Annotation Detail

Information
Associated Genes
AKT1
Associated Variants
AKT1 MUTATION
AKT1 MUTATION
Associated Disease
Solid tumour
Source Database
DisGeNET
Description
Impaired fatty acid synthesis was associated with reduced solid tumor cell proliferation, the formation of cystic lesions in some animals, and decreased phosphorylation of Src and protein kinase B (Akt).
Pubmed
25472762
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs