Annotation Detail

Information
Associated Genes
LEP
Associated Variants
LEP MUTATION
LEP MUTATION
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
Leptin induces SK1 expression and activation in ER-negative breast cancer cell lines MDAMB-231 and BT-549, but not in ER-positive cell lines.
Pubmed
25482303
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0229206693865844
Drugs