and Matched Healthy Volunteers January 2014 April 2014
NCT02096718 Completed Phase 1 Afatinib in Subjects With Kidney Dysfunction May 2014 December 2014
NCT02148991 Completed Clinical Trial in Patients With Hypertension and Left Ventricular Dysfunction July 2014 January 2017
NCT02172339 Completed Phase 1 The Pharmacokinetic, Safety and Tolerability of Tiotropium in Outpatients With Renal Impairment in Comparison to Healthy Subjects April 1998
NCT02182024 Completed Phase 1 Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate in Patients With and Without Renal Impairment April 2005
NCT02184091 Completed Phase 1 Study to Evaluate the Effects of Underlying Renal or Hepatic Dysfunction on the Pharmacokinetics of Nevirapine January 1999
NCT02699736 Enrolling by invitation EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV January 1994 December 2030
NCT02301312 Not yet recruiting N/A Clinical Study of POSS-PCU Vascular Grafts for Vascular Access April 2021 April 2025
NCT05592847 Not yet recruiting N/A A Study of the Effect of a Nurse Navigator Program on High Risk Patients June 2024 April 2025
NCT03899298 Not yet recruiting Phase 1 Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions September 1, 2019 March 20, 2029
NCT06439862 Not yet recruiting Study of the Quality of Life in School Aged-children With Posterior Urethral Valves July 1, 2025 December 31, 2025
NCT05533645 Not yet recruiting N/A Food Frequency Questionnaire to Assess Sodium Intake February 2023 August 2024
NCT05178602 Not yet recruiting N/A The Effect of TaiChi on Ischemic Burden of Patients With Coronary Heart Disease Complicated With Renal Insufficiency January 1, 2022 December 30, 2024
NCT06001827 Recruiting N/A SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study November 20, 2023 December 2027
NCT05778864 Recruiting Phase 1 A Study of LY3473329 in Participants With Impaired and Normal Renal Function March 17, 2023 October 10, 2024
NCT05242315 Recruiting Phase 4 Extended-Release Tacrolimus Following Liver Transplantation May 15, 2022 February 15, 2034
NCT05222191 Recruiting Phase 2 Spironolactone in CKD Enabled by Chlorthalidone: PILOT February 1, 2022 December 12, 2023
NCT04451018 Recruiting Evaluation of Macro and Microcirculatory Arterial Condition of the Upper Limb in Insufficiently Renal Patients June 17, 2020 June 17, 2025
NCT06431789 Recruiting Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency May 1, 2024 April 30, 2026
NCT05960006 Recruiting A Study to Determine Pharmacokinetic Changes of Ceftriaxone in Patients With Liver Cirrhosis July 10, 2023 September 10, 2024
NCT05640518 Recruiting External Validation of the VExUS Score for the Prediction of Acute Renal Failure in Cardiac Surgery December 19, 2022 November 2024
NCT01524276 Recruiting Product Surveillance Registry January 2012 January 2030
NCT05117450 Recruiting N/A Comparison of HYDROLINK™ and HeprAN™ mEmbranes in a Per Dialytic Heparin Weaning Strategy in Chronic Hemodialysis Patients November 17, 2021 December 17, 2024
NCT05784389 Recruiting N/A Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5 March 27, 2023 November 20, 2023
NCT06407154 Recruiting Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study, 2nd Wave May 21, 2024 September 30, 2024
NCT01742702 Recruiting HaemoDYNAMICs in Primary and Secondary Hypertension May 25, 2006 December 31, 2025
NCT05884905 Recruiting N/A Safety of Short Hydration Method for Cisplatin Administration Compared With Conventional Hydration March 7, 2023 March 7, 2025
NCT05428631 Recruiting N/A Tolerability and Safety of CARDIOMEMS™ Intracardiac Continuous Cardiac Hemodynamic Monitoring Device in Patients With Cardio Renal Syndrome With Severe Renal Impairment August 26, 2022 August 26, 2025
NCT06354231 Recruiting Phase 2 DV Combined With Toripalimab for Renal Preservation in Solitary Kidney or Renal Insufficiency or Bilateral Multiple UTUC July 20, 2023 December 30, 2026
NCT04241666 Recruiting Sonographic Examination of Renal Function in Individuals With Long-term Spinal Cord Injury January 5, 2022 February 2025
NCT04754659 Recruiting N/A Renal Function After Stentgraft Treatment Of Abdominal Aortic Aneurysm December 19, 2022 December 2027
NCT01861561 Terminated Phase 4 Low-dose VS High-dose IV Cyclophosphamide for Proliferative LN in Children May 2013 May 2019
NCT01786824 Terminated Phase 3 Preventing Contrast-induced Nephropathy: Evaluating Hydration Strategies and L-carnitine Administration December 2014 August 2015
NCT00575484 Terminated Phase 2 Concentrated Saline Infusions and Increased Dietary Sodium With Diuretics for Heart Failure With Kidney Dysfunction November 2007 July 2008
NCT01957657 Terminated Phase 1 Pharmacokinetics, Safety and Tolerability of the Combination of BI 207127 and Faldaprevir in Renal Impaired Patients October 2013 December 2013
NCT00656266 Terminated Phase 4 Trial of Calcineurin Inhibitor-Sparing Immunosuppression Regimen in Pediatric Liver Transplantation November 2004 November 2005
NCT00721422 Terminated Phase 1 A Single Dose Study Investigating the Elimination as Well as the Tolerability of PD 0332334 in Healthy Subjects as Compared to Patients With Impaired Kidney Function. August 2008 February 2009
NCT00306306 Terminated Phase 2/Phase 3 COOL RCN: Cooling to Prevent Radiocontrast Nephropathy March 2006 August 2007
NCT00745316 Terminated Phase 2 Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency February 2009 January 2010
NCT00338455 Terminated Phase 2 Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC September 2006 October 2007
NCT00927602 Terminated Phase 4 Fondaparinux 1,5 mg for the Prevention of Venous Thromboembolism (VTE) in Medical Patients With Renal Insufficiency April 2009 March 2012
NCT00936247 Terminated Phase 4 Tetraspan 6 Percent (%) Combined With Sterofundin ISO Versus Albumin 5 Percent (%) Combined With Sodium Chloride (NaCL) November 2009 September 2010
NCT00209417 Terminated Phase 4 Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Computed Tomography June 2005 July 2011
NCT01312064 Terminated Phase 4 De Novo Everolimus-based Therapy for Renal Transplantation Using Rituximab Induction April 2011 April 2012
NCT02664155 Terminated Phase 3 Venous Thromboembolism in Renally Impaired Patients and Direct Oral Anticoagulants October 19, 2016 May 30, 2022
NCT04474210 Terminated Phase 1 A Study to Evaluate the Effect of Renal Impairment on JNJ-56136379 in Adult Participants August 19, 2020 November 30, 2020
NCT05961163 Terminated Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study July 24, 2023 September 3, 2023
NCT01105923 Unknown status N/A Study of an Intervention to Improve Problem List Accuracy and Use May 2010 November 2017
NCT00980317 Unknown status N/A A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Third Parties July 2009 June 2014
NCT01722513 Unknown status Phase 4 Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy November 2012 February 2014
NCT05219188 Unknown status PErirenal Adipose Tissue and RenaL Hemodynamics in Patients With Heart Failure With Preserved Ejection Fraction February 1, 2022 August 1, 2022
NCT04002531 Unknown status N/A A One Visit Follow Up of Adults With Fabry Disease Who Started Long-term Enzyme Replacement Therapy As Children November 10, 2018 December 31, 2019
NCT00847275 Unknown status N/A Behaviour and Cognitive Evaluation for Dialysis Elderly Patients (BCDE) July 2008 January 2015
NCT02742207 Unknown status Renal Function Post Cardioversion for Atrial Fibrillation July 11, 2018 December 2020
NCT04126538 Unknown status Phase 1 Pirfenidone Capsule in Patients With Chronic Kidney Disease G2 and G3a Study on Safety and Pharmacokinetics August 27, 2019 June 30, 2022
NCT04903847 Unknown status Phase 4 Changes in Weight, Body Composition and Metabolic Parameters After Discontinuing Dolutegravir or Tenofovir Disproxil February 2, 2021 February 2, 2023
NCT00358046 Unknown status Phase 2 Efficacy and Tolerability of ILY101 in Dialysis Patients With Hyperphosphatemia June 2006
NCT00527059 Unknown status Phase 4 Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure October 2007 March 2008
NCT04391608 Unknown status Phase 4 TDF Dose Adjustment VS. Switching to TAF in TDF-experienced CHB Patients With Renal Impairment November 9, 2019 July 31, 2022
NCT03213821 Unknown status N/A Safety and Efficacy of High Protein Diet Versus GFR Based Protein Diet in Heart Failure Patients With Renal Insufficiency November 1, 2017 December 30, 2019
NCT03767803 Unknown status Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women October 1, 2018 December 31, 2020
NCT02324400 Unknown status Phase 1/Phase 2 Pilot Study for the Evaluation of the Safety and Performance of the RenaSense System in Hospitalized Acute Decompensated Heart Failure Patients January 2015
NCT01001000 Unknown status Colour Coded Duplex Ultrasound of Native Arterio-venous Fistula for Haemodialysis With Venous Pressure Measurement Using Controlled Compression Ultrasound as a Predictor for Shunt Maturation in the Early Postoperative Phase October 2009 October 2010
NCT00994188 Unknown status N/A A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members July 2009 June 2014
NCT02578784 Unknown status N/A DEB-after-Cutting Balloon-PTA in Dialysis Fistula Stenosis October 2015 October 2018
NCT02598635 Unknown status Phase 4 Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis October 2015 June 2017
NCT04581694 Unknown status N/A Transcatheter Implantation of Aortic Bioprosthesis Without the Use of Iodinated Contrast in Patients With Chronic Kidney Disease December 1, 2020 April 1, 2022
NCT04096547 Unknown status Rivaroxaban in Elderly NVAF Patients With or Without Renal Impairment September 25, 2019 August 30, 2022
NCT04116814 Unknown status High Resolution Imaging of Retinal Vessels as a Biomarker of Cardiovascular Disease in Patients With Renal Insufficiency - RI April 21, 2018 March 31, 2022
NCT04119427 Unknown status N/A The Safety and Efficacy of Micro-energy Ultrasound in the Treatment of Renal Insufficiency After Renal Transplantation May 1, 2020 December 31, 2021
NCT00806039 Unknown status N/A Impact of Early Renal Involvement on the Development of Severe In-hospital Renal Failure December 2008 July 2009
NCT00811863 Withdrawn Evaluation of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Following OptiMARK Injection February 2009 May 17, 2012
NCT04598516 Withdrawn Maastricht Investigation of Renal Function in Absence of- and Post- Contrast in Patients With eGFR LEss Than 30 November 1, 2097 November 1, 2099
NCT04150666 Withdrawn N/A The Water Intake Trail and Primary Aldosteronism Postoperation(WIT-PAP) December 1, 2019 December 1, 2020
NCT03545087 Withdrawn Phase 1 A Study of Lanabecestat in Participants With Severe Kidney Impairment Compared to Healthy Participants June 2018 January 2019
NCT01809730 Withdrawn Pilot Study: Cardiovascular Events in High Risk Orthopedic Surgical Patients May 2012 January 2020
NCT03329612 Withdrawn N/A Remote Ischemic Preconditioning in ACS Patients October 26, 2016 December 30, 2018
NCT04597892 Withdrawn Efficacy of Point-Of-Care Creatinine Assays in Patients With eGFR <30 Receiving Intravascular Contrast May 1, 2097 March 1, 2099
NCT04603261 Withdrawn Time to Excretion of Contrast, a Maastricht Prospective Observational Study November 1, 2097 November 1, 2099
NCT01832103 Withdrawn Phase 1 The Pharmacokinetics of MK-7145 Following Single Dose Administration in Participants With Moderate Renal Insufficiency (MK-7145-018) August 2013 December 2013
NCT02325024 Withdrawn Phase 1 A Study to Evaluate the Pharmacokinetics Of Sativex® in Subjects With Severe Renal Impairment or End Stage Renal Disease, Compared to Matched Subjects With Normal Renal Function. January 2016 October 2016
NCT01407900 Withdrawn Phase 1 Effects of Chimeric Natriuretic Peptide Versus Placebo in Stable Heart Failure and Moderate Renal Dysfunction January 2014 February 2014
HPO alt_id (Human Phenotype Ontology)
HP:0000084
HPO alt_id (Human Phenotype Ontology)
HP:0004723
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0000083
MeSH unique ID (MeSH (Medical Subject Headings))
D051437