Annotation Detail

Information
Associated Genes
CAV3
Associated Variants
CAV3 p.Pro105Leu (p.P105L) ( ENST00000343849.3, ENST00000397368.2 )
CAV3 p.Pro105Leu (p.P105L) ( ENST00000343849.3, ENST00000397368.2 )
Associated Disease
hypertrophic cardiomyopathy
Source Database
DisGeNET
Description
Overexpression of P104L mutant caveolin-3 in mice develops hypertrophic cardiomyopathy with enhanced contractility in association with increased endothelial nitric oxide synthase activity.
Pubmed
14645200
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2004
Drugs