chr2:220283222:C>T Detail (hg19) (DES)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr2:220,283,222-220,283,222 |
| hg38 | chr2:219,418,500-219,418,500 View the variant detail on this assembly version. |
HGVS
| Type | Transcript | Protein |
|---|---|---|
| RefSeq | NM_001927.3:c.38C>T | NP_001918.3:p.Ser13Phe |
| Ensemble | ENST00000373960.4:c.38C>T | ENST00000373960.4:p.Ser13Phe |
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
| Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
|---|---|---|---|---|---|
|
|
2011-09-07 | criteria provided, single submitter | Primary dilated cardiomyopathy |
|
Detail |
|
|
2017-03-02 | criteria provided, single submitter | not provided |
|
Detail |
|
|
2022-03-16 | criteria provided, multiple submitters, no conflicts | Desmin-related myofibrillar myopathy |
|
Detail |
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.564 | MYOPATHY, MYOFIBRILLAR, DESMIN-RELATED | NA | CLINVAR | Detail | |
| 0.440 | CARDIOMYOPATHY, DILATED, 1I | NA | CLINVAR | Detail | |
| 0.023 | myopathy | Characterization of a novel S13F desmin mutation associated with desmin myopathy... | BeFree | 18061454 | Detail |
| <0.001 | Heart block | Characterization of a novel S13F desmin mutation associated with desmin myopathy... | BeFree | 18061454 | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NM_001927.4(DES):c.38C>T (p.Ser13Phe) AND Primary dilated cardiomyopathy | ClinVar | Detail |
| NM_001927.4(DES):c.38C>T (p.Ser13Phe) AND not provided | ClinVar | Detail |
| NM_001927.4(DES):c.38C>T (p.Ser13Phe) AND Desmin-related myofibrillar myopathy | ClinVar | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Characterization of a novel S13F desmin mutation associated with desmin myopathy and heart block in ... | DisGeNET | Detail |
| Characterization of a novel S13F desmin mutation associated with desmin myopathy and heart block in ... | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs62636495 dbSNP
- Genome
- hg19
- Position
- chr2:220,283,222-220,283,222
- Variant Type
- snv
- Reference Allele
- C
- Alternative Allele
- T
Genome browser
