Annotation Detail
Information
- Associated Genes
- IKBKB
- Associated Variants
-
IKBKB MUTATION
IKBKB MUTATION - Associated Disease
- Tumor Progression
- Source Database
- DisGeNET
- Description
- Here we report that the let7 repressor LIN28B and its regulator IKBKB (IKKβ) sustain cancer cell stemness by interacting with the Wnt/TCF7L2 (TCF4) signaling pathway to promote cancer progression.
- Pubmed
- 25744721
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs