TOP2A DNA topoisomerase II alpha

Information
Symbol
TOP2A
Type
protein-coding
Description
DNA topoisomerase II alpha
Entrez Gene ID
7153
Genome
hg19
Position
chr17:38,544,777-38,574,148
Genome
hg38
Position
chr17:40,388,525-40,417,896
MIM
126430 OMIM
HGNC
HGNC:11989 HGNC
Ensembl
ENSG00000131747 Ensembl
Links
NCBI Gene Cards OncoKB
Clinical Significance
MGeND ClinVar
Benign 0 20
Likely benign 0 38
Conflicting classifications of pathogenicity 0 2
protective 0 2
Uncertain significance 0 92
Ranking
ClinVar
0
0
18
120
6
Frequency
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
Disease area statistics
[No Data.]
Locus Zoom
Variants
Search Word
Target data :
MGeND data only
Category :
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Variant name Gene AA change CDS Japanese
frequency		 TogoVar MGeND Genome ClinVar CIViC evidence DisGeNET entry COSMIC
occurrence		 Prediction
Entry Origin Type Annotation Entry Origin Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Size Chromosome Start Stop Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Gene symbol Chromosome Genomic start Genomic stop Strand Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
TypeID
SYNONYM TOP2
SYNONYM TOP2alpha
SYNONYM TOPIIA
SYNONYM TP2A
MIM 126430 OMIM
HGNC HGNC:11989 HGNC
Ensembl ENSG00000131747 Ensembl
AllianceGenome HGNC:11989
DescrptionSourceLinks
IDGenomeChromosomeStartEndLength
ENST00000423485.6 hg38 chr17 40,388,525 40,417,896 29,372
ENST00000423485.6 hg19 chr17 38,544,777 38,574,148 29,372
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