FGFR1 FGFR1 FUSIONS Detail (hg38) (FGFR1)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr8:38,268,656-38,325,363 View the variant detail on this assembly version. |
| hg38 | chr8:38,411,138-38,467,845 |
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
| Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| chronic myelomonocytic leukemia | A |
Diagnostic
|
Supports
|
Negative | Somatic | 5 | 27069254 | Detail | |
| hematologic cancer | A |
Diagnostic
|
Supports
|
Positive | Somatic | 5 | 27069254 | Detail | |
| acute myeloid leukemia | Sunitinib,Sorafenib | D |
Predictive
|
Does Not Support
|
Sensitivity/Response | Somatic | 3 | 21482694 | Detail |
DisGeNET
[No Data.]
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| The 2016 World Health Organization guidelines for the classification of myeloid malignancies uses th... | CIViC Evidence | Detail |
| The 2016 World Health Organization guidelines for the classification of myeloid malignancies and acu... | CIViC Evidence | Detail |
| In a preclinical trial, the AML cell line KG1 with the FGFR1OP2-FGFR1 fusion mutation was treated wi... | CIViC Evidence | Detail |
- Gene
- FGFR1
- Genome
- hg38
- Position
- chr8:38,411,138-38,467,845
- Variant Type
- fusion
- Variant (CIViC) (CIViC Variant)
- FGFR1 FUSIONS
- Transcript 1 (CIViC Variant)
- ENST00000425967.3
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/569
Genome browser