JQ1

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Information
Drug Name
JQ1
Description
Entry(CIViC)
4
CIViC
Disease Mutation EL ET ED CS VO TR Pubmed Links
uveal melanoma GNAQ MUTATION GNAQ MUTATION D Predictive Supports Sensitivity/Response Somatic 2 26397223 Detail
uveal melanoma GNA11 MUTATION GNA11 MUTATION D Predictive Supports Sensitivity/Response Somatic 1 26397223 Detail
multiple myeloma MYCL EXPRESSION MYCL EXPRESSION D Predictive Supports Sensitivity/Response N/A 1 27276402 Detail
NUT midline carcinoma BRD4 BRD4-NUTM1 D Predictive Supports Sensitivity/Response Somatic 3 20871596 Detail
Annotation
Description Associated Genes Associated Variants Sensitivity Supported Source Links
Preclinical study in uveal melanoma cell lines. Ce... GNAQ GNAQ MUTATION GNAQ MUTATION Sensitivity true CIViC Evidence detail
Preclinical study in uveal melanoma cell lines. Ce... GNA11 GNA11 MUTATION GNA11 MUTATION Sensitivity true CIViC Evidence detail
Four myeloma cell lines were treated with two diff... MYCL MYCL EXPRESSION MYCL EXPRESSION Sensitivity true CIViC Evidence detail
Treatment of the patient-derived 797 NMC cell line... BRD4 BRD4 BRD4-NUTM1 Sensitivity true CIViC Evidence detail