Annotation Detail
Information
- Associated Genes
- PTGES
- Associated Variants
-
PTGES MUTATION
PTGES MUTATION - Associated Disease
- Degenerative polyarthritis
- Source Database
- DisGeNET
- Description
- These results indicate that H3K9 demethylation by LSD1 contributes to IL-1β-induced mPGES-1 expression and suggest that this pathway could be a potential target for pharmacological intervention in the treatment of OA and possibly other arthritic conditions.
- Pubmed
- 24886859
- Section of the abstract supporting the evidence
- CONCLUSION
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 13
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00435300147494899
Drugs