Annotation Detail
Information
- Associated Genes
- PRDX2
- Associated Variants
-
PRDX2 MUTATION
PRDX2 MUTATION - Associated Disease
- liver carcinoma
- Source Database
- DisGeNET
- Description
- Furthermore, the silencing of Prx I or Prx II significantly enhances the cytotoxic activity of adenanthin on HCC, whereas the ectopic expression of Prx I and Prx II but not their mutants of adenanthin-bound cysteines can rescue adenanthin-induced cytotoxicity in Prxs-silenced HCC cells.
- Pubmed
- 25188510
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,CTD_human
- DisGENET score for the Gene Disease association
- 0.120814325616241
Drugs