Annotation Detail
Information
- Associated Genes
- LEP
- Associated Variants
-
LEP MUTATION
LEP MUTATION - Associated Disease
- hyperglycemia
- Source Database
- DisGeNET
- Description
- Black and tan, brachyury (BTBR) mice deficient for the leptin receptor (ob/ob) develop many of the pathological features of human DN and, remarkably, treatment with exogenous leptin ameliorates hyperglycaemia, albuminuria and glomerulosclerosis.
- Pubmed
- 25034792
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00217153497664243
Drugs