Annotation Detail
Information
- Associated Genes
- IKBKB
- Associated Variants
-
IKBKB MUTATION
IKBKB MUTATION - Associated Disease
- pancreatic carcinoma
- Source Database
- DisGeNET
- Description
- Transfection of PAK4-silenced PC cells with constitutively-active mutant of IKKβ, an upstream kinase of IκBα, leads to restoration of NF-κB activity and PC cell growth.
- Pubmed
- 25238288
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs