TBK1 OVEREXPRESSION Detail (hg19) (TBK1)

Go to:

Summary
Information
Links
Disease area statistics
MGeND
ClinVar
CIViC
DisGeNET
Annotation
Genome browser

Information

Genome

Assembly	Position
hg19	chr12:64,845,660-64,895,888
hg38	chr12:64,451,880-64,502,108 View the variant detail on this assembly version.

Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics	Show details

ClinVar

Clinical Significance
Review star	[No Data.]
Show details

Links

Type	Database	ID	Link
Gene	MIM	604834	OMIM
	HGNC	11584	HGNC
	Ensembl	ENSG00000183735	Ensembl
	NCBI		NCBI
	Gene Cards		Gene Cards
	OncoKB		OncoKB

Type	Database	ID	Link
Variant	TogoVar
	COSMIC
	MONDO

Disease area statistics

[No Data.]

MGeND

[No Data.]

ClinVar

[No Data.]

CIViC

Disease	Drug	EL	ET	ED	CS	VO	TR	Pubmed	Links
melanoma	AZ909,Selumetinib	D	Predictive	Supports	Sensitivity/Response	N/A	2	24962318	Detail

DisGeNET

[No Data.]

Annotation

Annotations

Descrption	Source	Links
Preclinical study in melanoma cell lines. TBK1 depletion (siRNA) inhibited migration and invasion, w...	CIViC Evidence	Detail

Overlapped Transcript Coordinates

Gene	Transcript ID	Exon Number	Chromosome	Start	Stop	Type	Amino Mutation	Transcript Position	Links

Overlapped Transcript

Gene	Transcript ID	Chromosome	Start	Stop	Links

Gene: TBK1
Genome: hg19
Position: chr12:64,845,660-64,895,888
Variant Type: cnv
Variant (CIViC) (CIViC Variant): OVEREXPRESSION
Transcript 1 (CIViC Variant): ENST00000331710.5
Variant URL (CIViC Variant): https://civic.genome.wustl.edu/links/variants/483

Genome browser