HRAS HRas proto-oncogene, GTPase
Clinical Significance
| MGeND | ClinVar | |
|---|---|---|
| Pathogenic | 16 | 60 |
| Likely pathogenic | 8 | 56 |
| Benign | 4 | 80 |
| Likely benign | 1 | 476 |
| Conflicting classifications of pathogenicity | 0 | 46 |
| not provided | 55 | 4 |
| Uncertain significance | 6 | 554 |
Ranking
| ClinVar | |
|---|---|
 |
0 |
 |
40 |
 |
260 |
 |
844 |
 |
54 |
Frequency
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
Disease area statistics
Locus Zoom
Variants
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| Target data | : |
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| Variant name | Gene | AA change | CDS | Japanese frequency |
TogoVar | MGeND | Genome | ClinVar | CIViC evidence | DisGeNET entry | COSMIC occurrence |
Prediction | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | Entry | Origin | Annotation | |||||||||||
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MGeND data only
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| Name | MGeND | Type | Genome | Size | Chromosome | Start | Stop | Ref | Alt | ClinVar | Origin | Entry | CIViC evidence | DisGeNET entry | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | ||||||||||||||
Search Word
| Target data | : |
MGeND data only
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| Name | MGeND | Type | Genome | Gene symbol | Chromosome | Genomic start | Genomic stop | Strand | Ref | Alt | ClinVar | Origin | Entry | CIViC evidence | DisGeNET entry | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | |||||||||||||||
| Type | ID |
|---|---|
| SYNONYM | C-BAS/HAS |
| SYNONYM | C-H-RAS |
| SYNONYM | C-HA-RAS1 |
| SYNONYM | CTLO |
| SYNONYM | H-RASIDX |
| SYNONYM | HAMSV |
| SYNONYM | HRAS1 |
| SYNONYM | RASH1 |
| SYNONYM | p21ras |
| MIM | 190020 OMIM |
| HGNC | HGNC:5173 HGNC |
| Ensembl | ENSG00000174775 Ensembl |
| AllianceGenome | HGNC:5173 |
| Descrption | Source | Links |
|---|
| ID | Genome | Chromosome | Start | End | Length |
|---|---|---|---|---|---|
| ENST00000397594.7 | hg38 | chr11 | 532,242 | 534,375 | 2,134 |
| ENST00000397596.6 | hg38 | chr11 | 532,242 | 535,339 | 3,098 |
| ENST00000311189.8 | hg38 | chr11 | 532,242 | 535,576 | 3,335 |
| ENST00000417302.7 | hg38 | chr11 | 532,242 | 535,576 | 3,335 |
| ENST00000451590.5 | hg38 | chr11 | 532,243 | 535,550 | 3,308 |
| ENST00000397594.7 | hg19 | chr11 | 532,242 | 534,375 | 2,134 |
| ENST00000397596.6 | hg19 | chr11 | 532,242 | 535,339 | 3,098 |
| ENST00000311189.8 | hg19 | chr11 | 532,242 | 535,576 | 3,335 |
| ENST00000417302.7 | hg19 | chr11 | 532,242 | 535,576 | 3,335 |
| ENST00000451590.5 | hg19 | chr11 | 532,243 | 535,550 | 3,308 |
| Key | Value |
|---|---|
| strand | - |
| UniProt | OG |
| start | 532,241 |
| Vogelstein | OG |
| Gene Symbol | HRAS |
| Entrez GeneId | 3,265 |
| Chr Band | 11p15.5 |
| end | 535,566 |
| chr | chr11 |
| Name | v-Ha-ras Harvey rat sarcoma viral oncogene homolog |
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