Annotation Detail
Information
- Associated Genes
- AKT1
- Associated Variants
-
AKT1 MUTATION
AKT1 MUTATION - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- As expected, rapamycin inhibition of mTOR results in feedback activation of AKT in breast cancer cell lines.
- Pubmed
- 25023728
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,UNIPROT
- DisGENET score for the Gene Disease association
- 0.150401489672994
Drugs