chr17:37868196:> Detail (hg19) (ERBB2)

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Summary
Information
Links
Disease area statistics
MGeND
ClinVar
CIViC
DisGeNET
Annotation
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Information

Genome

Assembly	Position
hg19	chr17:37,868,196-37,881,332
hg38	chr17:39,711,943-39,725,079

HGVS

RefSeq

Type	Transcript	Protein

Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics	Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star	[No Data.]
Show details

Links

Disease area statistics

[No Data.]

MGeND

[No Data.]

ClinVar

[No Data.]

CIViC

Disease	Drug	EL	ET	ED	CS	VO	TR	Pubmed	Links
bladder carcinoma	Platinum Compound	C	Predictive	Supports	Sensitivity/Response	Somatic	3	25636205	Detail
breast cancer	Neratinib	B	Predictive	Supports	Sensitivity/Response	Somatic	4	28679771	Detail
lung non-small cell carcinoma	Pertuzumab,Trastuzumab	B	Predictive	Supports	Sensitivity/Response	Somatic	2	29320312	Detail

DisGeNET

[No Data.]

Annotation

Annotations

Descrption	Source	Links
In patients with muscle-invasive bladder chancer, a cohort of complete responders to platinum chemot...	CIViC Evidence	Detail
16 patients with HER2-mutated metastatic breast cancer were treated with neratinib monotherapy. Of t...	CIViC Evidence	Detail
The phase 2a MyPathway study assigned patients with HER2, EGFR, BRAF or SHH alterations to treatment...	CIViC Evidence	Detail

Overlapped Transcript Coordinates

Gene	Transcript ID	Exon Number	Chromosome	Start	Stop	Type	Amino Mutation	Transcript Position	Links

Overlapped Transcript

Gene	Transcript ID	Chromosome	Start	Stop	Links

Gene: -
Genome: hg19
Position: chr17:37,868,196-37,881,332
Variant Type: snv
Variant (CIViC) (CIViC Variant): MUTATION
Transcript 1 (CIViC Variant): ENST00000269571.5
Variant URL (CIViC Variant): https://civic.genome.wustl.edu/links/variants/666

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