chr1:115256528:> Detail (hg19) (NRAS)

Information

Genome

Assembly Position
hg19 chr1:115,256,528-115,256,530
hg38 chr1:114,713,907-114,713,909 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
[No Data.]
Annotation

Annotations

DescrptionSourceLinks
This work shows that IPC298 melanoma cell line is dependent on NRAS for proliferation and anchorage-... MMMP Detail
This work shows that IPC298 melanoma cell line is dependent on NRAS for growth in vivo MMMP Detail
In vitro the BRAF-shRNA expressing IPC298 cells showed a 20% decrease in proliferation: however, in ... MMMP Detail
In vitro the CRAF-shRNA expressing IPC298 cells showed a 20% decrease in proliferation: however, in ... MMMP Detail
In vitro, the double BRAF and CRAF silencing obtained significant decrease in cell proliferation MMMP Detail
In vivo, the double BRAF and CRAF silencing obtained significant decrease in tumor growth MMMP Detail
Silencing of MEK1, MEK2 or both did not affect proliferation of melanoma cells harboring this NRAS m... MMMP Detail
In vivo, the silencing of PI3K catalytic alpha polypeptide (PIK3CA) did not obtain significant decre... MMMP Detail
In vivo, the double BRAF and PI3K (PIK3CA) silencing obtained significant decrease in tumor growth MMMP Detail
In vivo, the double BRAF and MEK silencing obtained significant decrease in tumor growth MMMP Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
Genome
hg19
Position
chr1:115,256,528-115,256,530
Variant Type
snv
Reference Amino Acid
Q
Alternative Amino Acid
L
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