Annotation Detail
Information
- Associated Genes
- PMEL
- Associated Variants
- PMEL UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Inhibition of melanosome related protein gp100 leads to reduced drug sequestration into melanosomes and following drug exocytosis through the folate receptor alpha
- MMMP State
- downregulated by
- MMMP Molecule
- gp100
- MMMP Molecule Alias
- Pmel-17
- MMMP Modifier
- gp100 siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Methotrexate
- MMMP Drug Alias
- MTX
- MMMP Model
- 3
- MMMP Reference
- Sánchez del Campo L, Pigment Cell Melanoma Res 2009, 22:588-600
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Methotrexate | Sensitivity | true |