chr14:64150934:> Detail (hg19)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr14:64,150,934-64,194,783 |
| hg38 | chr14:63,684,216-63,728,065 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | squamous cell carcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant tumor of cervix | NA | BeFree | Detail | |
| <0.001 | colorectal carcinoma | Taken together, this study has revealed miR-27a as a tumor suppressor and has id... | BeFree | 25166914 | Detail |
| <0.001 | Crohn Disease | NA | BeFree | Detail | |
| <0.001 | Diabetes | Expression of the bone sialoproteins, secreted phosphoprotein 1 (SPP1; osteopont... | BeFree | 24715035 | Detail |
| <0.001 | diabetes mellitus | Expression of the bone sialoproteins, secreted phosphoprotein 1 (SPP1; osteopont... | BeFree | 24715035 | Detail |
| <0.001 | Diabetes Mellitus, Insulin-Dependent | NA | BeFree | Detail | |
| <0.001 | Diabetes Mellitus, Non-Insulin-Dependent | Type 2 diabetes is associated with increased expression of APOE, BAX, MMP1, NFKB... | BeFree | 23337395 | Detail |
| 0.002 | Muscular Dystrophy, Duchenne | Validation of genetic modifiers for Duchenne muscular dystrophy: a multicentre s... | BeFree | 25476005 | Detail |
| 0.002 | Muscular Dystrophy, Duchenne | We confirmed relationships between the gene (SPP1) and Duchenne muscular dystrop... | BeFree | 25570735 | Detail |
| 0.002 | Muscular Dystrophy, Duchenne | We studied the effects of LTBP4 and SPP1 polymorphisms on age at loss of ambulat... | BeFree | 25641372 | Detail |
| <0.001 | endometriosis | NA | BeFree | Detail | |
| <0.001 | Glioma | Glioma-associated microglia/macrophages display an expression profile different ... | BeFree | 25658639 | Detail |
| 0.120 | IgA glomerulonephritis | NA | CTD_human | Detail | |
| <0.001 | Histiocytosis, Langerhans-Cell | NA | BeFree | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| <0.001 | Inflammatory Bowel Diseases | NA | BeFree | Detail | |
| <0.001 | Lupus Erythematosus, Systemic | NA | BeFree | Detail | |
| <0.001 | Lyme disease | Results showed a significant majority of patients co-infected with Borrelia spec... | BeFree | 24848130 | Detail |
| <0.001 | melanoma | NA | BeFree | Detail | |
| <0.001 | multiple sclerosis | NA | BeFree | Detail | |
| <0.001 | muscular dystrophy | NA | BeFree | Detail | |
| 0.002 | Neoplasm Metastasis | SPP1 was the only molecule whose over-expression resulted statistically related ... | BeFree | 25077564 | Detail |
| <0.001 | neurofibromatosis 1 | SPP1 is associated with malignant transformation in NF1-associated MPNSTs and co... | BeFree | 25884485 | Detail |
| <0.001 | acoustic neuroma | NA | BeFree | Detail | |
| <0.001 | Osteoarthritis of hip | Association of SPP1 promoter variants with hip osteoarthritis susceptibility in ... | BeFree | 25796600 | Detail |
| <0.001 | osteoporosis | NA | BeFree | Detail | |
| <0.001 | osteosarcoma | NA | BeFree | Detail | |
| 0.120 | Peripheral neuropathy | NA | CTD_human | Detail | |
| <0.001 | Pleural effusion disorder | NA | BeFree | Detail | |
| <0.001 | pseudoxanthoma elasticum | NA | BeFree | Detail | |
| <0.001 | rhabdomyosarcoma | NA | BeFree | Detail | |
| <0.001 | pigmented villonodular synovitis | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
| <0.001 | Tumor Progression | We have previously demonstrated that CBX7 is able to inhibit the expression of t... | BeFree | 25595895 | Detail |
| <0.001 | Gastrointestinal Stromal Tumors | NA | BeFree | Detail | |
| <0.001 | Papillary thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | Metastatic melanoma | The expression profiles for the 12 biomarkers were poorly conserved throughout t... | BeFree | 25586991 | Detail |
| <0.001 | Primary central nervous system lymphoma | SPP1 may play a key role in CNS tropism of primary CNS lymphoma. | BeFree | 26026093 | Detail |
| <0.001 | cervix carcinoma | NA | BeFree | Detail | |
| <0.001 | Nevus elasticus | NA | BeFree | Detail | |
| <0.001 | Osteosarcoma of bone | NA | BeFree | Detail | |
| <0.001 | Carcinogenesis | Tumor suppressor microRNA-27a in colorectal carcinogenesis and progression by ta... | BeFree | 25166914 | Detail |
| <0.001 | allergic symptom | NA | BeFree | Detail | |
| <0.001 | adult acute lymphocytic leukemia | NA | BeFree | Detail | |
| <0.001 | malignant peripheral nerve sheath tumor | SPP1 is associated with malignant transformation in NF1-associated MPNSTs and co... | BeFree | 25884485 | Detail |
| <0.001 | malignant pleural mesothelioma | NA | BeFree | Detail | |
| <0.001 | colorectal cancer | Taken together, this study has revealed miR-27a as a tumor suppressor and has id... | BeFree | 25166914 | Detail |
| <0.001 | Myeloproliferative disorder, chronic, with eosinophilia | NA | BeFree | Detail | |
| <0.001 | liver carcinoma | NA | BeFree | Detail | |
| <0.001 | rheumatoid arthritis | We hypothesised that SPP1 may contribute to the severity of joint destruction in... | BeFree | 24936586 | Detail |
| <0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Taken together, this study has revealed miR-27a as a tumor suppressor and has identified SGPP1 and S... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Expression of the bone sialoproteins, secreted phosphoprotein 1 (SPP1; osteopontin), and integrin-bi... | DisGeNET | Detail |
| Expression of the bone sialoproteins, secreted phosphoprotein 1 (SPP1; osteopontin), and integrin-bi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Type 2 diabetes is associated with increased expression of APOE, BAX, MMP1, NFKB1, PDGFB, SPP1, and ... | DisGeNET | Detail |
| Validation of genetic modifiers for Duchenne muscular dystrophy: a multicentre study assessing SPP1 ... | DisGeNET | Detail |
| We confirmed relationships between the gene (SPP1) and Duchenne muscular dystrophy (DMD) from a prev... | DisGeNET | Detail |
| We studied the effects of LTBP4 and SPP1 polymorphisms on age at loss of ambulation (LoA) in a multi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polar... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Results showed a significant majority of patients co-infected with Borrelia species (30/110; 27 %), ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| SPP1 was the only molecule whose over-expression resulted statistically related to poor outcome rega... | DisGeNET | Detail |
| SPP1 is associated with malignant transformation in NF1-associated MPNSTs and could prove to be an i... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Association of SPP1 promoter variants with hip osteoarthritis susceptibility in Chinese population. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We have previously demonstrated that CBX7 is able to inhibit the expression of the SPP1 gene, encodi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The expression profiles for the 12 biomarkers were poorly conserved throughout these studies with on... | DisGeNET | Detail |
| SPP1 may play a key role in CNS tropism of primary CNS lymphoma. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Tumor suppressor microRNA-27a in colorectal carcinogenesis and progression by targeting SGPP1 and Sm... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| SPP1 is associated with malignant transformation in NF1-associated MPNSTs and could prove to be an i... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Taken together, this study has revealed miR-27a as a tumor suppressor and has identified SGPP1 and S... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We hypothesised that SPP1 may contribute to the severity of joint destruction in RA, specifically in... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- Genome
- hg19
- Position
- chr14:64,150,934-64,194,783
- Variant Type
- snv
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