chrM:8363:G>A Detail (hg38) (MT-TK)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chrM:8,364-8,364 View the variant detail on this assembly version. |
| hg38 | chrM:8,363-8,363 |
HGVS
[No Data.]
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
ClinVar
| Clinical Significance |
|
| Review star | ![]() |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
| Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
|---|---|---|---|---|---|
|
|
1996-05-01 | no assertion criteria provided | Cardiomyopathy and Deafness |
|
Detail |
|
|
no assertion provided | Leigh syndrome |
|
Detail | |
|
|
no assertion provided | MERRF syndrome |
|
Detail | |
|
|
2022-05-04 | criteria provided, multiple submitters, no conflicts | Juvenile myopathy, encephalopathy, lactic acidosis AND stroke |
|
Detail |
|
|
2023-03-13 | reviewed by expert panel | Mitochondrial disease |
|
Detail |
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.121 | Leigh disease | NA | CLINVAR | Detail | |
| 0.124 | MERRF syndrome | NA | CLINVAR | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NC_012920.1(MT-TK):m.8363G>A AND Cardiomyopathy and Deafness | ClinVar | Detail |
| NC_012920.1(MT-TK):m.8363G>A AND Leigh syndrome | ClinVar | Detail |
| NC_012920.1(MT-TK):m.8363G>A AND MERRF syndrome | ClinVar | Detail |
| NC_012920.1(MT-TK):m.8363G>A AND Juvenile myopathy, encephalopathy, lactic acidosis AND stroke | ClinVar | Detail |
| NC_012920.1(MT-TK):m.8363G>A AND Mitochondrial disease | ClinVar | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
- Gene
- -
- dbSNP
- rs118192100 dbSNP
- Genome
- hg38
- Position
- chrM:8,363-8,363
- Variant Type
- snv
- Reference Allele
- G
- Alternative Allele
- A
Genome browser
