Annotation Detail

Information
Associated Genes
IKBKB
Associated Variants
IKBKB MUTATION
IKBKB MUTATION
Associated Disease
T-Cell Lymphoma
Source Database
DisGeNET
Description
To evaluate the pharmacologic activity of a novel inhibitor of IκB kinase β (IKK2), LY2409881, in preclinical models of B- and T-cell lymphoma, as a single agent and in combination with histone deacetylase (HDAC) inhibitors.
Pubmed
25355930
Section of the abstract supporting the evidence
PURPOSE
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs