chr12:25245321:G>A Detail (hg38) (KRAS)

Information

Genome

Assembly Position
hg19 chr12:25,398,255-25,398,255 View the variant detail on this assembly version.
hg38 chr12:25,245,321-25,245,321

HGVS

Type Transcript Protein
RefSeq NM_004985.4:c.64C>T NP_004976.2:p.Gln22Ter
NM_033360.3:c.64C>T NP_203524.1:p.Gln22Ter
Ensemble ENST00000256078.10:c.64C>T ENST00000256078.10:p.Gln22Ter
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Type Database ID Link
Gene MIM 190070 OMIM
HGNC 6407 HGNC
Ensembl ENSG00000133703 Ensembl
NCBI NCBI
Gene Cards Gene Cards
OncoKB OncoKB
Type Database ID Link
Variant TogoVar
COSMIC COSM33721 COSMIC
MONDO
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
Disease Drug EL ET ED CS VO TR Pubmed Links
colon mucinous adenocarcinoma Panitumumab C Predictive Supports Resistance Somatic 2 19661358 Detail
DisGeNET
[No Data.]
Annotation

Annotations

DescrptionSourceLinks
A 43-year-old female was diagnosed with an adenocarcinoma of the ascending colon and received 6-mont... CIViC Evidence Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
Genome
hg38
Position
chr12:25,245,321-25,245,321
Variant Type
snv
Reference Allele
G
Alternative Allele
A
Variant (CIViC) (CIViC Variant)
Q22*
Transcript 1 (CIViC Variant)
ENST00000256078.4
Variant URL (CIViC Variant)
https://civic.genome.wustl.edu/links/variants/479
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