Annotation Detail

Information
Associated Genes
VKORC1
Associated Variants
VKORC1 MUTATION
VKORC1 MUTATION
Associated Disease
Vitamin K Deficiency
Source Database
DisGeNET
Description
Functional limitations for the vitamin K cycle, caused either by mutations in gamma-glutamyl carboxylase or vitamin K epoxide reductase genes, result in hereditary deficiency of vitamin K-dependent coagulation factors (VKCFD1 and VKCFD2, respectively).
Pubmed
25151188
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs