Annotation Detail

Information
Associated Genes
AKT1
Associated Variants
AKT1 MUTATION
AKT1 MUTATION
Associated Disease
Myeloid Leukemia, Chronic
Source Database
DisGeNET
Description
The present article provides an overview of our current knowledge about the critical role of AKT and STAT5 in the pathophysiology of chronic myeloid leukemia and systemic mastocytosis and on their potential value as therapeutic targets in these neoplasms.
Pubmed
24598853
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00326723398662778
Drugs