SDHA succinate dehydrogenase complex flavoprotein subunit A
Information
- Symbol
- SDHA
- Type
- protein-coding
- Description
- succinate dehydrogenase complex flavoprotein subunit A
- Entrez Gene ID
- 6389
- Genome
- hg19
- Position
- chr5:218,435-257,197
- Genome
- hg38
- Position
- chr5:218,320-257,082
- MIM
- 600857 OMIM
- HGNC
- HGNC:10680 HGNC
- Ensembl
- ENSG00000073578 Ensembl
- Links
- NCBI Gene Cards OncoKB
Clinical Significance
| MGeND | ClinVar | |
|---|---|---|
| Pathogenic | 3 | 338 |
| Likely pathogenic | 1 | 206 |
| Benign | 0 | 118 |
| Likely benign | 3 | 1,700 |
| Conflicting classifications of pathogenicity | 0 | 276 |
| not provided | 14 | 4 |
| Uncertain significance | 18 | 2,770 |
Ranking
| ClinVar | |
|---|---|
 |
0 |
 |
0 |
 |
2,160 |
 |
2,834 |
 |
4 |
Frequency
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
Disease area statistics
Locus Zoom
Variants
Search Word
| Target data | : |
MGeND data only
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| Category | : |
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| Filtering | : |
| Variant name | Gene | AA change | CDS | Japanese frequency |
TogoVar | MGeND | Genome | ClinVar | CIViC evidence | DisGeNET entry | COSMIC occurrence |
Prediction | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | Entry | Origin | Annotation | |||||||||||
Search Word
| Target data | : |
MGeND data only
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| Category | : |
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| Search word | : | |
| Filtering | : |
| Name | MGeND | Type | Genome | Size | Chromosome | Start | Stop | Ref | Alt | ClinVar | Origin | Entry | CIViC evidence | DisGeNET entry | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | ||||||||||||||
Search Word
| Target data | : |
MGeND data only
|
| Category | : |
|
| Search word | : | |
| Filtering | : |
| Name | MGeND | Type | Genome | Gene symbol | Chromosome | Genomic start | Genomic stop | Strand | Ref | Alt | ClinVar | Origin | Entry | CIViC evidence | DisGeNET entry | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | |||||||||||||||
| Type | ID |
|---|---|
| SYNONYM | CMD1GG |
| SYNONYM | FP |
| SYNONYM | MC2DN1 |
| SYNONYM | NDAXOA |
| SYNONYM | PGL5 |
| SYNONYM | PPGL5 |
| SYNONYM | SDH1 |
| SYNONYM | SDH2 |
| SYNONYM | SDHF |
| MIM | 600857 OMIM |
| HGNC | HGNC:10680 HGNC |
| Ensembl | ENSG00000073578 Ensembl |
| AllianceGenome | HGNC:10680 |
| Descrption | Source | Links |
|---|
| ID | Genome | Chromosome | Start | End | Length |
|---|---|---|---|---|---|
| ENST00000510361.5 | hg38 | chr5 | 218,318 | 256,679 | 38,362 |
| ENST00000504309.5 | hg38 | chr5 | 218,303 | 256,682 | 38,380 |
| ENST00000264932.11 | hg38 | chr5 | 218,320 | 257,082 | 38,763 |
| ENST00000504309.5 | hg19 | chr5 | 218,418 | 256,797 | 38,380 |
| ENST00000264932.11 | hg19 | chr5 | 218,435 | 257,197 | 38,763 |
| ENST00000510361.5 | hg19 | chr5 | 218,433 | 256,794 | 38,362 |
| Key | Value |
|---|---|
| strand | + |
| UniProt | TSG |
| start | 218,337 |
| Gene Symbol | SDHA |
| Entrez GeneId | 6,389 |
| Chr Band | 5p15 |
| end | 257,196 |
| chr | chr5 |
| Name | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) |
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