Annotation Detail

Information
Associated Genes
IKBKB
Associated Variants
IKBKB MUTATION
IKBKB MUTATION
Associated Disease
lymphoma
Source Database
DisGeNET
Description
The novel IKK2 inhibitor LY2409881 potently synergizes with histone deacetylase inhibitors in preclinical models of lymphoma through the downregulation of NF-κB.
Pubmed
25355930
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs