chr2:121530929:G>A Detail (hg38) (CLASP1, RNU4ATAC)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr2:122,288,505-122,288,505 View the variant detail on this assembly version. |
| hg38 | chr2:121,530,929-121,530,929 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
| RefSeq | NM_015282.2:c.196-604C>T | |
| NM_001142274.1:c.196-604C>T | ||
| NM_001142273.1:c.196-604C>T |
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
| JP | HGVD:[No Data.] |
| ToMMo:<0.001 | |
| NCBN:[No Data.] | |
| NCBN(Hondo):[No Data.] | |
| NCBN(Ryukyu):[No Data.] | |
| East asia | ExAC:<0.001 |
Prediction
ClinVar
| Clinical Significance | Conflicting classifications of pathogenicity |
| Review star | ![]() |
| Show details | |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
| Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
|---|---|---|---|---|---|
|
|
2011-04-08 | no assertion criteria provided | Osteodysplastic primordial dwarfism, type 1 |
|
Detail |
|
|
2022-08-09 | criteria provided, conflicting interpretations | not provided |
|
Detail |
|
|
2021-05-07 | criteria provided, single submitter | Roifman syndrome |
|
Detail |
CIViC
[No Data.]
DisGeNET
[No Data.]
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NM_001395891.1(CLASP1):c.196-604C>T AND Osteodysplastic primordial dwarfism, type 1 | ClinVar | Detail |
| NM_001395891.1(CLASP1):c.196-604C>T AND not provided | ClinVar | Detail |
| NM_001395891.1(CLASP1):c.196-604C>T AND Roifman syndrome | ClinVar | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs181195449 dbSNP
- Genome
- hg38
- Position
- chr2:121,530,929-121,530,929
- Variant Type
- snv
- Reference Allele
- G
- Alternative Allele
- A
- East Asian Homozygous Counts (ExAC)
- 0
- East Asian Allele Frequency (ExAC)
- 0.0
- ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- PASS
- Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- rs181195449
- Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 0.0001
- Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 2
- Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 16760
- East Asian Chromosome Counts (ExAC)
- 134
- East Asian Allele Counts (ExAC)
- 0
- East Asian Heterozygous Counts (ExAC)
- 0
- Chromosome Counts in All Race (ExAC)
- 10764
- Allele Counts in All Race (ExAC)
- 1
- Heterozygous Counts in All Race (ExAC)
- 1
- Homozygous Counts in All Race (ExAC)
- 0
- Allele Frequency in All Race (ExAC)
- 9.29022668153103E-5
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