Annotation Detail

Information
Associated Genes
AKT1
Associated Variants
AKT1 MUTATION
AKT1 MUTATION
Associated Disease
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Source Database
DisGeNET
Description
PTEN and NOTCH1 mutations were almost mutually exclusive, while IL7R and WT1 mutations were rare in pediatric T-ALL and PTPN11 and AKT1 mutations were infrequent in adult T-ALL.
Pubmed
26341754
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00453856695524446
Drugs