Annotation Detail

Information
Associated Genes
LEP
Associated Variants
LEP MUTATION
LEP MUTATION
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
When leptin and leptin receptor genes were considered together, synergistic interaction was observed between the two genes leading to hypertension, while the polymorphism at leptin gene and obesity was correlated.
Pubmed
24171506
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN,RGD
DisGENET score for the Gene Disease association
0.240158379459401
Drugs