TREM2 triggering receptor expressed on myeloid cells 2
Information
- Symbol
- TREM2
- Type
- protein-coding
- Description
- triggering receptor expressed on myeloid cells 2
- Entrez Gene ID
- 54209
- Genome
- hg19
- Position
- chr6:41,126,246-41,130,854
- Genome
- hg38
- Position
- chr6:41,158,508-41,163,116
- MIM
- 605086 OMIM
- HGNC
- HGNC:17761 HGNC
- Ensembl
- ENSG00000095970 Ensembl
- Links
- NCBI Gene Cards OncoKB
Clinical Significance
| MGeND | ClinVar | |
|---|---|---|
| Pathogenic | 3 | 26 |
| Likely pathogenic | 0 | 18 |
| Benign | 7 | 20 |
| Likely benign | 0 | 114 |
| Conflicting classifications of pathogenicity | 0 | 20 |
| Uncertain significance | 0 | 144 |
Ranking
| ClinVar | |
|---|---|
 |
0 |
 |
0 |
 |
56 |
 |
240 |
 |
6 |
Frequency
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
Disease area statistics
Locus Zoom
Variants
Search Word
| Target data | : |
MGeND data only
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| Variant name | Gene | AA change | CDS | Japanese frequency |
TogoVar | MGeND | Genome | ClinVar | CIViC evidence | DisGeNET entry | COSMIC occurrence |
Prediction | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | Entry | Origin | Annotation | |||||||||||
Search Word
| Target data | : |
MGeND data only
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| Filtering | : |
| Name | MGeND | Type | Genome | Size | Chromosome | Start | Stop | Ref | Alt | ClinVar | Origin | Entry | CIViC evidence | DisGeNET entry | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | ||||||||||||||
Search Word
| Target data | : |
MGeND data only
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| Category | : |
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| Search word | : | |
| Filtering | : |
| Name | MGeND | Type | Genome | Gene symbol | Chromosome | Genomic start | Genomic stop | Strand | Ref | Alt | ClinVar | Origin | Entry | CIViC evidence | DisGeNET entry | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | |||||||||||||||
| Type | ID |
|---|---|
| SYNONYM | PLOSL2 |
| SYNONYM | TREM-2 |
| SYNONYM | Trem2a |
| SYNONYM | Trem2b |
| SYNONYM | Trem2c |
| MIM | 605086 OMIM |
| HGNC | HGNC:17761 HGNC |
| Ensembl | ENSG00000095970 Ensembl |
| AllianceGenome | HGNC:17761 |
| Descrption | Source | Links |
|---|
| ID | Genome | Chromosome | Start | End | Length |
|---|---|---|---|---|---|
| ENST00000373113.8 | hg38 | chr6 | 41,158,508 | 41,163,116 | 4,609 |
| ENST00000373122.8 | hg38 | chr6 | 41,158,506 | 41,163,103 | 4,598 |
| ENST00000338469.3 | hg38 | chr6 | 41,158,507 | 41,163,186 | 4,680 |
| ENST00000373122.8 | hg19 | chr6 | 41,126,244 | 41,130,841 | 4,598 |
| ENST00000338469.3 | hg19 | chr6 | 41,126,245 | 41,130,924 | 4,680 |
| ENST00000373113.8 | hg19 | chr6 | 41,126,246 | 41,130,854 | 4,609 |
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